Mesohaem substitution reveals how haem electronic properties can influence the kinetic and catalytic parameters of neuronal NO synthase

Biochemical Journal

Volumn 433, Issue 1, 2011, Pages 163-174

  Tejero, Jesús ^a,f   Biswas, Ashis ^a,g   Haque, Mohammad Mahfuzul ^a   Wang, Zhi Qiang ^a,b   Hemann, Craig ^c   Varnado, Cornelius L ^d   Novince, Zachary ^a   Hille, Russ ^e   Goodwin, Douglas C ^d   Stuehr, Dennis J ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b KENT STATE UNIVERSITY   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d AUBURN UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^g INDIAN INSTITUTE OF TECHNOLOGY BHUBANESWAR   (India)

Author keywords

Electron transfer; Flavoprotein; Haemprotein; Mesohaem; Nitric oxide; Nitric oxide synthase (NOS)

Indexed keywords

CARRIER PROTEIN; FERRIC ION; HAEM TRANSPORTER PROTEIN; HEME; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CATALYSIS; COMPUTER SIMULATION; CONTROLLED STUDY; DISSOCIATION; ELECTRON TRANSPORT; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; REDUCTION KINETICS; STEADY STATE; SURFACE PROPERTY; SYNTHESIS; WILD TYPE;

BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; CATALYSIS; ELECTRONS; HEME; KINETICS; MESOPORPHYRINS; NITRIC OXIDE SYNTHASE TYPE I; OXIDATION-REDUCTION;

BACTERIA (MICROORGANISMS);

EID: 79551500636     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101353     Document Type: Article

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