A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases

Journal of Antibiotics

Volumn 64, Issue 1, 2011, Pages 9-17

  Saruwatari, Takayoshi ^a   Praseuth, Alex P ^b   Sato, Michio ^a   Torikai, Kohei ^a   Noguchi, Hiroshi ^a   Watanabe, Kenji ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b BioPharmaceuticals Formulation Development   (United States)

Author keywords

biosynthesis; fungi; heterologous expression; iterative; PKS

Indexed keywords

BIKAVERIN; GENOMIC DNA; HYPOTHEMYCIN; MACROLIDE; POLYKETIDE; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG; ZEARALENONE;

DIELS ALDER REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE CLUSTER; GIBBERELLA FUJIKUROI; NONHUMAN; PRIORITY JOURNAL; REVIEW;

GENOME, FUNGAL; POLYKETIDE SYNTHASES; XANTHONES; ZEARALENONE;

ESCHERICHIA COLI; FUNGI;

EID: 79251612884     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2010.130     Document Type: Review

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