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Volumn 89, Issue 2, 2011, Pages 136-148

Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity

Author keywords

Antiviral therapy; Chronic liver disease; HCV; Hepatitis C virus; Tartrolon; Viral life cycle

Indexed keywords

LUCIFERASE; SMALL MOLECULE TRANSPORT AGENT;

EID: 78751634447     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2010.12.005     Document Type: Article
Times cited : (39)

References (97)
  • 1
    • 54549100206 scopus 로고    scopus 로고
    • Epothilones in breast cancer: current status and future directions
    • Atzori F., Fornier M. Epothilones in breast cancer: current status and future directions. Expert Rev. Anticancer Ther. 2008, 8:1299-1311.
    • (2008) Expert Rev. Anticancer Ther. , vol.8 , pp. 1299-1311
    • Atzori, F.1    Fornier, M.2
  • 3
    • 0037416146 scopus 로고    scopus 로고
    • Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
    • Bartosch B., Dubuisson J., Cosset F.L. Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes. J. Exp. Med. 2003, 197:633-642.
    • (2003) J. Exp. Med. , vol.197 , pp. 633-642
    • Bartosch, B.1    Dubuisson, J.2    Cosset, F.L.3
  • 4
    • 20744437263 scopus 로고    scopus 로고
    • An interplay between hypervariable region 1 of the hepatitis C virus E2 glycoprotein, the scavenger receptor BI, and high-density lipoprotein promotes both enhancement of infection and protection against neutralizing antibodies
    • Bartosch B., Verney G., Dreux M., Donot P., Morice Y., Penin F., Pawlotsky J.M., Lavillette D., Cosset F.L. An interplay between hypervariable region 1 of the hepatitis C virus E2 glycoprotein, the scavenger receptor BI, and high-density lipoprotein promotes both enhancement of infection and protection against neutralizing antibodies. J. Virol. 2005, 79:8217-8229.
    • (2005) J. Virol. , vol.79 , pp. 8217-8229
    • Bartosch, B.1    Verney, G.2    Dreux, M.3    Donot, P.4    Morice, Y.5    Penin, F.6    Pawlotsky, J.M.7    Lavillette, D.8    Cosset, F.L.9
  • 5
  • 8
    • 0036893332 scopus 로고    scopus 로고
    • Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication
    • Blight K.J., McKeating J.A., Rice C.M. Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J. Virol. 2002, 76:13001-13014.
    • (2002) J. Virol. , vol.76 , pp. 13001-13014
    • Blight, K.J.1    McKeating, J.A.2    Rice, C.M.3
  • 9
    • 47649114826 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces lipid droplet redistribution in a microtubule- and dynein-dependent manner
    • Boulant S., Douglas M.W., Moody L., Budkowska A., Targett-Adams P., McLauchlan J. Hepatitis C virus core protein induces lipid droplet redistribution in a microtubule- and dynein-dependent manner. Traffic 2008, 9:1268-1282.
    • (2008) Traffic , vol.9 , pp. 1268-1282
    • Boulant, S.1    Douglas, M.W.2    Moody, L.3    Budkowska, A.4    Targett-Adams, P.5    McLauchlan, J.6
  • 10
    • 23444437041 scopus 로고    scopus 로고
    • Screening for hepatitis C virus antiviral activity with a cell-based secreted alkaline phosphatase reporter replicon system
    • Bourne N., Pyles R.B., Yi M., Veselenak R.L., Davis M.M., Lemon S.M. Screening for hepatitis C virus antiviral activity with a cell-based secreted alkaline phosphatase reporter replicon system. Antiviral Res. 2005, 67:76-82.
    • (2005) Antiviral Res. , vol.67 , pp. 76-82
    • Bourne, N.1    Pyles, R.B.2    Yi, M.3    Veselenak, R.L.4    Davis, M.M.5    Lemon, S.M.6
  • 11
    • 23944480609 scopus 로고    scopus 로고
    • Hepatitis C and liver transplantation
    • Brown R.S. Hepatitis C and liver transplantation. Nature 2005, 436:973-978.
