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Volumn 25, Issue 6, 2008, Pages 695-707

Uridine protects cortical neurons from glucose deprivation-induced death: Possible role of uridine phosphorylase

Author keywords

Cortical neuron; Glucose deprivation; Middle cerebral artery occlusion reperfusion; Uridine; Uridine phosphorylase

Indexed keywords

5 (PHENYLTHIO)ACYCLOURIDINE; ADENOSINE TRIPHOSPHATE; GLUCOSE; MESSENGER RNA; NITROBENZYLTHIOINOSINE; URIDINE; URIDINE DERIVATIVE; URIDINE PHOSPHORYLASE;

EID: 46349086123     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2007.0409     Document Type: Article
Times cited : (30)

References (38)
  • 1
    • 0035909948 scopus 로고    scopus 로고
    • Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically generated ATP in astrocyte protection
    • Almeida, A., Almeida, J., Bolanos, J.P., and Moncada, S. (2001). Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection. Proc. Natl. Acad. Sci. USA 98, 15294-15299.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 15294-15299
    • Almeida, A.1    Almeida, J.2    Bolanos, J.P.3    Moncada, S.4
  • 2
    • 0020541484 scopus 로고
    • Effect of uridine supply on glycogen resynthesis after ischaemia in the isolated perfused rat heart
    • Aussedat, J. (1983). Effect of uridine supply on glycogen resynthesis after ischaemia in the isolated perfused rat heart. Cardiovasc. Res. 17, 145-151.
    • (1983) Cardiovasc. Res , vol.17 , pp. 145-151
    • Aussedat, J.1
  • 3
    • 0037155932 scopus 로고    scopus 로고
    • Purine and pyrimidine salvage in whole rat brain
    • Barsotti, C., Tozzi, M.G., and Ipata, P.L. (2002). Purine and pyrimidine salvage in whole rat brain. J. Biol. Chem. 277, 9865-9869.
    • (2002) J. Biol. Chem , vol.277 , pp. 9865-9869
    • Barsotti, C.1    Tozzi, M.G.2    Ipata, P.L.3
  • 4
    • 0029839695 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model
    • Belayev, L., Alonso, O.F., Busto, R., Zhao, W., and Ginsberg, M.D. (1996). Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 27, 1616-1622.
    • (1996) Stroke , vol.27 , pp. 1616-1622
    • Belayev, L.1    Alonso, O.F.2    Busto, R.3    Zhao, W.4    Ginsberg, M.D.5
  • 5
    • 0021246285 scopus 로고
    • Cerebral endogenous substrate utilization during the recovery period after profound hypoglycemia
    • Benzi, G., Villa, R.F., Dossena, M., Vercesi, L., Gorini, A., and Pastoris, O. (1984). Cerebral endogenous substrate utilization during the recovery period after profound hypoglycemia. J. Neurosci. Res. 11, 437-450.
    • (1984) J. Neurosci. Res , vol.11 , pp. 437-450
    • Benzi, G.1    Villa, R.F.2    Dossena, M.3    Vercesi, L.4    Gorini, A.5    Pastoris, O.6
  • 6
    • 0031787637 scopus 로고    scopus 로고
    • In vitro assessment of salvage pathways for pyrimidine bases in rat liver and brain
    • Cappiello, M., Mascia, L., Scolozzi, C., Giorgelli, F., and Ipata, P.L. (1998). In vitro assessment of salvage pathways for pyrimidine bases in rat liver and brain. Biochim. Biophys. Acta 1425, 273-281.
    • (1998) Biochim. Biophys. Acta , vol.1425 , pp. 273-281
    • Cappiello, M.1    Mascia, L.2    Scolozzi, C.3    Giorgelli, F.4    Ipata, P.L.5
  • 7
    • 0027510712 scopus 로고
    • Modulation of calcium current, intracellular calcium levels and cell survival by glucose deprivation and growth factors in hippocampal neurons
    • Cheng, B., McMahon, D.G., and Mattson, M.P. (1993). Modulation of calcium current, intracellular calcium levels and cell survival by glucose deprivation and growth factors in hippocampal neurons. Brain Res. 607, 275-285.
    • (1993) Brain Res , vol.607 , pp. 275-285
    • Cheng, B.1    McMahon, D.G.2    Mattson, M.P.3
  • 8
    • 0242574396 scopus 로고    scopus 로고
    • Energy substrates for neurons during neural activity: A critical review of the astrocyte-neuron lactate shuttle hypothesis
