Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 283, Issue 3 27-3, 2002, Pages

  Le Cras, Timothy D ^a   Markham, Neil E ^a   Tuder, Rubin M ^b   Voelkel, Norbert F ^c   Abman, Steven H ^a  

^a Children's Hospital Colorado   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Alveogenesis; Angiogenesis; Bronchopulmonary dysplasia; Postnatal lung development; Pulmonary vascular development; Vascular endothelial growth factor

Indexed keywords

PROTEIN TYROSINE KINASE INHIBITOR; SEMAXANIB; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR INHIBITOR;

ANGIOGENESIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; EMPHYSEMA; HEART RIGHT VENTRICLE HYPERTROPHY; HEMATOCRIT; LUNG ALVEOLUS EPITHELIUM; LUNG BLOOD VESSEL; LUNG DEVELOPMENT; LUNG DYSPLASIA; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

EID: 0036723641     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00408.2001     Document Type: Article

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