-
1
-
-
0020523811
-
CGP12177: a hydrophilic β-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells
-
Staehelin M., Simons P., Jaeggi K., Wigger N. CGP12177: a hydrophilic β-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells. J. Biol. Chem. 1983; 258: 3496 – 3502
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 3496-3502
-
-
Staehelin, M.1
Simons, P.2
Jaeggi, K.3
Wigger, N.4
-
2
-
-
0020339975
-
Rapid and reversible disappearence of β-adrenergic cell surface receptors
-
Staehelin M., Simons P. Rapid and reversible disappearence of β-adrenergic cell surface receptors. EMBO J. 1982; 1: 187 – 190
-
(1982)
EMBO J.
, vol.1
, pp. 187-190
-
-
Staehelin, M.1
Simons, P.2
-
3
-
-
0021088173
-
Determination of the desensitization of β-adrenergic receptors by [3H]CCP-12177
-
Hertel C., Müller P., Portenier M., Staehelin M. Determination of the desensitization of β-adrenergic receptors by [3H]CCP-12177. Biochem. J. 1983; 216: 669 – 674
-
(1983)
Biochem. J.
, vol.216
, pp. 669-674
-
-
Hertel, C.1
Müller, P.2
Portenier, M.3
Staehelin, M.4
-
4
-
-
0022975277
-
Desensitization of the β-adrenergic receptor-coupled adenylate cyclase in cultured mammalian cells: receptor sequestration versus receptor function
-
Kassis S., Olasmaa M., Sullivan M., Fishman P. H. Desensitization of the β-adrenergic receptor-coupled adenylate cyclase in cultured mammalian cells: receptor sequestration versus receptor function. J. Biol. Chem. 1986; 261: 12233 – 12237
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 12233-12237
-
-
Kassis, S.1
Olasmaa, M.2
Sullivan, M.3
Fishman, P.H.4
-
5
-
-
0019730196
-
Presence of bothbeta 1beta2adrenergic receptors in a single cell type
-
Homburger V., Lucas M., Rosenbaum E., Vassent G., Bockaert J. Presence of bothbeta 1beta2adrenergic receptors in a single cell type. Mol. Pharmacol. 1981; 20: 463 – 469
-
(1981)
Mol. Pharmacol.
, vol.20
, pp. 463-469
-
-
Homburger, V.1
Lucas, M.2
Rosenbaum, E.3
Vassent, G.4
Bockaert, J.5
-
6
-
-
0024405758
-
The β-adrenergic radioligand [3H] CGP-12177, generally classified as an antagonist, is a thermogenic agonist in brown adipose tissue
-
Mohell N., Dicker A. The β-adrenergic radioligand [3H] CGP-12177, generally classified as an antagonist, is a thermogenic agonist in brown adipose tissue. Biochem. J. 1989; 261: 401 – 405
-
(1989)
Biochem. J.
, vol.261
, pp. 401-405
-
-
Mohell, N.1
Dicker, A.2
-
7
-
-
0025969595
-
Adenylate cyclase agonist properties of CGP-12177A in brown fat: evidence for atypical β-adrenergic receptors
-
Scarpace P. J., Matheny M. Adenylate cyclase agonist properties of CGP-12177A in brown fat: evidence for atypical β-adrenergic receptors. Am. J. Physiol. 1991; 260: E226 – E231
-
(1991)
Am. J. Physiol.
, vol.260
, pp. E226-E231
-
-
Scarpace, P.J.1
Matheny, M.2
-
8
-
-
0026090708
-
CGP 12177A modulates brown fat adenylate cyclase activity by interacting with two distinct receptor sites
-
Granneman J. G., Whitty C. J. CGP 12177A modulates brown fat adenylate cyclase activity by interacting with two distinct receptor sites. J. Pharmacol. Exp. Ther. 1991; 256: 421 – 425
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.256
, pp. 421-425
-
-
Granneman, J.G.1
Whitty, C.J.2
-
9
-
-
0025827764
-
Coexistence of three β-adrenoceptor subtypes in white fat cells of various mammalian species
-
Langin D., Portillo M. P., Saulnier-Blache J.-S., Lafontan M. Coexistence of three β-adrenoceptor subtypes in white fat cells of various mammalian species. Eur. J. Pharmacol. 1991; 199: 291 – 301
-
(1991)
Eur. J. Pharmacol.
