-
1
-
-
0027473729
-
Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37)
-
DOI 10.1038/361362a0
-
Holz IV GG, Kuhtreiber WM, Habener JF. Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37). Nature 1993; 361: 362-365. (Pubitemid 23041630)
-
(1993)
Nature
, vol.361
, Issue.6410
, pp. 362-365
-
-
Holz IV, G.G.1
Kuhtreiber, W.M.2
Habener, J.F.3
-
3
-
-
0032999544
-
Neogenesis vs. apoptosis as main components of pancreatic β cell mass changes in glucose-infused normal and mildly diabetic adult rats
-
Bernard C, Berthault MF, Saulnier C, Ktorza A. Neogenesis vs apoptosis as main components of pancreatic beta cell mass changes in glucose-infused normal and mildly diabetic adult rats. FASEB J 1999; 13: 1195-1205. (Pubitemid 29300365)
-
(1999)
FASEB Journal
, vol.13
, Issue.10
, pp. 1195-1205
-
-
Bernard, C.1
Berthault, M.-F.2
Saulnier, C.3
Ktorza, A.4
-
4
-
-
3242730474
-
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
-
DOI 10.1152/ajpendo.00545.2003
-
Holst JJ, Gromada J. Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab 2004; 287: E199-E206. (Pubitemid 38943883)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.2
-
-
Holst, J.J.1
Gromada, J.2
-
5
-
-
35748957503
-
The physiology of glucagon-like peptide 1
-
DOI 10.1152/physrev.00034.2006
-
Holst JJ. The physiology of glucagon-like peptide 1. Physiol Rev 2007; 87: 1409-1439. (Pubitemid 350041474)
-
(2007)
Physiological Reviews
, vol.87
, Issue.4
, pp. 1409-1439
-
-
Holst, J.J.1
-
6
-
-
0037312818
-
Glucagon-like peptides: Regulators of cell proliferation, differentiation, and apoptosis
-
DOI 10.1210/me.2002-0306
-
Drucker DJ. Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. Mol Endocrinol 2003; 17: 161-171. (Pubitemid 36183142)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.2
, pp. 161-171
-
-
Drucker, D.J.1
-
7
-
-
33644840976
-
Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus
-
DOI 10.1016/j.biocel.2005.07.011, PII S1357272505002566, Diabetes: New Research and Novel Therapies
-
De Leon DD, Crutchlow MF, Ham JY, Stoffers DA. Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus. Int J Biochem Cell Biol 2006; 38: 845-859. (Pubitemid 43363416)
-
(2006)
International Journal of Biochemistry and Cell Biology
, vol.38
, Issue.5-6
, pp. 845-859
-
-
Leon, D.D.D.1
Crutchlow, M.F.2
Ham, J.-Y.N.3
Stoffers, D.A.4
-
8
-
-
0033513455
-
Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats
-
Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999; 48: 2270-2276. (Pubitemid 30395416)
-
(1999)
Diabetes
, vol.48
, Issue.12
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
-
9
-
-
0036312680
-
Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4
-
Tourrel C, Bailbe D, Lacorne M, Meile MJ, Kergoat M, Portha B. Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. Diabetes 2002; 51: 1443-1452. (Pubitemid 34826610)
-
(2002)
Diabetes
, vol.51
, Issue.5
, pp. 1443-1452
-
-
Tourrel, C.1
Bailbe, D.2
Lacorne, M.3
Meile, M.-J.4
Kergoat, M.5
Portha, B.6
-
10
-
-
0027215348
-
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
-
Mentlein R, Gallwitz B, Schmidt WE. Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methio-nine and is responsible for their degradation in human serum. Eur J Biochem 1993; 214: 829-835. (Pubitemid 23188160)
-
(1993)
European Journal of Biochemistry
, vol.214
, Issue.3
, pp. 829-835
-
-
Mentlein, R.1
Gallwitz, B.2
Schmidt, W.E.3
-
11
-
-
24944436267
-
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
-
DOI 10.1007/s00125-005-1847-7
-
Plamboeck A, Holst JJ, Carr RD, Deacon CF. Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig. Diabetologia 2005; 48: 1882-1890. (Pubitemid 41317844)
-
(2005)
Diabetologia
, vol.48
, Issue.9
, pp. 1882-1890
-
-
Plamboeck, A.1
Holst, J.J.2
Carr, R.D.3
Deacon, C.F.4
-
12
-
-
0036171821
-
Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors
-
DOI 10.1128/jvi.76.5.2043-2053.2002
-
Yan Z, Zak R, Luxton GW, Ritchie TC, Bantel-Schaal U, Engelhardt JF. Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors. J Virol 2002; 76: 2043-2053. (Pubitemid 34150672)
-
(2002)
Journal of Virology
, vol.76
, Issue.5
, pp. 2043-2053
-
-
Yan, Z.1
Zak, R.2
Luxton, G.W.G.3
Ritchie, T.C.4
Bantel-Schaal, U.5
Engelhardt, J.F.6
-
13
-
-
0029151404
-
Adeno-associated virus vectors for gene therapy
-
Flotte TR, Carter BJ. Adeno-associated virus vectors for gene therapy. Gene Therapy 1995; 2: 357-362.
