VEGF-A, VEGF-C, and VEGF-D in colorectal cancer progression

Neoplasia

Volumn 3, Issue 5, 2001, Pages 420-427

  George, Mark L ^a,b   Tutton, Matthew G ^a,b   Janssen, Frank ^b   Arnaoutz, Abed ^a   Abulafi, A Muti ^a   Eccles, Suzanne A ^b   Swift, R Ian ^a  

^a MAYDAY UNIVERSITY HOSPITAL   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Adenoma carcinoma; Angiogenesis; Immunohistochemistry; Lymphatic; Staging

Indexed keywords

MESSENGER RNA; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

ADENOMATOUS POLYP; ANGIOGENESIS; ARTICLE; CANCER GROWTH; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034769958     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.neo.7900186     Document Type: Article

References (43)

1. What is the evidence that tumors are angiogenesis-dependent?
2. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
3. Localization of the human vascular endothelial growth factor gene, VEGF, at chromosome 6p12
4. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
5. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
6. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
7. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
8. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
9. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
10. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
11. Expression of angiogenesis stimulators and inhibitors in human thyroid tumors and correlation with clinical pathological features
12. Vascular endothelial growth factor-C expression in human prostatic carcinoma and its relationship to lymph node metastasis
13. Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer
14. Expression of vascular endothelial growth factors A, B, C, and D and their relationships to lymph node status in lung adenocarcinoma
15. Molecular cloning of a novel vascular endothelial growth factor, VEGF-D
16. Vascular endothelial growth factor C induces angiogenesis in vivo
17. c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro
18. Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C
19. VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
20. Vascular endothelial growth factors VEGF-B and VEGF-C are expressed in human tumors
21. Vascular endothelial growth factor-C gene expression in papillary and follicular thyroid carcinomas
22. High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas
23. Vegf, vegf-B, vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa
24. Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues
25. The short form of the alternatively spliced flt-4 but not its ligand vascular endothelial growth factor C is related to lymph node metastasis in human breast cancers
26. VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumors
27. Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastases
28. Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: Clinical evidence of platelet scavenging?
29. VEGFc and VEGFR3 expression in human thyroid pathologies
30. Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis
31. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
32. Vascular endothelial growth factor-C and its receptor VEGFR-3 in the nasal mucosa and in nasopharyngeal tumors
33. Absence of functional lymphatics within a murine sarcoma: A molecular and functional evaluation
34. Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer
35. Involvement of vascular endothelial growth factor and urokinase-type plasminogen activator receptor in microvessel invasion in human colorectal cancers
36. Vascular endothelial growth factor is up-regulated in the early premalignant stage of colorectal tumour progression
37. Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer
38. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
39. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract
40. Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients
41. Expression of vascular endothelial growth factor can predict event-free survival in stage II colon cancer
42. Microvessel density and VEGF expression in human tumours of different localisation
43. VEGF expression correlates with haematogenous metastasis and prognosis in colorectal carcinoma