, vol.199
, pp. 291-301
-
-
Langin, D.1
Portillo, M.P.2
Saulnier-Blache, J.-S.3
Lafontan, M.4
-
10
-
-
0025876222
-
Atypical β-adrenergic receptor in 3T3-F442A adipocytes. Pharmacological and molecular relationship with the human β3-adrenergic receptor
-
Feve B., Emorine L. J., Lasnier F., Blin N., Baude B., Nahmias C., Strosberg A. D., Pairault J. Atypical β-adrenergic receptor in 3T3-F442A adipocytes. Pharmacological and molecular relationship with the human β3-adrenergic receptor. J. Biol. Chem. 1991; 266: 20329 – 20336
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 20329-20336
-
-
Feve, B.1
Emorine, L.J.2
Lasnier, F.3
Blin, N.4
Baude, B.5
Nahmias, C.6
Strosberg, A.D.7
Pairault, J.8
-
11
-
-
0027144733
-
Evidence for a functional β3-adrenoceptor in man
-
Lönnqvist F., Krief S., Strosberg A. D., Nyberg B., Emorine L. J., Arner P. Evidence for a functional β3-adrenoceptor in man. Br. J. Pharmacol. 1993; 110: 929 – 936
-
(1993)
Br. J. Pharmacol.
, vol.110
, pp. 929-936
-
-
Lönnqvist, F.1
Krief, S.2
Strosberg, A.D.3
Nyberg, B.4
Emorine, L.J.5
Arner, P.6
-
12
-
-
0024470363
-
Molecular characterization of the human β3-adrenergic receptor
-
Emorine L. J., Marullo S., Briend-Sutren M.-M., Patey G., Tate K., Delavier-Klutchko C., Strosberg A. D. Molecular characterization of the human β3-adrenergic receptor. Science (Washington D. C.) 1989; 245: 1118 – 1121
-
(1989)
Science (Washington D. C.)
, vol.245
, pp. 1118-1121
-
-
Emorine, L.J.1
Marullo, S.2
Briend-Sutren, M.-M.3
Patey, G.4
Tate, K.5
Delavier-Klutchko, C.6
Strosberg, A.D.7
-
13
-
-
0026325126
-
Molecular cloning and expression of the rat β3-adrenergic receptor
-
Granneman J. G., Lahners K. N., Chaudhry A. Molecular cloning and expression of the rat β3-adrenergic receptor. Mol. Pharmacol. 1991; 40: 895 – 899
-
(1991)
Mol. Pharmacol.
, vol.40
, pp. 895-899
-
-
Granneman, J.G.1
Lahners, K.N.2
Chaudhry, A.3
-
14
-
-
0026343747
-
An adipose tissue-specific β-adrenergic receptor. Molecular cloning and down-regulation in obesity
-
Muzzin P., Revelli J.-P., Kuhne F., Gocayne J. F., McCombie W. R., Venter J. C., Giacobino J.-P., Fraser C. M. An adipose tissue-specific β-adrenergic receptor. Molecular cloning and down-regulation in obesity. J. Biol. Chem. 1991; 266: 24053 – 24058
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 24053-24058
-
-
Muzzin, P.1
Revelli, J.-P.2
Kuhne, F.3
Gocayne, J.F.4
McCombie, W.R.5
Venter, J.C.6
Giacobino, J.-P.7
Fraser, C.M.8
-
15
-
-
0026530611
-
Radioligand binding studies of the atypical β3-adrenergic receptor in rat brown adipose tissue using [3H]CGP 12177
-
Muzzin P., Revelli J.-P., Fraser C. M., Giacobino J.-P. Radioligand binding studies of the atypical β3-adrenergic receptor in rat brown adipose tissue using [3H]CGP 12177. FEBS Lett. 1992; 298: 162 – 164
-
(1992)
FEBS Lett.
