-
2
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA: The retinoblastoma protein and cell cycle control. Cell 1995, 81:323-330
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
3
-
-
0030845187
-
Differential interaction of the cyclin-dependent kinase (CDK) inhibitor p27(Kip1) with cyclin A-Cdk2 and cyclin D2-Cdk4
-
DOI 10.1074/jbc.272.41.25863
-
Blain SW, Montalvo E, Massague J: Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4. J Biol Chem 1997, 272:25863-25872 (Pubitemid 27438911)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.41
, pp. 25863-25872
-
-
Blain, S.W.1
Montalvo, E.2
Massague, J.3
-
4
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr CJ, McCormick F: The RB and p53 pathways in cancer. Cancer Cell 2002, 2:103-112
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
5
-
-
5544308320
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr CJ, Roberts JM: CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999, 10:1491-1502
-
(1999)
Genes Dev
, vol.10
, pp. 1491-1502
-
-
Sherr, C.J.1
Roberts, J.M.2
-
6
-
-
0028181760
-
Identification of G1 kinase activity for cdk6, a novel cyclin D partner
-
Meyerson M, Harlow E: Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Mol Cell Biol 1994, 14:2077-2086
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2077-2086
-
-
Meyerson, M.1
Harlow, E.2
-
7
-
-
0029066658
-
Regulation of synthesis and activity of the PLSTIRE protein (cyclin-dependent kinase 6 (cdk6)), a major cyclin D-associated cdk4 homologue in normal human T lymphocytes
-
Lucas JJ, Szepesi A, Modiano JF, Domenico J, Gelfand EW: Regulation of synthesis and activity of the PLSTIRE protein (cyclin-dependent kinase 6 (cdk6)), a major cyclin D-associated cdk4 homologue in normal human T lymphocytes. J Immunol 1995, 154:6275-6284
-
(1995)
J Immunol
, vol.154
, pp. 6275-6284
-
-
Lucas, J.J.1
Szepesi, A.2
Modiano, J.F.3
Domenico, J.4
Gelfand, E.W.5
-
8
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
Malumbres M, Sotillo R, Santamaria D, Galan J, Cerezo A, Ortega S, Dubus P, Barbacid M: Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 2004, 118:493-504
-
(2004)
Cell
, vol.118
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaria, D.3
Galan, J.4
Cerezo, A.5
Ortega, S.6
Dubus, P.7
Barbacid, M.8
-
9
-
-
59149089409
-
A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis
-
Hu MG, Deshpande A, Enos M, Mao D, Hinds EA, Hu GF, Chang R, Guo Z, Dose M, Mao C, Tsichlis PN, Gounari F, Hinds PW: A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis. Cancer Res 2009, 69:810-818
-
(2009)
Cancer Res
, vol.69
, pp. 810-818
-
-
Hu, M.G.1
Deshpande, A.2
Enos, M.3
Mao, D.4
Hinds, E.A.5
Hu, G.F.6
Chang, R.7
Guo, Z.8
Dose, M.9
Mao, C.10
Tsichlis, P.N.11
Gounari, F.12
Hinds, P.W.13
-
10
-
-
67651233668
-
Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation
-
Bockstaele L, Bisteau X, Paternot S, Roger PP: Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation. Mol Cell Biol 2009, 29:4188-4200
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4188-4200
-
-
Bockstaele, L.1
Bisteau, X.2
Paternot, S.3
Roger, P.P.4
-
11
-
-
18244402890
-
