Human atrial β 1L-adrenoceptor but not β 3- adrenoceptor activation increases force and Ca 2+ current at physiological temperature

British Journal of Pharmacology

Volumn 162, Issue 4, 2011, Pages 823-839

  Christ, Torsten ^a   Molenaar, Peter ^b   Klenowski, Paul M ^b   Ravens, Ursula ^c,d   Kaumann, Alberto J ^e  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d THE PRINCE CHARLES HOSPITAL   (Australia)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

1L adrenoceptors; 3 adrenoceptors; ( ) bupranolol; ( ) CGP12177; BRL37344; human atrial force and I Ca L; L 748,337; SR58611

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; AMIBEGRON; BETA 1 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; CALCIUM ION;

AGED; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DRUG EFFECT; DRUG RESPONSE; FEMALE; HEART ATRIUM CONTRACTILITY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART RIGHT ATRIUM; HUMAN; HUMAN CELL; HUMAN TISSUE; INOTROPISM; LOW TEMPERATURE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; AGED; ATRIAL APPENDAGE; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; ETHANOLAMINES; FEMALE; HUMANS; KINETICS; MALE; MIDDLE AGED; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PROPANOLAMINES; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, ADRENERGIC, BETA-3; TEMPERATURE; TETRAHYDRONAPHTHALENES;

EID: 79251480084     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00996.x     Document Type: Article

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