-
2
-
-
4344575903
-
Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease
-
Austin RC, Lentz SR, and Werstuck GH. Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death Differ 11(suppl 1): S56-S64, 2004.
-
(2004)
Cell Death Differ
, vol.11
, Issue.SUPPL. 1
-
-
Austin, R.C.1
Lentz, S.R.2
Werstuck, G.H.3
-
3
-
-
17644373797
-
Oxidative protein folding: An update
-
Benham A. Oxidative protein folding: an update. Antioxid Redox Signal 7: 835-838, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 835-838
-
-
Benham, A.1
-
4
-
-
0036877142
-
The endoplasmic reticulum: A multifunctional signaling organelle
-
Berridge MJ. The endoplasmic reticulum: a multifunctional signaling organelle. Cell Calcium 32: 235-249, 2002.
-
(2002)
Cell Calcium
, vol.32
, pp. 235-249
-
-
Berridge, M.J.1
-
5
-
-
0041534405
-
Calcium dynamics and endoplasmic reticular function in the regulation of protein synthesis: Implications for cell growth and adaptability
-
Brostrom MA and Brostrom CO. Calcium dynamics and endoplasmic reticular function in the regulation of protein synthesis: implications for cell growth and adaptability. Cell Calcium 34: 345-363, 2003.
-
(2003)
Cell Calcium
, vol.34
, pp. 345-363
-
-
Brostrom, M.A.1
Brostrom, C.O.2
-
6
-
-
0033979568
-
Critical evaluation of ECV304 as a human endothelial cell model defined by genetic analysis and functional responses: A comparison with the human bladder cancer derived epithelial cell line T24/83
-
Brown J, Reading SJ, Jones S, Fitchett CJ, Howl J, Martin A, Longland CL, Michelangeli F, Dubrova YE, and Brown CA. Critical evaluation of ECV304 as a human endothelial cell model defined by genetic analysis and functional responses: a comparison with the human bladder cancer derived epithelial cell line T24/83. Lab Invest 80: 37-45, 2000.
-
(2000)
Lab Invest
, vol.80
, pp. 37-45
-
-
Brown, J.1
Reading, S.J.2
Jones, S.3
Fitchett, C.J.4
Howl, J.5
Martin, A.6
Longland, C.L.7
Michelangeli, F.8
Dubrova, Y.E.9
Brown, C.A.10
-
7
-
-
1942505974
-
Effects of taurine and homocysteine on calcium homeostasis and hydrogen peroxide and superoxide anions in rat myocardial mitochondria
-
Chang L, Zhao J, Xu J, Jiang W, Tang CS, and Qi YF. Effects of taurine and homocysteine on calcium homeostasis and hydrogen peroxide and superoxide anions in rat myocardial mitochondria. Clin Exp Pharmacol Physiol 31: 237-243, 2004.
-
(2004)
Clin Exp Pharmacol Physiol
, vol.31
, pp. 237-243
-
-
Chang, L.1
Zhao, J.2
Xu, J.3
Jiang, W.4
Tang, C.S.5
Qi, Y.F.6
-
8
-
-
1542685624
-
Regulation of cytosolic free calcium concentration in cultured renal epithelial cells
-
Cheung JY, Constantine JM, and Bonventre JV. Regulation of cytosolic free calcium concentration in cultured renal epithelial cells. Am J Physiol 251: F690-F701, 1986.
-
(1986)
Am J Physiol
, vol.251
-
-
Cheung, J.Y.1
Constantine, J.M.2
Bonventre, J.V.3
-
9
-
-
0025756673
-
Hyperhomocysteinemia: An independent risk factor for vascular disease
-
Clarke R, Daly L, Robinson K, Naughten E, Cahalane S, Fowler B, and Graham I. Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med 324: 1149-1155, 1991.
-
(1991)
N Engl J Med
, vol.324
, pp. 1149-1155
-
-
Clarke, R.1
Daly, L.2
Robinson, K.3
Naughten, E.4
Cahalane, S.5
Fowler, B.6
Graham, I.7
-
10
-
-
33644790277
-
Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: Implications in atherogenesis
-
Dickhout JG, Hossain GS, Pozza LM, Zhou J, Lhotak S, and Austin RC. Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler Thromb Vasc Biol 25: 2623-2629, 2005.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2623-2629
-
-
Dickhout, J.G.1
Hossain, G.S.2
Pozza, L.M.3
Zhou, J.4
Lhotak, S.5
Austin, R.C.6
-
11
-
-
0037144663
-
Tubulovascular nitric oxide crosstalk: Buffering of angiotensin II-induced medullary vasoconstriction
-
Dickhout JG, Mori T, and Cowley AW Jr. Tubulovascular nitric oxide crosstalk: buffering of angiotensin II-induced medullary vasoconstriction. Circ Res 91: 487-493, 2002.