    • Chih, C.P., and Roberts, Jr., E.L. (2003). Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis. J. Cereb. Blood Flow Metab. 23, 1263-1281.
    • (2003) J. Cereb. Blood Flow Metab , vol.23 , pp. 1263-1281
    • Chih, C.P.1    Roberts Jr., E.L.2
  • 9
    • 33747889014 scopus 로고    scopus 로고
    • Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase
    • Choi, J.W., Yoo, B.-K., Shin, C.Y., Ryu, M.-K., Ryu, J.H., El Kouni, M.H., Lee, J.-C., Kim, W.-K., and Ko, K.H. (2006). Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase. Neurosci. Res. 56, 111-118.
    • (2006) Neurosci. Res , vol.56 , pp. 111-118
    • Choi, J.W.1    Yoo, B.-K.2    Shin, C.Y.3    Ryu, M.-K.4    Ryu, J.H.5    El Kouni, M.H.6    Lee, J.-C.7    Kim, W.-K.8    Ko, K.H.9
  • 10
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischemic stroke: An integrated view
    • Dirnagl, U., Ladecola, C., and Moskowitq, M.A. (1999). Pathobiology of ischemic stroke: an integrated view. Trends Neurosci. 22, 391-397.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Ladecola, C.2    Moskowitq, M.A.3
  • 11
    • 0027216810 scopus 로고
    • Glycogen in astrocytes: Possible function as lactate supply for neighboring cells
    • Dringen, R., Gebhardt, R., and Hamprecht, B. (1993). Glycogen in astrocytes: possible function as lactate supply for neighboring cells. Brain Res. 623, 208-214.
    • (1993) Brain Res , vol.623 , pp. 208-214
    • Dringen, R.1    Gebhardt, R.2    Hamprecht, B.3
  • 13
    • 0002204958 scopus 로고
    • Cytidine and uridine requirement of the brain
    • Geiger, A., and Yamasaki, S. (1956). Cytidine and uridine requirement of the brain. J. Neurochem. 1, 93-100.
    • (1956) J. Neurochem , vol.1 , pp. 93-100
    • Geiger, A.1    Yamasaki, S.2
  • 14
    • 0038387947 scopus 로고    scopus 로고
    • Identification of a novel human uridine phosphorylase
    • Johansson, M. (2003). Identification of a novel human uridine phosphorylase. Biochem. Biophys. Res. Commun. 307, 41-46.
    • (2003) Biochem. Biophys. Res. Commun , vol.307 , pp. 41-46
    • Johansson, M.1
  • 15
    • 0031724263 scopus 로고    scopus 로고
    • Adenosine, inosine, and guanosine protect glial cells during glucose deprivation and mitochondrial inhibition: Correlation between protection and ATP preservation
    • Jurkowitz, M.S., Litsky, M.L., Browning, M.J., and Hohl, C.M. (1998). Adenosine, inosine, and guanosine protect glial cells during glucose deprivation and mitochondrial inhibition: correlation between protection and ATP preservation. J. Neurochem. 71, 535-548.
    • (1998) J. Neurochem , vol.71 , pp. 535-548
    • Jurkowitz, M.S.1    Litsky, M.L.2    Browning, M.J.3    Hohl, C.M.4
  • 16
    • 33645857684 scopus 로고    scopus 로고
    • Glutamate and GABA metabolism in transient and permanent middle cerebral artery occlusion in rat: Importance of astrocytes for neuronal survival
    • Håberq, A., Qu, H., and Sonnewald, U. (2006). Glutamate and GABA metabolism in transient and permanent middle cerebral artery occlusion in rat: importance of astrocytes for neuronal survival. Neurochem. Int. 48, 531-540.
    • (2006) Neurochem. Int , vol.48 , pp. 531-540
    • Håberq, A.1    Qu, H.2    Sonnewald, U.3
  • 17
    • 0035164372 scopus 로고    scopus 로고
    • Effects of recombinants tissue plasminogen activator after intraluminal thread occlusion in mice
    • Kilic, E., Bähr, M., and Hermann, D.M. (2001). Effects of recombinants tissue plasminogen activator after intraluminal thread occlusion in mice. Stroke 32, 2641-2647.
    • (2001) Stroke , vol.32 , pp. 2641-2647
    • Kilic, E.1    Bähr, M.2    Hermann, D.M.3
  • 18
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton, P. (1999). Ischemic cell death in brain neurons. Physiol. Rev. 79, 1451-1568.
    • (1999) Physiol. Rev , vol.79 , pp. 1451-1568
    • Lipton, P.1