    • (2005) Nature , vol.436 , pp. 973-978
    • Brown, R.S.1
  • 12
    • 0029795285 scopus 로고    scopus 로고
    • Murine leukemia virus-based Tat-inducible long terminal repeat replacement vectors: a new system for anti-human immunodeficiency virus gene therapy
    • Cannon P.M., Kim N., Kingsman S.M., Kingsman A.J. Murine leukemia virus-based Tat-inducible long terminal repeat replacement vectors: a new system for anti-human immunodeficiency virus gene therapy. J. Virol. 1996, 70:8234-8240.
    • (1996) J. Virol. , vol.70 , pp. 8234-8240
    • Cannon, P.M.1    Kim, N.2    Kingsman, S.M.3    Kingsman, A.J.4
  • 14
    • 37049007864 scopus 로고    scopus 로고
    • Human apolipoprotein e is required for infectivity and production of hepatitis C virus in cell culture
    • Chang K.S., Jiang J., Cai Z., Luo G. Human apolipoprotein e is required for infectivity and production of hepatitis C virus in cell culture. J. Virol. 2007, 81:13783-13793.
    • (2007) J. Virol. , vol.81 , pp. 13783-13793
    • Chang, K.S.1    Jiang, J.2    Cai, Z.3    Luo, G.4
  • 15
    • 77649247824 scopus 로고    scopus 로고
    • A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
    • Chockalingam K., Simeon R.L., Rice C.M., Chen Z. A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:3764-3769.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 3764-3769
    • Chockalingam, K.1    Simeon, R.L.2    Rice, C.M.3    Chen, Z.4
  • 17
    • 43549109807 scopus 로고    scopus 로고
    • Medical procedures as a risk factor for HCV infection in developed countries: do we neglect a significant problem in medical care?
    • Deterding K., Wiegand J., Grüner N., Wedemeyer H. Medical procedures as a risk factor for HCV infection in developed countries: do we neglect a significant problem in medical care?. J. Hepatol. 2008, 48:1019-1020.
    • (2008) J. Hepatol. , vol.48 , pp. 1019-1020
    • Deterding, K.1    Wiegand, J.2    Grüner, N.3    Wedemeyer, H.4
  • 20
    • 1042263998 scopus 로고    scopus 로고
    • Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells
    • Elnakady Y.A., Sasse F., Lünsdorf H., Reichenbach H. Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells. Biochem. Pharmacol. 2004, 67:927-935.
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 927-935
    • Elnakady, Y.A.1    Sasse, F.2    Lünsdorf, H.3    Reichenbach, H.4
  • 22
    • 10644226734 scopus 로고    scopus 로고
    • Kissing-loop interaction in the 3' end of the hepatitis C virus genome essential for RNA replication
    • Friebe P., Boudet J., Simorre J.P., Bartenschlager R. Kissing-loop interaction in the 3' end of the hepatitis C virus genome essential for RNA replication. J. Virol. 2005, 79:380-392.
    • (2005) J. Virol. , vol.79 , pp. 380-392
    • Friebe, P.1    Boudet, J.2    Simorre, J.P.3    Bartenschlager, R.4
  • 23
    • 39749098739 scopus 로고    scopus 로고
    • Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion
    • Gastaminza P., Cheng G., Wieland S., Zhong J., Liao W., Chisari F.V. Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion. J. Virol. 2008, 82:2120-2129.
    • (2008) J. Virol. , vol.82 , pp. 2120-2129
    • Gastaminza, P.1    Cheng, G.2    Wieland, S.3    Zhong, J.4    Liao, W.5    Chisari, F.V.6
  • 24
    • 33750698300 scopus 로고    scopus 로고
    • Differential biophysical properties of infectious intracellular and secreted hepatitis C virus particles
    • Gastaminza P., Kapadia S.B., Chisari F.V. Differential biophysical properties of infectious intracellular and secreted hepatitis C virus particles. J. Virol. 2006, 80:11074-11081.
