Structure of the Human 3α-Hydroxysteroid Dehydrogenase Type 3 in Complex with Testosterone and NADP at 1.25-Å Resolution

Journal of Biological Chemistry

Volumn 276, Issue 45, 2001, Pages 42091-42098

  Nahoum, Virginie ^c   Gangloff, Anne ^c   Legrand, Pierre ^c   Zhu, Dao Wei ^c   Cantin, Line ^c   Zhorov, Boris S ^a   Luu The, Van ^c   Labrie, Fernand ^c   Breton, Rock ^b   Lin, Sheng Xiang ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYMES; HORMONES; HYDROGEN BONDS;

SEQUENCE HOMOLOGY;

BIOCHEMISTRY;

3ALPHA HYDROXYSTEROID DEHYDROGENASE; 3ALPHA HYDROXYSTEROID DEHYDROGENASE 3; ANDROSTANEDIOL; ANDROSTANOLONE; ANDROSTENEDIONE; HISTIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERINE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG; 3 ALPHA HYDROXYSTEROID DEHYDROGENASE (B SPECIFIC); 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; HYDROXYSTEROID DEHYDROGENASE; ISOENZYME;

AMINO ACID SUBSTITUTION; ARTICLE; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; HORMONE BINDING; HUMAN; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY; STEROID METABOLISM; BINDING SITE; CHEMISTRY; METABOLISM;

17-HYDROXYSTEROID DEHYDROGENASES; 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (B-SPECIFIC); 3-HYDROXYSTEROID DEHYDROGENASES; BINDING SITES; HUMANS; ISOENZYMES; NADP; TESTOSTERONE;

EID: 0035834637     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105610200     Document Type: Article

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