Preferences for phosphorylation sites in the retinoblastoma protein of D-type cyclin-dependent kinases. Cdk4 and Cdk6, in vitro
-
Takaki T, Fukasawa K, Suzuki-Takahashi I, Semba K, Kitagawa M, Taya Y, Hirai H: Preferences for phosphorylation sites in the retinoblastoma protein of D-type cyclin-dependent kinases. Cdk4 and Cdk6, in vitro. J Biochem 2005, 137:381-386
-
(2005)
J Biochem
, vol.137
, pp. 381-386
-
-
Takaki, T.1
Fukasawa, K.2
Suzuki-Takahashi, I.3
Semba, K.4
Kitagawa, M.5
Taya, Y.6
Hirai, H.7
-
12
-
-
0033569748
-
cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domain
-
Grossel MJ, Baker GL, Hinds PW: cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domain. J Biol Chem 1999, 274:29960-29967
-
(1999)
J Biol Chem
, vol.274
, pp. 29960-29967
-
-
Grossel, M.J.1
Baker, G.L.2
Hinds, P.W.3
-
13
-
-
0038503565
-
Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes
-
Ericson KK, Krull D, Slomiany P, Grossel MJ: Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes. Mol Cancer Res 2003, 1:654-664 (Pubitemid 36870518)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.9
, pp. 654-664
-
-
Ericson, K.K.1
Krull, D.2
Slomiany, P.3
Grossel, M.J.4
-
14
-
-
0038375546
-
CDK6 blocks differentiation: Coupling cell proliferation to the block to differentiation in leukemic cells
-
Matushansky I, Radparvar F, Skoultchi AI: CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells. Oncogene 2003, 22:4143-4149
-
(2003)
Oncogene
, vol.22
, pp. 4143-4149
-
-
Matushansky, I.1
Radparvar, F.2
Skoultchi, A.I.3
-
15
-
-
3242711209
-
Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6
-
Ogasawara T, Kawaguchi H, Jinno S, Hoshi K, Itaka K, Takato T, Nakamura K, Okayama H: Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6. Mol Cell Biol 2004, 24:6560-6568
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6560-6568
-
-
Ogasawara, T.1
Kawaguchi, H.2
Jinno, S.3
Hoshi, K.4
Itaka, K.5
Takato, T.6
Nakamura, K.7
Okayama, H.8
-
16
-
-
16544395502
-
Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6)
-
Ogasawara T, Katagiri M, Yamamoto A, Hoshi K, Takato T, Nakamura K, Tanaka S, Okayama H, Kawaguchi H: Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6). J Bone Miner Res 2004, 19:1128-1136
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1128-1136
-
-
Ogasawara, T.1
Katagiri, M.2
Yamamoto, A.3
Hoshi, K.4
Takato, T.5
Nakamura, K.6
Tanaka, S.7
Okayama, H.8
Kawaguchi, H.9
-
17
-
-
0035942498
-
Accumulation of high levels of the p53 and p130 growth-suppressing proteins in cell lines stably over-expressing cyclin-dependent kinase 6 (cdk6)
-
DOI 10.1038/sj.onc.1204396
-
Nagasawa M, Gelfand EW, Lucas JJ: Accumulation of high levels of the p53 and p130 growth-suppressing proteins in cell lines stably over-expressing cyclin-dependent kinase 6 (cdk6). Oncogene 2001, 20:2889-2899 (Pubitemid 33027756)
-
(2001)
Oncogene
, vol.20
, Issue.23
, pp. 2889-2899
-
-
Nagasawa, M.1
Gelfand, E.W.2
Lucas, J.J.3
-
18
-
-
0026611745
-
Regulation of synthesis of p34cdc2 and its homologues and their relationship to p110Rb phosphorylation during cell cycle progression of normal human T cells
-
