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Volumn 173, Issue 2, 2008, Pages 526-535

CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1;

EID: 48749133336     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2008.071124     Document Type: Article
Times cited : (12)

References (51)
  • 2
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA: The retinoblastoma protein and cell cycle control. Cell 1995, 81:323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 3
    • 0030845187 scopus 로고    scopus 로고
    • Differential interaction of the cyclin-dependent kinase (cdk) inhibitor p27Kip1 with cyclin A-cdk2 and cyclin D2-cdk4
    • Blain S, Montalvo E, Massague J: Differential interaction of the cyclin-dependent kinase (cdk) inhibitor p27Kip1 with cyclin A-cdk2 and cyclin D2-cdk4. J Biol Chem 1997, 272:25863-25872
    • (1997) J Biol Chem , vol.272 , pp. 25863-25872
    • Blain, S.1    Montalvo, E.2    Massague, J.3
  • 6
    • 0033214995 scopus 로고    scopus 로고
    • Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1)
    • Perez-Roger I, Kim SH, Griffiths B, Sewing A, Land H: Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). EMBO J 1999, 18:5310-5320
    • (1999) EMBO J , vol.18 , pp. 5310-5320
    • Perez-Roger, I.1    Kim, S.H.2    Griffiths, B.3    Sewing, A.4    Land, H.5
  • 8
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • van den Heuvel S, Harlow E: Distinct roles for cyclin-dependent kinases in cell cycle control. Science 1993, 262:2050-2054
    • (1993) Science , vol.262 , pp. 2050-2054
    • van den Heuvel, S.1    Harlow, E.2
  • 9
    • 0028909645 scopus 로고
    • Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
    • Ohtsubo M, Theodoras A, Schumacher J, Roberts J, Pagano M: Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol 1995, 15:1559-1571
    • (1995) Mol Cell Biol , vol.15 , pp. 1559-1571
    • Ohtsubo, M.1    Theodoras, A.2    Schumacher, J.3    Roberts, J.4    Pagano, M.5
  • 10
    • 0026583746 scopus 로고
    • Cyclin A is required at two points in the human cell cycle
    • Pagano M, Pepperkok R, Verde F, Ansorge W, Draetta G: Cyclin A is required at two points in the human cell cycle. EMBO J 1992, 11:961-971
    • (1992) EMBO J , vol.11 , pp. 961-971
    • Pagano, M.1    Pepperkok, R.2    Verde, F.3    Ansorge, W.4    Draetta, G.5
  • 11
    • 0027298902 scopus 로고
    • The cdk2 kinase is required for the G1-to-S transition in mammalian cells
    • Tsai LH, Lees E, Faha B, Harlow E, Riabowol K: The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene 1993, 8:1593-1602
    • (1993) Oncogene , vol.8 , pp. 1593-1602
    • Tsai, L.H.1    Lees, E.2    Faha, B.3    Harlow, E.4    Riabowol, K.5
  • 14
    • 20444410393 scopus 로고    scopus 로고
    • Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1)
    • Martín A, Odajima J, Hunt SL, Dubus P, Ortega S, Malumbres M, Barbacid M: Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1). Cancer Cell 2005, 7:591-598
    • (2005) Cancer Cell , vol.7 , pp. 591-598
    • Martín, A.1    Odajima, J.2    Hunt, S.L.3    Dubus, P.4    Ortega, S.5    Malumbres, M.6    Barbacid, M.7
  • 17
    • 0036225006 scopus 로고    scopus 로고
    • Expression of cell cycle control proteins in normal epithelium, premalignant and malignant lesions of oral cavity
    • Shintani S, Mihara M, Nakahara Y, Kiyota A, Ueyama Y, Matsumura T, Wong DT: Expression of cell cycle control proteins in normal epithelium, premalignant and malignant lesions of oral cavity. Oral Oncol 2002, 38:235-243
    • (2002) Oral Oncol , vol.38 , pp. 235-243
    • Shintani, S.1    Mihara, M.2    Nakahara, Y.3    Kiyota, A.4    Ueyama, Y.5    Matsumura, T.6    Wong, D.T.7
  • 19
    • 0031307157 scopus 로고    scopus 로고
    • The role of cyclin E in cell proliferation, development and cancer
