메뉴 건너뛰기




Volumn 49, Issue 3, 2011, Pages 550-555

Unraveling the mechanism of β-N-oxalyl-α,β-diaminopropionic acid (β-ODAP) induced excitotoxicity and oxidative stress, relevance for neurolathyrism prevention

Author keywords

ODAP; Calcium; Excitotoxicity; Oxidative stress

Indexed keywords

3 OXALYLAMINOALANINE; CYSTEINE; GLUTAMATE TRANSPORTER; METHIONINE; REACTIVE OXYGEN METABOLITE;

EID: 79551607849     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.03.054     Document Type: Article
Times cited : (32)

References (64)
  • 1
    • 0028859087 scopus 로고
    • Molecular detection of methionine in rat brain using specific antibodies
    • Amara A., Coussemacq M., Geffard M. Molecular detection of methionine in rat brain using specific antibodies. Neurosci. Lett. 1995, 185(3):147-150.
    • (1995) Neurosci. Lett. , vol.185 , Issue.3 , pp. 147-150
    • Amara, A.1    Coussemacq, M.2    Geffard, M.3
  • 2
    • 0025954497 scopus 로고
    • Gliotoxic properties of the Lathyrus excitotoxin β-N-oxalyl-l-α,β-diaminopropionic acid (β-L-ODAP)
    • Bridges R.J., Hatalski C., Shim S.N., Nunn P.B. Gliotoxic properties of the Lathyrus excitotoxin β-N-oxalyl-l-α,β-diaminopropionic acid (β-L-ODAP). Brain Res. 1991, 561(2):262-268.
    • (1991) Brain Res. , vol.561 , Issue.2 , pp. 262-268
    • Bridges, R.J.1    Hatalski, C.2    Shim, S.N.3    Nunn, P.B.4
  • 3
    • 0023818943 scopus 로고
    • Inhibition of [3H]α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding by the excitotoxin β-N-oxalyl-l-α,β-diaminopropionic acid
    • Bridges R.J., Kadri M.M., Monaghan D.T., Nunn P.B., Watkins J.C., Cotman C.W. Inhibition of [3H]α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding by the excitotoxin β-N-oxalyl-l-α,β-diaminopropionic acid. Eur. J. Pharmacol. 1988, 145(3):357-359.
    • (1988) Eur. J. Pharmacol. , vol.145 , Issue.3 , pp. 357-359
    • Bridges, R.J.1    Kadri, M.M.2    Monaghan, D.T.3    Nunn, P.B.4    Watkins, J.C.5    Cotman, C.W.6
  • 4
    • 0024334022 scopus 로고
    • Structure-function studies on N-oxalyl-diamino-dicarboxylic acids and excitatory amino acid receptors: evidence that β-L-ODAP is a selective non-NMDA agonist
    • Bridges R.J., Stevens D.R., Kahle J.S., Nunn P.B., Kadri M., Cotman C.W. Structure-function studies on N-oxalyl-diamino-dicarboxylic acids and excitatory amino acid receptors: evidence that β-L-ODAP is a selective non-NMDA agonist. J. Neurosci. 1989, 9(6):2073-2079.
    • (1989) J. Neurosci. , vol.9 , Issue.6 , pp. 2073-2079
    • Bridges, R.J.1    Stevens, D.R.2    Kahle, J.S.3    Nunn, P.B.4    Kadri, M.5    Cotman, C.W.6
  • 5
    • 0036313059 scopus 로고    scopus 로고
    • Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane
    • Brustovetsky N., Brustovetsky T., Jemmerson R., Dubinsky J.M. Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane. J. Neurochem. 2002, 80(2):207-218.
    • (2002) J. Neurochem. , vol.80 , Issue.2 , pp. 207-218
    • Brustovetsky, N.1    Brustovetsky, T.2    Jemmerson, R.3    Dubinsky, J.M.4
  • 6
    • 0030015076 scopus 로고    scopus 로고
    • Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro
    • Carriedo S.G., Yin H.Z., Weiss J.H. Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro. J. Neurosci. 1996, 16(13):4069-4079.