-
(1995)
Gene Therapy
, vol.2
, pp. 357-362
-
-
Flotte, T.R.1
Carter, B.J.2
-
14
-
-
0029843596
-
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector
-
Xiao X, Li J, Samulski RJ. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. J Virol 1996; 70: 8098-8108. (Pubitemid 26339120)
-
(1996)
Journal of Virology
, vol.70
, Issue.11
, pp. 8098-8108
-
-
Xiao, X.1
Li, J.2
Samulski, R.J.3
-
15
-
-
0032051603
-
Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors
-
DOI 10.1006/exnr.1997.6736
-
Klein RL, Meyer EM, Peel AL, Zolotukhin S, Meyers C, Muzyczka N et al. Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombi-nant adeno-associated virus vectors. Exp Neurol 1998; 150: 183-194. (Pubitemid 28231949)
-
(1998)
Experimental Neurology
, vol.150
, Issue.2
, pp. 183-194
-
-
Klein, R.L.1
Meyer, E.M.2
Peel, A.L.3
Zolotukhin, S.4
Meyers, C.5
Muzyczka, N.6
King, M.A.7
-
16
-
-
34347327249
-
Adeno-associated viral delivery of a metabolically regulated insulin transgene to hepatocytes
-
DOI 10.1016/j.mce.2007.04.011, PII S030372070700161X
-
Kozlowski M, Olson DE, Rubin J, Lyszkowicz D, Campbell A, Thule PM. Adeno-associated viral delivery of a metabolically regulated insulin transgene to hepatocytes. Mol Cell Endocrinol 2007; 273: 6-15. (Pubitemid 47016742)
-
(2007)
Molecular and Cellular Endocrinology
, vol.273
, Issue.1-2
, pp. 6-15
-
-
Kozlowski, M.1
Olson, D.E.2
Rubin, J.3
Lyszkowicz, D.4
Campbell, A.5
Thule, P.M.6
-
17
-
-
0031011667
-
Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus
-
DOI 10.1073/pnas.94.13.6916
-
Flannery JG, Zolotukhin S, Vaquero MI, LaVail MM, Muzyczka N, Hauswirth WW. Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus. Proc Natl Acad Sci USA 1997; 94: 6916-6921. (Pubitemid 27281965)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.13
, pp. 6916-6921
-
-
Flannery, J.G.1
Zolotukhin, S.2
Vaquero, M.I.3
LaVail, M.M.4
Muzyczka, N.5
Hauswirth, W.W.6
-
18
-
-
39049165759
-
Suppression of lung tumor growth and metastasis in mice by adeno-associated virus-mediated expression of vasostatin
-
DOI 10.1158/1078-0432.CCR-07-1930
-
Cai KX, Tse LY, Leung C, Tam PK, Xu R, Sham MH. Suppression of lung tumor growth and metastasis in mice by adeno-associated virus-mediated expression of vasostatin. Clin Cancer Res 2008; 14: 939-949. (Pubitemid 351232942)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.3
, pp. 939-949
-
-
Ke, X.C.1
Lai, Y.T.2
Leung, C.3
Tam, P.K.H.4
Xu, R.5
Mai, H.S.6
-
19
-
-
41949111654
-
Gene delivery to intestinal epithelial cells in vitro and in vivo with recombinant adeno-associated virus types 1, 2 and 5
-
DOI 10.1007/s10620-007-9991-1
-
Polyak S, Mah C, Porvasnik S, Herlihy JD, Campbell-Thompson M, Byrne BJ et al. Gene delivery to intestinal epithelial cells in vitro and in vivo with recombinant adeno-associated virus types 1, 2 and 5. Dig Dis Sci 2008; 53: 1261-1270. (Pubitemid 351514644)
