Expression of toll-like receptor 9 in lungs of pigs, dogs and cattle

International Journal of Experimental Pathology

Volumn 92, Issue 1, 2011, Pages 1-7

  Schneberger, David ^a   Lewis, Danyse ^a   Caldwell, Sarah ^a   Singh, Baljit ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Immuno electron microscopy; Pulmonary intravascular macrophages; TLR9

Indexed keywords

TOLL LIKE RECEPTOR 9;

ANIMAL TISSUE; ARTICLE; CATTLE; CONTROLLED STUDY; DOG; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; LUNG; LUNG ALVEOLUS MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; SWINE; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CATTLE; DOGS; IMMUNOHISTOCHEMISTRY; LUNG; MICE; MICROSCOPY, IMMUNOELECTRON; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; SWINE; TOLL-LIKE RECEPTOR 9;

EID: 79251540244     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2010.00742.x     Document Type: Article

References (47)

1. Aharonson-Raz K. & Singh B. (2010) Pulmonary intravascular macrophages and endotoxin-induced pulmonary pathophysiology in horses. Can. J. Vet. Res. 74, 45-49.
2. Andonegui G., Bonder C.S., Green F. et al. (2003) Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J. Clin. Invest. 111, 1011-1020.
3. Bafica A., Scanga C.A., Feng C.G., Leifer C., Cheever A., Sher A. (2005) TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J. Exp. Med. 202, 1715-1724.
4. Banchereau J., Briere F., Caux C. et al. (2000) Immunobiology of dendritic cells. Annu. Rev. Immunol. 18, 767-811.
5. Bhan U., Trujillo G., Lyn-Kew K. et al. (2008) Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila. Infect. Immun. 76, 2895-2904.
6. Burgener I.A. & Jungi T.W. (2008) Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet. Immunol. Immunopathol. 124, 184-191.
7. Chen L., Arora M., Yarlagadda M. et al. (2006) Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide. J. Immunol. 177, 2373-2383.
8. Chiers K., Donne E., Van Overbeke I., Ducatelle R., Haesebrouck F. (2002) Actinobacillus pleuropneumoniae infections in closed swine herds: infection patterns and serological profiles. Vet. Microbiol. 85, 343-352.
9. Demedts I.K., Bracke K.R., Maes T., Joos G.F., Brusselle G.G. (2006) Different roles for human lung dendritic cell subsets in pulmonary immune defense mechanisms. Am. J. Respir. Cell Mol. Biol. 35, 387-393.
10. Dorn A. & Kippenberger S. (2008) Clinical application of CpG-, non-CpG-, and antisense oligodeoxynucleotides as immunomodulators. Curr. Opin. Mol. Ther. 10, 10-20.
11. Eaton-Bassiri A., Dillon S.B., Cunningham M. et al. (2004) Toll-like receptor 9 can be expressed at the cell surface of distinct populations of tonsils and human peripheral blood mononuclear cells. Infect. Immun. 72, 7202-7211.
12. Ewaschuk J.B., Backer J.L., Churchill T.A., Obermeier F., Krause D.O., Madsen K.L. (2007) Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA. Infect. Immun. 75, 2572-2579.
13. Frieri M. (2005) Asthma concepts in the new millennium: update in asthma pathophysiology. Allergy Asthma Proc. 26, 83-88.
14. Goodnow R.A. (1980) Biology of Bordetella bronchiseptica. Microbiol. Rev. 44, 722-738.
15. Hashimoto M., Asahina Y., Sano J., Kano R., Moritomo T., Hasegawa A. (2005) Cloning of canine toll-like receptor 9 and its expression in dog tissues. Vet. Immunol. Immunopathol. 106, 159-163.
16. Hemmi H., Takeuchi O., Kawai T. et al. (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745.
17. Hong Z., Jiang Z., Liangxi W. et al. (2004) Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release. Int. Immunopharmacol. 4, 223-234.
18. Hu Z., Sun S., Zhou F. (2003) The binding of CpG-oligodeoxynucleotides to cell-surface and its immunostimulatory activity are modulated by extracellular acidic pH. Vaccine 21, 485-490.
19. Jozsef L., Khreiss T., Filep J.G. (2004) CpG motifs in bacterial DNA delay apoptosis of neutrophil granulocytes. FASEB J. 18, 1776-1778.
20. Kline J.N., Waldschmidt T.J., Businga T.R. et al. (1998) Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J. Immunol. 160, 2555-2559.
21. Krieg A.M. (2002) CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20, 709-760.
22. Krieg A.M., Yi A.K., Matson S. et al. (1995) CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374, 546-549.