    • (1996) J. Neurosci. , vol.16 , Issue.13 , pp. 4069-4079
    • Carriedo, S.G.1    Yin, H.Z.2    Weiss, J.H.3
  • 7
    • 0035008127 scopus 로고    scopus 로고
    • Excitotoxicity of Lathyrus sativus neurotoxin in leech retzius neurons
    • Cemerikic D., Nedeljkov V., Lopicic S., Dragovic S., Beleslin B. Excitotoxicity of Lathyrus sativus neurotoxin in leech retzius neurons. Physiol. Res. 2001, 50(2):205-214.
    • (2001) Physiol. Res. , vol.50 , Issue.2 , pp. 205-214
    • Cemerikic, D.1    Nedeljkov, V.2    Lopicic, S.3    Dragovic, S.4    Beleslin, B.5
  • 8
    • 34047131622 scopus 로고    scopus 로고
    • 2+ determine motoneuron vulnerability in rat spinal cord in vivo
    • 2+ determine motoneuron vulnerability in rat spinal cord in vivo. Neuropharmacology 2007, 52(5):1219-1228.
    • (2007) Neuropharmacology , vol.52 , Issue.5 , pp. 1219-1228
    • Corona, J.C.1    Tapia, R.2
  • 9
    • 68649116755 scopus 로고    scopus 로고
    • SR/ER-mitochondrial local communication: calcium and ROS
    • Csordas G., Hajnoczky G. SR/ER-mitochondrial local communication: calcium and ROS. Biochim. Biophys. Acta 2009, 1787(11):1352-1362.
    • (2009) Biochim. Biophys. Acta , vol.1787 , Issue.11 , pp. 1352-1362
    • Csordas, G.1    Hajnoczky, G.2
  • 10
    • 0024263111 scopus 로고
    • Effects of Ca2+ on the activities of the calcium-sensitive dehydrogenases within the mitochondria of mammalian tissues. J. Cardiovasc. Pharmacol.
    • Denton, R.M., Rutter, G.A., Midgley, P.J., McCormack, J.G., 1988. Effects of Ca2+ on the activities of the calcium-sensitive dehydrogenases within the mitochondria of mammalian tissues. J. Cardiovasc. Pharmacol. 12 Suppl. 5: S69-72.
    • (1988) , vol.12 , Issue.SUPPL. 5 , pp. 69-72
    • Denton, R.M.1    Rutter, G.A.2    Midgley, P.J.3    McCormack, J.G.4
  • 11
    • 44049099669 scopus 로고    scopus 로고
    • Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
    • Devi L., Raghavendran V., Prabhu B.M., Avadhani N.G., Anandatheerthavarada H.K. Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J. Biol. Chem. 2008, 283(14):9089-9100.
    • (2008) J. Biol. Chem. , vol.283 , Issue.14 , pp. 9089-9100
    • Devi, L.1    Raghavendran, V.2    Prabhu, B.M.3    Avadhani, N.G.4    Anandatheerthavarada, H.K.5
  • 12
    • 33845188132 scopus 로고    scopus 로고
    • Down-regulation of glutaredoxin by estrogen receptor antagonist renders female mice susceptible to excitatory amino acid mediated complex I inhibition in CNS
    • Diwakar L., Kenchappa R.S., Annepu J., Saeed U., Sujanitha R., Ravindranath V. Down-regulation of glutaredoxin by estrogen receptor antagonist renders female mice susceptible to excitatory amino acid mediated complex I inhibition in CNS. Brain Res. 2006, 1125(1):176-184.