-
(2008)
Digestive Diseases and Sciences
, vol.53
, Issue.5
, pp. 1261-1270
-
-
Polyak, S.1
Mah, C.2
Porvasnik, S.3
Herlihy, J.-D.4
Campbell-Thompson, M.5
Byrne, B.J.6
Valentine, J.F.7
-
20
-
-
0348038748
-
Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo
-
DOI 10.1038/sj.gt.3302133
-
Wang Z, Ma HI, Li J, Sun L, Zhang J, Xiao X. Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo. Gene Therapy 2003; 10: 2105-2111. (Pubitemid 37536759)
-
(2003)
Gene Therapy
, vol.10
, Issue.26
, pp. 2105-2111
-
-
Wang, Z.1
Ma, H.-I.2
Li, J.3
Sun, L.4
Zhang, J.5
Xiao, X.6
-
21
-
-
33745322415
-
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes
-
DOI 10.1016/j.scitotenv.2006.03.040
-
Wang Z, Zhu T, Rehman KK, Bertera S, Zhang J, Chen C et al. Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. Diabetes 2006; 55: 875-884. (Pubitemid 44100159)
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 875-884
-
-
Wang, Z.1
Zhu, T.2
Rehman, K.K.3
Bertera, S.4
Zhang, J.5
Chen, C.6
Papworth, G.7
Watkins, S.8
Trucco, M.9
Robbins, P.D.10
Li, J.11
Xiao, X.12
-
22
-
-
0031936954
-
Glucagon-like peptides
-
Drucker DJ. Glucagon-like peptides. Diabetes 1998; 47: 159-169. (Pubitemid 28079969)
-
(1998)
Diabetes
, vol.47
, Issue.2
, pp. 159-169
-
-
Drucker, D.J.1
-
23
-
-
0033304603
-
The glucagon-like peptides
-
Kieffer TJ, Habener JF. The glucagon-like peptides. Endocr Rev 1999; 20: 876-913. (Pubitemid 30647076)
-
(1999)
Endocrine Reviews
, vol.20
, Issue.6
, pp. 876-913
-
-
Kieffer, T.J.1
Habener, J.F.2
-
24
-
-
70449699592
-
Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents
-
Arakawa M, Ebato C, Mita T, Hirose T, Kawamori R, Fujitani Y et al. Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents. Biochem Biophys Res Commun 2009; 390: 809-814.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 809-814
-
-
Arakawa, M.1
Ebato, C.2
Mita, T.3
Hirose, T.4
Kawamori, R.5
Fujitani, Y.6
-
25
-
-
70449701437
-
Exendin-4, a GLP-1 receptor agonist, directly induces adiponectin expression through protein kinase A pathway and prevents inflammatory adipokine expression
-
Kim Chung le T, Hosaka T, Yoshida M, Harada N, Sakaue H, Sakai T et al. Exendin-4, a GLP-1 receptor agonist, directly induces adiponectin expression through protein kinase A pathway and prevents inflammatory adipokine expression. Biochem Biophys Res Commun 2009; 390: 613-618.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 613-618
-
-
Kim Chung Le, T.1
Hosaka, T.2
Yoshida, M.3
Harada, N.4
Sakaue, H.5
Sakai, T.6
-
26
-
-
0026666235
-
Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini
-
Malhotra R, Singh L, Eng J, Raufman JP. Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini. Regul Pept 1992; 41: 149-156.