Lucas JJ, Terada N, Szepesi A, Gelfand EW: Regulation of synthesis of p34cdc2 and its homologues and their relationship to p110Rb phosphorylation during cell cycle progression of normal human T cells. J Immunol 1992, 148:1804-1811
-
(1992)
J Immunol
, vol.148
, pp. 1804-1811
-
-
Lucas, J.J.1
Terada, N.2
Szepesi, A.3
Gelfand, E.W.4
-
19
-
-
0028863466
-
Differential regulation of the synthesis and activity of the major cyclin-dependent kinases, p34cdc2, p33cdk2, and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes
-
Lucas JJ, Szepesi A, Domenico J, Tordai A, Terada N, Gelfand EW: Differential regulation of the synthesis and activity of the major cyclin-dependent kinases, p34cdc2, p33cdk2, and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes. J Cell Physiol 1995, 165:406-416
-
(1995)
J Cell Physiol
, vol.165
, pp. 406-416
-
-
Lucas, J.J.1
Szepesi, A.2
Domenico, J.3
Tordai, A.4
Terada, N.5
Gelfand, E.W.6
-
20
-
-
0030982897
-
Cyclin-dependent kinase 6 (CDK6) amplification in human gliomas identified using two-dimensional separation of genomic DNA
-
Costello JF, Plass C, Arap W, Chapman VM, Held WA, Berger MS, Su Huang HJ, Cavenee WK: Cyclin-dependent kinase 6 (CDK6) amplification in human gliomas identified using two-dimensional separation of genomic DNA. Cancer Res 1997, 57:1250-1254
-
(1997)
Cancer Res
, vol.57
, pp. 1250-1254
-
-
Costello, J.F.1
Plass, C.2
Arap, W.3
Chapman, V.M.4
Held, W.A.5
Berger, M.S.6
Su Huang, H.J.7
Cavenee, W.K.8
-
21
-
-
0029736653
-
Human glioblastomas with no alterations of the CDKN2A (p16INK4A. MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene
-
Ichimura K, Schmidt EE, Goike HM, Collins VP: Human glioblastomas with no alterations of the CDKN2A (p16INK4A. MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene. Oncogene 1996, 13:1065-1072
-
(1996)
Oncogene
, vol.13
, pp. 1065-1072
-
-
Ichimura, K.1
Schmidt, E.E.2
Goike, H.M.3
Collins, V.P.4
-
22
-
-
0034135920
-
Expression of p19INK4d. CDK4, CDK6 in glioblastoma multiforme
-
Lam PY, Di Tomaso E, Ng HK, Pang JC, Roussel MF, Hjelm NM: Expression of p19INK4d. CDK4, CDK6 in glioblastoma multiforme. Br J Neurosurg 2000, 14:28-32
-
(2000)
Br J Neurosurg
, vol.14
, pp. 28-32
-
-
Lam, P.Y.1
Di Tomaso, E.2
Ng, H.K.3
Pang, J.C.4
Roussel, M.F.5
Hjelm, N.M.6
-
23
-
-
0028652269
-
CDKN2 (p16/ MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
-
Schmidt EE, Ichimura K, Reifenberger G, Collins VP: CDKN2 (p16/ MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res 1994, 54:6321-6324
-
(1994)
Cancer Res
, vol.54
, pp. 6321-6324
-
-
Schmidt, E.E.1
Ichimura, K.2
Reifenberger, G.3
Collins, V.P.4
-
24
-
-
0029664339
-
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
-
Zuo L, Weger J, Yang Q, Goldstein AM, Tucker MA, Walker GJ, Hayward N, Dracopoli NC: Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma. Nat Genet 1996, 12:97-99
-
(1996)
Nat Genet
, vol.12
, pp. 97-99
-
-
Zuo, L.1
Weger, J.2
Yang, Q.3
Goldstein, A.M.4
Tucker, M.A.5
Walker, G.J.6
Hayward, N.7
Dracopoli, N.C.8
-
25
-
-
0028978274
-
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
-
Wölfel T, Hauer M, Schneider J, Serrano M, Wölfel C, Klehmann-Hieb E, De Plaen E, Hankeln T, Meyer zum Büschenfelde KH, Beach D: A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science 1995, 269:1281-1284