-
(2002)
Circ Res
, vol.91
, pp. 487-493
-
-
Dickhout, J.G.1
Mori, T.2
Cowley Jr., A.W.3
-
12
-
-
0013969948
-
Preparation of L-homocysteine from L-homocysteine thiolactone
-
Duerre JA and Miller CH. Preparation of L-homocysteine from L-homocysteine thiolactone. Anal Biochem 17: 310-315, 1966.
-
(1966)
Anal Biochem
, vol.17
, pp. 310-315
-
-
Duerre, J.A.1
Miller, C.H.2
-
13
-
-
33750902737
-
The endoplasmic reticulum: Folding, calcium homeostasis, signaling, and redox control
-
Gorlach A, Klappa P, and Kietzmann T. The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control. Antioxid Redox Signal 8: 1391-1418, 2006.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1391-1418
-
-
Gorlach, A.1
Klappa, P.2
Kietzmann, T.3
-
14
-
-
18144404121
-
Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation
-
Handy DE, Zhang Y, and Loscalzo J. Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation. J Biol Chem 280: 15518-15525, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 15518-15525
-
-
Handy, D.E.1
Zhang, Y.2
Loscalzo, J.3
-
15
-
-
0041989674
-
TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia
-
Hossain GS, van Thienen JV, Werstuck GH, Zhou J, Sood SK, Dickhout JG, de Koning AB, Tang D, Wu D, Falk E, Poddar R, Jacobsen DW, Zhang K, Kaufman RJ, and Austin RC. TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia. J Biol Chem 278: 30317-30327, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 30317-30327
-
-
Hossain, G.S.1
van Thienen, J.V.2
Werstuck, G.H.3
Zhou, J.4
Sood, S.K.5
Dickhout, J.G.6
de Koning, A.B.7
Tang, D.8
Wu, D.9
Falk, E.10
Poddar, R.11
Jacobsen, D.W.12
Zhang, K.13
Kaufman, R.J.14
Austin, R.C.15
-
16
-
-
3242797419
-
Activation of mesangial cell MAPK in response to homocysteine
-
Ingram AJ, Krepinsky JC, James L, Austin RC, Tang D, Salapatek AM, Thai K, and Scholey JW. Activation of mesangial cell MAPK in response to homocysteine. Kidney Int 66: 733-745, 2004.
-
(2004)
Kidney Int
, vol.66
, pp. 733-745
-
-
Ingram, A.J.1
Krepinsky, J.C.2
James, L.3
Austin, R.C.4
Tang, D.5
Salapatek, A.M.6
Thai, K.7
Scholey, J.W.8
-
17
-
-
0344306690
-
Homocysteine-thiolactone and S-nitroso-homocysteine mediate incorporation of homocysteine into protein in humans
-
Jakubowski H. Homocysteine-thiolactone and S-nitroso-homocysteine mediate incorporation of homocysteine into protein in humans. Clin Chem Lab Med 41: 1462-1466, 2003.
-
(2003)
Clin Chem Lab Med
, vol.41
, pp. 1462-1466
-
-
Jakubowski, H.1
-
19
-
-
0033562966
-
Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
-
Kaufman RJ. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 13: 1211-1233, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 1211-1233
-
-
Kaufman, R.J.1
-
20
-
-
0016241906
-
Tunicamycin: An inhibitor of yeast glycoprotein synthesis
-
Kuo SC and Lampen JO. Tunicamycin: an inhibitor of yeast glycoprotein synthesis. Biochem Biophys Res Commun 58: 287-295, 1974.
-
(1974)
Biochem Biophys Res Commun
, vol.58
, pp. 287-295
-
-
Kuo, S.C.1
Lampen, J.O.2
-
21
-
-
0035423875
-
The glucose-regulated proteins: Stress induction and clinical applications
-
Lee AS. The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci 26: 504-510, 2001.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 504-510
-
-
Lee, A.S.1
-
22
-
-
0033826673
-
Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice
-
Lentz SR, Erger RA, Dayal S, Maeda N, Malinow MR, Heistad DD, and Faraci FM. Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice. Am J Physiol Heart Circ Physiol 279: H970-H975, 2000.
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.279
-
-
Lentz, S.R.1
Erger, R.A.2
Dayal, S.3
Maeda, N.4
Malinow, M.R.5
Heistad, D.D.6
Faraci, F.M.7
-
23
-
-
0027472128
-
Homocysteine inhibits von Willebrand factor processing and secretion by preventing transport from the endoplasmic reticulum
-
Lentz SR and Sadler JE. Homocysteine inhibits von Willebrand factor processing and secretion by preventing transport from the endoplasmic reticulum. Blood 81: 683-689, 1993.
