Pulmonary neuroendocrine cell system in pediatric and adult lung disease

Microscopy Research and Technique

Volumn 37, Issue 1, 1997, Pages 107-113

  Gosney, John R ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

lung; neuroendocrine cells; peptides; tumourlets

Indexed keywords

BIOLOGICAL ORGANS; CELLS; CYTOLOGY; PHYSIOLOGICAL MODELS; PULMONARY DISEASES;

CELL SYSTEM; HUMAN LUNG; LUNG; NATURALLY OCCURRING; NEUROENDOCRINE CELLS; NORMAL STATE; PARACRINE; PULMONARY TISSUES; RESPIRATORY TRACT; TUMOURLET;

ANIMALS;

ARTICLE; CELL DENSITY; CELL PROLIFERATION; HISTOPATHOLOGY; HUMAN; INFLAMMATION; LUNG BIOPSY; LUNG DYSPLASIA; LUNG FIBROSIS; NEUROSECRETORY CELL; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SUDDEN INFANT DEATH SYNDROME;

EID: 0030944543     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0029(19970401)37:1<107::AID-JEMT11>3.0.CO;2-V     Document Type: Article

References (76)

1. Aguayo, S.M., King, T.E., Waldron, J.A., Sherritt, K.M., Kane, M.A., and Miller, Y.E. (1990) Increased pulmonary neuroendocrine cells with bombesin-like immunoreactivity in adult patients with eosinophilic granuloma. J. Clin. Invest., 86:838-844.
2. Aguayo, S.M., Miller, Y.E., Waldron, J.A., Bogin, R.M., Sunday, M.E., Staton, G.W., Beam, W.R., and King, T.E. (1992) Brief report: Idiopathic diffuse hyperplasia of pulmonary neuroendocrine cells and airways diseased. New Engl. J. Med., 327:1285-1288.
3. Allibone, R.O. and Gosney, J.R. (1990) Rapid changes in pulmonary endocrine cells in acute bronchopneumonic consolidation (abstract) J. Pathol., 161:347.
4. Ayvazian, L.F., Schneider, B., Gewirtz, G., and Yalow, R.S. (1975) Ectopic production of big ACTH in carcinoma of the lung: Its clinical usefulness as a biologic marker. Am. Rev. Respir. Dis., 111:279-287.
5. Becker, K.L., Monaghan, K.G., and Silva, O.L. (1980) Immunocytochemical localization of calcitonin in Kulchitsky cells of human lung Arch. Pathol. Lab. Med., 104:196-198.
6. Becker, K.L., Nash, D., Suva, O.L., Snider, R.H., and Moore, C.F. (1981) Increased serum and urinary calcitonin levels in patients with pulmonary disease. Chest, 79:211-216.
7. Becker, K.L., Silva, O.L., Snider, R.H., Moore, C.F., Geelhoed, G.W., and Nash, D. (1984) The pathophysiology of pulmonary calcitonin. In: The Endocrine Lung in Health and Disease. K.L. Becker and A.F. Gazdar, eds. Saunders, Philadelphia, pp. 277-299.
8. Bousbaa, H., Poron, F., and Fleury-Feith, J. (1994) Changes in chromogranin A-immunoreactive guinea-pig pulmonary neuroendocrine cells after sensitization and challenge with ovalbumin. Cell Tissue Res., 275:195-199.
9. Carabba, V.H., Sorokin, S.P., and Hoyt, R.F. (1985) Development of neuroepithelial bodies in intact and cultured lungs of fetal rats Am J. Anat., 173:1-27.
10. Cutz, E., Gillian, J.E., and Track, N.S. (1984) Pulmonary endocrine cells in the developing human lung and during neonatal adaptation. In: The Endocrine Lung in Health and Disease. K.L. Becker and A.F. Gazdar, eds. Saunders, Philadelphia, pp. 210-231.
