Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway

Journal of Immunology

Volumn 163, Issue 1, 1999, Pages 224-231

  Schwartz, David A ^a,b   Wohlford Lenane, Christine L ^b   Quinn, Timothy J ^b   Krieg, Arthur M ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; MACROPHAGE INFLAMMATORY PROTEIN 2; OLIGONUCLEOTIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CPG ISLAND; CYTOKINE RELEASE; DNA METHYLATION; DOSE RESPONSE; GENE DISRUPTION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE COUNT; LOWER RESPIRATORY TRACT INFECTION; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ADMINISTRATION, INHALATION; ANIMALS; CPG ISLANDS; DNA METHYLATION; DNA, BACTERIAL; INFLAMMATION; INJECTIONS, INTRAVENOUS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGONUCLEOTIDES;

EID: 0033168959     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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