    • Keyomarsi K, Herliczek T: The role of cyclin E in cell proliferation, development and cancer. Prog Cell Cycle Res 1997, 3:171-191
    • (1997) Prog Cell Cycle Res , vol.3 , pp. 171-191
    • Keyomarsi, K.1    Herliczek, T.2
  • 22
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama K, Ishida N, Shirane M, Inomata A, Inoue T, Shishido N, Horii I, Loh DY: Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996, 85:707-720
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Horii, I.7    Loh, D.Y.8
  • 25
    • 0034650404 scopus 로고    scopus 로고
    • Processing of cyclin E differs between normal and tumor breast cells
    • Harwell RM, Porter DC, Danes C, Keyomarsi K: Processing of cyclin E differs between normal and tumor breast cells. Cancer Res 2000, 60:481-489
    • (2000) Cancer Res , vol.60 , pp. 481-489
    • Harwell, R.M.1    Porter, D.C.2    Danes, C.3    Keyomarsi, K.4
  • 27
    • 34248195589 scopus 로고    scopus 로고
    • Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression
    • Corsino P, Davis B, Law M, Chytil A, Forrester E, Norgaard P, Teoh N, Law B: Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression. Cancer Res 2007, 67:3135-3144
    • (2007) Cancer Res , vol.67 , pp. 3135-3144
    • Corsino, P.1    Davis, B.2    Law, M.3    Chytil, A.4    Forrester, E.5    Norgaard, P.6    Teoh, N.7    Law, B.8
  • 28
    • 0028243879 scopus 로고    scopus 로고
    • Wang TC, Cardiff RD, Zukerberg L, Lees E, Arnold A, Schmidt EV: Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 1994, 369:669-671
    • Wang TC, Cardiff RD, Zukerberg L, Lees E, Arnold A, Schmidt EV: Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 1994, 369:669-671
  • 31
    • 35448958408 scopus 로고    scopus 로고
    • Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis
    • Macias E, Kim Y, Miliani de Marval PL, Klein-Szanto A, Rodriguez-Puebla ML: Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis. Cancer Res 2007, 67:9713-9720
    • (2007) Cancer Res , vol.67 , pp. 9713-9720
    • Macias, E.1    Kim, Y.2    Miliani de Marval, P.L.3    Klein-Szanto, A.4    Rodriguez-Puebla, M.L.5
  • 33
    • 0027973880 scopus 로고
    • Sequences 5′ of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development
    • Ramírez A, Bravo A, Jorcano J, Vidal M: Sequences 5′ of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development. Differentiation 1994, 58:53-64
    • (1994) Differentiation , vol.58 , pp. 53-64
    • Ramírez, A.1    Bravo, A.2    Jorcano, J.3    Vidal, M.4
  • 34
    • 0037195268 scopus 로고    scopus 로고
    • p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation
    • Minella AC, Swanger J, Bryant E, Welcker M, Hwang H, Clurman BE: p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation. Curr Biol 2002, 12:1817-1827
    • (2002) Curr Biol , vol.12 , pp. 1817-1827
    • Minella, A.C.1    Swanger, J.2    Bryant, E.3    Welcker, M.4    Hwang, H.5    Clurman, B.E.6
  • 37
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
    • Quintanilla M, Brown K, Ramsden M, Balmain A: Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 1986, 322:78-80
    • (1986) Nature , vol.322 , pp. 78-80
    • Quintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 38
    • 0033590604 scopus 로고    scopus 로고
    • Co-amplification and overexpression of CDK4. SAS and MDM2 occurs frequently in human parosteal osteosarcomas
    • Wunder JS, Eppert K, Burrow SR, Gokgoz N, Bell RS, Andrulis IL: Co-amplification and overexpression of CDK4. SAS and MDM2 occurs frequently in human parosteal osteosarcomas. Oncogene 1999, 18:783-788
    • (1999) Oncogene , vol.18 , pp. 783-788
    • Wunder, J.S.1    Eppert, K.2    Burrow, S.R.3    Gokgoz, N.4    Bell, R.S.5    Andrulis, I.L.6
  • 39
    • 0033579870 scopus 로고    scopus 로고