    • (2006) J. Virol. , vol.80 , pp. 11074-11081
    • Gastaminza, P.1    Kapadia, S.B.2    Chisari, F.V.3
  • 25
    • 76249126162 scopus 로고    scopus 로고
    • Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection
    • Gastaminza P., Whitten-Bauer C., Chisari F.V. Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:291-296.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 291-296
    • Gastaminza, P.1    Whitten-Bauer, C.2    Chisari, F.V.3
  • 26
    • 0345144016 scopus 로고    scopus 로고
    • Identification of the hepatitis C virus RNA replication complex in huh-7 cells harboring subgenomic replicons
    • Gosert R., Egger D., Lohmann V., Bartenschlager R., Blum H.E., Bienz K., Moradpour D. Identification of the hepatitis C virus RNA replication complex in huh-7 cells harboring subgenomic replicons. J. Virol. 2003, 77:5487-5492.
    • (2003) J. Virol. , vol.77 , pp. 5487-5492
    • Gosert, R.1    Egger, D.2    Lohmann, V.3    Bartenschlager, R.4    Blum, H.E.5    Bienz, K.6    Moradpour, D.7
  • 27
    • 61949320778 scopus 로고    scopus 로고
    • Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs
    • Gottwein J.M., Scheel T.K., Jensen T.B., Lademann J.B., Prentoe J.C., Knudsen M.L., Hoegh A.M., Bukh J. Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs. Hepatology 2009, 49:364-377.
    • (2009) Hepatology , vol.49 , pp. 364-377
    • Gottwein, J.M.1    Scheel, T.K.2    Jensen, T.B.3    Lademann, J.B.4    Prentoe, J.C.5    Knudsen, M.L.6    Hoegh, A.M.7    Bukh, J.8
  • 30
    • 73849132880 scopus 로고    scopus 로고
    • Mouse-specific residues of claudin-1 limit hepatitis C virus genotype 2a infection in a human hepatocyte cell line
    • Haid S., Windisch M.P., Bartenschlager R., Pietschmann T. Mouse-specific residues of claudin-1 limit hepatitis C virus genotype 2a infection in a human hepatocyte cell line. J. Virol. 2010, 84:964-975.
    • (2010) J. Virol. , vol.84 , pp. 964-975
    • Haid, S.1    Windisch, M.P.2    Bartenschlager, R.3    Pietschmann, T.4
  • 31
    • 0027163740 scopus 로고
    • Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
    • Hijikata M., Mizushima H., Akagi T., Mori S., Kakiuchi N., Kato N., Tanaka T., Kimura K., Shimotohno K. Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J. Virol. 1993, 67:4665-4675.
    • (1993) J. Virol. , vol.67 , pp. 4665-4675
    • Hijikata, M.1    Mizushima, H.2    Akagi, T.3    Mori, S.4    Kakiuchi, N.5    Kato, N.6    Tanaka, T.7    Kimura, K.8    Shimotohno, K.9
  • 32
    • 0036828783 scopus 로고    scopus 로고
    • Course and outcome of hepatitis C
    • Hoofnagle J.H. Course and outcome of hepatitis C. Hepatology 2002, 36:S21-S29.
    • (2002) Hepatology , vol.36
    • Hoofnagle, J.H.1
  • 33
    • 65349119424 scopus 로고    scopus 로고
    • Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
    • Hopkins C.D., Wipf P. Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides. Nat. Prod. Rep. 2009, 26:585-601.
    • (2009) Nat. Prod. Rep. , vol.26 , pp. 585-601
    • Hopkins, C.D.1    Wipf, P.2
  • 35
    • 34250337631 scopus 로고    scopus 로고
    • Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
    • Huang H., Sun F., Owen D.M., Li W., Chen Y., Gale M., Ye J. Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:5848-5853.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 5848-5853
    • Huang, H.1    Sun, F.2    Owen, D.M.3    Li, W.4    Chen, Y.5    Gale, M.6    Ye, J.7
  • 37
    • 0028837282 scopus 로고
    • The tartrolons, new boron-containing antibiotics from a myxobacterium, Sorangium cellulosum
    • Irschik H., Schummer D., Gerth K., Höfle G., Reichenbach H. The tartrolons, new boron-containing antibiotics from a myxobacterium, Sorangium cellulosum. J. Antibiot. (Tokyo) 1995, 48:26-30.
