Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: Essential role of astrocyte-derived plasminogen activator inhibitor-1

Neurochemistry International

Volumn 58, Issue 3, 2011, Pages 423-433

  Kim, Ji Woon ^a,b   Lee, Sung Hoon ^a,b   Ko, Hyun Myung ^b   Kwon, Kyoung Ja ^a,b   Cho, Kyu Suk ^a,b   Choi, Chang Soon ^a,b   Park, Jin Hee ^a,b   Kim, Hahn Young ^b   Lee, Jongmin ^b   Han, Seol Heui ^b   Ignarro, Louis J ^b,c   Cheong, Jae Hoon ^d   Kim, Won Ki ^e   Shin, Chan Young ^a,b  

^a Konkuk University   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Sahmyook University   (South Korea)

^e Korea University College of Medicine   (South Korea)

Author keywords

Astrocytes; Biphasic; LPS; MCAO; PAI 1; tPA

Indexed keywords

GLUTAMIC ACID; LIPOPOLYSACCHARIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; HYPOXIA; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; REGULATORY MECHANISM; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HYPOXIA-ISCHEMIA, BRAIN; INFLAMMATION; MALE; NEURONS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, SPRAGUE-DAWLEY; TISSUE PLASMINOGEN ACTIVATOR; UP-REGULATION;

RATTUS;

EID: 79951581353     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2010.12.020     Document Type: Article

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