-
(1992)
Regul Pept
, vol.41
, pp. 149-156
-
-
Malhotra, R.1
Singh, L.2
Eng, J.3
Raufman, J.P.4
-
27
-
-
0027184119
-
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin- secreting β-cells
-
Goke R, Fehmann HC, Linn T, Schmidt H, Krause M, Eng J et al. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J Biol Chem 1993; 268: 19650-19655. (Pubitemid 23270754)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.26
, pp. 19650-19655
-
-
Goke, R.1
Fehmann, H.-C.2
Linn, T.3
Schmidt, H.4
Krause, M.5
Eng, J.6
Goke, B.7
-
28
-
-
15744381238
-
The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits β-cell apoptosis in vitro
-
DOI 10.1016/j.bbrc.2005.03.013
-
Bregenholt S, Moldrup A, Blume N, Karlsen AE, Nissen Friedrichsen B, Tornhave D et al. The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro. Biochem Biophys Res Commun 2005; 330: 577-584. (Pubitemid 40417684)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.330
, Issue.2
, pp. 577-584
-
-
Bregenholt, S.1
Moldrup, A.2
Blume, N.3
Karlsen, A.E.4
Friedrichsen, B.N.5
Tornhave, D.6
Knudsen, L.B.7
Petersen, J.S.8
-
29
-
-
33845975658
-
Gene therapy of diabetes using a novel GLP-1/IgG1-Fc fusion construct normalizes glucose levels in db/db mice
-
DOI 10.1038/sj.gt.3302836, PII 3302836
-
Kumar M, Hunag Y, Glinka Y, Prud'homme GJ, Wang Q. Gene therapy of diabetes using a novel GLP-1/IgG1-Fc fusion construct normalizes glucose levels in db/db mice. Gene Therapy 2007; 14: 162-172. (Pubitemid 46043821)
-
(2007)
Gene Therapy
, vol.14
, Issue.2
, pp. 162-172
-
-
Kumar, M.1
Hunag, Y.2
Glinka, Y.3
Prud'Homme, G.J.4
Wang, Q.5
-
30
-
-
33845655615
-
Ectopic expression of glucagon-like peptide 1 for gene therapy of type II diabetes
-
DOI 10.1038/sj.gt.3302842, PII 3302842
-
Parsons GB, Souza DW, Wu H, Yu D, Wadsworth SG, Gregory RJ et al. Ectopic expression of glucagon-like peptide 1 for gene therapy of type II diabetes. Gene Therapy 2007; 14: 38-48. (Pubitemid 44942864)
-
(2007)
Gene Therapy
, vol.14
, Issue.1
, pp. 38-48
-
-
Parsons, G.B.1
Souza, D.W.2
Wu, H.3
Yu, D.4
Wadsworth, S.G.5
Gregory, R.J.6
Armentano, D.7
-
31
-
-
34249741098
-
Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis
-
DOI 10.2337/db06-1182
-
Lee YS, Shin S, Shigihara T, Hahm E, Liu MJ, Han J et al. Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis. Diabetes 2007; 56: 1671-1679. (Pubitemid 46842602)
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1671-1679
-
-
Lee, Y.-S.1
Shin, S.2
Shigihara, T.3
Hahm, E.4
Liu, M.-J.5
Han, J.6
Yoon, J.-W.7
Jun, H.-S.8
-
32
-
-
40549086289
-
Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats
-
DOI 10.1002/jgm.1153
-
Lee Y, Kwon MK, Kang ES, Park YM, Choi SH, Ahn CW et al. Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats. J Gene Med 2008; 10: 260-268. (Pubitemid 351359638)
-
(2008)
Journal of Gene Medicine
, vol.10
, Issue.3
, pp. 260-268
-
-
Lee, Y.1
Kwon, M.-K.2
Kang, E.S.3
Park, Y.M.4
Choi, S.H.5
Ahn, C.W.6
Kim, K.S.7
Park, C.W.8
Cha, B.S.9
Kim, S.W.10
Sung, J.K.11
Lee, E.J.12
Lee, H.C.13
-
33
-
-
0028170362
-
Prospects for the use of adeno-associated virus as a vector for human gene therapy
-
Kotin RM. Prospects for the use of adeno-associated virus as a vector for human gene therapy. Hum Gene Ther 1994; 5: 793-801. (Pubitemid 24310566)
-
(1994)
Human Gene Therapy
, vol.5
, Issue.7
, pp. 793-801
-
-
Kotin, R.M.1
-
34
-
-
0029257496
-
The cryptic life style of adeno-associated virus
-
Berns KI, Linden RM. The cryptic life style of adeno-associated virus. Bioessays 1995; 17: 237-245.
