Induction of apoptosis in human hepatocarcinoma SMMC-7721 cells in vitro by flavonoids from Astragalus complanatus

Journal of Ethnopharmacology

Volumn 123, Issue 2, 2009, Pages 293-301

  Hu, Yan Wei ^a   Liu, Chun Yu ^a   Du, Chong Min ^a   Zhang, Jian ^a   Wu, Wen Qian ^a   Gu, Zhen Lun ^b  

^a SOOCHOW UNIVERSITY   (China)

^b Suzhou Institute of Chinese Materia Medica   (China)

Author keywords

Apoptosis; Astragalus complanatus; Caspases; Cell cycle; Flavonoids; Microarray

Indexed keywords

ASTRAGALUS COMPLANATUS EXTRACT; ASTRAGALUS EXTRACT; CASPASE 3; CASPASE 8; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 4; DNA; FLAVONOID; PROTEIN BAX; PROTEIN P21; PROTEIN P27; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; ASTRAGALUS PLANT; CARCINOMA CELL; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DEATH; CELL STRAIN HEPG2; CELL VIABILITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA CONTENT; DNA FRAGMENTATION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; MICROARRAY ANALYSIS; REGULATOR GENE; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ASTRAGALUS PLANT; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DNA FRAGMENTATION; FLAVONOIDS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SEEDS;

ASTRAGALUS COMPLANATUS;

EID: 67349242722     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.03.016     Document Type: Article

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