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Volumn 25, Issue 2, 2011, Pages 277-283

Liquiritigenin induces mitochondria-mediated apoptosis via cytochrome c release and caspases activation in heLa cells

Author keywords

apoptosis; caspase; cytochrome c; liquiritigenin; p53; PARP

Indexed keywords

CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; LIQUIRITIGENIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SURVIVIN;

EID: 79551669602     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3259     Document Type: Article
Times cited : (38)

References (39)
  • 1
    • 0642317016 scopus 로고    scopus 로고
    • Survivin in apoptosis control and cell cycle regulation in cancer
    • Altieri DC,. 2003. Survivin in apoptosis control and cell cycle regulation in cancer. Prog Cell Cycle Res 5: 447-452.
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 447-452
    • Altieri, D.C.1
  • 3
    • 0036087028 scopus 로고    scopus 로고
    • Role of Bcl-2 family of proteins in malignancy
    • Baliga BC, Kumar S,. 2002. Role of Bcl-2 family of proteins in malignancy. Hematol Oncol 20: 63-74.
    • (2002) Hematol Oncol , vol.20 , pp. 63-74
    • Baliga, B.C.1    Kumar, S.2
  • 4
    • 45849145772 scopus 로고    scopus 로고
    • Protoapigenone, a novel flavonoid, inhibits ovarian cancer cell growth in vitro and in vivo
    • Chang HL, Su JH, Yeh YT, et al. 2008. Protoapigenone, a novel flavonoid, inhibits ovarian cancer cell growth in vitro and in vivo. Cancer Lett 267: 85-95.
    • (2008) Cancer Lett , vol.267 , pp. 85-95
    • Chang, H.L.1    Su, J.H.2    Yeh, Y.T.3
  • 5
    • 16644403653 scopus 로고    scopus 로고
    • Flavone inhibition of tumor growth via apoptosis in vitro and in vivo
    • Chen YC, Shen SC, Chow JM, Ko CH, Tseng SW,. 2004. Flavone inhibition of tumor growth via apoptosis in vitro and in vivo. Int J Oncol 3: 661-670.
    • (2004) Int J Oncol , vol.3 , pp. 661-670
    • Chen, Y.C.1    Shen, S.C.2    Chow, J.M.3    Ko, C.H.4    Tseng, S.W.5
  • 6
    • 33646828739 scopus 로고    scopus 로고
    • Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells
    • Chiang LC, Ng LT, Lin IC, Kuo PL, Lin CC,. 2006. Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells. Cancer Lett 237: 207-214.
    • (2006) Cancer Lett , vol.237 , pp. 207-214
    • Chiang, L.C.1    Ng, L.T.2    Lin, I.C.3    Kuo, P.L.4    Lin, C.C.5
  • 7
    • 57349119001 scopus 로고    scopus 로고
    • Equol induces apoptosis through cytochrome c-mediated caspases cascade in human breast cancer MDA-MB-453 cells
    • Choi EJ, Ahn WS, Baea SM,. 2009. Equol induces apoptosis through cytochrome c-mediated caspases cascade in human breast cancer MDA-MB-453 cells. Chem Biol Interact 177: 7-11.
    • (2009) Chem Biol Interact , vol.177 , pp. 7-11
    • Choi, E.J.1    Ahn, W.S.2    Baea, S.M.3
  • 8
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ,. 2004. Cell death: critical control points. Cell 116: 205-219.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 9
    • 2342453921 scopus 로고    scopus 로고
    • Death receptors in chemotherapy and cancer
    • Debatin KM, Krammer PH,. 2004. Death receptors in chemotherapy and cancer. Oncogene 23: 2950-2966.
    • (2004) Oncogene , vol.23 , pp. 2950-2966
    • Debatin, K.M.1    Krammer, P.H.2