    • (1995) J. Antibiot. (Tokyo) , vol.48 , pp. 26-30
    • Irschik, H.1    Schummer, D.2    Gerth, K.3    Höfle, G.4    Reichenbach, H.5
  • 38
    • 34447344496 scopus 로고    scopus 로고
    • Etnangien, a macrolide-polyene antibiotic from Sorangium cellulosum that inhibits nucleic acid polymerases
    • Irschik H., Schummer D., Höfle G., Reichenbach H., Steinmetz H., Jansen R. Etnangien, a macrolide-polyene antibiotic from Sorangium cellulosum that inhibits nucleic acid polymerases. J. Nat. Prod. 2007, 70:1060-1063.
    • (2007) J. Nat. Prod. , vol.70 , pp. 1060-1063
    • Irschik, H.1    Schummer, D.2    Höfle, G.3    Reichenbach, H.4    Steinmetz, H.5    Jansen, R.6
  • 39
    • 34547734952 scopus 로고    scopus 로고
    • Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus
    • Jones C.T., Murray C.L., Eastman D.K., Tassello J., Rice C.M. Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus. J. Virol. 2007, 81:8374-8383.
    • (2007) J. Virol. , vol.81 , pp. 8374-8383
    • Jones, C.T.1    Murray, C.L.2    Eastman, D.K.3    Tassello, J.4    Rice, C.M.5
  • 40
    • 0035947456 scopus 로고    scopus 로고
    • Use of VSV-G pseudotyped retroviral vectors to target murine osteoprogenitor cells
    • Kalajzic I., Stover M.L., Liu P., Kalajzic Z., Rowe D.W., Lichtler A.C. Use of VSV-G pseudotyped retroviral vectors to target murine osteoprogenitor cells. Virology 2001, 284:37-45.
    • (2001) Virology , vol.284 , pp. 37-45
    • Kalajzic, I.1    Stover, M.L.2    Liu, P.3    Kalajzic, Z.4    Rowe, D.W.5    Lichtler, A.C.6
  • 41
    • 14044265120 scopus 로고    scopus 로고
    • Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids
    • Kapadia S.B., Chisari F.V. Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:2561-2566.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 2561-2566
    • Kapadia, S.B.1    Chisari, F.V.2
  • 45
    • 50149114689 scopus 로고    scopus 로고
    • Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A
    • Lai C.K., Jeng K.S., Machida K., Lai M.M. Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A. J. Virol. 2008, 82:8838-8848.
    • (2008) J. Virol. , vol.82 , pp. 8838-8848
    • Lai, C.K.1    Jeng, K.S.2    Machida, K.3    Lai, M.M.4
  • 46
    • 34547094367 scopus 로고    scopus 로고
    • Hepatitis C Virus
    • Lipincott Williams & Wilkins, Philadelphia, D.M. Knipe, P.M. Howley (Eds.)
    • Lemon S.M., Walker C.M., Alter M.J., Yi M. Hepatitis C Virus. Fields Virology 2007, 1253-1304. Lipincott Williams & Wilkins, Philadelphia. 5 edn. D.M. Knipe, P.M. Howley (Eds.).
    • (2007) Fields Virology , pp. 1253-1304
    • Lemon, S.M.1    Walker, C.M.2    Alter, M.J.3    Yi, M.4
  • 49
    • 59649117842 scopus 로고    scopus 로고
    • Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection
    • Liu S., Yang W., Shen L., Turner J.R., Coyne C.B., Wang T. Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection. J. Virol. 2009, 83:2011-2014.