  • 19
    • 0033550908 scopus 로고    scopus 로고
    • Inosine and guanosine preserve neuronal and glial cell viability in mouse spinal cord cultures during chemical hypoxia
    • Litsky, M.L., Hohl, C.M., Lucas, J.H., and Jurkowitz, M.S. (1999). Inosine and guanosine preserve neuronal and glial cell viability in mouse spinal cord cultures during chemical hypoxia. Brain Res. 821, 426-432.
    • (1999) Brain Res , vol.821 , pp. 426-432
    • Litsky, M.L.1    Hohl, C.M.2    Lucas, J.H.3    Jurkowitz, M.S.4
  • 20
    • 0032828907 scopus 로고    scopus 로고
    • Ribose 1-phosphate and inosine activate uracil salvage in rat brain
    • Mascia, L., Cotrufo, T., Cappiello, M., and Ipata, P.L. (1999). Ribose 1-phosphate and inosine activate uracil salvage in rat brain. Biochim. Biophys. Acta 1472, 93-98.
    • (1999) Biochim. Biophys. Acta , vol.1472 , pp. 93-98
    • Mascia, L.1    Cotrufo, T.2    Cappiello, M.3    Ipata, P.L.4
  • 21
    • 0027322855 scopus 로고
    • Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemia
    • Matsumoto, K., Graf, R., Rosner, G., Taguchi, J., and Heiss, W.D. (1993). Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemia. J. Cereb. Blood Flow Metab. 13, 586-594.
    • (1993) J. Cereb. Blood Flow Metab , vol.13 , pp. 586-594
    • Matsumoto, K.1    Graf, R.2    Rosner, G.3    Taguchi, J.4    Heiss, W.D.5
  • 22
    • 0032971723 scopus 로고    scopus 로고
    • Adenosine prevents the death of mesencephalic dopaminergic neurons by a mechanism that involves astrocytes
    • Michel, P.P., Marien, M., Ruberg, M., Colpaert, F., and Aqid, Y. (1999). Adenosine prevents the death of mesencephalic dopaminergic neurons by a mechanism that involves astrocytes. J. Neurochem. 72, 2074-2082.
    • (1999) J. Neurochem , vol.72 , pp. 2074-2082
    • Michel, P.P.1    Marien, M.2    Ruberg, M.3    Colpaert, F.4    Aqid, Y.5
  • 23
    • 24044467785 scopus 로고    scopus 로고
    • Overexpression of Bcl-xl protects septal neurons from prolonged hypoglycemia and from acute ischemia-like stress
    • Panickar, K.S., Nonner, D., and Barrett, J.N. (2005). Overexpression of Bcl-xl protects septal neurons from prolonged hypoglycemia and from acute ischemia-like stress. Neuroscience 135, 73-80.
    • (2005) Neuroscience , vol.135 , pp. 73-80
    • Panickar, K.S.1    Nonner, D.2    Barrett, J.N.3
  • 24
    • 0034943057 scopus 로고    scopus 로고
    • Pedata, F, Corsi, C, Melani, A, Bordoni, F, and Latini, S, 2001, Adenosine extracellular brain concentrations and role of A2A receptors in ischemia. Ann. NY Acad. Sci. 939, 74-84
    • Pedata, F., Corsi, C., Melani, A., Bordoni, F., and Latini, S. (2001). Adenosine extracellular brain concentrations and role of A2A receptors in ischemia. Ann. NY Acad. Sci. 939, 74-84.
  • 26
    • 0037130273 scopus 로고    scopus 로고
    • Homeostatic control of uridine and the role of uridine phosphorylase: A biological and clinical update
    • Pizzorno, G., Cao, D., Leffert, J.J., Russell, R.L., Zhang, D., and Handschumacher, R.E. (2002). Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update. Biochim. Biophys. Acta 1587, 133-144.
    • (2002) Biochim. Biophys. Acta , vol.1587 , pp. 133-144
    • Pizzorno, G.1    Cao, D.2    Leffert, J.J.3    Russell, R.L.4    Zhang, D.5    Handschumacher, R.E.6
  • 28
    • 0035061113 scopus 로고    scopus 로고
    • Effect of uridine derivatives on myocardial stunning during postischemic reperfusion of rat heart
    • Sapronov, N.S., Eliseev, V.V., and Rodionova, O.M. (2000). Effect of uridine derivatives on myocardial stunning during postischemic reperfusion of rat heart. Bull. Exp. Biol. Med. 130, 411-414.
    • (2000) Bull. Exp. Biol. Med , vol.130 , pp. 411-414
    • Sapronov, N.S.1    Eliseev, V.V.2    Rodionova, O.M.3
  • 29
    • 0036318338 scopus 로고    scopus 로고
