-
1
-
-
0027921638
-
Head and neck cancer
-
Vokes, E. E., Weichselbaum, R. R., Lippman, S. M., and Hong, W. K. Head and neck cancer. N. Engl. J. Med., 328: 184-194, 1993.
-
(1993)
N. Engl. J. Med.
, vol.328
, pp. 184-194
-
-
Vokes, E.E.1
Weichselbaum, R.R.2
Lippman, S.M.3
Hong, W.K.4
-
2
-
-
0029181393
-
Some histopathological and clinical correlations in oral squamous cell carcinoma
-
Fernandez-Martinez, J. A., Ruiz-Avila, I., Bravo, M., Ramos, M. C., Martinez-Lara, I., Urquia, M., and Gonzalez-Moles, M. A. Some histopathological and clinical correlations in oral squamous cell carcinoma. Bull. Group. Int. Rech. Sci. Stomatol. Odontol., 38: 11-15, 1995.
-
(1995)
Bull. Group. Int. Rech. Sci. Stomatol. Odontol.
, vol.38
, pp. 11-15
-
-
Fernandez-Martinez, J.A.1
Ruiz-Avila, I.2
Bravo, M.3
Ramos, M.C.4
Martinez-Lara, I.5
Urquia, M.6
Gonzalez-Moles, M.A.7
-
3
-
-
0028041859
-
p53 expression and mutations in squamous cell carcinomas of the head and neck: Expression correlates with the patients' use of tobacco and alcohol
-
Field, J. K., Zoumpourlis, V., Spandidos, D. A., and Jones, A. S. p53 expression and mutations in squamous cell carcinomas of the head and neck: expression correlates with the patients' use of tobacco and alcohol. Cancer Detect. Prev., 18: 197-208, 1994.
-
(1994)
Cancer Detect. Prev.
, vol.18
, pp. 197-208
-
-
Field, J.K.1
Zoumpourlis, V.2
Spandidos, D.A.3
Jones, A.S.4
-
4
-
-
0026637805
-
Human papillomaviruses and oral neoplasia
-
Yeudall, W. A. Human papillomaviruses and oral neoplasia. Eur. J. Cancer, 28B: 61-66, 1992.
-
(1992)
Eur. J. Cancer
, vol.28 B
, pp. 61-66
-
-
Yeudall, W.A.1
-
5
-
-
0026636412
-
Oncogenes and tumour-suppressor genes in squamous cell carcinoma of the head and neck
-
Field, J. K. Oncogenes and tumour-suppressor genes in squamous cell carcinoma of the head and neck. Eur. J. Cancer B Oral Oncol., 28B: 67-76, 1992.
-
(1992)
Eur. J. Cancer B Oral Oncol.
, vol.28 B
, pp. 67-76
-
-
Field, J.K.1
-
6
-
-
0026737285
-
Occurrence of p53 gene deletions and human papillomavirus infection in human head and neck cancer
-
Brachman, D. G., Graves, D., Vokes, E., Beckett, M., Haraf, D., Montag, A., Dunphy, E., Mick, R., Yandell, D., and Weichselbaum, R. R. Occurrence of p53 gene deletions and human papillomavirus infection in human head and neck cancer. Cancer Res., 52: 4832-4836, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 4832-4836
-
-
Brachman, D.G.1
Graves, D.2
Vokes, E.3
Beckett, M.4
Haraf, D.5
Montag, A.6
Dunphy, E.7
Mick, R.8
Yandell, D.9
Weichselbaum, R.R.10
-
7
-
-
0027233830
-
Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines
-
Burns, J. E., Baird, M. C., Clark, L. J., Burns, P. A., Edington, E., Chapman, C., Mitchell, R., Robertson, G., Soutar, D., and Parkinson, E. K. Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines. Br. J. Cancer, 67: 1274-1284, 1993.
-
(1993)
Br. J. Cancer
, vol.67
, pp. 1274-1284
-
-
Burns, J.E.1
Baird, M.C.2
Clark, L.J.3
Burns, P.A.4
Edington, E.5
Chapman, C.6
Mitchell, R.7
Robertson, G.8
Soutar, D.9
Parkinson, E.K.10
-
8
-
-
0027715215
-
p53 alterations in human squamous cell carcinomas and carcinoma cell lines
-
Caamano, J., Zhang, S. Y., Rosvold, E. A., Bauer, B., and Klein-Szanto, A. J. P. p53 alterations in human squamous cell carcinomas and carcinoma cell lines. Am. J. Pathol., 142: 1131-1139, 1993.
-
(1993)
Am. J. Pathol.