    • (2009) J. Virol. , vol.83 , pp. 2011-2014
    • Liu, S.1    Yang, W.2    Shen, L.3    Turner, J.R.4    Coyne, C.B.5    Wang, T.6
  • 52
    • 33747797031 scopus 로고    scopus 로고
    • Treating viral hepatitis C: efficacy, side effects, and complications
    • Manns M.P., Wedemeyer H., Cornberg M. Treating viral hepatitis C: efficacy, side effects, and complications. Gut 2006, 55:1350-1359.
    • (2006) Gut , vol.55 , pp. 1350-1359
    • Manns, M.P.1    Wedemeyer, H.2    Cornberg, M.3
  • 54
    • 33751223214 scopus 로고    scopus 로고
    • Hepatitis C virus entry requires a critical postinternalization step and delivery to early endosomes via clathrin-coated vesicles
    • Meertens L., Bertaux C., Dragic T. Hepatitis C virus entry requires a critical postinternalization step and delivery to early endosomes via clathrin-coated vesicles. J. Virol. 2006, 80:11571-11578.
    • (2006) J. Virol. , vol.80 , pp. 11571-11578
    • Meertens, L.1    Bertaux, C.2    Dragic, T.3
  • 57
    • 62049083697 scopus 로고    scopus 로고
    • Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well
    • Mondal R., Koev G., Pilot-Matias T., He Y., Ng T., Kati W., Molla A. Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well. Antiviral Res. 2009, 82:82-88.
    • (2009) Antiviral Res. , vol.82 , pp. 82-88
    • Mondal, R.1    Koev, G.2    Pilot-Matias, T.3    He, Y.4    Ng, T.5    Kati, W.6    Molla, A.7
  • 59
    • 0842285751 scopus 로고    scopus 로고
    • Total synthesis of the boron-containing ion carrier antibiotic macrodiolide tartrolon B
    • Mulzer J., Berger M. Total synthesis of the boron-containing ion carrier antibiotic macrodiolide tartrolon B. J. Org. Chem. 2004, 69:891-898.
    • (2004) J. Org. Chem. , vol.69 , pp. 891-898
    • Mulzer, J.1    Berger, M.2
  • 60
    • 43949087893 scopus 로고    scopus 로고
    • Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin
    • Nahmias Y., Goldwasser J., Casali M., van Poll D., Wakita T., Chung R.T., Yarmush M.L. Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin. Hepatology 2008, 47:1437-1445.
    • (2008) Hepatology , vol.47 , pp. 1437-1445
    • Nahmias, Y.1    Goldwasser, J.2    Casali, M.3    van Poll, D.4    Wakita, T.5    Chung, R.T.6    Yarmush, M.L.7
  • 67
    • 60149090028 scopus 로고    scopus 로고
    • Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
    • Ploss A., Evans M.J., Gaysinskaya V.A., Panis M., You H., de Jong Y.P., Rice C.M. Human occludin is a hepatitis C virus entry factor required for infection of mouse cells. Nature 2009, 457:882-886.
    • (2009) Nature , vol.457 , pp. 882-886
    • Ploss, A.1    Evans, M.J.2    Gaysinskaya, V.A.3    Panis, M.4    You, H.5    de Jong, Y.P.6    Rice, C.M.7
  • 68
    • 77956397284 scopus 로고    scopus 로고
    • Role of lipid metabolism in hepatitis C virus assembly and entry
    • Popescu C.I., Dubuisson J. Role of lipid metabolism in hepatitis C virus assembly and entry. Biol. Cell 2010, 102:63-74.
    • (2010) Biol. Cell , vol.102 , pp. 63-74
    • Popescu, C.I.1    Dubuisson, J.2
  • 69
    • 1642450632 scopus 로고    scopus 로고
    • Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride
    • Premkumar A., Wilson L., Ewart G.D., Gage P.W. Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride. FEBS Lett. 2004, 557:99-103.
    • (2004) FEBS Lett. , vol.557 , pp. 99-103
    • Premkumar, A.1    Wilson, L.2    Ewart, G.D.3    Gage, P.W.4
  • 70
    • 0000701347 scopus 로고    scopus 로고
    • Myxobacteria as producers of secondary metabolites
    • Springer Verlag, S. Grabley, R. Thieriecke (Eds.)