  • 10
    • 9644278114 scopus 로고    scopus 로고
    • Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis
    • Dohi T, Beltrami E, Wall NR, Plescin J, Altieri DC,. 2004. Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis. J Clin Invest 114: 1117-1127.
    • (2004) J Clin Invest , vol.114 , pp. 1117-1127
    • Dohi, T.1    Beltrami, E.2    Wall, N.R.3    Plescin, J.4    Altieri, D.C.5
  • 11
    • 0037178573 scopus 로고    scopus 로고
    • Dietary intake of antioxidants and risk of Alzheimer disease
    • Engelhart MJ, Geerlings MI, Ruitenberg A, et al. 2002. Dietary intake of antioxidants and risk of Alzheimer disease. JAMA 287: 3223-3229.
    • (2002) JAMA , vol.287 , pp. 3223-3229
    • Engelhart, M.J.1    Geerlings, M.I.2    Ruitenberg, A.3
  • 12
    • 17444415708 scopus 로고    scopus 로고
    • Cytotoxic flavonoids from Platymiscium floribundum
    • Falcão MJ, Pouliquem YB, Lima MA, et al. 2005. Cytotoxic flavonoids from Platymiscium floribundum. J Nat Prod 68: 423-426.
    • (2005) J Nat Prod , vol.68 , pp. 423-426
    • Falcão, M.J.1    Pouliquem, Y.B.2    Lima, M.A.3
  • 13
    • 33746895175 scopus 로고    scopus 로고
    • Mitochondria as therapeutic targets for cancer chemotherapy
    • Galluzzi L, Larochette N, Zamzami N, Kroemer G,. 2006. Mitochondria as therapeutic targets for cancer chemotherapy. Oncogene 25: 4812-4830.
    • (2006) Oncogene , vol.25 , pp. 4812-4830
    • Galluzzi, L.1    Larochette, N.2    Zamzami, N.3    Kroemer, G.4
  • 15
    • 2442460060 scopus 로고    scopus 로고
    • Inhibitory effect of genistein and daidzein on ovarian cancer cell growth
    • Gercel-Taylor C, Feitelson AK, Taylor DD,. 2004. Inhibitory effect of genistein and daidzein on ovarian cancer cell growth. Anticancer Res 24: 795-800.
    • (2004) Anticancer Res , vol.24 , pp. 795-800
    • Gercel-Taylor, C.1    Feitelson, A.K.2    Taylor, D.D.3
  • 16
    • 33645330122 scopus 로고    scopus 로고
    • Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro
    • Hedlund TE, van Bokhoven A, Johannes WU, Nordeen SK, Ogden LG,. 2006. Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro. Prostate 66: 557-566.
    • (2006) Prostate , vol.66 , pp. 557-566
    • Hedlund, T.E.1    Van Bokhoven, A.2    Johannes, W.U.3    Nordeen, S.K.4    Ogden, L.G.5
  • 17
    • 0036479115 scopus 로고    scopus 로고
    • Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
    • Hoffman WH, Biade S, Zilfou JT, Chen J, Murphy M,. 2002. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 277: 3247-3257.
    • (2002) J Biol Chem , vol.277 , pp. 3247-3257
    • Hoffman, W.H.1    Biade, S.2    Zilfou, J.T.3    Chen, J.4    Murphy, M.5
  • 18
    • 67349242722 scopus 로고    scopus 로고
    • Induction of apoptosis in human hepatocarcinoma SMMC-7721 cells in vitro by flavonoids from Astragalus complanatus
    • Hu YW, Liu CY, Du CM, Zhang J, Wu WQ, Gu ZL,. 2009. Induction of apoptosis in human hepatocarcinoma SMMC-7721 cells in vitro by flavonoids from Astragalus complanatus. J Ethnopharmacol 123: 293-301.
    • (2009) J Ethnopharmacol , vol.123 , pp. 293-301
    • Hu, Y.W.1    Liu, C.Y.2    Du, C.M.3    Zhang, J.4    Wu, W.Q.5    Gu, Z.L.6
  • 20
    • 9644260590 scopus 로고    scopus 로고
    • Survivin: A bifunctional inhibitor of apoptosis protein