, vol.142
, pp. 1131-1139
-
-
Caamano, J.1
Zhang, S.Y.2
Rosvold, E.A.3
Bauer, B.4
Klein-Szanto, A.J.P.5
-
9
-
-
0027331855
-
State of p53, RB and DCC tumor suppressor genes in human oral cancer cell lines
-
Kim, M. S., Li, S., Bertolami, C. N., Cherrick, H. M., and Park, N. State of p53, RB and DCC tumor suppressor genes in human oral cancer cell lines. Anticancer Res., 13: 1405-1414, 1993.
-
(1993)
Anticancer Res.
, vol.13
, pp. 1405-1414
-
-
Kim, M.S.1
Li, S.2
Bertolami, C.N.3
Cherrick, H.M.4
Park, N.5
-
10
-
-
0028389802
-
Loss of heterozygosity involving the APC gene in oral squamous cell carcinomas
-
Largey, J. S., Meltzer, S. J., Sauk, J. J., Hebert, C. A., and Archibald, D. W. Loss of heterozygosity involving the APC gene in oral squamous cell carcinomas. Oral Surg. Oral Med. Oral Pathol., 77: 260-263, 1994.
-
(1994)
Oral Surg. Oral Med. Oral Pathol.
, vol.77
, pp. 260-263
-
-
Largey, J.S.1
Meltzer, S.J.2
Sauk, J.J.3
Hebert, C.A.4
Archibald, D.W.5
-
11
-
-
0028024941
-
Abnormalities of the adenomatous polyposis coli gene in human oral squamous-cell carcinoma
-
Uzawa, K., Yoshida, H., Suzuki, H., Tanzawa, H., Shimazaki, J., Seino, S., and Sato, K. Abnormalities of the adenomatous polyposis coli gene in human oral squamous-cell carcinoma. Int. J. Cancer, 58: 814-817, 1994.
-
(1994)
Int. J. Cancer
, vol.58
, pp. 814-817
-
-
Uzawa, K.1
Yoshida, H.2
Suzuki, H.3
Tanzawa, H.4
Shimazaki, J.5
Seino, S.6
Sato, K.7
-
12
-
-
0028864747
-
Deleted in oral cancer (doc-1), a novel oral tumor suppressor gene
-
Todd, R., McBride, J., Tsuji, T., Donoff, R. B., Nagai, M., Chou, M. Y., Chiang, T., and Wong, D. T. W. Deleted in oral cancer (doc-1), a novel oral tumor suppressor gene. FASEB J., 9: 1362-1370, 1995.
-
(1995)
FASEB J.
, vol.9
, pp. 1362-1370
-
-
Todd, R.1
McBride, J.2
Tsuji, T.3
Donoff, R.B.4
Nagai, M.5
Chou, M.Y.6
Chiang, T.7
Wong, D.T.W.8
-
13
-
-
0025304297
-
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumors
-
Horowitz, J. M., Park, S-H., Bogenmann, E., Cheng, J-C., Yandell, D. W., Kaye, F., Minna, J. D., Dryja, T., and Weinberg, R. A. Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumors. Proc. Natl. Acad. Sci. USA, 87: 2775-2779, 1990.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2775-2779
-
-
Horowitz, J.M.1
Park, S.-H.2
Bogenmann, E.3
Cheng, J.-C.4
Yandell, D.W.5
Kaye, F.6
Minna, J.D.7
Dryja, T.8
Weinberg, R.A.9
-
14
-
-
0024281617
-
Inactivation of the retinoblastoma susceptibility gene in human breast cancers
-
Washington DC
-
Lee, E. Y., To, H., Shew, J. Y., Bookstein, R., Scully, P., and Lee, W. H. Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science (Washington DC), 241: 218-221, 1988.
-
(1988)
Science
, vol.241
, pp. 218-221
-
-
Lee, E.Y.1
To, H.2
Shew, J.Y.3
Bookstein, R.4
Scully, P.5
Lee, W.H.6
-
15
-
-
0028017632
-
Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma
-
Yoo, G. H., Xu, H. J., Brennan, J. A., Westra, W., Hruban, R. H., Koch, W., Benedict, W. F., and Sidransky, D. Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma. Cancer Res., 54: 4603-4606, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4603-4606
-
-
Yoo, G.H.1
Xu, H.J.2
Brennan, J.A.3
Westra, W.4
Hruban, R.H.5
Koch, W.6
Benedict, W.F.7
Sidransky, D.8
-
16
-
-
0024439444
-
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
-
Buchkovich, K., Duffy, L. A., and Harlow, E. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell, 58: 1097-1105, 1989.
-
(1989)
Cell
, vol.58
, pp. 1097-1105
-
-
Buchkovich, K.1
Duffy, L.A.2
Harlow, E.3
-
17
-
-
0024429019
-
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
-
Chen, P-L., Scully, P., Shew, J-Y., Wang, J. Y. J., and Lee, W-H. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell, 58: 1193-1198, 1989.