-
(1995)
Bioessays
, vol.17
, pp. 237-245
-
-
Berns, K.I.1
Linden, R.M.2
-
35
-
-
0033761804
-
Adeno-associated virus vectors for gene therapy: More pros than cons?
-
Monahan PE, Samulski RJ. Adeno-associated virus vectors for gene therapy: more pros than cons? Mol Med Today 2000; 6: 433-440.
-
(2000)
Mol Med Today
, vol.6
, pp. 433-440
-
-
Monahan, P.E.1
Samulski, R.J.2
-
36
-
-
36749033228
-
The state of the art of adeno-associated virus-based vectors in gene therapy
-
Coura Rdos S, Nardi NB. The state of the art of adeno-associated virus-based vectors in gene therapy. Virol J 2007; 4: 99.
-
(2007)
Virol J
, vol.4
, pp. 99
-
-
Coura Rdos, S.1
Nardi, N.B.2
-
37
-
-
34247340606
-
Protection of pancreatic β-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies
-
DOI 10.1677/JOE-06-0148
-
Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh Y, Kaneko Y, Kimura T et al. Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies. J Endocrinol 2007; 193: 65-74. (Pubitemid 46638533)
-
(2007)
Journal of Endocrinology
, vol.193
, Issue.1
, pp. 65-74
-
-
Tsunekawa, S.1
Yamamoto, N.2
Tsukamoto, K.3
Itoh, Y.4
Kaneko, Y.5
Kimura, T.6
Ariyoshi, Y.7
Miura, Y.8
Oiso, Y.9
Niki, I.10
-
38
-
-
0029923638
-
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
-
Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol 1996; 70: 3227-3234. (Pubitemid 26121941)
-
(1996)
Journal of Virology
, vol.70
, Issue.5
, pp. 3227-3234
-
-
Ferrari, F.K.1
Samulski, T.2
Shenk, T.3
Samulski, R.J.4
-
39
-
-
0029655894
-
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis
-
Fisher KJ, Gao GP, Weitzman MD, DeMatteo R, Burda JF, Wilson JM. Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis. J Virol 1996; 70: 520-532. (Pubitemid 126508820)
-
(1996)
Journal of Virology
, vol.70
, Issue.1
, pp. 520-532
-
-
Fisher, K.J.1
Gao, G.-P.2
Weitzman, M.D.3
Dematteo, R.4
Burda, J.F.5
Wilson, J.M.6
-
40
-
-
0034882826
-
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis
-
DOI 10.1038/sj.gt.3301514
-
McCarty DM, Monahan PE, Samulski RJ. Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis. Gene Therapy 2001; 8: 1248-1254. (Pubitemid 32780813)
-
(2001)
Gene Therapy
, vol.8
, Issue.16
, pp. 1248-1254
-
-
McCarty, D.M.1
Monahan, P.E.2
Samulski, R.J.3
-
41
-
-
76749107401
-
DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes
-
Riedel MJ, Gaddy DF, Asadi A, Robbins PD, Kieffer TJ. DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes. Gene Therapy 2010; 17: 171-180.