    • Johnson ME, Howerth EW,. 2004. Survivin: a bifunctional inhibitor of apoptosis protein. Vet Pathol 41: 599-607.
    • (2004) Vet Pathol , vol.41 , pp. 599-607
    • Johnson, M.E.1    Howerth, E.W.2
  • 21
    • 39149132456 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis
    • Kalra N, Roy P, Prasad S, Shukla Y,. 2008. Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis. Life Sci 82: 348-358.
    • (2008) Life Sci , vol.82 , pp. 348-358
    • Kalra, N.1    Roy, P.2    Prasad, S.3    Shukla, Y.4
  • 22
    • 33646850088 scopus 로고    scopus 로고
    • Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine
    • Kim YW, Ki SH, Lee JR, et al. 2006. Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine. Chem Biol Interact 161: 125-138.
    • (2006) Chem Biol Interact , vol.161 , pp. 125-138
    • Kim, Y.W.1    Ki, S.H.2    Lee, J.R.3
  • 23
    • 42949164997 scopus 로고    scopus 로고
    • Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-Î?B-dependent iNOS and proinflammatory cytokines production
    • Kim YW, Zhao RJ, Park SJ, et al. 2008. Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-Î?B-dependent iNOS and proinflammatory cytokines production. Br J Pharmacol 154: 165-173.
    • (2008) Br J Pharmacol , vol.154 , pp. 165-173
    • Kim, Y.W.1    Zhao, R.J.2    Park, S.J.3
  • 24
    • 34249987420 scopus 로고    scopus 로고
    • Caspase-independent death of human osteosarcoma cells by flavonoids is driven by p53-mediated mitochondrial stress and nuclear translocation of AIF and endonuclease G
    • Kook SH, Son YO, Chung SW, et al. 2007. Caspase-independent death of human osteosarcoma cells by flavonoids is driven by p53-mediated mitochondrial stress and nuclear translocation of AIF and endonuclease G. Apoptosis 12: 1289-1298.
    • (2007) Apoptosis , vol.12 , pp. 1289-1298
    • Kook, S.H.1    Son, Y.O.2    Chung, S.W.3
  • 25
    • 33845480548 scopus 로고    scopus 로고
    • Caspase function in programmed cell death
    • Kumar S,. 2007. Caspase function in programmed cell death. Cell Death Differ 14: 32-43.
    • (2007) Cell Death Differ , vol.14 , pp. 32-43
    • Kumar, S.1
  • 26
  • 27
    • 39149111920 scopus 로고    scopus 로고
    • Liquiritigenin is a plant-derived highly selective estrogen receptor β-agonist
    • Mersereau JE, Levy N, Staub RE, et al. 2008. Liquiritigenin is a plant-derived highly selective estrogen receptor β-agonist. Mol Cell Endocrinol 283: 49-57.
    • (2008) Mol Cell Endocrinol , vol.283 , pp. 49-57
    • Mersereau, J.E.1    Levy, N.2    Staub, R.E.3
  • 28
    • 33748788835 scopus 로고    scopus 로고
    • Molecular mechanism of 'mitocan'-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins
    • Neuzil J, Wang XF, Dong LF, Low P, Ralph SJ,. 2006. Molecular mechanism of 'mitocan'-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins. FEBS Lett 580: 5125-5129.
    • (2006) FEBS Lett , vol.580 , pp. 5125-5129
    • Neuzil, J.1    Wang, X.F.2    Dong, L.F.3    Low, P.4    Ralph, S.J.5
  • 29
    • 13244289838 scopus 로고    scopus 로고
    • Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species
    • Pan MH, Lai CS, Hsu PC, Wang YJ,. 2005. Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species. J Agric Food Chem 53: 620-630.