-
(1989)
Cell
, vol.58
, pp. 1193-1198
-
-
Chen, P.-L.1
Scully, P.2
Shew, J.-Y.3
Wang, J.Y.J.4
Lee, W.-H.5
-
18
-
-
0024418207
-
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
-
DeCaprio, J. A., Ludlow, J. W., Lynch, D., Furukawa, Y., Griffin, J., Piwnica-Worms, H., Huang, C. M., and Livingston, D. M. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell, 58: 1085-1095, 1989.
-
(1989)
Cell
, vol.58
, pp. 1085-1095
-
-
DeCaprio, J.A.1
Ludlow, J.W.2
Lynch, D.3
Furukawa, Y.4
Griffin, J.5
Piwnica-Worms, H.6
Huang, C.M.7
Livingston, D.M.8
-
19
-
-
0026567432
-
The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression
-
DeCaprio, J. A., Furukawa, Y., Ajchenbaum, F., Griffin, J. D., and Livingston, D. M. The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression. Proc. Natl. Acad. Sci. USA, 89: 1795-1798, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 1795-1798
-
-
DeCaprio, J.A.1
Furukawa, Y.2
Ajchenbaum, F.3
Griffin, J.D.4
Livingston, D.M.5
-
20
-
-
0025060176
-
The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T
-
Ludlow, J. W., Shon, J., Pipas, J. M., Livingston, D. M., and DeCaprio, J. A. The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. Cell, 60: 387-396, 1990.
-
(1990)
Cell
, vol.60
, pp. 387-396
-
-
Ludlow, J.W.1
Shon, J.2
Pipas, J.M.3
Livingston, D.M.4
DeCaprio, J.A.5
-
21
-
-
0028268284
-
D-type cyclin-dependent kinase activity in mammalian cells
-
Matsushime, H., Quelle, D. E., Shurtleff, S. A., Shibuya, M., Sherr, C. J., and Kato, J. Y. D-type cyclin-dependent kinase activity in mammalian cells. Mol. Cell. Biol., 14: 2066-2076, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2066-2076
-
-
Matsushime, H.1
Quelle, D.E.2
Shurtleff, S.A.3
Shibuya, M.4
Sherr, C.J.5
Kato, J.Y.6
-
22
-
-
0028181760
-
Identification of G(1) kinase activity for cdk6, a novel cyclin D partner
-
Meyerson, M., and Harlow, E. Identification of G(1) kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol., 14: 2077-2086, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2077-2086
-
-
Meyerson, M.1
Harlow, E.2
-
23
-
-
0027288908
-
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
-
Kato, J., Matsushime, H., Hiebert, S. W., Ewen, M. E., and Sherr, C. J. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev., 7: 331-342, 1993.
-
(1993)
Genes Dev.
, vol.7
, pp. 331-342
-
-
Kato, J.1
Matsushime, H.2
Hiebert, S.W.3
Ewen, M.E.4
Sherr, C.J.5
-
24
-
-
0027293137
-
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts
-
Quelle, D. E., Ashmun, R. A., Shurtleff, S. A., Kato, J-Y., Bar-Sagi, D., Roussel, M. F., and Sherr, C. J. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev., 7: 1559-1571, 1993.
-
(1993)
Genes Dev.
, vol.7
, pp. 1559-1571
-
-
Quelle, D.E.1
Ashmun, R.A.2
Shurtleff, S.A.3
Kato, J.-Y.4
Bar-Sagi, D.5
Roussel, M.F.6
Sherr, C.J.7
-
25
-
-
0027938209
-
Cyclins and Cancer II: Cyclin D and cdk inhibitors come of age
-
Hunter, T., and Pines, J. Cyclins and Cancer II: cyclin D and cdk inhibitors come of age. Cell, 79: 573-582, 1994.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
26
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
Eldeiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. WAF1, a potential mediator of p53 tumor suppression. Cell, 75: 817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
Eldeiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
27
-
-
0027496935
-
The p21 CDK-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. The p21 CDK-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell, 75: 805-816, 1993.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
28
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., and Beach, D. p21 is a universal inhibitor of cyclin kinases. Nature (Lond.), 366: 701-704, 1993.
-
(1993)
Nature (Lond.)
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
29
-
-
0028176483
-
Cloning of p27(Kip1), a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
Polyak, K., Lee, M. H., Erdjument-Bromage, H., Koff, A., Roberts, J. M., Tempst, P., and Massagué, J. Cloning of p27(Kip1), a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell, 78: 59-66, 1994.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massagué, J.7
-
30
-
-
0028988159
-
p57 KIP2, a structurally distinct member of the p21 CIP1 cdk inhibitor family, is a candidate tumor suppressor gene
-
Matsuoka, S., Edwards, M. C., Bai, C., Parker, S., Zhang, P., Baldini, A., Harper, J. W., and Elledge, S. J. p57 KIP2, a structurally distinct member of the p21 CIP1 cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev., 9: 650-662, 1995.