, vol.298
, pp. 162-164
-
-
Muzzin, P.1
Revelli, J.-P.2
Fraser, C.M.3
Giacobino, J.-P.4
-
16
-
-
0027483225
-
Expression of the β3-adrenergic receptor in human white adipose tissue
-
Revelli J.-P., Muzzin P., Paoloni A., Moinat M., Giacobino J.-P. Expression of the β3-adrenergic receptor in human white adipose tissue. J. Mol. Endocrinol. 1993; 10: 193 – 197
-
(1993)
J. Mol. Endocrinol.
, vol.10
, pp. 193-197
-
-
Revelli, J.-P.1
Muzzin, P.2
Paoloni, A.3
Moinat, M.4
Giacobino, J.-P.5
-
17
-
-
0027761394
-
Structural, and conformational features determining selective signal transduction in the β3-adrenergic receptor
-
Blin N., Camoin L., Maigret B., Strosberg A. D. Structural, and conformational features determining selective signal transduction in the β3-adrenergic receptor. Mol. Pharmacol. 1993; 44: 1094 – 1104
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 1094-1104
-
-
Blin, N.1
Camoin, L.2
Maigret, B.3
Strosberg, A.D.4
-
19
-
-
0026026206
-
Expression of three human β-adrenergic-receptor subtypes in transfected Chinese hamster ovary cells
-
Tate K. M., Briend-Sutren M.-M., Emorine L. J., Delavier-Klutchko C., Marullo S., Strosberg A. D. Expression of three human β-adrenergic-receptor subtypes in transfected Chinese hamster ovary cells. Eur. J. Biochem. 1991; 196: 357 – 361
-
(1991)
Eur. J. Biochem.
, vol.196
, pp. 357-361
-
-
Tate, K.M.1
Briend-Sutren, M.-M.2
Emorine, L.J.3
Delavier-Klutchko, C.4
Marullo, S.5
Strosberg, A.D.6
-
20
-
-
0003083826
-
cDNA for the human β2-adrenergic receptor: a protein with multiple membrane-spaning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platlet-derived growth factor
-
Kobilka B. K., Dixon R. A. F., Frielle T., Dohlman H. G., Bolanowski M. A., Sigal I. S., Yang-Feng T. L., Francke U., Caron M. G., Lefkowitz R. J. cDNA for the human β2-adrenergic receptor: a protein with multiple membrane-spaning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platlet-derived growth factor. Proc. Natl. Acad. Sci. USA 1987; 84: 46 – 50
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 46-50
-
-
Kobilka, B.K.1
Dixon, R.A.F.2
Frielle, T.3
Dohlman, H.G.4
Bolanowski, M.A.5
Sigal, I.S.6
Yang-Feng, T.L.7
Francke, U.8
Caron, M.G.9
Lefkowitz, R.J.10
-
21
-
-
0001661176
-
Cloning of the cDNA for the human β1-adrenergic receptor
-
Frielle T. S., Collins S., Daniel K. W., Caron M. G., Lefkowitz R. J., Kobilka B. K. Cloning of the cDNA for the human β1-adrenergic receptor. Proc. Natl. Acad. Sci. U.S.A. 1987; 84: 7920 – 7924
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 7920-7924
-
-
Frielle, T.S.1
Collins, S.2
Daniel, K.W.3
Caron, M.G.4
Lefkowitz, R.J.5
Kobilka, B.K.6
-
22
-
-
0025344728
-
Molecular cloning and expression of the rat β1-adrenergic receptor gene
-
Machida C. A., Bunzow J. R., Searles R. P., VanTol H., Tester B., Neve K. A., Teal P., Nipper V., Civelli O. Molecular cloning and expression of the rat β1-adrenergic receptor gene. J. Biol. Chem. 1991; 265: 12960 – 12965
-
(1991)