11. Cutz, E., Gillan, J.E., and Bryan, A.C. (1985) Neuroendocrine cells in the developing human lung: Morphologic and functional consider-ations. Pediatr. Pulmonol., 1 (suppl.):S21-S29.
12. DiAugustine, R.P., Jahnke, G.D., and Talley, F. (1984) Endocrine cells of the guinea pig upper airways. Morphology, distribution, and disposition after xeno-transplantation in the nude mouse. In: The Endocrine Lung in Health and Disease. K.L. Becker and A.F. Gazdar, eds. Saunders, Philadelphia, pp. 232-248.
13. Dovey, M., Wisseman, C.L., Roggli, V.L., Roomans, G.M., Shelburne, J.D., and Spock, A. (1989) Ultrastructural morphology of the lung in cystic fibrosis. J. Submicrosc. Cytol. Pathol., 21:521-534.
14. Dupont, A.G., Somers, G., Van Steirteghem, A.C., Watson, F., and Vanhaelst, L. (1984) Ectopic adrenocorticotropin production: Disappearance after removal of inflammatory tissue. J. Clin. Endocrinol. Metab., 58:654-658.
15. Fukayama, M., Hayashi, Y., Shiozawa, Y., Furukawa, E., Funata, N., and Koike, M. (1990) Human chorionic gonadotropin alpha subunit in endocrine cells of fibrotic and neoplastic lung. Lab. Invest., 62:444-451.
16. Galan-Galan, F., Hurtado, J., Cano, R.P., and Peralta, M.G. (1982) High plasma calcitonin concentrations in chronic bronchitis. Br. Med. J., 285:850-851.
17. Gewirtz, G. and Yalow, R.S. (1974) Ectopic ACTH production in carcinoma of the lung. J. Clin. Invest., 53:1022-1032.
18. Ghatei, M.A., Sheppard, M.D., Henzen-Logman, S., Blank, M.A., Polak, J.M., and Bloom, S.R. (1983) Bombesin and vasoactive intestinal polypeptide in the developing lung: Marked changes in acute respiratory distress syndrome. J. Clin. Endocrinol. Metab., 57:1226-1232.
19. Gillan, J.E., Pape, K.E., and Cutz, E. (1986) Association of changes in bombesin immunoreactive neuroendocrine cells in lungs of newborn infants with persistent fetal circulation and brainstem damage due to birth asphyxia. Pediatr. Res., 20:828-833.
20. Gillan, J.E., Curran, C., O'Reilly, E., Cahalane, S.F., and Unwin, A.R. (1989) Abnormal patterns of pulmonary neuroendocrine cells in victims of sudden infant death syndrome. Paediatrics, 84:828-834.
21. Gosney, J.R. (1992) Pulmonary Endocrine Pathology: Endocrine Cells and Endocrine Tumours of the Lung. Butterworth-Heinemann. Oxford.
22. Gosney, J.R. (1993) Neuroendocrine cell populations in postnatal human lungs: Minimal variation from childhood to old age. Anat. Rec., 236:177-180.
23. Gosnev, J.R. (1994) The endocrine lung and its response to hypoxia. Thorax, 49:S25-S26.
24. Gosney, J.R., Sissons, M.C.J., and Allibone, R.O. (1988) Neuroendocrine cell populations in normal human lungs: A quantitative study. Thorax, 43:878-882.
25. Gosney, J.R., Sissons, M.C.J., Allibone, R.O., and Blakey, A.F. (1989a) Pulmonary endocrine cells in chronic bronchitis and emphysema. J. Pathol., 157:127-133.
26. Gosney, J., Heath, D., Smith, P., Harris, P., and Yacoub, M. (1989b) Pulmonary endocrine cells in pulmonary arterial disease. Arch. Pathol. Lab. Med., 113:337-341.
