Binding of (-)-[3H]-CGP12177 at two sites in recombinant human β1-adrenoceptors and interaction with β-blockers

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 369, Issue 5, 2004, Pages 525-532

  Joseph, Shirin S ^a   Lynham, James A ^a   Colledge, William H ^a   Kaumann, Alberto J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Adrenoceptor blocking agents; Human 1 adrenoceptors; Two binding sites for ( ) 3H CGP12177

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ADENOSINE PHOSPHATE; ALPRENOLOL; ATENOLOL; BETA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; BUPRANOLOL; CARVEDILOL; ISOPRENALINE; METOPROLOL; NADOLOL; OXPRENOLOL; PINDOLOL; PROPRANOLOL; SOTALOL; TIMOLOL; CYCLIC AMP; PROPANOLAMINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHO CELL; COMPARATIVE STUDY; CORRELATION ANALYSIS; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; RECEPTOR AFFINITY; ANIMAL; CRICETULUS; DRUG INTERACTION; HAMSTER; METABOLISM;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP; DRUG INTERACTIONS; HUMANS; PROPANOLAMINES; RECEPTORS, ADRENERGIC, BETA-1;

EID: 2442702676     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-004-0884-y     Document Type: Article

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