-
(1995)
Genes Dev.
, vol.9
, pp. 650-662
-
-
Matsuoka, S.1
Edwards, M.C.2
Bai, C.3
Parker, S.4
Zhang, P.5
Baldini, A.6
Harper, J.W.7
Elledge, S.J.8
-
31
-
-
0028168242
-
p15(INK4B) is a potential effector of TGF-β-induced cell cycle arrest
-
Hannon, G. J., and Beach, D. p15(INK4B) is a potential effector of TGF-β-induced cell cycle arrest. Nature (Lond.), 371: 257-261, 1994.
-
(1994)
Nature (Lond.)
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
32
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin-D/CDK4
-
Serrano, M., Hannon, G. J., and Beach, D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin-D/CDK4. Nature (Lond.), 366: 704-707, 1993.
-
(1993)
Nature (Lond.)
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
33
-
-
0028582034
-
Growth suppression by p18, a p16INK4/ MTS1 and p14INK4B/MTS2-related cdk6 inhibitor, correlates with wild-type pRB function
-
Guan, K-L., Jenkins, C. W., Li, Y., Nichols, M. A., Wu, X., O'Keefe, C. L., Matera, A. G., and Xiong, Y. Growth suppression by p18, a p16INK4/ MTS1 and p14INK4B/MTS2-related cdk6 inhibitor, correlates with wild-type pRB function. Genes Dev., 8: 2939-2952, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 2939-2952
-
-
Guan, K.-L.1
Jenkins, C.W.2
Li, Y.3
Nichols, M.A.4
Wu, X.5
O'Keefe, C.L.6
Matera, A.G.7
Xiong, Y.8
-
34
-
-
0028911830
-
Identification of human and mouse p19, a novel cdk4 and cdk6 inhibitor with homology to p16INK4
-
Chan, F. K. M., Zhang, J., Cheng, L., Shapiro, D. N., and Winoto, A. Identification of human and mouse p19, a novel cdk4 and cdk6 inhibitor with homology to p16INK4. Mol. Cell. Biol., 15: 2682-2688, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2682-2688
-
-
Chan, F.K.M.1
Zhang, J.2
Cheng, L.3
Shapiro, D.N.4
Winoto, A.5
-
35
-
-
0028169236
-
p21-containing cyclin kinases exist in both active and inactive states
-
Zhang, H., Hannon, G. J., and Beach, D. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev., 8:1750-1758, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 1750-1758
-
-
Zhang, H.1
Hannon, G.J.2
Beach, D.3
-
36
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
Sherr, C. J. G1 phase progression: cycling on cue. Cell, 79: 551-555, 1994.
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
37
-
-
0028228907
-
Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein
-
Bates, S., Parry, D., Bonetta, L., Vousden, K., Dickson, C., and Peters, G. Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein. Oncogene, 9: 1633-1640, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 1633-1640
-
-
Bates, S.1
Parry, D.2
Bonetta, L.3
Vousden, K.4
Dickson, C.5
Peters, G.6
-
38
-
-
0028970955
-
Lack of p16INK4 or retinoblastoma protein (pRB), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines
-
He, J., Olson, J. J., and James, C. D. Lack of p16INK4 or retinoblastoma protein (pRB), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines. Cancer Res., 55: 4833-4836, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4833-4836
-
-
He, J.1
Olson, J.J.2
James, C.D.3
-
39
-
-
0028172926
-
Absence of p16(INK4) protein is restricted to the subset of lung cancer lines that retains wildtype RB
-
Otterson, G. A., Kratzke, R. A., Coxon, A., Kim, Y. W., and Kaye, F. J. Absence of p16(INK4) protein is restricted to the subset of lung cancer lines that retains wildtype RB. Oncogene, 9: 3375-3378, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 3375-3378
-
-
Otterson, G.A.1
Kratzke, R.A.2
Coxon, A.3
Kim, Y.W.4
Kaye, F.J.5
-
40
-
-
0028978274
-
A p16ink4a-insensitive cdk4 mutant targeted by cytolytic T-lymphocytes in a human melanoma
-
Washington DC
-
Wölfel, T., Hauer, M., Scheider, J., Serrano, M., Wölfel, C., Klehmann-Heib, E., DePlaen, E., Hankeln, K-H., Meier zum Büschenfelde, K-H., and Beach, D. A p16ink4a-insensitive cdk4 mutant targeted by cytolytic T-lymphocytes in a human melanoma. Science (Washington DC), 269: 1281-1284, 1995.