-
(1995)
Science
, vol.269
, pp. 1281-1284
-
-
Wölfel, T.1
Hauer, M.2
Schneider, J.3
Serrano, M.4
Wölfel, C.5
Klehmann-Hieb, E.6
De Plaen, E.7
Hankeln, T.8
Meyer Zum Büschenfelde, K.H.9
Beach, D.10
-
26
-
-
0030916439
-
Elevated activity of cyclin-dependent kinase 6 in human squamous cell carcinoma lines
-
Timmermann S, Hinds PW, Munger K: Elevated activity of cyclin-dependent kinase 6 in human squamous cell carcinoma lines. Cell Growth Differ 1997, 8:361-370
-
(1997)
Cell Growth Differ
, vol.8
, pp. 361-370
-
-
Timmermann, S.1
Hinds, P.W.2
Munger, K.3
-
27
-
-
0036178622
-
Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity
-
Piboonniyom SO, Timmermann S, Hinds P, Munger K: Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity. Oral Oncol 2002, 38:179-186
-
(2002)
Oral Oncol
, vol.38
, pp. 179-186
-
-
Piboonniyom, S.O.1
Timmermann, S.2
Hinds, P.3
Munger, K.4
-
28
-
-
0032525883
-
Disruption of the cyclin D/cyclin-dependent kinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma
-
Easton J, Wei T, Lahti JM, Kidd VJ: Disruption of the cyclin D/cyclin-dependent kinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma. Cancer Res 1998, 58:2624-2632
-
(1998)
Cancer Res
, vol.58
, pp. 2624-2632
-
-
Easton, J.1
Wei, T.2
Lahti, J.M.3
Kidd, V.J.4
-
29
-
-
0030611070
-
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms
-
Zhang S-Y, Liu S-C, Goodrow T, Morris R, Klein-Szanto AJP: Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms. Mol Carcinog 1997, 18:142-152
-
(1997)
Mol Carcinog
, vol.18
, pp. 142-152
-
-
Zhang, S.-Y.1
Liu, S.-C.2
Goodrow, T.3
Morris, R.4
Klein-Szanto, A.J.P.5
-
30
-
-
0032578864
-
Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin
-
Rodriguez-Puebla ML, LaCava M, Gimenez-Conti IB, Johnson DG, Conti CJ: Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin. Oncogene 1998, 17:2251-2258 (Pubitemid 28515377)
-
(1998)
Oncogene
, vol.17
, Issue.17
, pp. 2251-2258
-
-
Rodriguez-Puebla, M.L.1
LaCava, M.2
Gimenez-Conti, I.B.3
Johnson, D.G.4
Conti, C.J.5
-
31
-
-
0032789831
-
Cyclin D1 overexpression in mouse epidermis increases cyclin-dependent kinase activity and cell proliferation in vivo but does not affect skin tumor development
-
Rodriguez-Puebla ML, LaCava M, Conti CJ: Cyclin D1 overexpression in mouse epidermis increases cyclin-dependent kinase activity and cell proliferation in vivo but does not affect skin tumor development. Cell Growth Differ 1999, 10:467-472
-
(1999)
Cell Growth Differ
, vol.10
, pp. 467-472
-
-
Rodriguez-Puebla, M.L.1
LaCava, M.2
Conti, C.J.3
-
32
-
-
0036965836
-
Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation
-
Rodriguez-Puebla ML, Miliani de Marval PL, LaCava M, Moons DS, Kiyokawa H, Conti CJ: Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation. Am J Pathol 2002, 161:405-411
-
(2002)
Am J Pathol
, vol.161
, pp. 405-411
-
-
Rodriguez-Puebla, M.L.1
Miliani De Marval, P.L.2
LaCava, M.3
Moons, D.S.4
Kiyokawa, H.5
Conti, C.J.6
-
33
-
-
1842429910
-
Enhanced malignant tumorigenesis in Cdk4 transgenic mice
-
DOI 10.1038/sj.onc.1207309
-