    • (2005) J Agric Food Chem , vol.53 , pp. 620-630
    • Pan, M.H.1    Lai, C.S.2    Hsu, P.C.3    Wang, Y.J.4
  • 30
    • 34248226610 scopus 로고    scopus 로고
    • Apigenin and cancer chemoprevention: Progress, potential and promise (Review)
    • Patel D, Shukla S, Gupta S,. 2007. Apigenin and cancer chemoprevention: Progress, potential and promise (Review). Int J Oncol 30: 233-245.
    • (2007) Int J Oncol , vol.30 , pp. 233-245
    • Patel, D.1    Shukla, S.2    Gupta, S.3
  • 31
    • 34249882770 scopus 로고    scopus 로고
    • Effects of dietary flavonoids on apoptotic pathways related to cancer chemoprevention
    • Ramos S,. 2007. Effects of dietary flavonoids on apoptotic pathways related to cancer chemoprevention. J Nutr Biochem 18: 427-442.
    • (2007) J Nutr Biochem , vol.18 , pp. 427-442
    • Ramos, S.1
  • 32
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: Bioavailability, metabolic effects, and safety
    • Ross JA, Kasum CM,. 2002. Dietary flavonoids: bioavailability, metabolic effects, and safety. Ann Rev Nutr 22: 19-34.
    • (2002) Ann Rev Nutr , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 34
    • 0037427412 scopus 로고    scopus 로고
    • Mechanisms of cytochrome c release by proapoptotic Bcl-2 family members
    • Scorrano L, Koresmeyer SJ,. 2003. Mechanisms of cytochrome c release by proapoptotic Bcl-2 family members. Biochem Biophys Res Commun 304: 437-444.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 437-444
    • Scorrano, L.1    Koresmeyer, S.J.2
  • 35
    • 31544448040 scopus 로고    scopus 로고
    • Daidzein-sulfate metabolites affect transcriptional and antiproliferative activities of estrogen receptor-beta in cultured human cancer cells
    • Totta P, Acconcia F, Virgili F, et al. 2005. Daidzein-sulfate metabolites affect transcriptional and antiproliferative activities of estrogen receptor-beta in cultured human cancer cells. J Nutr 135: 2687-2693.
    • (2005) J Nutr , vol.135 , pp. 2687-2693
    • Totta, P.1    Acconcia, F.2    Virgili, F.3
  • 37
    • 60849112240 scopus 로고    scopus 로고
    • Effect of liquiritigenin, a flavanone existed from Radix glycyrrhizae on pro-apoptotic in SMMC-7721 cells
    • Zhang SP, Zhou YJ, Liu Y, Cai YQ,. 2009. Effect of liquiritigenin, a flavanone existed from Radix glycyrrhizae on pro-apoptotic in SMMC-7721 cells. Food Chem Toxicol 47: 693-701.
    • (2009) Food Chem Toxicol , vol.47 , pp. 693-701
    • Zhang, S.P.1    Zhou, Y.J.2    Liu, Y.3    Cai, Y.Q.4
  • 38
    • 79551673421 scopus 로고    scopus 로고
    • Experimental study on the in vivo antitumor effect of the total flavonoids from radix glycyrrhizae
    • Zhao SY, Nong ZX, Zhong ZG,. 2006. Experimental study on the in vivo antitumor effect of the total flavonoids from radix glycyrrhizae. Guangxi Med J 28: 1348-1350.
    • (2006) Guangxi Med J , vol.28 , pp. 1348-1350
    • Zhao, S.Y.1    Nong, Z.X.2    Zhong, Z.G.3
  • 39
    • 77953243584 scopus 로고    scopus 로고
    • Inhibition of hepatoma 22 tumor by liquiritigenin
    • Zhou M, Higo H, Cai Y,. 2010. Inhibition of hepatoma 22 tumor by liquiritigenin. Phytother Res 24: 827-833.
    • (2010) Phytother Res , vol.24 , pp. 827-833
    • Zhou, M.1    Higo, H.2    Cai, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.