Nodal ratio as an independent predictor of survival in squamous cell carcinoma of the oral cavity

Head and Neck

Volumn 31, Issue 11, 2009, Pages 1482-1488

  Shrime, Mark G ^a   Bachar, Gideon ^b   Lea, Jane ^a   Volling, Cheryl ^c   Ma, Clement ^a   Gullane, Patrick J ^a   Gilbert, Ralph W ^a   Irish, Jonathan C ^a   Brown, Dale H ^a   Goldstein, David P ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b RABIN MEDICAL CENTER   (Israel)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Neck dissection; Nodal density; Nodal ratio; Oral cavity; Squamous cell carcinoma

Indexed keywords

ADULT; ARTICLE; CANCER SURVIVAL; CLINICAL ASSESSMENT; DISEASE FREE SURVIVAL; DISEASE PREDISPOSITION; FEMALE; HIGH RISK POPULATION; HUMAN; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; MOUTH CARCINOMA; OVERALL SURVIVAL; PREDICTOR VARIABLE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPH NODES; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NECK DISSECTION; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SURVIVAL RATE; YOUNG ADULT;

EID: 70350348721     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.21114     Document Type: Article

References (40)

1. Funk GF, Karnell LH, Robinson RA, Zhen WK, Trask DK, Hoffman HT. Presentation, treatment, and outcome of oral cavity cancer: a National Cancer Database report. Head Neck 2002;24:165-180.
2. Ries LAG, Melbert D, Krapcho M, et al. SEER Cancer Statistics Review, 1975-2005. In; 2008.
3. Cooper JS, Pajak TF, Forastiere AA, et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004;350:1937-1944.
4. Day TA, Davis BK, Gillespie MB, et al. Oral cancer treatment. Curr Treat Options Oncol 2003;4:27-41.
5. Grecula JC, Schuller DE, Rhoades CA, et al. Intensification regimen 2 for advanced head and neck squamous cell carcinomas. Arch Otolaryngol Head Neck Surg 1999;125:1313-1318.
6. Clark JR, Naranjo N, Franklin JH, de Almeida J, Gullane PJ. Established prognostic variables in N0 oral carcinoma. Otolaryngol Head Neck Surg 2006;135:748-753. (Pubitemid 44634875)
7. Bando E, Yonemura Y, Taniguchi K, Fushida S, Fujimura T, Miwa K. Outcome of ratio of lymph node metastasis in gastric carcinoma. Ann Surg Oncol 2002;9:775-784.
8. 0 colorectal cancer. Hepatogastroenterology 2004;51:1689-1693.
9. Berger AC, Sigurdson ER, LeVoyer T, et al. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol 2005;23:8706-8712. (Pubitemid 46211514)
10. Chan JK, Kapp DS, Cheung MK, et al. The impact of the absolute number and ratio of positive lymph nodes on survival of endometrioid uterine cancer patients. Br J Cancer 2007;97:605-611.
11. Chen SL, Bilchik AJ. More extensive nodal dissection improves survival for stages I to III of colon cancer: a population-based study. Ann Surg 2006;244:602-610.
12. Cianchi F, Palomba A, Boddi V, et al. Lymph node recovery from colorectal tumor specimens: recommendation for a minimum number of lymph nodes to be examined. World J Surg 2002;26:384-389. (Pubitemid 36920420)
13. Joseph NE, Sigurdson ER, Hanlon A, et al. Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol 2003;10:213-218. (Pubitemid 40486952)
14. LeVoyer T, Sigurdson ER, Hanlon A, et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol 2003;21:2912-2919. (Pubitemid 46621841)
15. Mammen JM, James LE, Molloy M, Williams A, Wray CJ, Sussman JJ. The relationship of lymph node dissection and colon cancer survival in the Veterans Affairs Central Cancer Registry. Am J Surg 2007;194:349-354. (Pubitemid 47212037)
16. Sierzega M, Popiela T, Kulig J, Nowak K. The ratio of metastatic/resected lymph nodes is an independent prognostic factor with node-positive pancreatic-head cancer. Pancreas 2006;33:240-245. (Pubitemid 44470138)
17. Shrime MG, Ma CS, Gullane PJ, et al. The impact of nodal ratio on survival in squamous cell carcinoma of the oral cavity. Head Neck 2009; Epub ahead of print.
18. Lausen B, Schumacher M. Maximally selected rank statistics. Biometrics 1992;48:73-85.