Miliani de Marval PL, Macias E, Conti CJ, Rodriguez-Puebla MLR: Enhanced malignant tumorigenesis in Cdk4 transgenic miceR. Oncogene 2004, 23R: 1863-1873 (Pubitemid 38445412)
-
(2004)
Oncogene
, vol.23
, Issue.10
, pp. 1863-1873
-
-
De Miliani, M.P.L.1
Macias, E.2
Conti, C.J.3
Rodriguez-Puebla, M.L.4
-
34
-
-
65749120029
-
Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)
-
Rojas P, Benavides F, Blando J, Perez C, Cardenas K, Richie E, Knudsen ES, Johnson DG, Senderowicz AM, Rodriguez-Puebla ML, Conti CJ: Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b). Mol Carcinog 2009, 48:508-516
-
(2009)
Mol Carcinog
, vol.48
, pp. 508-516
-
-
Rojas, P.1
Benavides, F.2
Blando, J.3
Perez, C.4
Cardenas, K.5
Richie, E.6
Knudsen, E.S.7
Johnson, D.G.8
Senderowicz, A.M.9
Rodriguez-Puebla, M.L.10
Conti, C.J.11
-
35
-
-
35448958408
-
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis
-
Macias E, Kim Y, Miliani de Marval PL, Klein-Szanto A, Rodriguez- Puebla ML: Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis. Cancer Res 2007, 67:9713-9720
-
(2007)
Cancer Res
, vol.67
, pp. 9713-9720
-
-
Macias, E.1
Kim, Y.2
Miliani De Marval, P.L.3
Klein-Szanto, A.4
Rodriguez- Puebla, M.L.5
-
36
-
-
48749133336
-
CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development
-
Macias E, Miliani de Marval PL, De Siervi A, Conti CJ, Senderowicz AM, Rodriguez-Puebla ML: CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development. Am J Pathol 2008, 173:526-535
-
(2008)
Am J Pathol
, vol.173
, pp. 526-535
-
-
Macias, E.1
Miliani De Marval, P.L.2
De Siervi, A.3
Conti, C.J.4
Senderowicz, A.M.5
Rodriguez-Puebla, M.L.6
-
37
-
-
0035404133
-
Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis
-
Miliani de Marval PL, Gimenez-Conti IB, LaCava M, Martinez LA, Conti CJ, Rodriguez-Puebla ML: Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis. Am J Pathol 2001, 159:369-379
-
(2001)
Am J Pathol
, vol.159
, pp. 369-379
-
-
Miliani De Marval, P.L.1
Gimenez-Conti, I.B.2
LaCava, M.3
Martinez, L.A.4
Conti, C.J.5
Rodriguez-Puebla, M.L.6
-
38
-
-
4344631708
-
Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues
-
Miliani de Marval PL, Macias E, Rounbehler R, Sicinski P, Kiyokawa H, Johnson DG, Conti CJ, Rodriguez-Puebla ML:Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. Mol Cell Biol 2004, 24:7538-7547
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7538-7547
-
-
Miliani De Marval, P.L.1
Macias, E.2
Rounbehler, R.3
Sicinski, P.4
Kiyokawa, H.5
Johnson, D.G.6
Conti, C.J.7
Rodriguez-Puebla, M.L.8
-
39
-
-
0034495082
-
Cyclin D2 overexpression in transgenic mice induces thymic and epidermal hyperplasia whereas cyclin D3 expression results only in epidermal hyperplasia
-
Rodriguez-Puebla ML, LaCava M, Miliani De Marval PL, Jorcano JL, Richie ER, Conti CJ: Cyclin D2 overexpression in transgenic mice induces thymic and epidermal hyperplasia whereas cyclin D3 expression results only in epidermal hyperplasia. Am J Pathol 2000, 157:1039-1050
-
(2000)
Am J Pathol
, vol.157
, pp. 1039-1050
-
-
Rodriguez-Puebla, M.L.1
LaCava, M.2
Miliani De Marval, P.L.3
Jorcano, J.L.4
Richie, E.R.5
Conti, C.J.6
-
40
-
-
33947221512
-
Cyclin D2 and cyclin D3 play opposite roles in mouse skin carcinogenesis
-