    • (2006) Brain Res. , vol.1125 , Issue.1 , pp. 176-184
    • Diwakar, L.1    Kenchappa, R.S.2    Annepu, J.3    Saeed, U.4    Sujanitha, R.5    Ravindranath, V.6
  • 13
    • 33846308476 scopus 로고    scopus 로고
    • Inhibition of cystathionine-gamma-lyase leads to loss of glutathione and aggravation of mitochondrial dysfunction mediated by excitatory amino acid in the CNS
    • Diwakar L., Ravindranath V. Inhibition of cystathionine-gamma-lyase leads to loss of glutathione and aggravation of mitochondrial dysfunction mediated by excitatory amino acid in the CNS. Neurochem. Int. 2007, 50(2):418-426.
    • (2007) Neurochem. Int. , vol.50 , Issue.2 , pp. 418-426
    • Diwakar, L.1    Ravindranath, V.2
  • 14
    • 0032967382 scopus 로고    scopus 로고
    • The role of excitotoxicity in neurodegenerative disease: implications for therapy
    • Doble A. The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol. Ther. 1999, 81(3):163-221.
    • (1999) Pharmacol. Ther. , vol.81 , Issue.3 , pp. 163-221
    • Doble, A.1
  • 15
    • 0028819581 scopus 로고
    • Parvalbumin Is a Marker of Als-Resistant Motor-Neurons
    • Elliott J.L., Snider W.D. Parvalbumin Is a Marker of Als-Resistant Motor-Neurons. Neuroreport 1995, 6(3):449-452.
    • (1995) Neuroreport , vol.6 , Issue.3 , pp. 449-452
    • Elliott, J.L.1    Snider, W.D.2
  • 16
    • 72149102424 scopus 로고    scopus 로고
    • Effect of methionine supplement on physical responses and neurological symptoms in broiler chicks fed grass pea (Lathyrus sativus)-based starter ration
    • Fikre A., Yami A., Kuo Y.H., Ahmed S., Gheysen G., Lambein F. Effect of methionine supplement on physical responses and neurological symptoms in broiler chicks fed grass pea (Lathyrus sativus)-based starter ration. Food Chem. Toxicol. 2010, 48:11-17.
    • (2010) Food Chem. Toxicol. , vol.48 , pp. 11-17
    • Fikre, A.1    Yami, A.2    Kuo, Y.H.3    Ahmed, S.4    Gheysen, G.5    Lambein, F.6
  • 17
    • 0024971817 scopus 로고
    • BOAA selectively enhances l-glutamate release from guinea pig hippocampal mossy fiber synaptosomes
    • Gannon R.L., Terrian D.M. BOAA selectively enhances l-glutamate release from guinea pig hippocampal mossy fiber synaptosomes. Neurosci. Lett. 1989, 107(1-3):289-294.
    • (1989) Neurosci. Lett. , vol.107 , Issue.1-3 , pp. 289-294
    • Gannon, R.L.1    Terrian, D.M.2
  • 18
    • 0345118223 scopus 로고    scopus 로고
    • ABO blood groups, grass pea preparation, and neurolathyrism in Ethiopia
    • Getahun H., Lambein F., Van der Stuyft P. ABO blood groups, grass pea preparation, and neurolathyrism in Ethiopia. Trans. R Soc. Trop. Med. Hyg. 2002, 96(6):700-703.
    • (2002) Trans. R Soc. Trop. Med. Hyg. , vol.96 , Issue.6 , pp. 700-703
    • Getahun, H.1    Lambein, F.2    Van der Stuyft, P.3
  • 19
    • 0344688187 scopus 로고    scopus 로고
    • Food-aid cereals to reduce neurolathyrism related to grass-pea preparations during famine
    • Getahun H., Lambein F., Vanhoorne M., Van der Stuyft P. Food-aid cereals to reduce neurolathyrism related to grass-pea preparations during famine. Lancet 2003, 362(9398):1808-1810.