19. Capote A, Escorial V, Munoz-Guerra MF, Rodriguez-Camp FJ, Gamallo C, Naval L. Elective neck dissection in early-stage squamous cell carcinoma-does it influence recurrence and survival? Head Neck 2007;29:3-11.
20. Koo BS, Lim YC, Lee JS, Choi EC. Management of contralateral N0 neck in oral cavity squamous cell carcinoma. Head Neck 2006;28:896-901. (Pubitemid 44497865)
21. Agrama MT, Reiter D, Cunnane MF, Topham A, Keane WM. Nodal yield in neck dissection and the likelihood of metastases. Otolaryngol Head Neck Surg 2003;128:185-190. (Pubitemid 36314865)
22. 3 colorectal resection specimens spanning 45 years: recommendations for a minimum number of recovered lymph nodes based on predictive probabilities. Am J Surg Pathol 2002;26:179-189.
23. Herr HW, Bochner BH, Dalbagni G, Donat SM, Reuter VE, Bajorin DF. Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer. J Urol 2002;167:1295-1298. (Pubitemid 34132073)
24. Tepper JE, O'Connell MJ, Niedzwiecki D, et al. Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol 2001;19:157-163. (Pubitemid 32063492)
25. Vinh-Hung V, Verschraegen C, Promish DI, et al. Ratios of involved nodes in early breast cancer. Breast Cancer Res 2004;6:R680-R688.
26. Weir L, Speers C, D'Yachkova Y, Olivotto IA. Prognostic significance of the number of axillary lymph nodes removed in patients with node-negative breast cancer. J Clin Oncol 2002;20:1793-1799. (Pubitemid 34273268)
27. Woodward WA, Vinh-Hung V, Ueno NT, et al. Prognostic value of nodal ratios in node-positive breast cancer. J Clin Oncol 2006;24:2910-2916. (Pubitemid 46630594)
28. Compton C, Fielding LP, Burgart LJ, et al. Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000;124:979-994.
29. Goldstein NS, Sanford W, Coffey M, Layfield LJ. Lymph node recovery from colorectal resection specimens removed for adenocarcinoma. Trends over time and a recommendation for a minimum number of lymph nodes to be recovered. Am J Clin Pathol 1996;106:209-216. (Pubitemid 26277211)
30. Marchet A, Mocellin S, Ambrosi A, et al. The prognostic value of N-ratio in patients with gastric cancer: validation in a large, multicenter series. Eur J Surg Oncol 2008;34:159-165.
31. Maurel J, Launoy G, Grosclaude P, et al. Lymph node harvest reporting in patients with carcinoma of the large bowel: a French population-based study. Cancer 1998;82:1482-1486. (Pubitemid 28164993)
32. Scott KW, Grace RH. Detection of lymph node metastasis in colorectal carcinoma before and after fat clearance. Br J Surg 1989;76:1165-1167. (Pubitemid 19284443)
33. 0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol 2003;10:65-71.
34. Tang X, Tanemura K, Ye W, et al. Clinicopathological factors predicting retroperitoneal lymph node metastasis and survival in endometrial cancer. Jpn J Clin Oncol 1998;28:673-678. (Pubitemid 128523210)
35. Wong JH, Severino R, Honnebier MB, Tom P, Namiki TS. Number of nodes examined and staging accuracy in colorectal carcinoma. J Clin Oncol 1999;17:2896-2900. (Pubitemid 29415250)
36. Yasunaga M, Yamasaki F, Tokunaga O, Iwasaka T. Endometrial carcinomas with lymph node involvement: novel histologic factors for predicting prognosis. Int J Gynecol Pathol 2003;22:341-346. (Pubitemid 37152982)
37. Ang KK, Trotti A, Brown BW, et al. Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 2001;51:571-578. (Pubitemid 32946890)
38. Akaike H. A new look at the statistical model identification. IEEE Trans Automatic Control 1974;19:716-723.
39. Elsheikh MN, Mahfouz ME, Elsheikh E. Level IIb lymph node metastasis in elective supraomohyoid neck dissection for oral cavity squamous cell carcinoma: a molecular-based study. Laryngoscope 2005;2005:9. (Pubitemid 41330676)
40. Lim YC, Song MH, Kim SC, Kim KM, Choi EC. Preserving level IIb lymph nodes in elective supraomohyoid neck dissection for oral cavity squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2004;130:1088-1091. (Pubitemid 39195392)