Rojas P, Cadenas MB, Lin PC, Benavides F, Conti CJ, Rodriguez- Puebla ML: Cyclin D2 and cyclin D3 play opposite roles in mouse skin carcinogenesis. Oncogene 2007, 26:1723-1730
-
(2007)
Oncogene
, vol.26
, pp. 1723-1730
-
-
Rojas, P.1
Cadenas, M.B.2
Lin, P.C.3
Benavides, F.4
Conti, C.J.5
Rodriguez- Puebla, M.L.6
-
41
-
-
30344470210
-
Requirement for CDK4 kinase function in breast cancer
-
Yu Q, Sicinska E, Geng Y, Ahnstrom M, Zagozdzon A, Kong Y, Gardner H, Kiyokawa H, Harris LN, Stal O, Sicinski P: Requirement for CDK4 kinase function in breast cancer. Cancer Cell 2006, 9:23-32
-
(2006)
Cancer Cell
, vol.9
, pp. 23-32
-
-
Yu, Q.1
Sicinska, E.2
Geng, Y.3
Ahnstrom, M.4
Zagozdzon, A.5
Kong, Y.6
Gardner, H.7
Kiyokawa, H.8
Harris, L.N.9
Stal, O.10
Sicinski, P.11
-
42
-
-
0037112178
-
Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence
-
Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H: Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes Dev 2002, 16:2923-2934
-
(2002)
Genes Dev
, vol.16
, pp. 2923-2934
-
-
Zou, X.1
Ray, D.2
Aziyu, A.3
Christov, K.4
Boiko, A.D.5
Gudkov, A.V.6
Kiyokawa, H.7
-
43
-
-
0027973880
-
Sequences 5' of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development
-
DOI 10.1007/s002580050065
-
Ramirez A, Bravo A, Jorcano J, Vidal M: Sequences 5′ of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development. Differentiation 1994, 58:53-64 (Pubitemid 24361127)
-
(1994)
Differentiation
, vol.58
, Issue.1
, pp. 53-64
-
-
Ramirez, A.1
Bravo, A.2
Jorcano, J.L.3
Vidal, M.4
-
44
-
-
0031964722
-
Synchronized proliferation induced by 12-O-tetradecanoylphorbol- 13-acetate treatment of mouse skin: An in vivo model for cell cycle regulation
-
Rodriguez-Puebla ML, Robles AI, Johnson DG, LaCava M, Conti CJ: Synchronized proliferation induced by 12-O-tetradecanoylphorbol- 13-acetate treatment of mouse skin: an in vivo model for cell cycle regulation. Cell Growth Differ 1998, 9:31-39
-
(1998)
Cell Growth Differ
, vol.9
, pp. 31-39
-
-
Rodriguez-Puebla, M.L.1
Robles, A.I.2
Johnson, D.G.3
LaCava, M.4
Conti, C.J.5
-
45
-
-
28644451449
-
Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
-
Ito M, Liu Y, Yang Z, Nguyen J, Liang F, Morris RJ, Cotsarelis G: Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 2005, 11:1351-1354
-
(2005)
Nat Med
, vol.11
, pp. 1351-1354
-
-
Ito, M.1
Liu, Y.2
Yang, Z.3
Nguyen, J.4
Liang, F.5
Morris, R.J.6
Cotsarelis, G.7
-
46
-
-
0020368610
-
Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies
-
Woodcock-Mitchell J, Eichner R, Nelson WG, Sun T: Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol 1982, 95:580-588
-
(1982)
J Cell Biol
, vol.95
, pp. 580-588
-
-
Woodcock-Mitchell, J.1
Eichner, R.2
Nelson, W.G.3
Sun, T.4
-
47
-
-
0345583659
-
Keratin gene expression in mouse epidermis and cultured epidermal cells
-
Roop D, Hawley-Nelson P, Cheng CK, Yuspa SH: Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A 1983, 80:716-720
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 716-720
-
-
Roop, D.1
Hawley-Nelson, P.2
Cheng, C.K.3
Yuspa, S.H.4
-
48
-
-
0026346885
-
Alterations of the p53 tumor suppressor gene during mouse skin tumor progression
-