    • (2003) Lancet , vol.362 , Issue.9398 , pp. 1808-1810
    • Getahun, H.1    Lambein, F.2    Vanhoorne, M.3    Van der Stuyft, P.4
  • 20
    • 13944263638 scopus 로고    scopus 로고
    • Neurolathyrism risk depends on type of grass pea preparation and on mixing with cereals and antioxidants
    • Getahun H., Lambein F., Vanhoorne M., Van der Stuyft P. Neurolathyrism risk depends on type of grass pea preparation and on mixing with cereals and antioxidants. Trop. Med. Int. Health 2005, 10(2):169-178.
    • (2005) Trop. Med. Int. Health , vol.10 , Issue.2 , pp. 169-178
    • Getahun, H.1    Lambein, F.2    Vanhoorne, M.3    Van der Stuyft, P.4
  • 23
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration: where are we now?
    • Halliwell B. Oxidative stress and neurodegeneration: where are we now?. J. Neurochem. 2006, 97(6):1634-1658.
    • (2006) J. Neurochem. , vol.97 , Issue.6 , pp. 1634-1658
    • Halliwell, B.1
  • 24
    • 0035525733 scopus 로고    scopus 로고
    • Cellular stress response and apoptosis in cancer therapy
    • Herr I., Debatin K.M. Cellular stress response and apoptosis in cancer therapy. Blood 2001, 98(9):2603-2614.
    • (2001) Blood , vol.98 , Issue.9 , pp. 2603-2614
    • Herr, I.1    Debatin, K.M.2
  • 25
    • 33645843953 scopus 로고    scopus 로고
    • Glutamate, a neurotransmitter-and so much more A synopsis of Wierzba III
    • Hertz L. Glutamate, a neurotransmitter-and so much more A synopsis of Wierzba III. Neurochem. Int. 2006, 48(6-7):416-425.
    • (2006) Neurochem. Int. , vol.48 , Issue.6-7 , pp. 416-425
    • Hertz, L.1
  • 26
    • 0030049065 scopus 로고    scopus 로고
    • The presence of calbindin in rat cortical neurons protects in vitro from oxidative stress
    • Hugon J., Hugon F., Esclaire F., Lesort M., Diop A.G. The presence of calbindin in rat cortical neurons protects in vitro from oxidative stress. Brain Res. 1996, 707(2):288-292.
    • (1996) Brain Res. , vol.707 , Issue.2 , pp. 288-292
    • Hugon, J.1    Hugon, F.2    Esclaire, F.3    Lesort, M.4    Diop, A.G.5
  • 28
    • 0036813225 scopus 로고    scopus 로고
    • Thioltransferase (glutaredoxin) mediates recovery of motor neurons from excitotoxic mitochondrial injury
    • Kenchappa R.S., Diwakar L., Boyd M.R., Ravindranath V. Thioltransferase (glutaredoxin) mediates recovery of motor neurons from excitotoxic mitochondrial injury. J. Neurosci. 2002, 22(19):8402-8410.
    • (2002) J. Neurosci. , vol.22 , Issue.19 , pp. 8402-8410
    • Kenchappa, R.S.1    Diwakar, L.2    Boyd, M.R.3    Ravindranath, V.4
  • 29
    • 0028176074 scopus 로고
    • Excitotoxins l-β-oxalyl-amino-alanine (L-BOAA) and 3, 4, 6-trihydroxyphenylalanine (6-OH-DOPA) inhibit [3H] α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) binding in human hippocampus
    • Kunig G., Hartmann J., Niedermeyer B., Deckert J., Ransmayr G., Heinsen H., Beckmann H., Riederer P. Excitotoxins l-β-oxalyl-amino-alanine (L-BOAA) and 3, 4, 6-trihydroxyphenylalanine (6-OH-DOPA) inhibit [3H] α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) binding in human hippocampus. Neurosci. Lett. 1994, 169(1-2):219-222.