    • CDK4 gene amplification in osteosarcoma: Reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons
    • Wei G, Lonardo F, Ueda T, Kim T, Huvos AG, Healey JH, Ladanyi M: CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons. Int J Cancer 1999, 80:199-204
    • (1999) Int J Cancer , vol.80 , pp. 199-204
    • Wei, G.1    Lonardo, F.2    Ueda, T.3    Kim, T.4    Huvos, A.G.5    Healey, J.H.6    Ladanyi, M.7
  • 40
    • 0036981749 scopus 로고    scopus 로고
    • MDM2 and CDK4 expression in carcinosarcoma of the esophagus: Comparison with squamous cell carcinoma
    • Nikitakis N, Drachenberg C, Papadimitriou J: MDM2 and CDK4 expression in carcinosarcoma of the esophagus: comparison with squamous cell carcinoma. Exp Mol Pathol 2002, 73:198-208
    • (2002) Exp Mol Pathol , vol.73 , pp. 198-208
    • Nikitakis, N.1    Drachenberg, C.2    Papadimitriou, J.3
  • 41
    • 0027454445 scopus 로고
    • Coamplification of the Cdk4 gene with MDM2 and GL1 in human sarcomas
    • Khatib Z, Matsushime H, Valentine M: Coamplification of the Cdk4 gene with MDM2 and GL1 in human sarcomas. Cancer Res 1993, 53:5535-5541
    • (1993) Cancer Res , vol.53 , pp. 5535-5541
    • Khatib, Z.1    Matsushime, H.2    Valentine, M.3
  • 43
    • 0029664339 scopus 로고    scopus 로고
    • Germline mutation in the p16Ink4a binding domain of cdk4 in familial melanoma
    • Zuo L: Germline mutation in the p16Ink4a binding domain of cdk4 in familial melanoma. Nat Genet 1996, 12:97-99
    • (1996) Nat Genet , vol.12 , pp. 97-99
    • Zuo, L.1
  • 44
    • 1842477408 scopus 로고    scopus 로고
    • Activation of cyclin-dependent kinase 2 by full length and low molecular weight forms of cyclin E in breast cancer cells
    • Harwell RM, Mull BB, Porter DC, Keyomarsi K: Activation of cyclin-dependent kinase 2 by full length and low molecular weight forms of cyclin E in breast cancer cells. J Biol Chem 2004, 279:12695-12705
    • (2004) J Biol Chem , vol.279 , pp. 12695-12705
    • Harwell, R.M.1    Mull, B.B.2    Porter, D.C.3    Keyomarsi, K.4
  • 45
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM: CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999, 13:1501-12
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 46
    • 0032981481 scopus 로고    scopus 로고
    • Induced expression of p16Ink4a inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes
    • McConnell B, Gregory F, Stott F, Hara E, Peters G: Induced expression of p16Ink4a inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes. Mol Cell Biol 1999, 19:1981-1989
    • (1999) Mol Cell Biol , vol.19 , pp. 1981-1989
    • McConnell, B.1    Gregory, F.2    Stott, F.3    Hara, E.4    Peters, G.5
  • 47
    • 0041327168 scopus 로고    scopus 로고
    • Proliferation of cancer cells despite CDK2 inhibition
    • Tetsu O, McCormick F: Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell 2003, 3:233-245
    • (2003) Cancer Cell , vol.3 , pp. 233-245
    • Tetsu, O.1    McCormick, F.2
  • 49
    • 0022537060 scopus 로고
    • Evidence that a slowly cycling subpopulation of adult murine epidermal cells retains carcinogen
    • Morris RJ, Fischer SM, Slaga TJ: Evidence that a slowly cycling subpopulation of adult murine epidermal cells retains carcinogen. Cancer Res 1986, 46:3061-3066
    • (1986) Cancer Res , vol.46 , pp. 3061-3066
    • Morris, R.J.1    Fischer, S.M.2    Slaga, T.J.3
  • 51
    • 34547928992 scopus 로고    scopus 로고
    • p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability
    • Minella AC, Grim JE, Welcker M, Clurman BE: p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability. Oncogene 2007, 26:6948-6953
    • (2007) Oncogene , vol.26 , pp. 6948-6953
    • Minella, A.C.1    Grim, J.E.2    Welcker, M.3    Clurman, B.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.