메뉴 건너뛰기




Volumn 47, Issue 4, 2011, Pages 520-529

MAPK and PI3K signalling differentially regulate angiogenic and lymphangiogenic cytokine secretion in squamous cell carcinoma of the head and neck

Author keywords

Epidermal growth factor receptor; Head and neck cancer; Lymphangiogenesis; Mitogen activated protein kinase; Phosphoinositide 3 kinase; Squamous cell carcinoma; Vascular endothelial growth factor A; Vascular endothelial growth factor C

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYTOKINE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; VASCULOTROPIN A; VASCULOTROPIN C;

EID: 79851515566     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.10.009     Document Type: Article
Times cited : (39)

References (48)
  • 1
    • 27144517452 scopus 로고    scopus 로고
    • Current clinical outcomes demand new treatment options for SCCHN
    • J.L. Lefebvre Current clinical outcomes demand new treatment options for SCCHN Ann Oncol 16 Suppl. 6 2005 vi7 vi12
    • (2005) Ann Oncol , vol.16 , Issue.SUPPL. 6
    • Lefebvre, J.L.1
  • 2
    • 62649157431 scopus 로고    scopus 로고
    • ErbB receptors in the biology and pathology of the aerodigestive tract
    • S. Morgan, and J.R. Grandis ErbB receptors in the biology and pathology of the aerodigestive tract Exp Cell Res 315 2009 572 582
    • (2009) Exp Cell Res , vol.315 , pp. 572-582
    • Morgan, S.1    Grandis, J.R.2
  • 3
    • 77954536872 scopus 로고    scopus 로고
    • How many nodes are needed to stage a neck? A critical appraisal
    • H.F. Kohler, and L.P. Kowalski How many nodes are needed to stage a neck? A critical appraisal Eur Arch Otorhinolaryngol 267 2010 785 791
    • (2010) Eur Arch Otorhinolaryngol , vol.267 , pp. 785-791
    • Kohler, H.F.1    Kowalski, L.P.2
  • 4
    • 70350348721 scopus 로고    scopus 로고
    • Nodal ratio as an independent predictor of survival in squamous cell carcinoma of the oral cavity
    • M.G. Shrime, G. Bachar, and J. Lea Nodal ratio as an independent predictor of survival in squamous cell carcinoma of the oral cavity Head Neck 31 2009 1482 1488
    • (2009) Head Neck , vol.31 , pp. 1482-1488
    • Shrime, M.G.1    Bachar, G.2    Lea, J.3
  • 6
    • 0036149083 scopus 로고    scopus 로고
    • C-erbB receptors in squamous cell carcinomas of the head and neck: Clinical significance and correlation with matrix metalloproteinases and vascular endothelial growth factors
    • DOI 10.1016/S1368-8375(01)00029-X, PII S136883750100029X
    • P. O-charoenrat, P.H. Rhys-Evans, D.J. Archer, and S.A. Eccles C-erbB receptors in squamous cell carcinomas of the head and neck: clinical significance and correlation with matrix metalloproteinases and vascular endothelial growth factors Oral Oncol 38 2002 73 80 (Pubitemid 34076575)
    • (2002) Oral Oncology , vol.38 , Issue.1 , pp. 73-80
    • O-charoenrat, P.1    Rhys-Evans, P.H.2    Archer, D.J.3    Eccles, S.A.4
  • 7
    • 0037115674 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
    • K.K. Ang, B.A. Berkey, and X. Tu Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma Cancer Res 62 2002 7350 7356 (Pubitemid 36025259)
    • (2002) Cancer Research , vol.62 , Issue.24 , pp. 7350-7356
    • Ang, K.K.1    Berkey, B.A.2    Tu, X.3    Zhang, H.-Z.4    Katz, R.5    Hammond, E.H.6    Fu, K.K.7    Milas, L.8
