A specific inhibitor of protein kinase CK2 delays gamma-H2Ax foci removal and reduces clonogenic survival of irradiated mammalian cells

Radiation Oncology

Volumn 6, Issue 1, 2011, Pages

  Zwicker, Felix ^a,b   Ebert, Maren ^a   Huber, Peter E ^a,b   Debus, Jürgen ^a   Weber, Klaus Josef ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; 4,5,6,7 TETRABROMOBENZOTRIAZOLE; CASEIN KINASE II; DNA FRAGMENT; HISTONE H2AX; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG; 4,5,6,7-TETRABROMOBENZOTRIAZOLE; H2AFX PROTEIN, HUMAN; HISTONE; PROTEIN KINASE INHIBITOR; TRIAZOLE DERIVATIVE;

APOPTOSIS; ARTICLE; CELL KILLING; CELL LINE; CELL SURVIVAL; CLONOGENIC ASSAY; COLON CARCINOMA; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; DNA STRAND BREAKAGE; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IRRADIATION; MAMMAL CELL; PULSED FIELD GEL ELECTROPHORESIS; RADIOSENSITIZATION; STAINING; ANIMAL; CANCER STEM CELL; CELL CULTURE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; ENZYME SPECIFICITY; GENETICS; MAMMAL; METABOLISM; PATHOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; TIME;

ANIMALS; CASEIN KINASE II; CELL SURVIVAL; CELLS, CULTURED; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DRUG EVALUATION, PRECLINICAL; FIBROBLASTS; HISTONES; HUMANS; MAMMALS; NEOPLASTIC STEM CELLS; PROTEIN KINASE INHIBITORS; SUBSTRATE SPECIFICITY; TIME FACTORS; TRIAZOLES; TUMOR STEM CELL ASSAY;

EID: 79751528817     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-6-15     Document Type: Article

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