    • Reichenbach H., Höfle G. Myxobacteria as producers of secondary metabolites. Drug discovery from Nature 1999, 149-179. Springer Verlag. S. Grabley, R. Thieriecke (Eds.).
    • (1999) Drug discovery from Nature , pp. 149-179
    • Reichenbach, H.1    Höfle, G.2
  • 71
    • 37549043848 scopus 로고    scopus 로고
    • Discovery and development of the epothilones: a novel class of antineoplastic drugs
    • Reichenbach H., Höfle G. Discovery and development of the epothilones: a novel class of antineoplastic drugs. Drugs R.D. 2008, 9:1-10.
    • (2008) Drugs R.D. , vol.9 , pp. 1-10
    • Reichenbach, H.1    Höfle, G.2
  • 72
    • 61449164033 scopus 로고    scopus 로고
    • RNAither, an automated pipeline for the statistical analysis of high-throughput RNAi screens
    • Rieber N., Knapp B., Eils R., Kaderali L. RNAither, an automated pipeline for the statistical analysis of high-throughput RNAi screens. Bioinformatics 2009, 25:678-679.
    • (2009) Bioinformatics , vol.25 , pp. 678-679
    • Rieber, N.1    Knapp, B.2    Eils, R.3    Kaderali, L.4
  • 74
    • 0033779074 scopus 로고    scopus 로고
    • Tubulysins, new cytostatic peptides from myxobacteria acting on microtubuli. Production, isolation, physico-chemical and biological properties
    • Sasse F., Steinmetz H., Heil J., Hofle G., Reichenbach H. Tubulysins, new cytostatic peptides from myxobacteria acting on microtubuli. Production, isolation, physico-chemical and biological properties. J. Antibiot. (Tokyo) 2000, 53:879-885.
    • (2000) J. Antibiot. (Tokyo) , vol.53 , pp. 879-885
    • Sasse, F.1    Steinmetz, H.2    Heil, J.3    Hofle, G.4    Reichenbach, H.5
  • 77
    • 33748969698 scopus 로고    scopus 로고
    • Antibiotics from gliding bacteria, LXXV: Absolute configuration and biosynthesis of tartrolon B, a boron-containing macrodiolide from Sorangium cellulosum
    • Schummer D., Schomburg D., Irschik H., Reichenbach H., Höfle G. Antibiotics from gliding bacteria, LXXV: Absolute configuration and biosynthesis of tartrolon B, a boron-containing macrodiolide from Sorangium cellulosum. Liebigs Ann. 1996, 965-969.
    • (1996) Liebigs Ann. , pp. 965-969
    • Schummer, D.1    Schomburg, D.2    Irschik, H.3    Reichenbach, H.4    Höfle, G.5
  • 78
    • 0036829816 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis C
    • Seeff L.B. Natural history of chronic hepatitis C. Hepatology 2002, 36:S35-S46.
    • (2002) Hepatology , vol.36
    • Seeff, L.B.1
  • 80
    • 47049115607 scopus 로고    scopus 로고
    • Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles
    • Steinmann E., Brohm C., Kallis S., Bartenschlager R., Pietschmann T. Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles. J. Virol. 2008, 82:7034-7046.
    • (2008) J. Virol. , vol.82 , pp. 7034-7046
    • Steinmann, E.1    Brohm, C.2    Kallis, S.3    Bartenschlager, R.4    Pietschmann, T.5
  • 84
    • 32444435210 scopus 로고    scopus 로고
    • Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry
    • Tscherne D.M., Jones C.T., Evans M.J., Lindenbach B.D., McKeating J.A., Rice C.M. Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry. J. Virol. 2006, 80:1734-1741.
    • (2006) J. Virol. , vol.80 , pp. 1734-1741
    • Tscherne, D.M.1    Jones, C.T.2    Evans, M.J.3    Lindenbach, B.D.4    McKeating, J.A.5    Rice, C.M.6
  • 85
    • 14844337450 scopus 로고    scopus 로고
    • High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I
    • Voisset C., Callens N., Blanchard E., Op De Beeck A., Dubuisson J., Vu-Dac N. High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I. J. Biol. Chem. 2005, 280:7793-7799.