  • 8
    • 63749125392 scopus 로고    scopus 로고
    • VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
    • M. Lohela, M. Bry, T. Tammela, and K. Alitalo VEGFs and receptors involved in angiogenesis versus lymphangiogenesis Curr Opin Cell Biol 21 2009 154 165
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 154-165
    • Lohela, M.1    Bry, M.2    Tammela, T.3    Alitalo, K.4
  • 10
    • 58149088898 scopus 로고    scopus 로고
    • From anti-angiogenesis to anti-lymphangiogenesis: Emerging trends in cancer therapy
    • S.A. Stacker, and M.G. Achen From anti-angiogenesis to anti-lymphangiogenesis: emerging trends in cancer therapy Lymphat Res Biol 6 2008 165 172
    • (2008) Lymphat Res Biol , vol.6 , pp. 165-172
    • Stacker, S.A.1    Achen, M.G.2
  • 11
    • 4143135316 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer
    • DOI 10.1158/1078-0432.CCR-03-0434
    • Y. Zeng, K. Opeskin, and M.E. Baldwin Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer Clin Cancer Res 10 2004 5137 5144 (Pubitemid 39099788)
    • (2004) Clinical Cancer Research , vol.10 , Issue.15 , pp. 5137-5144
    • Zeng, Y.1    Opeskin, K.2    Baldwin, M.E.3    Horvath, L.G.4    Achen, M.G.5    Stacker, S.A.6    Sutherland, R.L.7    Williams, E.D.8
  • 12
    • 34047141776 scopus 로고    scopus 로고
    • Vascular endothelial growth factor family of ligands and receptors: Review
    • DOI 10.1016/j.bcmd.2006.12.003, PII S107997960700023X
    • Z.K. Otrock, J.A. Makarem, and A.I. Shamseddine Vascular endothelial growth factor family of ligands and receptors: review Blood Cells Mol Dis 38 2007 258 268 (Pubitemid 46518176)
    • (2007) Blood Cells, Molecules, and Diseases , vol.38 , Issue.3 , pp. 258-268
    • Otrock, Z.K.1    Makarem, J.A.2    Shamseddine, A.I.3
  • 13
    • 33947370773 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) signaling in tumor progression
    • DOI 10.1016/j.critrevonc.2007.01.006, PII S1040842807000182
    • R. Roskoski Jr. Vascular endothelial growth factor (VEGF) signaling in tumor progression Crit Rev Oncol Hematol 62 2007 179 213 (Pubitemid 46679285)
    • (2007) Critical Reviews in Oncology/Hematology , vol.62 , Issue.3 , pp. 179-213
    • Roskoski Jr., R.1
  • 14
    • 77249148863 scopus 로고    scopus 로고
    • Structural determinants of growth factor binding and specificity by VEGF receptor 2
    • V.M. Leppanen, A.E. Prota, and M. Jeltsch Structural determinants of growth factor binding and specificity by VEGF receptor 2 Proc Natl Acad Sci USA 107 2010 2425 2430
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2425-2430
    • Leppanen, V.M.1    Prota, A.E.2    Jeltsch, M.3
  • 15
    • 27744516670 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor-B (VEGF-B)
    • DOI 10.1016/j.pupt.2005.02.007, PII S1094553905000398, Molecular and Cellular Targets in Tissue Remodelling
    • A.D. Nash, M. Baca, C. Wright, and P.D. Scotney The biology of vascular endothelial growth factor-B (VEGF-B) Pulm Pharmacol Ther 19 2006 61 69 (Pubitemid 41606854)
    • (2006) Pulmonary Pharmacology and Therapeutics , vol.19 , Issue.1 , pp. 61-69
    • Nash, A.D.1    Baca, M.2    Wright, C.3    Scotney, P.D.4
  • 16
    • 70350445902 scopus 로고    scopus 로고
    • VEGF-B: A survival, or an angiogenic factor?