23. Kuramoto E., Yano O., Kimura Y. et al. (1992) Oligonucleotide sequences required for natural killer cell activation. Jpn. J. Cancer Res. 83, 1128-1131.
24. Larkin M.A., Blackshields G., Brown N.P. et al. (2007) ClustalW and ClustalX version 2. Bioinformatics 23, 2947-2948.
25. Latz E., Schoenemeyer A., Visintin A. et al. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat. Immunol. 5, 190-198.
26. Li J., Ma Z., Tang Z.L., Stevens T., Pitt B., Li S. (2004) CpG DNA-mediated immune response in pulmonary endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 287, L552-L558.
27. Macfarlane D.E. & Manzel L. (1998) Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds. J. Immunol. 160, 1122-1131.
28. Morsey M.A., Van-Kessel A.G., Mori Y. et al. (1999) Cytokine profiles following interaction between bovine alveolar macrophages and Pasteurella haemolytica. Microb. Pathog. 26, 325-331.
29. Parbhakar O.P., Duke T., Townsend H.G., Singh B. (2004) Immunophenotypic characterization and depletion of pulmonary intravascular macrophages of horses. Vet. Res. 35, 39-51.
30. Platz J., Beisswenger C., Dalpke A. et al. (2004) Microbial DNA induces a host defense reaction of human respiratory epithelial cells. J. Immunol. 173, 1219-1223.
31. Ramirez-Ortiz Z.G., Specht C.A., Wang J.P. et al. (2008) Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA. Infect. Immun. 76, 2123-2129.
32. Rankin R., Pontarollo R., Ioannou X. et al. (2001) CpG motif identification for veterinary and laboratory species demonstrates that sequence recognition is highly conserved. Antisense Nucleic Acid Drug Dev. 11, 333-340.
33. Rankin R., Pontarollo R., Gomis S. et al. (2002) CpG-containing oligodeoxynucleotides augment and switch the immune responses of cattle to bovine herpesvirus-1 glycoprotein D. Vaccine 20, 3014-3022.
34. Roach J.C., Glusman G., Rowen L. et al. (2005) The evolution of vertebrate Toll-like receptors. Proc. Natl Acad. Sci. USA 102, 9577-9582.
35. Rutz M., Metzger J., Gellert T. et al. (2004) Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Eur. J. Immunol. 34, 2541-2550.
36. Schneberger D., Caldwell S., Suri S.S., Singh B. (2009) Expression of toll-like receptor 9 in horse lungs. Anat. Rec. 292, 1068-1077.
37. Schwartz D.A., Quinn T.J., Thorne P.S., Sayeed S., Yi A.K., Krieg A.M. (1997) CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract. J. Clin. Invest. 100, 68-73.
38. Schwartz D.A., Wohlford-Lenane C.L., Quinn T.J., Krieg A.M. (1999) Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway. J. Immunol. 163, 224-231.
39. Senthilselvan A., Dosman J.A., Chenard L. et al. (2009) Toll-like receptor 4 variants reduce airway response in human subjects at high endotoxin levels in a swine facility. J. Allergy Clin. Immunol. 123, 1034-1040, 1040.e1-1040.e2.
40. Shimosato T., Tohno M., Kitazawa H. et al. (2005) Toll-like receptor 9 is expressed on follicle-associated epithelia containing M cells in swine Peyer's patches. Immunol. Lett. 98, 83-89.
41. Singh Suri S., Janardhan K.S., Parbhakar O., Caldwell S., Appleyard G., Singh B. (2006) Expression of toll-like receptor 4 and 2 in horse lungs. Vet. Res. 37, 541-551.
42. Singh B., Pearce J.W., Gamage L.N., Janardhan K., Caldwell S. (2004) Depletion of pulmonary intravascular macrophages inhibits acute lung inflammation. Am. J. Physiol. Lung Cell. Mol. Physiol. 286, L363-L372.
43. Tohno M., Shimosato T., Moue M. et al. (2006) Toll-like receptor 2 and 9 are expressed and functional in gut-associated lymphoid tissues of presuckling newborn swine. Vet. Res. 37, 791-812.
44. Wassef A., Janardhan K., Pearce J.W., Singh B. (2004) Toll-like receptor 4 in normal and inflamed lungs and other organs of pig, dog and cattle. Histol. Histopathol. 19, 1201-1208.
45. Yeo S.J., Yoon J.G., Hong S.C., Yi A.K. (2003) CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression. J. Immunol. 170, 1052-1061.
46. Zhang Y.W., Davis E.G., Blecha F., Wilkerson M.J. (2008) Molecular cloning and characterization of equine Toll-like receptor 9. Vet. Immunol. Immunopathol. 124, 209-219.
47. Zimmermann S., Dalpke A., Heeg K. (2008) CpG oligonucleotides as adjuvant in therapeutic vaccines against parasitic infections. Int. J. Med. Microbiol. 298, 39-44.