    • (2005) J. Biol. Chem. , vol.280 , pp. 7793-7799
    • Voisset, C.1    Callens, N.2    Blanchard, E.3    Op De Beeck, A.4    Dubuisson, J.5    Vu-Dac, N.6
  • 88
    • 18944366522 scopus 로고    scopus 로고
    • Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication
    • Wang C., Gale M., Keller B.C., Huang H., Brown M.S., Goldstein J.L., Ye J. Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. Mol. Cell 2005, 18:425-434.
    • (2005) Mol. Cell , vol.18 , pp. 425-434
    • Wang, C.1    Gale, M.2    Keller, B.C.3    Huang, H.4    Brown, M.S.5    Goldstein, J.L.6    Ye, J.7
  • 89
    • 77649132408 scopus 로고    scopus 로고
    • Alisporivir, a cyclosporin derivative that selectively inhibits cyclophilin, for the treatment of HCV infection
    • Watashi K. Alisporivir, a cyclosporin derivative that selectively inhibits cyclophilin, for the treatment of HCV infection. Curr. Opin. Investig. Drugs 2010, 11:213-224.
    • (2010) Curr. Opin. Investig. Drugs , vol.11 , pp. 213-224
    • Watashi, K.1
  • 90
    • 65949116191 scopus 로고    scopus 로고
    • Myxobacteria - 'microbial factories' for the production of bioactive secondary metabolites
    • Wenzel S.C., Müller R. Myxobacteria - 'microbial factories' for the production of bioactive secondary metabolites. Mol. Biosyst. 2009, 5:567-574.
    • (2009) Mol. Biosyst. , vol.5 , pp. 567-574
    • Wenzel, S.C.1    Müller, R.2
  • 91
    • 28544434492 scopus 로고    scopus 로고
    • CCR5 antagonists: host-targeted antivirals for the treatment of HIV infection
    • Westby M., van der Ryst E. CCR5 antagonists: host-targeted antivirals for the treatment of HIV infection. Antivir. Chem. Chemother. 2005, 16:339-354.
    • (2005) Antivir. Chem. Chemother. , vol.16 , pp. 339-354
    • Westby, M.1    van der Ryst, E.2
  • 92
    • 77951157311 scopus 로고    scopus 로고
    • CCR5 antagonists: host-targeted antiviral agents for the treatment of HIV infection, 4 years on
    • Westby M., van der Ryst E. CCR5 antagonists: host-targeted antiviral agents for the treatment of HIV infection, 4 years on. Antivir. Chem. Chemother. 2010, 20:179-192.
    • (2010) Antivir. Chem. Chemother. , vol.20 , pp. 179-192
    • Westby, M.1    van der Ryst, E.2
  • 93
    • 55249090938 scopus 로고    scopus 로고
    • A dynamic view of hepatitis C virus replication complexes
    • Wölk B., Büchele B., Moradpour D., Rice C.M. A dynamic view of hepatitis C virus replication complexes. J. Virol. 2008, 82:10519-10531.
    • (2008) J. Virol. , vol.82 , pp. 10519-10531
    • Wölk, B.1    Büchele, B.2    Moradpour, D.3    Rice, C.M.4
  • 94
    • 34548420660 scopus 로고    scopus 로고
    • Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus
    • Ye J. Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus. PLoS Pathog. 2007, 3:e108.
    • (2007) PLoS Pathog. , vol.3
    • Ye, J.1
  • 95
    • 0346103657 scopus 로고    scopus 로고
    • Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation
    • Ye J., Wang C., Sumpter R., Brown M.S., Goldstein J.L., Gale M. Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:15865-15870.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 15865-15870
    • Ye, J.1    Wang, C.2    Sumpter, R.3    Brown, M.S.4    Goldstein, J.L.5    Gale, M.6


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