    • (1994) Neurosci. Lett. , vol.169 , Issue.1-2 , pp. 219-222
    • Kunig, G.1    Hartmann, J.2    Niedermeyer, B.3    Deckert, J.4    Ransmayr, G.5    Heinsen, H.6    Beckmann, H.7    Riederer, P.8
  • 30
    • 77949342146 scopus 로고    scopus 로고
    • Hind-limb paraparesis in a rat model for neurolathyrism associated with apoptosis and an impaired vascular endothelial growth factor system in the spinal cord
    • Kusama-Eguchi K., Yamazaki Y., Ueda T., Suda A., Hirayama Y., Ikegami F., Watanabe K., May M., Lambein F., Kusama T. Hind-limb paraparesis in a rat model for neurolathyrism associated with apoptosis and an impaired vascular endothelial growth factor system in the spinal cord. J. Compar. Neurol. 2010, 518(6):928-942.
    • (2010) J. Compar. Neurol. , vol.518 , Issue.6 , pp. 928-942
    • Kusama-Eguchi, K.1    Yamazaki, Y.2    Ueda, T.3    Suda, A.4    Hirayama, Y.5    Ikegami, F.6    Watanabe, K.7    May, M.8    Lambein, F.9    Kusama, T.10
  • 31
    • 34447527676 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: signaling the unfolded protein response
    • Lai E., Teodoro T., Volchuk A. Endoplasmic reticulum stress: signaling the unfolded protein response. Physiology (Bethesda) 2007, 22:193-201.
    • (2007) Physiology (Bethesda) , vol.22 , pp. 193-201
    • Lai, E.1    Teodoro, T.2    Volchuk, A.3
  • 32
    • 33645141853 scopus 로고    scopus 로고
    • ER stress and neurodegenerative diseases
    • Lindholm D., Wootz H., Korhonen L. ER stress and neurodegenerative diseases. Cell Death Differ. 2006, 13(3):385-392.
    • (2006) Cell Death Differ. , vol.13 , Issue.3 , pp. 385-392
    • Lindholm, D.1    Wootz, H.2    Korhonen, L.3
  • 33
    • 1342298186 scopus 로고    scopus 로고
    • Content of nitrogen compounds in raw and preserved seeds of grass pea (Lathyrus sativus L.)
    • Lisiewska Z., Kmiecik W., Korus A. Content of nitrogen compounds in raw and preserved seeds of grass pea (Lathyrus sativus L.). Eur. Food Res. Technol. 2001, 213(4-5):343-348.
    • (2001) Eur. Food Res. Technol. , vol.213 , Issue.4-5 , pp. 343-348
    • Lisiewska, Z.1    Kmiecik, W.2    Korus, A.3
  • 34
    • 0021740674 scopus 로고
    • Lathyrus excitotoxin - mechanism of neuronal excitation by l-2-oxalylamino-3-amino-propionic and l-3-oxalylamino-2-amino-propionic acid
    • Macdonald J.F., Morris M.E. Lathyrus excitotoxin - mechanism of neuronal excitation by l-2-oxalylamino-3-amino-propionic and l-3-oxalylamino-2-amino-propionic acid. Exper. Brain Res. 1984, 57(1):158-166.
    • (1984) Exper. Brain Res. , vol.57 , Issue.1 , pp. 158-166
    • Macdonald, J.F.1    Morris, M.E.2
  • 35
    • 0036640537 scopus 로고    scopus 로고
    • Cerebral cystine uptake: a tale of two transporters
    • McBean G.J. Cerebral cystine uptake: a tale of two transporters. Trends Pharmacol. Sci. 2002, 23(7):299-302.
    • (2002) Trends Pharmacol. Sci. , vol.23 , Issue.7 , pp. 299-302
    • McBean, G.J.1
  • 36
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
    • Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β. Nature 2000, 403(6765):98-103.
    • (2000) Nature , vol.403 , Issue.6765 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 38
    • 0027303783 scopus 로고
    • L-BOAA induces selective inhibition of brain mitochondrial enzyme, NADH-dehydrogenase
    • Pai K.S., Ravindranath V. L-BOAA induces selective inhibition of brain mitochondrial enzyme, NADH-dehydrogenase. Brain Res. 1993, 621(2):215-221.
