Liposome-encapsulated hemoglobin ameliorates impairment of fear memory and hippocampal dysfunction after cerebral ischemia in rats

Journal of Pharmacological Sciences

Volumn 114, Issue 4, 2010, Pages 409-419

  Hamadate, Naobumi ^a   Yamaguchi, Taku ^a   Sugawara, Aya ^a   Togashi, Hiroko ^b   Izumi, Takeshi ^a   Yoshida, Takayuki ^a   Ohmura, Yu ^a   Yoshioka, Mitsuhiro ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

Artificial oxygen carrier; Contextual fear conditioning; Hippocampus; Ischemia; Liposome encapsulated hemoglobin

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HEMOGLOBIN; LIPOSOME; TRM 645; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BRAIN BLOOD FLOW; BRAIN DYSFUNCTION; CELL DENSITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENCAPSULATION; HIPPOCAMPAL CA1 REGION; HYPEROXIA; IMMUNOHISTOCHEMISTRY; LIPOSOMAL DELIVERY; LOCOMOTION; MALE; MAZE TEST; MEMORY DISORDER; NEUROPROTECTION; NONHUMAN; OPEN FIELD TEST; OXYGEN TISSUE LEVEL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; TRANSIENT ISCHEMIC ATTACK;

EID: 79951626938     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10207FP     Document Type: Article

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