-
(1993)
Blood
, vol.81
, pp. 683-689
-
-
Lentz, S.R.1
Sadler, J.E.2
-
24
-
-
0026345948
-
Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
-
Lentz SR and Sadler JE. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. J Clin Invest 88: 1906-1914, 1991.
-
(1991)
J Clin Invest
, vol.88
, pp. 1906-1914
-
-
Lentz, S.R.1
Sadler, J.E.2
-
25
-
-
0029939676
-
Homocysteine and vascular disease
-
McCully KS. Homocysteine and vascular disease. Nat Med 2: 386-389, 1996.
-
(1996)
Nat Med
, vol.2
, pp. 386-389
-
-
McCully, K.S.1
-
26
-
-
33645457949
-
Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway
-
Moshal KS, Sen U, Tyagi N, Henderson B, Steed M, Ovechkin AV, and Tyagi SC. Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway. Am J Physiol Cell Physiol 290: C883-C891, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Moshal, K.S.1
Sen, U.2
Tyagi, N.3
Henderson, B.4
Steed, M.5
Ovechkin, A.V.6
Tyagi, S.C.7
-
27
-
-
0021894152
-
The natural history of homocystinuria due to cystathionine beta-synthase deficiency
-
Mudd SH, Skovby F, Levy HL, Pettigrew KD, Wilcken B, Pyeritz RE, Andria G, Boers GH, Bromberg IL, Cerone R, Fowler B, Gröbe H, Schmidt H, and Schweitzer L. The natural history of homocystinuria due to cystathionine beta-synthase deficiency. Am J Hum Genet 37: 1-31, 1985.
-
(1985)
Am J Hum Genet
, vol.37
, pp. 1-31
-
-
Mudd, S.H.1
Skovby, F.2
Levy, H.L.3
Pettigrew, K.D.4
Wilcken, B.5
Pyeritz, R.E.6
Andria, G.7
Boers, G.H.8
Bromberg, I.L.9
Cerone, R.10
Fowler, B.11
Gröbe, H.12
Schmidt, H.13
Schweitzer, L.14
-
28
-
-
0034009713
-
Homocyst(e)ine induces calcium second messenger in vascular smooth muscle cells
-
Mujumdar VS, Hayden MR, and Tyagi SC. Homocyst(e)ine induces calcium second messenger in vascular smooth muscle cells. J Cell Physiol 183: 28-36, 2000.
-
(2000)
J Cell Physiol
, vol.183
, pp. 28-36
-
-
Mujumdar, V.S.1
Hayden, M.R.2
Tyagi, S.C.3
-
29
-
-
0032524586
-
Characterization of the stress-inducing effects of homocysteine
-
Outinen PA, Sood SK, Liaw PC, Sarge KD, Maeda N, Hirsh J, Ribau J, Podor TJ, Weitz JI, and Austin RC. Characterization of the stress-inducing effects of homocysteine. Biochem J 332: 213-221, 1998.
-
(1998)
Biochem J
, vol.332
, pp. 213-221
-
-
Outinen, P.A.1
Sood, S.K.2
Liaw, P.C.3
Sarge, K.D.4
Maeda, N.5
Hirsh, J.6
Ribau, J.7
Podor, T.J.8
Weitz, J.I.9
Austin, R.C.10
-
30
-
-
0345535616
-
Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells
-
Outinen PA, Sood SK, Pfeifer SI, Pamidi S, Podor TJ, Li J, Weitz JI, and Austin RC. Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells. Blood 94: 959-967, 1999.
-
(1999)
Blood
, vol.94
, pp. 959-967
-
-
Outinen, P.A.1
Sood, S.K.2
Pfeifer, S.I.3
Pamidi, S.4
Podor, T.J.5
Li, J.6
Weitz, J.I.7
Austin, R.C.8
-
31
-
-
0043037253
-
Endoplasmic reticulum: A primary target in various acute disorders and degenerative diseases of the brain
-
Paschen W. Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell Calcium 34: 365-383, 2003.
-
(2003)
Cell Calcium
, vol.34
, pp. 365-383
-
-
Paschen, W.1
-
32
-
-
0034930141
-
Mechanisms of capacitative calcium entry
-
Putney JW Jr, Broad LM, Braun FJ, Lievremont JP, and Bird GS. Mechanisms of capacitative calcium entry. J Cell Sci 114: 2223-2229, 2001.