    • (1993) Brain Res. , vol.621 , Issue.2 , pp. 215-221
    • Pai, K.S.1    Ravindranath, V.2
  • 39
    • 0033569575 scopus 로고    scopus 로고
    • Calcium dynamics and buffering in motoneurones of the mouse spinal cord. J. Physiol.
    • Palecek, J., Lips, M.B., Keller, B.U., 1999. Calcium dynamics and buffering in motoneurones of the mouse spinal cord. J. Physiol. 520 Pt 2: 485-502.
    • (1999) , vol.520 , Issue.PART 2 , pp. 485-502
    • Palecek, J.1    Lips, M.B.2    Keller, B.U.3
  • 40
    • 0019522935 scopus 로고
    • The neurolathyrogen, β-N-oxalyl-l-α,β-diaminopropionic acid, is a potent agonist at 'glutamate preferring' receptors in the frog spinal cord
    • Pearson S., Nunn P.B. The neurolathyrogen, β-N-oxalyl-l-α,β-diaminopropionic acid, is a potent agonist at 'glutamate preferring' receptors in the frog spinal cord. Brain Res. 1981, 206(1):178-182.
    • (1981) Brain Res. , vol.206 , Issue.1 , pp. 178-182
    • Pearson, S.1    Nunn, P.B.2
  • 41
    • 49049116292 scopus 로고    scopus 로고
    • Dystrophic neurites of senile plaques in Alzheimer's disease are deficient in cytochrome c oxidase
    • Perez-Gracia E., Torrejon-Escribano B., Ferrer I. Dystrophic neurites of senile plaques in Alzheimer's disease are deficient in cytochrome c oxidase. Acta Neuropathol. 2008, 116(3):261-268.
    • (2008) Acta Neuropathol. , vol.116 , Issue.3 , pp. 261-268
    • Perez-Gracia, E.1    Torrejon-Escribano, B.2    Ferrer, I.3
  • 42
    • 33947487342 scopus 로고
    • The isolation and characterization of β-N-Oxalyl-l-α,β-diaminopropionic acid: a neurotoxin from the seeds of Lathyrus Sativus
    • Rao S.L.N., Sarma P.S., Adiga P.R. The isolation and characterization of β-N-Oxalyl-l-α,β-diaminopropionic acid: a neurotoxin from the seeds of Lathyrus Sativus. Biochemistry 1964, 3(3):432-436.
    • (1964) Biochemistry , vol.3 , Issue.3 , pp. 432-436
    • Rao, S.L.N.1    Sarma, P.S.2    Adiga, P.R.3
  • 43
    • 0028947555 scopus 로고
    • Brainstem motoneuron pools that are selectively resistant in amyotrophic lateral sclerosis are preferentially enriched in parvalbumin: evidence from monkey brainstem for a calcium-mediated mechanism in sporadic ALS
    • Reiner A., Medina L., Figueredo-Cardenas G., Anfinson S. Brainstem motoneuron pools that are selectively resistant in amyotrophic lateral sclerosis are preferentially enriched in parvalbumin: evidence from monkey brainstem for a calcium-mediated mechanism in sporadic ALS. Exp.Neurol. 1995, 131(2):239-250.
    • (1995) Exp.Neurol. , vol.131 , Issue.2 , pp. 239-250
    • Reiner, A.1    Medina, L.2    Figueredo-Cardenas, G.3    Anfinson, S.4
  • 46
    • 0021957476 scopus 로고
    • β-N-Oxalylamino-l-alanine: action on high-affinity transport of neurotransmitters in rat brain and spinal cord synaptosomes
    • Ross S.M., Roy D.N., Spencer P.S. β-N-Oxalylamino-l-alanine: action on high-affinity transport of neurotransmitters in rat brain and spinal cord synaptosomes. J. Neurochem. 1985, 44(3):886-892.