27. Gosney, J.R., Green, A.R.T., and Taylor, W. (1990) Appropriate and inappropriate neuroendocrine products in pulmonary tumourlets. Thorax, 45:679-683.
28. Gould, V.E., Linnoila, R.I., Memoli, V.A., and Warren, W.H. (1983) Neuroendocrine components of the bronchopulmonary tract: Hyperplasias, dysplasias and neoplasms. Lab. Invest., 49:519-537.
29. Hatano, S. and Strasser, T., eds. (1975) Primary Pulmonary Hypertension. W.H.O., Geneva.
30. Hernandez-Vasquez, A., Will, J.A., and Quay, W.B. (1978) A radioautographic study of the neuroepithelial bodies of the lungs in fetal and neoatal rabbits. Cell Tissue Res., 186:203-207.
31. 3H-thymidine labelling in viov. Anat. Rec., 227:340-350.
32. Hoyt, R.F., McNelly, N.A., McDowell, E.M., and Sorokin, S. (1991) Neuroepithelial bodies stimulate proliferation of airway epithelium in fetal hamster lung. Am. J. Physiol., 260:234-240.
33. Ito, T., Nakatani, Y., Nagahara, N., Ogawa, T., Shibegaki, T., and Kanisawa, M. (1987) Quantitative study of pulmonary endocrine cells in anencephaly. Lung, 165:297-304.
34. Johnson, D.E. and Georgieff, M.K. (1989) Pulmonary neuroendocrine cells. Their secretory products and their potential roles in health and chronic lung disease in infancy. Am. Rev. Respir. Dis., 140:1807-1813.
35. Johnson, D.E. and Wobken, J.D. (1987) Calcitonin gene-related peptide immunoreactivity in airway epithelial cells of the human fetus and infant. Cell Tissue Res., 250:579-583.
36. Johnson, D.E., Lock, J.E., Eide, R.P., and Thompson, T.R. (1982) Pulmonary neuroendoerine cells in hyaline membrane disease and bronchopulmonary dysplasia. Pediatr. Res., 16:446-454.
37. Johnson, D.E., Kulik, T.J., Lock, J.E., Eide, R.P., and Thompson, T.R. (1985) Bombesin-, calcitonin-, and serotonin-immunoreactive pulmonary neuroendoerine cells in acute and chronic neonatal lung disease. Pediatr. Pulmonol., 1 (suppl.):S13-S20.
38. Johnson, D.E., Wobken, J.D., and Landrum, B.G. (1988) Changes in bombesin, calcitonin and serotonin immunoreactive pulmonary neuroendocrine cells in cystic fibrosis and after prolonged mechanical ventilation. Am. Rev. Respir. Dis., 137:123-131.
39. Johnson, N.F., Wagner, J.C., and Wills, H.A. (1980) Endocrine cell proliferation in the rat lung following asbestos inhalation. Lung, 158:221-228.
40. King, K.A., Hua, J., Torday, J.S., Drazen, J.M., Graham, S.A., Shipp, M.A., and Sunday, M.E. (1993) CD10/Neutral endopeptidase 24.11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin-like peptides. J. Clin. Invest., 91:1969-1973.
41. Lauweryns, J.M. and Cokelaere, M. (1973a) Hypoxia-sensitive neuroepithelial bodies. Intrapulmonary secretory neuroreceptors, modulated by the CNS. Z. Zellforsch Mikroskop. Anat., 145:521-540.
42. Lauweryns, J.M. and Cokelaere, M. (1973b) Intrapulmonary neuroepithelial bodies: Hypoxia sensitive neuro-(chemo-)receptors, Experientia, 29:1384-1386.
43. Lauweryns, J.M. and Peuskens. J.C. (1972) Neuroepithelial bodies (neuroreceptor or secretory organs?) in human infant bronchial epithelium. Anat. Rec., 172:471-482.