-
(1995)
Science
, vol.269
, pp. 1281-1284
-
-
Wölfel, T.1
Hauer, M.2
Scheider, J.3
Serrano, M.4
Wölfel, C.5
Klehmann-Heib, E.6
DePlaen, E.7
Hankeln, K.-H.8
Meier Zum Büschenfelde, K.-H.9
Beach, D.10
-
41
-
-
0027386274
-
p53, retinoblastoma, and human papillomavirus in squamous cell carcinoma and adjacent normal mucosa of the upper aerodigestive tract
-
Lee, N. K., Ye, Y. W., Chen, J., Li, X., Waber, P. G., and Nisen, P. D. p53, retinoblastoma, and human papillomavirus in squamous cell carcinoma and adjacent normal mucosa of the upper aerodigestive tract. Arch. Otolaryngol. Head Neck Surg., 119: 1125-1131, 1993.
-
(1993)
Arch. Otolaryngol. Head Neck Surg.
, vol.119
, pp. 1125-1131
-
-
Lee, N.K.1
Ye, Y.W.2
Chen, J.3
Li, X.4
Waber, P.G.5
Nisen, P.D.6
-
42
-
-
0026329868
-
Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering
-
Templeton, D. J., Park, S. H., Lanier, L., and Weinberg, R. A. Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering. Proc. Natl. Acad. Sci. USA, 88: 3033-3037, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3033-3037
-
-
Templeton, D.J.1
Park, S.H.2
Lanier, L.3
Weinberg, R.A.4
-
43
-
-
0025988149
-
Inactivation of the retinoblastoma gene on human bladder and renal cell carcinomas
-
Ishikawa, J., Xu, H-J., Hu, S-X., Yandell, D. W., Maeda, S., Kamidono, S., Benedict, W. F., and Takahashi, R. Inactivation of the retinoblastoma gene on human bladder and renal cell carcinomas. Cancer Res., 51: 5736-5743, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 5736-5743
-
-
Ishikawa, J.1
Xu, H.-J.2
Hu, S.-X.3
Yandell, D.W.4
Maeda, S.5
Kamidono, S.6
Benedict, W.F.7
Takahashi, R.8
-
44
-
-
0025009110
-
A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding
-
Kaye, F. J., Kratzke, R. A., Gerster, J. L., and Horowitz, J. M. A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding. Proc. Natl. Acad. Sci. USA, 87: 6922-6926, 1990.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6922-6926
-
-
Kaye, F.J.1
Kratzke, R.A.2
Gerster, J.L.3
Horowitz, J.M.4
-
45
-
-
0023731172
-
Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79
-
Lee, E. Y-H. P., Bookstein, R., Young, L-J., Lin, C-J., Rosenfeld, M. G., and Lee, W-H. Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79. Proc. Natl. Acad. Sci. USA, 85: 6017-6021, 1988.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6017-6021
-
-
Lee, E.Y.-H.P.1
Bookstein, R.2
Young, L.-J.3
Lin, C.-J.4
Rosenfeld, M.G.5
Lee, W.-H.6
-
46
-
-
0025953696
-
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
-
Scheffner, M., Münger, K., Byrne, J. C., and Howley, P. M. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc. Natl. Acad. Sci. USA, 88: 5523-5527, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 5523-5527
-
-
Scheffner, M.1
Münger, K.2
Byrne, J.C.3
Howley, P.M.4
-
47
-
-
0027429964
-
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-abl tyrosine kinase in the cell cycle
-
Welch, P. J., and Wang, J. Y. J. A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-abl tyrosine kinase in the cell cycle. Cell, 75: 779-790, 1993.
-
(1993)
Cell
, vol.75
, pp. 779-790
-
-
Welch, P.J.1
Wang, J.Y.J.2
-
48
-
-
0025162212
-
C-terminal truncation of the retinoblastoma gene product leads to functional inactivation
-
Shew, J-Y., Lin, B. T., Chen, P. L., Tseng, B. Y., Yang, F. T., and Lee, W-H. C-terminal truncation of the retinoblastoma gene product leads to functional inactivation. Proc. Natl. Acad. Sci. USA, 87: 6-10, 1990.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6-10
-
-
Shew, J.-Y.1
Lin, B.T.2
Chen, P.L.3
Tseng, B.Y.4
Yang, F.T.5
Lee, W.-H.6
-
49
-
-
0028200882
-
PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma
-
Phila.
-
Callender, T., El-Naggar, A. K., Lee, M. S., Frankenthaler, R., Luna, M. A., and Batsakis. J. G. PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma. Cancer (Phila.), 74: 152-158, 1994.