    • (1985) J. Neurochem. , vol.44 , Issue.3 , pp. 886-892
    • Ross, S.M.1    Roy, D.N.2    Spencer, P.S.3
  • 47
    • 0024344673 scopus 로고
    • β-N-oxalylamino-l-alanine action on glutamate receptors
    • Ross S.M., Roy D.N., Spencer P.S. β-N-oxalylamino-l-alanine action on glutamate receptors. J. Neurochem. 1989, 53(3):710-715.
    • (1989) J. Neurochem. , vol.53 , Issue.3 , pp. 710-715
    • Ross, S.M.1    Roy, D.N.2    Spencer, P.S.3
  • 48
    • 0023183817 scopus 로고
    • Specific antagonism of behavioral action of uncommon amino-acids linked to motor-system diseases
    • Ross S.M., Spencer P.S. Specific antagonism of behavioral action of uncommon amino-acids linked to motor-system diseases. Synapse 1987, 1(3):248-253.
    • (1987) Synapse , vol.1 , Issue.3 , pp. 248-253
    • Ross, S.M.1    Spencer, P.S.2
  • 49
    • 0033519705 scopus 로고    scopus 로고
    • Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
    • Shimizu S., Narita M., Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 1999, 399(6735):483-487.
    • (1999) Nature , vol.399 , Issue.6735 , pp. 483-487
    • Shimizu, S.1    Narita, M.2    Tsujimoto, Y.3
  • 53
    • 0032535398 scopus 로고    scopus 로고
    • Thiol oxidation and loss of mitochondrial complex I precede excitatory amino acid-mediated neurodegeneration
    • Sriram K., Shankar S.K., Boyd M.R., Ravindranath V. Thiol oxidation and loss of mitochondrial complex I precede excitatory amino acid-mediated neurodegeneration. J. Neurosci. 1998, 18(24):10287-10296.
    • (1998) J. Neurosci. , vol.18 , Issue.24 , pp. 10287-10296
    • Sriram, K.1    Shankar, S.K.2    Boyd, M.R.3    Ravindranath, V.4
  • 54
    • 0030984173 scopus 로고    scopus 로고
    • The dietary excitotoxins β-N-methylamino-l-alanine and β-N-oxalylamino-l-alanine induce necrotic- and apoptotic-like death of rat cerebellar granule cells
    • Staton P.C., Bristow D.R. The dietary excitotoxins β-N-methylamino-l-alanine and β-N-oxalylamino-l-alanine induce necrotic- and apoptotic-like death of rat cerebellar granule cells. J. Neurochem. 1997, 69(4):1508-1518.
    • (1997) J. Neurochem. , vol.69 , Issue.4 , pp. 1508-1518
    • Staton, P.C.1    Bristow, D.R.2
  • 55
    • 0017589226 scopus 로고
    • The central nervous system in a case of neurolathyrism
    • Striefler M., Cohn D.F., Hirano A., Schujman E. The central nervous system in a case of neurolathyrism. Neurology 1977, 27(12):1176-1178.
    • (1977) Neurology , vol.27 , Issue.12 , pp. 1176-1178
    • Striefler, M.1    Cohn, D.F.2    Hirano, A.3    Schujman, E.4
  • 56
    • 0032817331 scopus 로고    scopus 로고
    • Bioactivation of cyanide to cyanate in sulfur amino acid deficiency: relevance to neurological disease in humans subsisting on cassava
    • Tor-Agbidye J., Palmer V.S., Lasarev M.R., Craig A.M., Blythe L.L., Sabri M.I., Spencer P.S. Bioactivation of cyanide to cyanate in sulfur amino acid deficiency: relevance to neurological disease in humans subsisting on cassava. Toxicol. Sci. 1999, 50(2):228-235.