-
(2001)
J Cell Sci
, vol.114
, pp. 2223-2229
-
-
Putney Jr, J.W.1
Broad, L.M.2
Braun, F.J.3
Lievremont, J.P.4
Bird, G.S.5
-
33
-
-
1842843860
-
Coupling endoplasmic reticulum stress to the cell death program
-
Rao RV, Ellerby HM, and Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 11: 372-380, 2004.
-
(2004)
Cell Death Differ
, vol.11
, pp. 372-380
-
-
Rao, R.V.1
Ellerby, H.M.2
Bredesen, D.E.3
-
34
-
-
15944374827
-
-
Stojilkovic SS. Ca2-regulated exocytosis and SNARE function. Trends Endocrinol Metab 16: 81-83, 2005.
-
Stojilkovic SS. Ca2-regulated exocytosis and SNARE function. Trends Endocrinol Metab 16: 81-83, 2005.
-
-
-
-
35
-
-
0037930861
-
Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity
-
Watson LM, Chan AK, Berry LR, Li J, Sood SK, Dickhout JG, Xu L, Werstuck GH, Bajzar L, Klamut HJ, and Austin RC. Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity. J Biol Chem 278: 17438-17447, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 17438-17447
-
-
Watson, L.M.1
Chan, A.K.2
Berry, L.R.3
Li, J.4
Sood, S.K.5
Dickhout, J.G.6
Xu, L.7
Werstuck, G.H.8
Bajzar, L.9
Klamut, H.J.10
Austin, R.C.11
-
36
-
-
0035014266
-
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
-
Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, Zhou J, Maeda N, Krisans SK, Malinow MR, and Austin RC. Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 107: 1263-1273, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 1263-1273
-
-
Werstuck, G.H.1
Lentz, S.R.2
Dayal, S.3
Hossain, G.S.4
Sood, S.K.5
Shi, Y.Y.6
Zhou, J.7
Maeda, N.8
Krisans, S.K.9
Malinow, M.R.10
Austin, R.C.11
-
37
-
-
0035570015
-
Vascular outcome in patients with homocystinuria due to cystathionine beta-synthase deficiency treated chronically: A multicenter observational study
-
Yap S, Boers GH, Wilcken B, Wilcken DE, Brenton DP, Lee PJ, Walter JH, Howard PM, and Naughten ER. Vascular outcome in patients with homocystinuria due to cystathionine beta-synthase deficiency treated chronically: a multicenter observational study. Arterioscler Thromb Vasc Biol 21: 2080-2085, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 2080-2085
-
-
Yap, S.1
Boers, G.H.2
Wilcken, B.3
Wilcken, D.E.4
Brenton, D.P.5
Lee, P.J.6
Walter, J.H.7
Howard, P.M.8
Naughten, E.R.9
-
39
-
-
14244254669
-
Homocysteine inhibits store-mediated calcium entry in human endothelial cells: Evidence for involvement of membrane potential and actin cytoskeleton
-
Zhang HS, Xiao JH, Cao EH, and Qin JF. Homocysteine inhibits store-mediated calcium entry in human endothelial cells: evidence for involvement of membrane potential and actin cytoskeleton. Mol Cell Biochem 269: 37-47, 2005.
-
(2005)
Mol Cell Biochem
, vol.269
, pp. 37-47
-
-
Zhang, H.S.1
Xiao, J.H.2
Cao, E.H.3
Qin, J.F.4
-
40
-
-
3142772088
-
Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice
-
Zhou J, Werstuck GH, Lhotak S, de Koning AB, Sood SK, Hossain GS, Moller J, Ritskes-Hoitinga M, Falk E, Dayal S, Lentz SR, and Austin RC. Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice. Circulation 110: 207-213, 2004.
-
(2004)
Circulation
, vol.110
, pp. 207-213
-
-
Zhou, J.1
Werstuck, G.H.2
Lhotak, S.3
de Koning, A.B.4
Sood, S.K.5
Hossain, G.S.6
Moller, J.7
Ritskes-Hoitinga, M.8
Falk, E.9
Dayal, S.10
Lentz, S.R.11
Austin, R.C.12
-
41
-
-
33645845744
-
Excitotoxic neuronal injury in acute homocysteine neurotoxicity: Role of calcium and mitochondrial alterations
-
Zieminska E, Matyja E, Kozlowska H, Stafiej A, and Lazarewicz JW. Excitotoxic neuronal injury in acute homocysteine neurotoxicity: role of calcium and mitochondrial alterations. Neurochem Int 48: 491-497, 2006.
-
(2006)
Neurochem Int
, vol.48
, pp. 491-497
-
-
Zieminska, E.1
Matyja, E.2
Kozlowska, H.3
Stafiej, A.4
Lazarewicz, J.W.5
|