Modeling single nucleotide polymorphisms in the human akr1c1 and akr1c2 genes: Implications for functional and genotyping analyses

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Arthur, Jonathan W ^a   Reichardt, Juergen K V ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b JAMES COOK UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN AKR1C1; PROTEIN AKR1C2; UNCLASSIFIED DRUG; 3 ALPHA BETA, 20 BETA HYDROXYSTEROID DEHYDROGENASE; 3 ALPHA-BETA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE; 3ALPHA(OR 20BETA) HYDROXYSTEROID DEHYDROGENASE; AKR1C2 PROTEIN, HUMAN; ANDROSTANOLONE; HYDROXYSTEROID DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

AKR1C1 GENE; AKR1C2 GENE; ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; GENE; GENE STRUCTURE; GENETIC ANALYSIS; GENOTYPE; HUMAN; HYDROGEN BOND; PREDICTION; SINGLE NUCLEOTIDE POLYMORPHISM; BINDING SITE; BIOLOGICAL MODEL; CHEMISTRY; CONFORMATION; GENETICS; KINETICS; METABOLISM; MUTATION; PROTEIN SECONDARY STRUCTURE; SURFACE PROPERTY;

20-HYDROXYSTEROID DEHYDROGENASES; BINDING SITES; DIHYDROTESTOSTERONE; GENOTYPE; HUMANS; HYDROGEN BONDING; HYDROXYSTEROID DEHYDROGENASES; KINETICS; MODELS, GENETIC; MOLECULAR CONFORMATION; MUTATION; NADP; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN STRUCTURE, SECONDARY; SURFACE PROPERTIES;

EID: 79251526528     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015604     Document Type: Article

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