    • X. Li, C. Lee, and Z. Tang VEGF-B: a survival, or an angiogenic factor? Cell Adh Migr 3 2009 322 327
    • (2009) Cell Adh Migr , vol.3 , pp. 322-327
    • Li, X.1    Lee, C.2    Tang, Z.3
  • 17
    • 77955510391 scopus 로고    scopus 로고
    • VEGF-mediated signal transduction in lymphatic endothelial cells
    • F. Bahram, and L. Claesson-Welsh VEGF-mediated signal transduction in lymphatic endothelial cells Pathophysiology 17 2010 253 261
    • (2010) Pathophysiology , vol.17 , pp. 253-261
    • Bahram, F.1    Claesson-Welsh, L.2
  • 18
    • 77950675601 scopus 로고    scopus 로고
    • Targeting tumor lymphangiogenesis: An update
    • M. Raica, and D. Ribatti Targeting tumor lymphangiogenesis: an update Curr Med Chem 17 2010 698 708
    • (2010) Curr Med Chem , vol.17 , pp. 698-708
    • Raica, M.1    Ribatti, D.2
  • 20
    • 0035423906 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastasis
    • DOI 10.1002/1 097-0142(2001 0801)92:3<556 ::AID-CNC R1355>3.0.CO;2-Q
    • P. O-charoenrat, P. Rhys-Evans, and S.A. Eccles Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastasis Cancer 92 2001 556 568 (Pubitemid 32735191)
    • (2001) Cancer , vol.92 , Issue.3 , pp. 556-568
    • O-charoenrat, P.1    Rhys-Evans, P.2    Eccles, S.A.3
  • 21
    • 0037458645 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway
    • P.W. Tsai, S.G. Shiah, M.T. Lin, C.W. Wu, and M.L. Kuo Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway J Biol Chem 278 2003 5750 5759
    • (2003) J Biol Chem , vol.278 , pp. 5750-5759
    • Tsai, P.W.1    Shiah, S.G.2    Lin, M.T.3    Wu, C.W.4    Kuo, M.L.5
  • 22
    • 27644529696 scopus 로고    scopus 로고
    • Prognostic significance of VEGF immunohistochemical expression and tumor angiogenesis in head and neck squamous cell carcinoma
    • DOI 10.1007/s00432-005-0003-6
    • P.A. Kyzas, D. Stefanou, A. Batistatou, and N.J. Agnantis Prognostic significance of VEGF immunohistochemical expression and tumor angiogenesis in head and neck squamous cell carcinoma J Cancer Res Clin Oncol 131 2005 624 630 (Pubitemid 41558557)
    • (2005) Journal of Cancer Research and Clinical Oncology , vol.131 , Issue.9 , pp. 624-630
    • Kyzas, P.A.1    Stefanou, D.2    Batistatou, A.3    Agnantis, N.J.4
  • 24
    • 2942677282 scopus 로고    scopus 로고
    • Crosstalk between angiogenesis and lymphangiogenesis in tumor progression
    • DOI 10.1038/sj.leu.2403355
    • C. Scavelli, A. Vacca, G. Di Pietro, F. Dammacco, and D. Ribatti Crosstalk between angiogenesis and lymphangiogenesis in tumor progression Leukemia 18 2004 1054 1058 (Pubitemid 38786962)
    • (2004) Leukemia , vol.18 , Issue.6 , pp. 1054-1058
    • Scavelli, C.1    Vacca, A.2    Di Pietro, G.3    Dammacco, F.4    Ribatti, D.5
  • 26
    • 0035116241 scopus 로고    scopus 로고
    • Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells
    • DOI 10.1023/A:1006764100867
    • P. O-charoenrat, P. Rhys-Evans, H. Modjtahedi, and S.A. Eccles Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells Clin Exp Metastasis 18 2000 155 161 (Pubitemid 32165249)
    • (2000) Clinical and Experimental Metastasis , vol.18 , Issue.2 , pp. 155-161
    • O-charoenrat, P.1    Rhys-Evans, P.2    Modjtahedi, H.3    Eccles, S.4
  • 27
    • 59449092539 scopus 로고    scopus 로고
    • Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma
    • S. Guillard, P.A. Clarke, and R. Te Poele Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma Cell Cycle 8 2009 443 453