-
(1994)
Cancer
, vol.74
, pp. 152-158
-
-
Callender, T.1
El-Naggar, A.K.2
Lee, M.S.3
Frankenthaler, R.4
Luna, M.A.5
Batsakis, J.G.6
-
50
-
-
0028148049
-
Expression of cyclin D1 in squamous cell carcinomas of the head and neck
-
Lucas, J. M., Mountain, R. E., Gramza, A. W., Schuller, D. E., Wilkie, N. M., and Lang, J. C. Expression of cyclin D1 in squamous cell carcinomas of the head and neck. Int. J. Oncol., 5: 469-472, 1994.
-
(1994)
Int. J. Oncol.
, vol.5
, pp. 469-472
-
-
Lucas, J.M.1
Mountain, R.E.2
Gramza, A.W.3
Schuller, D.E.4
Wilkie, N.M.5
Lang, J.C.6
-
51
-
-
0029119852
-
Cloning and characterization of murine p16 INK4a and p15 INK4b genes
-
Quelle, D. E., Ashmun, R. A., Hannon, G. J., Rehberger, P. A., Trono, D., Richter, K. H., Walker, C., Beach, D., Sherr, C. J., and Serrano, M. Cloning and characterization of murine p16 INK4a and p15 INK4b genes. Oncogene, 11: 635-645, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 635-645
-
-
Quelle, D.E.1
Ashmun, R.A.2
Hannon, G.J.3
Rehberger, P.A.4
Trono, D.5
Richter, K.H.6
Walker, C.7
Beach, D.8
Sherr, C.J.9
Serrano, M.10
-
52
-
-
0029795614
-
A p18 mutant defective in cdk6 binding in human breast cancer cells
-
Lapointe, J., Lachance, Y., Labrie, Y., and Labrie, C. A p18 mutant defective in cdk6 binding in human breast cancer cells. Cancer Res., 56: 4586-4589, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4586-4589
-
-
Lapointe, J.1
Lachance, Y.2
Labrie, Y.3
Labrie, C.4
-
53
-
-
0030053513
-
Mutational analysis of the p16 family cyclin-dependent kinase inhibitors p15INK4b and p18INK4c in tumor-derived cell lines and primary tumors
-
Zariwala, M., Liu, E., and Xiong, Y. Mutational analysis of the p16 family cyclin-dependent kinase inhibitors p15INK4b and p18INK4c in tumor-derived cell lines and primary tumors. Oncogene, 12: 451-455, 1996.
-
(1996)
Oncogene
, vol.12
, pp. 451-455
-
-
Zariwala, M.1
Liu, E.2
Xiong, Y.3
-
54
-
-
0028138707
-
Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck
-
Zhang, S. Y., Kleinszanto, A. J. P., Sauter, E. R., Shafarenko, M., Mitsunaga, S., Nobori, T., Carson, D. A., Ridge, J. A., and Goodrow, T. L. Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck. Cancer Res., 54: 5050-5053, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5050-5053
-
-
Zhang, S.Y.1
Kleinszanto, A.J.P.2
Sauter, E.R.3
Shafarenko, M.4
Mitsunaga, S.5
Nobori, T.6
Carson, D.A.7
Ridge, J.A.8
Goodrow, T.L.9
-
55
-
-
0028577807
-
The D-type cyclins and their role in tumorigenesis
-
Peters, G. The D-type cyclins and their role in tumorigenesis. Cell, 18: 89-96, 1994.
-
(1994)
Cell
, vol.18
, pp. 89-96
-
-
Peters, G.1
-
56
-
-
0028275733
-
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
-
Nobori, T., Miura, K., Wu, D. J., Lois, A., Takabayashi, K., and Carson, D. A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 368: 753-756, 1994.
-
(1994)
Nature (Lond.)
, vol.368
, pp. 753-756
-
-
Nobori, T.1
Miura, K.2
Wu, D.J.3
Lois, A.4
Takabayashi, K.5
Carson, D.A.6
-
57
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Washington DC
-
Kamb, A., Gruis, N. A., Weaverfeldhaus, J., Liu, Q. Y., Harshman, K., Tavtigian, S. V., Stockert, E., Day, R. S., Johnson, B. E., and Skolnick, M. H. A cell cycle regulator potentially involved in genesis of many tumor types. Science (Washington DC), 264: 436-440, 1994.