-
(2010)
Gene Therapy
, vol.17
, pp. 171-180
-
-
Riedel, M.J.1
Gaddy, D.F.2
Asadi, A.3
Robbins, P.D.4
Kieffer, T.J.5
-
42
-
-
0346098008
-
Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo
-
DOI 10.1677/jme.0.0310529
-
Green BD, Gault VA, Mooney MH, Irwin N, Bailey CJ, Harriott P et al. Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo. J Mol Endocrinol 2003; 31: 529-540. (Pubitemid 38054523)
-
(2003)
Journal of Molecular Endocrinology
, vol.31
, Issue.3
, pp. 529-540
-
-
Green, B.D.1
Gault, V.A.2
Mooney, M.H.3
Irwin, N.4
Bailey, C.J.5
Harriott, P.6
Greer, B.7
Flatt, P.R.8
O'Harte, F.P.M.9
-
43
-
-
0026314334
-
Mammalian neural and endocrine pro-protein and pro-hormone convertases belonging to the subtilisin family of serine proteinases
-
Seidah NG, Day R, Marcinkiewicz M, Benjannet S, Chretien M. Mammalian neural and endocrine pro-protein and pro-hormone convertases belonging to the subtilisin family of serine proteinases. Enzyme 1991; 45: 271-284.
-
(1991)
Enzyme
, vol.45
, pp. 271-284
-
-
Seidah, N.G.1
Day, R.2
Marcinkiewicz, M.3
Benjannet, S.4
Chretien, M.5
-
44
-
-
0026775916
-
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
-
Molloy SS, Bresnahan PA, Leppla SH, Klimpel KR, Thomas G. Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem 1992; 267: 16396-16402.
-
(1992)
J Biol Chem
, vol.267
, pp. 16396-16402
-
-
Molloy, S.S.1
Bresnahan, P.A.2
Leppla, S.H.3
Klimpel, K.R.4
Thomas, G.5
-
45
-
-
0033551805
-
Quantitative characterization of furin specificity. Energetics of substrate discrimination using an internally consistent set of hexapeptidyl methylcoumarinamides
-
Krysan DJ, Rockwell NC, Fuller RS. Quantitative characterization of furin specificity. Energetics of substrate discrimination using an internally consistent set of hexapeptidyl methylcoumarinamides. J Biol Chem 1999; 274: 23229-23234.
-
(1999)
J Biol Chem
, vol.274
, pp. 23229-23234
-
-
Krysan, D.J.1
Rockwell, N.C.2
Fuller, R.S.3
-
46
-
-
0024448693
-
The genetics of diabetes susceptibility in mice
-
Leiter EH. The genetics of diabetes susceptibility in mice. FASEB J 1989; 3: 2231-2241. (Pubitemid 19229609)
-
(1989)
FASEB Journal
, vol.3
, Issue.11
, pp. 2231-2241
-
-
Leiter, E.H.1
-
48
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
DOI 10.1038/379069a0
-
Turton MD, O'Shea D, Gunn I, Beak SA, Edwards CM, Meeran K et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996; 379: 69-72. (Pubitemid 26008136)
-
(1996)
Nature
, vol.379
, Issue.6560
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
Beak, S.A.4
Edwards, C.M.B.5
Meeran, K.6
Choi, S.J.7
Taylor, G.M.8
Heath, M.M.9
Lambert, P.D.10
Wilding, J.P.H.11
Smith, D.M.12
Ghatei, M.A.13
Herbert, J.14
Bloom, S.R.15
-
49
-
-
33847617011
-
Mechanisms of action of glucagon-like peptide 1 in the pancreas
-
DOI 10.1016/j.pharmthera.2006.11.007, PII S0163725806002038
-
Doyle ME, Egan JM. Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacol Ther 2007; 113: 546-593. (Pubitemid 46365961)
-
(2007)
Pharmacology and Therapeutics
, vol.113
, Issue.3
, pp. 546-593
-
-
Doyle, M.E.1
Egan, J.M.2
-
50
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
DOI 10.1038/sj.cdd.4401373
-
Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004; 11: 381-389. (Pubitemid 38489416)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.4
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
51
-
-
0033541640
-
Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses
-
DOI 10.1089/10430349950018427
-
Clark KR, Liu X, McGrath JP, Johnson PR. Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses. Hum Gene Ther 1999; 10: 1031-1039. (Pubitemid 29195432)
-
(1999)
Human Gene Therapy
, vol.10
, Issue.6
, pp. 1031-1039
-
-
Clark, K.R.1
Liu, X.2
Mcgrath, J.P.3
Johnson, P.R.4
|