44. Lauweryns, J.M., Cokelaere, M., Deleersnyder, M., and Liebens, M. (1977) Intrapulmonary neuro-epithelial bodies in newborn rabbits. Influence of hypoxia, hyperoxia, hypercapnia, nicotine, reserpine, L-Dopa and 5-HPT. Cell Tissue Res., 182:425-440.
45. Lauweryns, J.M., Cokelaere, M., Lerut, T., and Theunynck, P. (1978) Cross-circulation studies on the influence of hypoxia and hypoxaemia on the neuro-epithelial bodies in young rabbits. Cell Tissue Res., 193:373-386.
46. Lauweryns, J.M., De Bock, V., Verhofstad, A.A.J., and Steinbusch, H.W.M. (1982) Immunohistochemical localization of serotonin in intrapulmonary neuroepithelial bodies. Cell Tissue Res., 226:215-223.
47. Lauweryns, J.M., De Bock, V., Guelinckx, P., and Decramer, M. (1983) Effects of unilateral hypoxia on neuroepithelial bodies in rabbit lungs. J. Appl. Physiol., 55:1665-1668.
48. Linnoila, R.I. (1982) Effects of diethylnitrosamine on lung neuroendoerine cells. Exp. Lung Res., 3:225-236.
49. Madden, B.P., Gosney, J., Coghlan, J.G., Kamalvand, K., Caslin, A.W., Smith, P., Yacoub, M., and Heath, D. (1994) Pretransplant clinicopathological correlation in end stage primary pulmonary hypertension. Eur. Respir. J., 7:672-678.
50. Miller, Y.E. (1994) Pulmonary neuroendocrine cells and lung development: Dim outlines emerge. J. Clin. Invest., 91:1861.
51. Mulder, H., Silberbusch, J., Hackeng, W.H.L., Van der Meer, C., and den Ottolander, G.J.H. (1980) Hypercalcitoninaemia in patients with chronic inflammatory disease. Netherlands J. Med., 23:129-131.
52. Perrin, D.G., McDonald, T.J., and Cutz, E. (1991) Hyperplasia of bombesin-immunoreactive pulmonary neuroendocrine cells and neuroepithelial bodies in sudden infant death syndrome. Paediatr. Pathol., 11:431-447.
53. Polak, J., Becker, K.L., Becker, E., Cutz, E., Gail, D.B., Goniakowska-Witalinska, L., Gosney, J.R., Lauweryns, J.M., Linnoila, I., McDowell, E.M., Miller, Y.E., Scheuermann, D.W., Springall, D.R., Sunday, M.E., and Zaccone, G. (1993) Lung endocrine cell markers, peptides and amines. Anat. Rec., 236:169-171.
54. Roncalli, M., Springall, D.R., Maggioni, M., Moradoghli-Haftvani, A., Winter, R.J.D., Zhao, L., Coggi, G., and Polak, J.M. (1993) Early changes in the calcitonin gene-related peptide (CGRP) content of pulmonary endocrine cells concomitant with vascular remodelling in the hypoxic rat. Am. J. Respir. Cell Mol. Biol., 9:467-474.
55. Sarikas, S.N., Hoyt, R.F., and Sorokin, S.P. (1985) Ontogeny of small granule APUD cells in hamster lung: A morphological study. Anat. Rec., 213:396-409.
56. Schwartz, K.E., Wolfsen, A.R., Forster, B., and Odell, W.D. (1979) Calcitonin in non-thyroidal cancer. J. Clin. Endocrinol. Metab., 49:438-444.
57. Sheard, J.D.H. and Gosney, J.R. (1996) Endocrine cells in tumour-bearing lungs. Thorax., 51:721-726.
58. Sheppard, M.N., Johnson, N.F., Cole, G.A., Bloom, S.R., Marangos, P.J., and Polak, J.M. (1982) Neuron specific enolase immunostaining. A useful tool for the microscopical detection of endocrine cell hyperplasia in adult rats exposed to asbestos. Histochemistry, 74:505-513.