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaverfeldhaus, J.3
Liu, Q.Y.4
Harshman, K.5
Tavtigian, S.V.6
Stockert, E.7
Day, R.S.8
Johnson, B.E.9
Skolnick, M.H.10
-
58
-
-
0028338514
-
Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma
-
Mori, T., Miura, K., Aoki, T., Nishihira, T., Shozo, N., and Nakamura, Y. Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma. Cancer Res., 54: 3396-3397, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3396-3397
-
-
Mori, T.1
Miura, K.2
Aoki, T.3
Nishihira, T.4
Shozo, N.5
Nakamura, Y.6
-
59
-
-
0028875205
-
Methylation of the 5′CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
-
Gonzalez-Zulueta, M., Bender, C. M., Yang, A. S., Nguyen, T., Beart, R. W., Van Tornout, J. M., and Jones, P. A. Methylation of the 5′CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res., 55: 4531-4535, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4531-4535
-
-
Gonzalez-Zulueta, M.1
Bender, C.M.2
Yang, A.S.3
Nguyen, T.4
Beart, R.W.5
Van Tornout, J.M.6
Jones, P.A.7
-
60
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman, J. G., Merlo, A., Mao, L., Lapidus, R. G., Issa, J. P., Davidson, N. E., Sidransky, D., and Baylin, S. B. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res., 55: 4525-4530, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
61
-
-
0029011539
-
5′CpG island methylation is associated with transcriptional silencing of the tumor suppressor CDKN2/p16 in human cancers
-
Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Gabrielson, E., Burger, P. C., Baylin, S. B., and Sidransky, D. 5′CpG island methylation is associated with transcriptional silencing of the tumor suppressor CDKN2/p16 in human cancers. Nat. Med., 7: 686-692, 1995.
-
(1995)
Nat. Med.
, vol.7
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
62
-
-
9444255067
-
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma
-
Reed, A. L., Califano, J., Cairns, P., Westra, W. H., Jones, R. M., Koch, W., Ahrend, S., Eby, Y., Sewell, D., Nawroz, H., Bartek, J., and Sidransky, D. High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma. Cancer Res., 56: 3630-3633, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 3630-3633
-
-
Reed, A.L.1
Califano, J.2
Cairns, P.3
Westra, W.H.4
Jones, R.M.5
Koch, W.6
Ahrend, S.7
Eby, Y.8
Sewell, D.9
Nawroz, H.10
Bartek, J.11
Sidransky, D.12
-
63
-
-
0028986612
-
Loss of p16INK4 expression is frequent in high grade gliomas
-
Nishikawa, R., Furnari, F. B., Lin, H., Arap, W., Berger, M. S., Cavenee, W. K., and Su Hang, H-J. Loss of p16INK4 expression is frequent in high grade gliomas. Cancer Res., 55: 1941-1945, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1941-1945
-
-
Nishikawa, R.1
Furnari, F.B.2
Lin, H.3
Arap, W.4
Berger, M.S.5
Cavenee, W.K.6
Su Hang, H.-J.7
-
64
-
-
0028652269
-
CDKN2 (p16/MTS1) gene deletions or cdk4 amplification occurs in the majority of glioblastomas
-
Schmidt, E. E., Ichimura, K., Reifenberger, G., and Collins, V. P. CDKN2 (p16/MTS1) gene deletions or cdk4 amplification occurs in the majority of glioblastomas. Cancer Res., 54: 6321-6324, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 6321-6324
-
-
Schmidt, E.E.1
Ichimura, K.2
Reifenberger, G.3
Collins, V.P.4
-
65
-
-
0028879890
-
Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the cdk4 gene in glioma
-
Sonoda, Y., Yoshimoto, T., and Sekiya, T. Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the cdk4 gene in glioma. Oncogene, 11: 2145-2149, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 2145-2149
-
-
Sonoda, Y.1
Yoshimoto, T.2
Sekiya, T.3
-
66
-
-
0029666504
-
Association of CDKN2/ p16ink4A with human head and neck keratinocyte replicative senescence: Relationship of dysfunction to immortality and neoplasia
-
Loughran, O., Malliri, A., Owens, D., Gallimore, P. H., Stanley, M. A., Ozanne, B., Frame, M. C., and Parkinson, E. K. Association of CDKN2/ p16ink4A with human head and neck keratinocyte replicative senescence: relationship of dysfunction to immortality and neoplasia. Oncogene, 13: 561-568, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 561-568
-
-
Loughran, O.1
Malliri, A.2
Owens, D.3
Gallimore, P.H.4
Stanley, M.A.5
Ozanne, B.6
Frame, M.C.7
Parkinson, E.K.8
-
67
-
-
0019124443
-
Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes
-
Rheinwald, J. G., and Beckett, M. A. Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell, 22: 629-632, 1980.
-
(1980)
Cell
, vol.22
, pp. 629-632
-
-
Rheinwald, J.G.1
Beckett, M.A.2
-
68
-
-
0019471387
-
Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas
-
Rheinwald, J. G., and Beckett, M. A. Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas. Cancer Res., 41: 1657-1663, 1981.
-
(1981)
Cancer Res.
, vol.41
, pp. 1657-1663
-
-
Rheinwald, J.G.1
Beckett, M.A.2
-
69
-
-
0024095251
-
Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma
-
Schlegel, R., Phelps, W. C., Zhang, Y-L., and Barbosa, M. Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma. EMBO J., 7: 3181-3187, 1988.
-
(1988)
EMBO J.