J. Biol. Chem.
, vol.265
, pp. 12960-12965
-
-
Machida, C.A.1
Bunzow, J.R.2
Searles, R.P.3
VanTol, H.4
Tester, B.5
Neve, K.A.6
Teal, P.7
Nipper, V.8
Civelli, O.9
-
23
-
-
0029056440
-
Differences in desensitization between human β1- and β2-adrenergic receptors stably expressed in transfected hamster cells. Cellular
-
Zhou X.-M., Pak M., Wang Z., Fishman P. H. Differences in desensitization between human β1- and β2-adrenergic receptors stably expressed in transfected hamster cells. Cellular. Signalling 1995; 7: 207 – 217
-
(1995)
Signalling
, vol.7
, pp. 207-217
-
-
Zhou, X.-M.1
Pak, M.2
Wang, Z.3
Fishman, P.H.4
-
24
-
-
0025883303
-
Desensitization of the human β1-adrenergic receptor: involvement of the cyclic AMP-dependent but not a receptor-specific protein kinase
-
Zhou X.-M., Fishman P. H. Desensitization of the human β1-adrenergic receptor: involvement of the cyclic AMP-dependent but not a receptor-specific protein kinase. J. Biol. Chem. 1991; 266: 7462 – 7468
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 7462-7468
-
-
Zhou, X.-M.1
Fishman, P.H.2
-
25
-
-
0026021807
-
Characterization and regulation of β1-adrenergic receptors in a human neuro-epithelioma cell line
-
Fishman P. H., Nussbaum E., Duman R. S. Characterization and regulation of β1-adrenergic receptors in a human neuro-epithelioma cell line. J. Neurochem. 1991; 56: 596 – 602
-
(1991)
J. Neurochem.
, vol.56
, pp. 596-602
-
-
Fishman, P.H.1
Nussbaum, E.2
Duman, R.S.3
-
26
-
-
0028068432
-
Independent and coordinate regulation of β1- and β2-adrenergic receptors in rat C6 glioma cells
-
Fishman P. H., Miller T., Curran P. K., Feussner G. K. Independent and coordinate regulation of β1- and β2-adrenergic receptors in rat C6 glioma cells. J. Receptor Res. 1994; 14: 281 – 296
-
(1994)
J. Receptor Res.
, vol.14
, pp. 281-296
-
-
Fishman, P.H.1
Miller, T.2
Curran, P.K.3
Feussner, G.K.4
-
27
-
-
0021737396
-
Desensitization of catechol-amine-stimulated adenylate cyclase and down-regulation of beta-adrenergic receptors in rat glioma C6 cells: role of cyclic AMP and protein synthesis
-
Zaremba T. G., Fishman P. H. Desensitization of catechol-amine-stimulated adenylate cyclase and down-regulation of beta-adrenergic receptors in rat glioma C6 cells: role of cyclic AMP and protein synthesis. Mol. Pharmacol. 1984; 26: 206 – 213
-
(1984)
Mol. Pharmacol.
, vol.26
, pp. 206-213
-
-
Zaremba, T.G.1
Fishman, P.H.2
-
28
-
-
0023637429
-
The role of a low β1-adrenoceptor selectivity of [3H]CGP-12177 for resolving subtype-selectivity of competitive ligands
-
Nanoff C., Freissmuth M., Schβtz W. The role of a low β1-adrenoceptor selectivity of [3H]CGP-12177 for resolving subtype-selectivity of competitive ligands. Naunyn Schmiedeberg's Arch. Pharmacol. 1987; 336: 519 – 525
-
(1987)
Naunyn Schmiedeberg's Arch. Pharmacol.
