Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 3, 2011, Pages 330-340

  Wick, Marilee J ^a,c   Buesing, Erica J ^a   Wehling, Carol A ^c   Loomis, Zoe L ^a   Cool, Carlyne D ^b,d   Zamora, Martin R ^a   Miller, York E ^a,c   Colgan, Sean P ^b   Hersh, Louis B ^e   Voelkel, Norbert F ^a,f   Dempsey, Edward C ^a,c  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d DEPARTMENT OF MEDICINE   (United States)

^e UNIVERSITY OF KENTUCKY   (United States)

^f VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Oxidative stress; Protein degradation; Pulmonary hypertension; Smoking; Smooth muscle cell

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; MEMBRANE METALLOENDOPEPTIDASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE;

ADOLESCENT; ADULT; AEROBIC METABOLISM; ARTERY INTIMA PROLIFERATION; ARTERY MEDIA; ARTERY MUSCLE; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; FEMALE; HUMAN; HUMAN TISSUE; HYPOXIA; LUNG ALVEOLUS WALL; LUNG BLOOD VESSEL; MALE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ADOLESCENT; AGED; AIRWAY REMODELING; BLOTTING, WESTERN; CASE-CONTROL STUDIES; FEMALE; HUMANS; LUNG; MALE; MIDDLE AGED; NEPRILYSIN; PULMONARY ALVEOLI; PULMONARY ARTERY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; YOUNG ADULT;

EID: 79551562936     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201002-0154OC     Document Type: Article

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