Hydrolytic polyketide shortening by Ayg1p, a novel enzyme involved in fungal melanin biosynthesis

Journal of Biological Chemistry

Volumn 279, Issue 43, 2004, Pages 44613-44620

  Fujii, Isao ^a   Yasuoka, Yoshinori ^a   Tsai, Huei Fung ^b   Chang, Yun C ^b   Kwon Chung, K J ^b   Ebizukal, Yutaka ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; ENZYME INHIBITION; ESCHERICHIA COLI; PROTEINS; VIRUSES;

1,3,6,8-TETRALIDROXYNAPTHALENE (T4HN); HYDROLYTIC POLYKETIDE; VIRULENCE FACTOR;

ENZYMES;

ACETOACETIC ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; MELANIN; NAPHTHALENE DERIVATIVE; POLYKETIDE; SERINE PROTEINASE;

AMINO ACID SEQUENCE; ARTICLE; ASPERGILLUS ORYZAE; BIOSYNTHESIS; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; HYDROLYSIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; STATISTICAL SIGNIFICANCE;

ACETOACETATES; AMINO ACID MOTIFS; ASPARTIC ACID; ASPERGILLUS FUMIGATUS; ASPERGILLUS ORYZAE; BINDING SITES; CARBON; CARBON-CARBON LYASES; CATALYSIS; CATALYTIC DOMAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; HISTIDINE; HYDROLYSIS; KINETICS; MASS SPECTROMETRY; MELANINS; MODELS, CHEMICAL; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; MUTATION; NAPHTHOLS; PLASMIDS; PYRONES; SERINE; SUBSTRATE SPECIFICITY;

ASPERGILLUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS ORYZAE; ESCHERICHIA COLI; FUNGI;

EID: 7244253075     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406758200     Document Type: Article

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