    • (2009) Cell Cycle , vol.8 , pp. 443-453
    • Guillard, S.1    Clarke, P.A.2    Te Poele, R.3
  • 29
    • 36549040859 scopus 로고    scopus 로고
    • The selectivity of protein kinase inhibitors: A further update
    • J. Bain, L. Plater, and M. Elliott The selectivity of protein kinase inhibitors: a further update Biochem J 408 2007 297 315
    • (2007) Biochem J , vol.408 , pp. 297-315
    • Bain, J.1    Plater, L.2    Elliott, M.3
  • 30
    • 0034652487 scopus 로고    scopus 로고
    • Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells
    • P. O-charoenrat, H. Modjtahedi, and P. Rhys-Evans Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells Cancer Res 60 2000 1121 1128 (Pubitemid 30129555)
    • (2000) Cancer Research , vol.60 , Issue.4 , pp. 1121-1128
    • O-Charoenrat, P.1    Modjtahedi, H.2    Rhys-Evans, P.3    Court, W.J.4    Box, G.M.5    Eccles, S.A.6
  • 31
    • 24044437159 scopus 로고    scopus 로고
    • Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): Possible link between angiogenesis and immune tolerance
    • L. Strauss, D. Volland, M. Kunkel, and T.E. Reichert Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): possible link between angiogenesis and immune tolerance Med Sci Monit 11 2005 BR280 BR292
    • (2005) Med Sci Monit , vol.11
    • Strauss, L.1    Volland, D.2    Kunkel, M.3    Reichert, T.E.4
  • 32
    • 0036605053 scopus 로고    scopus 로고
    • Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-κB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines
    • DOI 10.1002/ijc.10398
    • C.C. Bancroft, Z. Chen, and J. Yeh Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines Int J Cancer 99 2002 538 548 (Pubitemid 34461606)
    • (2002) International Journal of Cancer , vol.99 , Issue.4 , pp. 538-548
    • Bancroft, C.C.1    Chen, Z.2    Yeh, J.3    Sunwoo, J.B.4    Yeh, N.T.5    Jackson, S.6    Jackson, C.7    Van Waes, C.8
  • 33
    • 0035421326 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma
    • G. Dong, Z. Chen, and Z.Y. Li Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma Cancer Res 61 2001 5911 5918 (Pubitemid 32769111)
    • (2001) Cancer Research , vol.61 , Issue.15 , pp. 5911-5918
    • Dong, G.1    Chen, Z.2    Li, Z.-Y.3    Yeh, N.T.4    Bancroft, C.C.5    Van Waes, C.6
  • 36
    • 0035866387 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor in breast cancer cells by the heregulin-β1-activated p38 signaling pathway enhances endothelial cell migration
    • S. Xiong, R. Grijalva, and L. Zhang Up-regulation of vascular endothelial growth factor in breast cancer cells by the heregulin-beta1-activated p38 signaling pathway enhances endothelial cell migration Cancer Res 61 2001 1727 1732 (Pubitemid 34292611)
    • (2001) Cancer Research , vol.61 , Issue.4 , pp. 1727-1732
    • Xiong, S.1    Grijalva, R.2    Zhang, L.3    Nguyen, N.T.4    Pisters, P.W.5    Pollock, R.E.6    Yu, D.7
  • 37
    • 33646197026 scopus 로고    scopus 로고
    • Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways
    • Y. Liu, and B.M. Mueller Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways Biochem Biophys Res Commun 344 2006 1263 1270
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 1263-1270
    • Liu, Y.1    Mueller, B.M.2
  • 38
    • 0035677777 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is upregulated by interleukin-1β in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway
    • DOI 10.1023/A:1012291524723