Ruggeri B, Caamano J, Goodrow T, DiRado M, Bianchi A, Trono D, Conti CJ, Klein-Szanto AJ: Alterations of the p53 tumor suppressor gene during mouse skin tumor progression. Cancer Res 1991, 51:6615-6621
-
(1991)
Cancer Res
, vol.51
, pp. 6615-6621
-
-
Ruggeri, B.1
Caamano, J.2
Goodrow, T.3
DiRado, M.4
Bianchi, A.5
Trono, D.6
Conti, C.J.7
Klein-Szanto, A.J.8
-
49
-
-
0032937751
-
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
-
Rane SG, Dubus P, Mettus RV, Galbreath EJ, Boden G, Reddy EP, Barbacid M: Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia. Nat Genet 1999, 22:44-52
-
(1999)
Nat Genet
, vol.22
, pp. 44-52
-
-
Rane, S.G.1
Dubus, P.2
Mettus, R.V.3
Galbreath, E.J.4
Boden, G.5
Reddy, E.P.6
Barbacid, M.7
-
50
-
-
0032849353
-
Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity
-
Tsutsui T, Hesabi B, Moons DS, Pandolfi PP, Hansel KS, Koff A, Kiyokawa H: Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Mol Cell Biol 1999, 19:7011-7019
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7011-7019
-
-
Tsutsui, T.1
Hesabi, B.2
Moons, D.S.3
Pandolfi, P.P.4
Hansel, K.S.5
Koff, A.6
Kiyokawa, H.7
-
51
-
-
0033559980
-
The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis
-
Hakem A, Sasaki T, Kozieradzki I, Penninger JM: The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis. J Exp Med 1999, 189:957-968
-
(1999)
J Exp Med
, vol.189
, pp. 957-968
-
-
Hakem, A.1
Sasaki, T.2
Kozieradzki, I.3
Penninger, J.M.4
-
52
-
-
0345425059
-
Cdc2 and Cdk2 kinase activated by transforming growth factor-beta1 trigger apoptosis through the phosphorylation of retinoblastoma protein in FaO hepatoma cells
-
Choi KS, Eom YW, Kang Y, Ha MJ, Rhee H, Yoon JW, Kim SJ: Cdc2 and Cdk2 kinase activated by transforming growth factor-beta1 trigger apoptosis through the phosphorylation of retinoblastoma protein in FaO hepatoma cells. J Biol Chem 1999, 274:31775-31783 (Pubitemid 129503760)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.45
, pp. 31775-31783
-
-
Choi, K.S.1
Eom, Y.W.2
Kang, Y.3
Ha, M.J.4
Rhee, H.5
Yoon, J.-W.6
Kim, S.-J.7
-
53
-
-
43149102480
-
Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis
-
Maddika S, Ande SR, Wiechec E, Hansen LL, Wesselborg S, Los M: Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis. J Cell Sci 2008, 121:979-988
-
(2008)
J Cell Sci
, vol.121
, pp. 979-988
-
-
Maddika, S.1
Ande, S.R.2
Wiechec, E.3
Hansen, L.L.4
Wesselborg, S.5
Los, M.6
-
54
-
-
0032535140
-
A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis
-
Gil-Gomez G, Berns A, Brady HJ: A link between cell cycle and cell death: bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis. EMBO J 1998, 17:7209-7218
-
(1998)
EMBO J
, vol.17
, pp. 7209-7218
-
-
Gil-Gomez, G.1
Berns, A.2
Brady, H.J.3
-
55
-
-
27544507280
-
Unexpected roles for pRb in mouse skin carcinogenesis
-
Ruiz S, Santos M, Lara MF, Segrelles C, Ballestin C, Paramio JM: Unexpected roles for pRb in mouse skin carcinogenesis. Cancer Res 2005, 65:9678-9686
-
(2005)
Cancer Res
, vol.65
, pp. 9678-9686
-
-
Ruiz, S.1
Santos, M.2
Lara, M.F.3
Segrelles, C.4
Ballestin, C.5
Paramio, J.M.6
-
56
-
-
33645285881
-
Is the loss of pRb essential for the mouse skin carcinogenesis?