    • (1999) Toxicol. Sci. , vol.50 , Issue.2 , pp. 228-235
    • Tor-Agbidye, J.1    Palmer, V.S.2    Lasarev, M.R.3    Craig, A.M.4    Blythe, L.L.5    Sabri, M.I.6    Spencer, P.S.7
  • 57
    • 0036713846 scopus 로고    scopus 로고
    • GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity
    • Van Damme P., Van Den Bosch L., Van Houtte E., Callewaert G., Robberecht W. GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity. J. Neurophysiol. 2002, 88(3):1279-1287.
    • (2002) J. Neurophysiol. , vol.88 , Issue.3 , pp. 1279-1287
    • Van Damme, P.1    Van Den Bosch, L.2    Van Houtte, E.3    Callewaert, G.4    Robberecht, W.5
  • 58
    • 0034319259 scopus 로고    scopus 로고
    • Different receptors mediate motor neuron death induced by short and long exposures to excitotoxicity
    • Van Den Bosch L., Robberecht W. Different receptors mediate motor neuron death induced by short and long exposures to excitotoxicity. Brain Res. Bull. 2000, 53(4):383-388.
    • (2000) Brain Res. Bull. , vol.53 , Issue.4 , pp. 383-388
    • Van Den Bosch, L.1    Robberecht, W.2
  • 61
    • 5144223916 scopus 로고    scopus 로고
    • The Lathyrus excitotoxin β-N-oxalyl-l-α,β-diaminopropionic acid is a substrate of the L-cystine/L-glutamate exchanger system xc-
    • Warren B.A., Patel S.A., Nunn P.B., Bridges R.J. The Lathyrus excitotoxin β-N-oxalyl-l-α,β-diaminopropionic acid is a substrate of the L-cystine/L-glutamate exchanger system xc-Toxicol. Appl. Pharmacol. 2004, 200(2):83-92.
    • (2004) Toxicol. Appl. Pharmacol. , vol.200 , Issue.2 , pp. 83-92
    • Warren, B.A.1    Patel, S.A.2    Nunn, P.B.3    Bridges, R.J.4
  • 62
    • 36949043950 scopus 로고
    • Central effects of β-N-oxalyl-α,β-diaminopropionic acid and other lathyrus factors
    • Watkins J.C., Curtis D.R., Biscoe T.J. Central effects of β-N-oxalyl-α,β-diaminopropionic acid and other lathyrus factors. Nature 1966, 211(5049):637.
    • (1966) Nature , vol.211 , Issue.5049 , pp. 637
    • Watkins, J.C.1    Curtis, D.R.2    Biscoe, T.J.3
  • 63
    • 0024466387 scopus 로고
    • Neurotoxicity of β-N-methylamino-l-alanine (BMAA) and β-N-oxalylamino-l-alanine (BOAA) on cultured cortical neurons
    • Weiss J.H., Koh J.Y., Choi D.W. Neurotoxicity of β-N-methylamino-l-alanine (BMAA) and β-N-oxalylamino-l-alanine (BOAA) on cultured cortical neurons. Brain Res. 1989, 497(1):64-71.
    • (1989) Brain Res. , vol.497 , Issue.1 , pp. 64-71
    • Weiss, J.H.1    Koh, J.Y.2    Choi, D.W.3
  • 64
    • 0028063544 scopus 로고
    • Neuroprotective effect of free radical scavengers on β-N-oxalylamino-l-alanine (BOAA)-induced neuronal damage in rat hippocampus
    • Willis C.L., Meldrum B.S., Nunn P.B., Anderton B.H., Leigh P.N. Neuroprotective effect of free radical scavengers on β-N-oxalylamino-l-alanine (BOAA)-induced neuronal damage in rat hippocampus. Neurosci. Lett. 1994, 182(2):159-162.
    • (1994) Neurosci. Lett. , vol.182 , Issue.2 , pp. 159-162
    • Willis, C.L.1    Meldrum, B.S.2    Nunn, P.B.3    Anderton, B.H.4    Leigh, P.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.