, vol.336
, pp. 519-525
-
-
Nanoff, C.1
Freissmuth, M.2
Schβtz, W.3
-
29
-
-
0022017322
-
(-)-S-[3H]CGP-12177 and its use to determine the rate constants of unlabeled β-adrenergic antagonists
-
Affolter H., Hertel C., Jaeggi K., Portenier M., Staehlin M. (-)-S-[3H]CGP-12177 and its use to determine the rate constants of unlabeled β-adrenergic antagonists. Proc. Natl. Acad. Sci. USA 1985; 83: 925 – 929
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 925-929
-
-
Affolter, H.1
Hertel, C.2
Jaeggi, K.3
Portenier, M.4
Staehlin, M.5
-
30
-
-
0027283546
-
Partial agonist, full agonist, antagonists: dilemmas of definition
-
Hoyer D., Boddeke H. W.G. M. Partial agonist, full agonist, antagonists: dilemmas of definition. Trends Pharmacol. Sci. 1993; 14: 270 – 275
-
(1993)
Trends Pharmacol. Sci.
, vol.14
, pp. 270-275
-
-
Hoyer, D.1
Boddeke, H.W.G.M.2
-
31
-
-
0028030774
-
Dual signaling potential is common among Gs-coupled receptors and dependent on receptor density
-
Zhu X., Gilbert S., Birnbaumer M., Birmbaumer L. Dual signaling potential is common among Gs-coupled receptors and dependent on receptor density. Mol. Pharmacol. 1994; 46: 460 – 469
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 460-469
-
-
Zhu, X.1
Gilbert, S.2
Birnbaumer, M.3
Birmbaumer, L.4
-
32
-
-
0029061611
-
Agonist-receptor efficacy I: mechanisms of efficacy and receptor promiscuity
-
Kenakin T. P. Agonist-receptor efficacy I: mechanisms of efficacy and receptor promiscuity. Trends Pharmacol. Sci. 1995; 16: 188 – 192
-
(1995)
Trends Pharmacol. Sci.
, vol.16
, pp. 188-192
-
-
Kenakin, T.P.1
-
33
-
-
0029054965
-
Agonist-receptor efficacy I: agonist trafficking of receptor signals
-
Kenakin T. P. Agonist-receptor efficacy I: agonist trafficking of receptor signals. Trends Pharmacol. Sci. 1995; 16: 232 – 238
-
(1995)
Trends Pharmacol. Sci.
, vol.16
, pp. 232-238
-
-
Kenakin, T.P.1
-
34
-
-
0027732228
-
Close reciprocal regulation of β1- and β2-adrenergic receptors by dexamethasone in C6glioma cells: effects on catecholamine responsiveness
-
Zhong H., Minneman K. P. Close reciprocal regulation of β1- and β2-adrenergic receptors by dexamethasone in C6glioma cells: effects on catecholamine responsiveness. Mol. Pharmacol. 1993; 44: 1085 – 1093
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 1085-1093
-
-
Zhong, H.1
Minneman, K.P.2
-
35
-
-
0025174187
-
Amplification of cyclic AMP generation reveals agonistic effects of certain β-adrenergic antagonists
-
Jasper J. R., Michel M. C., Insel P. A. Amplification of cyclic AMP generation reveals agonistic effects of certain β-adrenergic antagonists. Mol. Pharmacol. 1990; 37: 44 – 49
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 44-49
-
-
Jasper, J.R.1
Michel, M.C.2
Insel, P.A.3
-
36
-
-
0023906198
-
The β2-adrenergic receptors of human epidermoid carcinoma cells bear two different types of oligosaccharides which influence expression on the cell surface
-
Cervantes-Olivier P., Delavier-Klutchko C., Durieu-Trautmann O., Kaveri S., Desmandril M., Strosberg A. D. The β2-adrenergic receptors of human epidermoid carcinoma cells bear two different types of oligosaccharides which influence expression on the cell surface. Biochem. J. 1988; 250: 133 – 143
-
(1988)
Biochem. J.