, vol.7
, pp. 3181-3187
-
-
Schlegel, R.1
Phelps, W.C.2
Zhang, Y.-L.3
Barbosa, M.4
-
70
-
-
0029941446
-
Inhibition of p53-mediated growth arrest by overexpression of cyclin-dependent kinases
-
Latham, K. M., Eastman, S. W., Wong, A., and Hinds, P. W. Inhibition of p53-mediated growth arrest by overexpression of cyclin-dependent kinases. Mol. Cell. Biol., 16: 4445-4455, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4445-4455
-
-
Latham, K.M.1
Eastman, S.W.2
Wong, A.3
Hinds, P.W.4
-
71
-
-
0026802989
-
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
-
Hinds, P. W., Mittnacht, S., Dulic, V., Arnold, A., Reed, S. I., and Weinberg, R. A. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell, 70: 993-1006, 1992.
-
(1992)
Cell
, vol.70
, pp. 993-1006
-
-
Hinds, P.W.1
Mittnacht, S.2
Dulic, V.3
Arnold, A.4
Reed, S.I.5
Weinberg, R.A.6
-
72
-
-
0004265596
-
-
New York: Greene Publishing Associates and John Wiley & Sons
-
Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. Short Protocols in Molecular Biology, Ed. 2, pp. 2-4. New York: Greene Publishing Associates and John Wiley & Sons, 1992.
-
(1992)
Short Protocols in Molecular Biology, Ed. 2
, pp. 2-4
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
73
-
-
0023731010
-
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
-
DeCaprio, J. A., Ludlow, J. W., Figge, J., Shew, J-Y., Huang, C-M., Lee, W-H., Marsilio, E., Paucho, E., and Livingston, D. M. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell, 54: 275-283, 1988.
-
(1988)
Cell
, vol.54
, pp. 275-283
-
-
DeCaprio, J.A.1
Ludlow, J.W.2
Figge, J.3
Shew, J.-Y.4
Huang, C.-M.5
Lee, W.-H.6
Marsilio, E.7
Paucho, E.8
Livingston, D.M.9
-
74
-
-
0027411079
-
The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein
-
Wu, E. W., Clemens, K. E., Heck, D. V., and Münger, K. The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein. J. Virol., 67: 2402-2407, 1993.
-
(1993)
J. Virol.
, vol.67
, pp. 2402-2407
-
-
Wu, E.W.1
Clemens, K.E.2
Heck, D.V.3
Münger, K.4
-
75
-
-
0029560071
-
Deletion and transfection analysis of the p15/MTS2 gene in malignant melanomas
-
Tenan, M., Benedetti, S., and Finocchiaro, G. Deletion and transfection analysis of the p15/MTS2 gene in malignant melanomas. Biochem. Biophys. Res. Commun., 217: 195-202, 1995.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.217
, pp. 195-202
-
-
Tenan, M.1
Benedetti, S.2
Finocchiaro, G.3
-
76
-
-
0029129298
-
Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines
-
Zhou, X., Suzuki, H., Shimada, Y., Imamura, M., Yin, J., Jiang, H., Tarmin, L., Abraham, J. M., and Meltzer, S. J. Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines. Genes Chromosomes Cancer, 13: 285-290, 1995.
-
(1995)
Genes Chromosomes Cancer
, vol.13
, pp. 285-290
-
-
Zhou, X.1
Suzuki, H.2
Shimada, Y.3
Imamura, M.4
Yin, J.5
Jiang, H.6
Tarmin, L.7
Abraham, J.M.8
Meltzer, S.J.9
-
77
-
-
0028085975
-
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
-
Kamb, A., Shattuck-Eidens, D., Eeles, R., Liu, Q., Gruis, N. A., Ding, W., Hussey, C., Tran, T., Miki, Y., Weaver-Feldhaus, J., McClure, M., Aitken, J. F., Anderson, D. E., Bergman, W., Frants, R., Goldgar, D. E., Green, A., MacLennan, R., Martin, N. G., Meyer, L. J., Youl, P., Zone, J. J., Skolnick, M. H., and Cannon-Albright, L. A. Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nat. Genet., 8: 22-26, 1994.
-
(1994)
Nat. Genet.
, vol.8
, pp. 22-26
-
-
Kamb, A.1
Shattuck-Eidens, D.2
Eeles, R.3
Liu, Q.4
Gruis, N.A.5
Ding, W.6
Hussey, C.7
Tran, T.8
Miki, Y.9
Weaver-Feldhaus, J.10
McClure, M.11
Aitken, J.F.12
Anderson, D.E.13
Bergman, W.14
Frants, R.15
Goldgar, D.E.16
Green, A.17
MacLennan, R.18
Martin, N.G.19
Meyer, L.J.20
Youl, P.21
Zone, J.J.22
Skolnick, M.H.23
Cannon-Albright, L.A.24
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