Systems analysis of small signaling modules relevant to eight human diseases

Annals of Biomedical Engineering

Volumn 39, Issue 2, 2011, Pages 621-635

  Benedict, Kelly F ^a   Mac Gabhann, Feilim ^a   Amanfu, Robert K ^a   Chavali, Arvind K ^a   Gianchandani, Erwin P ^a   Glaw, Lydia S ^a   Oberhardt, Matthew A ^a   Thorne, Bryan C ^a   Yang, Jason H ^a   Papin, Jason A ^a   Peirce, Shayn M ^a   Saucerman, Jeffrey J ^a   Skalak, Thomas C ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b University of Virginia   (United States)

Author keywords

Comparative meta analysis; Human disease; Protein signaling; Sensitivity analysis; Systems biology

Indexed keywords

ALZHEIMER'S DISEASE; BINDING AFFINITIES; COMPARATIVE ANALYSIS; DRUG DESIGN; DYSLIPIDEMIAS; EXPERIMENTAL RESEARCH; HEART DISEASE; HIV INFECTION; HUMAN DISEASE; INCREASING PRODUCTION; INFECTIOUS DISEASE; INNATE IMMUNE RESPONSE; META-ANALYSIS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROTEIN SIGNALING; QUANTITATIVE KNOWLEDGE; RAPAMYCIN; ROAD-MAPS; SYSTEM LEVELS; SYSTEMS BIOLOGY; VIRAL INFECTIVITY FACTORS; VIRULENCE FACTORS; WORK SUPPORT;

BINDING ENERGY; CONCENTRATION (PROCESS); CYTOLOGY; DISEASES; PROTEINS; SIGNALING; SYSTEMS ANALYSIS;

SENSITIVITY ANALYSIS;

SIGNAL PEPTIDE;

ARTICLE; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENERAL ASPECTS OF DISEASE; HUMAN; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION; SYSTEM ANALYSIS; SYSTEMS BIOLOGY;

COMPUTER SIMULATION; DISEASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; SYSTEMS ANALYSIS; SYSTEMS BIOLOGY;

EID: 79951553408     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-010-0208-y     Document Type: Article

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