    • Y.D. Jung, W. Liu, and N. Reinmuth Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway Angiogenesis 4 2001 155 162 (Pubitemid 34032701)
    • (2001) Angiogenesis , vol.4 , Issue.2 , pp. 155-162
    • Jung, Y.D.1    Liu, W.2    Reinmuth, N.3    Ahmad, S.A.4    Fan, F.5    Gallick, G.E.6    Ellis, L.M.7
  • 39
    • 0036228789 scopus 로고    scopus 로고
    • Hypoxic induction of HIF-1α and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases
    • DOI 10.1016/S1368-8375(01)00052-5, PII S1368837501000525
    • B. Shemirani, and D.L. Crowe Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases Oral Oncol 38 2002 251 257 (Pubitemid 34442546)
    • (2002) Oral Oncology , vol.38 , Issue.3 , pp. 251-257
    • Shemirani, B.1    Crowe, D.L.2
  • 40
    • 34147121375 scopus 로고    scopus 로고
    • Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis
    • DOI 10.1111/j.1349-7006.2007.00439.x
    • S. Kobayashi, T. Kishimoto, and S. Kamata Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis Cancer Sci 98 2007 726 733 (Pubitemid 46563450)
    • (2007) Cancer Science , vol.98 , Issue.5 , pp. 726-733
    • Kobayashi, S.1    Kishimoto, T.2    Kamata, S.3    Otsuka, M.4    Miyazaki, M.5    Ishikura, H.6
  • 41
    • 0037444268 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor
    • Y. Tang, D. Zhang, L. Fallavollita, and P. Brodt Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor Cancer Res 63 2003 1166 1171 (Pubitemid 36348689)
    • (2003) Cancer Research , vol.63 , Issue.6 , pp. 1166-1171
    • Tang, Y.1    Zhang, D.2    Fallavollita, L.3    Brodt, P.4
  • 42
    • 2642641324 scopus 로고    scopus 로고
    • Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C
    • DOI 10.1074/jbc.273.14.8413
    • A. Ristimaki, K. Narko, B. Enholm, V. Joukov, and K. Alitalo Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C J Biol Chem 273 1998 8413 8418 (Pubitemid 28168903)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.14 , pp. 8413-8418
    • Ristimaki, A.1    Narko, K.2    Enholm, B.3    Joukov, V.4    Alitalo, K.5
  • 44
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • D. Shweiki, A. Itin, D. Soffer, and E. Keshet Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis Nature 359 1992 843 845
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 45
    • 34547134517 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif
    • DOI 10.1074/jbc.M611782200
    • S.C. Land, and A.R. Tee Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif J Biol Chem 282 2007 20534 20543 (Pubitemid 47100043)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20534-20543
    • Land, S.C.1    Tee, A.R.2
  • 46
    • 77349127052 scopus 로고    scopus 로고
    • The Akt expression correlates with the VEGF-A and -C expression as well as the microvessel and lymphatic vessel density in breast cancer
    • S. Tsutsui, A. Matsuyama, and M. Yamamoto The Akt expression correlates with the VEGF-A and -C expression as well as the microvessel and lymphatic vessel density in breast cancer Oncol Rep 23 2010 621 630
    • (2010) Oncol Rep , vol.23 , pp. 621-630
    • Tsutsui, S.1    Matsuyama, A.2    Yamamoto, M.3
  • 48
    • 41049091680 scopus 로고    scopus 로고
    • Tumor lymphangiogenesis and lymphangiogenic growth factors
    • M.X. Da, Z. Wu, and H.W. Tian Tumor lymphangiogenesis and lymphangiogenic growth factors Arch Med Res 39 2008 365 372
    • (2008) Arch Med Res , vol.39 , pp. 365-372
    • Da, M.X.1    Wu, Z.2    Tian, H.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.