-
Ruiz S, Santos M, Paramio JM: Is the loss of pRb essential for the mouse skin carcinogenesis? Cell Cycle 2006, 5:625-629
-
(2006)
Cell Cycle
, vol.5
, pp. 625-629
-
-
Ruiz, S.1
Santos, M.2
Paramio, J.M.3
-
57
-
-
34547133494
-
The C/EBP family of transcription factors: A paradigm for interaction between gene expression and proliferation control
-
Nerlov C: The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control. Trends Cell Biol 2007, 17:318-324
-
(2007)
Trends Cell Biol
, vol.17
, pp. 318-324
-
-
Nerlov, C.1
-
58
-
-
32244441908
-
From cell cycle to differentiation: An expanding role for Cdk6
-
Grossel MJ, Hinds PW: From cell cycle to differentiation: an expanding role for cdk6. Cell Cycle 2006, 5:266-270 (Pubitemid 43213495)
-
(2006)
Cell Cycle
, vol.5
, Issue.3
, pp. 266-270
-
-
Grossel, M.J.1
Hinds, P.W.2
-
59
-
-
33144460031
-
Beyond the cell cycle: A new role for Cdk6 in differentiation
-
Grossel MJ, Hinds PW: Beyond the cell cycle: a new role for Cdk6 in differentiation. J Cell Biochem 2006, 97:485-493
-
(2006)
J Cell Biochem
, vol.97
, pp. 485-493
-
-
Grossel, M.J.1
Hinds, P.W.2
-
60
-
-
34247571525
-
Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interaction
-
Fujimoto T, Anderson K, Jacobsen SE, Nishikawa SI, Nerlov C: Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interaction. EMBO J 2007, 26:2361-2370
-
(2007)
EMBO J
, vol.26
, pp. 2361-2370
-
-
Fujimoto, T.1
Anderson, K.2
Jacobsen, S.E.3
Nishikawa, S.I.4
Nerlov, C.5
-
61
-
-
77952005330
-
Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin
-
Hoi CS, Lee SE, Lu SY, McDermitt DJ, Osorio KM, Piskun CM, Peters RM, Paus R, Tumbar T: Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin. Mol Cell Biol 2010, 30:2518-2536
-
(2010)
Mol Cell Biol
, vol.30
, pp. 2518-2536
-
-
Hoi, C.S.1
Lee, S.E.2
Lu, S.Y.3
McDermitt, D.J.4
Osorio, K.M.5
Piskun, C.M.6
Peters, R.M.7
Paus, R.8
Tumbar, T.9
-
62
-
-
55949125166
-
Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage
-
Santos M, Ruiz S, Lara MF, Segrelles C, Moral M, Martinez-Cruz AB, Ballestin C, Lorz C, Garcia-Escudero R, Paramio JM: Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage. Mol Carcinog 2008, 47:815-821
-
(2008)
Mol Carcinog
, vol.47
, pp. 815-821
-
-
Santos, M.1
Ruiz, S.2
Lara, M.F.3
Segrelles, C.4
Moral, M.5
Martinez-Cruz, A.B.6
Ballestin, C.7
Lorz, C.8
Garcia-Escudero, R.9
Paramio, J.M.10
-
63
-
-
0036470433
-
Replication licensing- Defining the proliferative state?
-
Blow JJ, Hodgson B: Replication licensing- defining the proliferative state? Trends Cell Biol 2002, 12:72-78
-
(2002)
Trends Cell Biol
, vol.12
, pp. 72-78
-
-
Blow, J.J.1
Hodgson, B.2
-
64
-
-
39549110810
-
Preventing DNA over-replication: A Cdk perspective
-
Porter AC: Preventing DNA over-replication: a Cdk perspective. Cell Div 2008, 3:3
-
(2008)
Cell Div
, vol.3
, pp. 3
-
-
Porter, A.C.1
-
65
-
-
58149234010
-
Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly
-
Braden WA, McClendon AK, Knudsen ES: Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly. Oncogene 2008, 27:7083-7093
-
(2008)
Oncogene
, vol.27
, pp. 7083-7093
-
-
Braden, W.A.1
McClendon, A.K.2
Knudsen, E.S.3
-
66
-
-
33645226613
-
Cyclin D3 maintains growth-inhibitory activity of C/ EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes
-
Wang GL, Shi X, Salisbury E, Sun Y, Albrecht JH, Smith RG, Timchenko NA: Cyclin D3 maintains growth-inhibitory activity of C/ EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes. Mol Cell Biol 2006, 26:2570-2582
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2570-2582
-
-
Wang, G.L.1
Shi, X.2
Salisbury, E.3
Sun, Y.4
Albrecht, J.H.5
Smith, R.G.6
Timchenko, N.A.7
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