, vol.250
, pp. 133-143
-
-
Cervantes-Olivier, P.1
Delavier-Klutchko, C.2
Durieu-Trautmann, O.3
Kaveri, S.4
Desmandril, M.5
Strosberg, A.D.6
-
37
-
-
0023930678
-
Role of glycosylation for β2-adrenoceptor function in A431 cells
-
Boege F., Ward M., Jβrss R., Hekman M., Helmreich E. J. M. Role of glycosylation for β2-adrenoceptor function in A431 cells. J. Biol. Chem. 1988; 263: 9040 – 9049
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 9040-9049
-
-
Boege, F.1
Ward, M.2
Jβrss, R.3
Hekman, M.4
Helmreich, E.J.M.5
-
38
-
-
0024544232
-
Palmitoylation of the human β2-adrenergic receptor. Mutation of Cys341in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor
-
O'Dowd B. F., Hnatowich M., Caron M. G., Lefkowitz R. J., Bouvier M. Palmitoylation of the human β2-adrenergic receptor. Mutation of Cys341in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. J. Biol. Chem. 1989; 264: 7564 – 7569
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 7564-7569
-
-
O'Dowd, B.F.1
Hnatowich, M.2
Caron, M.G.3
Lefkowitz, R.J.4
Bouvier, M.5
-
39
-
-
0021194782
-
Activation of the inhibitory GTP-binding protein of adenylate cyclase, G1by β-adrenergic receptors in reconstituted phsopholipids vesicles
-
Asano T., Katada T., Gilman A. G., Ross E. M. Activation of the inhibitory GTP-binding protein of adenylate cyclase, G1by β-adrenergic receptors in reconstituted phsopholipids vesicles. J. Biol. Chem. 1984; 259: 9351 – 9354
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 9351-9354
-
-
Asano, T.1
Katada, T.2
Gilman, A.G.3
Ross, E.M.4
-
40
-
-
0018826593
-
-
Mallorga P., Tallman J. F., Henneberry R. C., Hirata F., Strittmatter W. T., Axelrod J. Proc. Natl. Acad. Sci. USA 1980; 77: 1341 – 1345
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 1341-1345
-
-
Mallorga, P.1
Tallman, J.F.2
Henneberry, R.C.3
Hirata, F.4
Strittmatter, W.T.5
Axelrod, J.6
-
41
-
-
0019137579
-
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor
-
DeLean A., Stadel J. M., Lefkowitz R. J. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor. J. Biol. Chem. 1980; 255: 7108 – 7117
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 7108-7117
-
-
DeLean, A.1
Stadel, J.M.2
Lefkowitz, R.J.3
-
42
-
-
0027513982
-
A mutation-induced activated state of the β2-adrenergic receptor. Extending the ternary complex model
-
Samama P., Cotecchia S., Costa T., Lefkowitz R. J. A mutation-induced activated state of the β2-adrenergic receptor. Extending the ternary complex model. J. Biol. Chem. 1993; 268: 4625 – 4636
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 4625-4636
-
-
Samama, P.1
Cotecchia, S.2
Costa, T.3
Lefkowitz, R.J.4
-
43
-
-
0028350901
-
Inverse agonist activity of β-adrenergic antagonists
-
Chidiac P., Hebert T. E., Valiquette M., Dennis M., Bouvier M. Inverse agonist activity of β-adrenergic antagonists. Mol. Pharmacol. 1994; 45: 490 – 499
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 490-499
-
-
Chidiac, P.1
Hebert, T.E.2
Valiquette, M.3
Dennis, M.4
Bouvier, M.5
-
44
-
-
0027936892
-
Membrane organization in G-protein mechanisms
-
Neubig R. R. Membrane organization in G-protein mechanisms. FASEB J. 1994; 8: 939 – 946
-
(1994)
FASEB J.
, vol.8
, pp. 939-946
-
-
Neubig, R.R.1
|