59. Smith, P., Heath, D., Yacoub, M., Madden, B., Caslin, A.W., and Gosney, J.R. (1990) The ultrastructure of plexogenic pulmonary arteriopathy. J. Pathol., 160:111-121.
60. Stahlman, M.T. and Gray, M.E. (1984) Ontogeny of neuroendocrine cells in human fetal lung. I. An electron microscopic study. Lab. Invest., 51:449-463.
61. Stahlman, M., Grey, M.E., and Kasselberg, A.G. (1985) Immunoreactive bombesin and calcitonin paracrine cells of human fetal and newborn airways. Pediatr. Pulmonol., 1 (suppl.):S6-S12.
62. Stanislawski, E.C., Hernandez-Garcia, J., Mora-Torres, M.A., and Abrajan-Polaneo, E. (1981) Lung neuroendocrine structures. Topography, morphology, composition and relation with intrinsic asthma (non-immune). Arch. Invest. Med., 12:559-577.
63. Sunday, M.E., Kaplan, L.M., Motoyama, E., Chin, W.W., and Spindel, E.R. (1988) Gastrin-releasing peptide (mammalian bombesin) gene expression in health and disease. Lab. Invest., 59:5-24.
64. Sunday, M.E., Hua, J., Dai, H.B., Nusrat, A., and Torday, J.S. (1990) Bombesin increases fetal lung growth and maturation in utero and in organ culture. Am. J. Respir. Cell Mol. Biol., 3:199-205.
65. Sunday, M.E., Hua, J., Torday, J.S., Reyes, B., and Shipp, M.A. (1992) CD10/Neutral endopeptidase 24.11 in developing human fetal lung. J. Clin. Invest., 90:2517-2525.
66. Sunday, M.E., Hua, J., Reyes, B., Masui, H., and Torday, J.S. (1993) Anti-bombesin monoclonal antibodies modulate fetal mouse lung growth and maturation in utero and in organ cultures. Anat. Rec., 236:25-32.
67. Sunday, M.E., Willett, C.G., Patidar, K., and Graham, S.A. (1994) Modulation of oncogene and tumour suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia. Lab. Invest., 70:875-888.
68. Tsutsumi, Y. (1989) Expression of the alpha subunit of human chorionic gonadotropin in normal and neoplastic neuroendocrine cells. An immunohistochemical study. Acta Pathol. Jpn., 39:413-419.
69. Tsutsumi, Y., Osamura, R.Y., Watanabe, K., and Yanaihara, N. (1983) Immunohistochemical studies on gastrin-releasing peptide and adrenocorticotropic hormone-containing cells in the human lung. Lab. Invest., 48:623-632.
70. Valdes-Dapena, M. (1980) Sudden infant death syndrome. A review of the medical literature 1974-1979. Paediatrics, 66:597-614.
71. Wharton, J., Polak, J.M., Bloom, S.R., Ghjatei, M.A., Solcia, E., and Brown, M.R. (1978) Bombesin-like immunoreactivity in the lung. Nature, 273:769-770.
72. Whitwell, F. (1955) Tumourlets of the lung. J. Pathol. Bacteriol., 70:529-541.
73. Wilson, N.J.E., Gosney, J.R., and Mayall, F. (1993) Endocrine cells in diffuse pulmonary fibrosis. Thorax, 48:1252-1256.
74. Wolf, P., Hall, C., and Kilbourn, J.P. (1986) Demonstration of calcitonin and calmodulin by immunoperoxidase in the cystic fibrosis lung. Chest, 89:327-330.
75. Wolfsen, A.R. and Odell, W.D. (1979) ProACTH: Use for early detection of lung cancer. Am. J. Med., 66:765-772.
76. Yiakoumakis, E., Proukakis, C., Raptis, Korres, A., Dondas, N., and Samaras, V. (1987) Calcitonin concentrations in lung cancer and non-malignant pulmonary diseases. Oncology, 44:145-149.