    • Adenosine and purine nucleosides protect rat primary astrocytes from peroxynitrite-potentiated, glucose deprivation-induced death: Preservation of intracellular ATP level
    • Shin, C.Y., Jang, E.S., Choi, J.W., Ryu, J.R., Kim, W.K., Kim, H.C., Choi, C.R., and Ko, K.H. (2002). Adenosine and purine nucleosides protect rat primary astrocytes from peroxynitrite-potentiated, glucose deprivation-induced death: Preservation of intracellular ATP level. Exp. Neurol. 176, 175-182.
    • (2002) Exp. Neurol , vol.176 , pp. 175-182
    • Shin, C.Y.1    Jang, E.S.2    Choi, J.W.3    Ryu, J.R.4    Kim, W.K.5    Kim, H.C.6    Choi, C.R.7    Ko, K.H.8
  • 30
    • 0024556434 scopus 로고
    • Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: A unifying hypothesis
    • Siesjö, B.K., and Bengtsson, F. (1988). Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis. J. Cereb. Blood Flow Metab. 9, 127-140.
    • (1988) J. Cereb. Blood Flow Metab , vol.9 , pp. 127-140
    • Siesjö, B.K.1    Bengtsson, F.2
  • 31
    • 0027058922 scopus 로고
    • Physiological coupling of glial glycogen metabolism to neuronal activity in brain
    • Swanson, R.A. (1992). Physiological coupling of glial glycogen metabolism to neuronal activity in brain. Can. J. Physiol. Pharmacol. 70, S138-S144.
    • (1992) Can. J. Physiol. Pharmacol , vol.70
    • Swanson, R.A.1
  • 32
    • 0027441567 scopus 로고
    • Glial glycogen stores affect neuronal survival during glucose deprivation in vitro
    • Swanson, R.A., and Choi, D.W. (1993). Glial glycogen stores affect neuronal survival during glucose deprivation in vitro. J. Cereb. Blood Flow Metab. 13, 162-169.
    • (1993) J. Cereb. Blood Flow Metab , vol.13 , pp. 162-169
    • Swanson, R.A.1    Choi, D.W.2
  • 33
    • 0033230119 scopus 로고    scopus 로고
    • Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species
    • Tanaka, J., Toku, K., Zhang, B., Ishihara, K., Sakanaka, M., and Maeda, N. (1999). Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species. Glia 28, 85-96.
    • (1999) Glia , vol.28 , pp. 85-96
    • Tanaka, J.1    Toku, K.2    Zhang, B.3    Ishihara, K.4    Sakanaka, M.5    Maeda, N.6
  • 34
    • 0026523925 scopus 로고
    • The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: Protection by early detrodotoxin or delayed MK-801
    • Tasker, R.C., Coyle, J.T., and Vornov, J.J. (1992). The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early detrodotoxin or delayed MK-801. J. Neurosci. 12, 4298-4308.
    • (1992) J. Neurosci , vol.12 , pp. 4298-4308
    • Tasker, R.C.1    Coyle, J.T.2    Vornov, J.J.3
  • 35
    • 0033150526 scopus 로고    scopus 로고
    • Investigation of possible participation of nucleoside transport systems in the postischemic release of purines and pyrimidines from cold stored liver
    • Toshchakov, V.Y., Bashkina, L.V., and Shumakov, V.I. (1999). Investigation of possible participation of nucleoside transport systems in the postischemic release of purines and pyrimidines from cold stored liver. Cryobiology 38, 261-272.
    • (1999) Cryobiology , vol.38 , pp. 261-272
    • Toshchakov, V.Y.1    Bashkina, L.V.2    Shumakov, V.I.3
  • 36
    • 0035873398 scopus 로고    scopus 로고
    • Pyruvate released by astrocytes protects neurons from copper-catalytzed cysteine neurotoxicity
    • Wang, X.F., and Cynader, M.S. (2001). Pyruvate released by astrocytes protects neurons from copper-catalytzed cysteine neurotoxicity. J. Neurosci. 21, 3322-3331.
    • (2001) J. Neurosci , vol.21 , pp. 3322-3331
    • Wang, X.F.1    Cynader, M.S.2
  • 37
    • 0031238567 scopus 로고    scopus 로고
    • Metabolic pathways for glucose in astrocytes
    • Wiesinger, H., Hamprecht, B., and Dringen, R. (1997). Metabolic pathways for glucose in astrocytes. Glia 21, 22-34.
    • (1997) Glia , vol.21 , pp. 22-34
    • Wiesinger, H.1    Hamprecht, B.2    Dringen, R.3


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