Identification of novel epoxide inhibitors of hepatitis C virus replication using a high-throughput screen

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 10, 2007, Pages 3756-3759

  Peng, Lee F ^a,b,c   Sun, Suk Kim ^a,d   Matchacheep, Sirinya ^b,c   Lei, Xiaoguang ^e   Su, Shun ^e   Lin, Wenyu ^a   Runguphan, Weerawat ^b,c   Choe, Won Hyeok ^a   Sakamoto, Naoya ^f   Ikeda, Masanori ^g   Kato, Nobuyuki ^g   Beeler, Aaron B ^e   Porco Jr , John A ^e   Schreiber, Stuart L ^b,c,h   Chung, Raymond T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d Gachon University   (South Korea)

^e Boston University   (United States)

^f Tokyo Medical and Dental University ^*  (Japan)

^g OKAYAMA UNIVERSITY   (Japan)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUCMLD B10A11; PEGINTERFERON; RIBAVIRIN; SM A14B5; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS C VIRUS; HIGH THROUGHPUT SCREENING; NONHUMAN; PRIORITY JOURNAL; REPLICON; STRUCTURE ACTIVITY RELATION; VIRUS REPLICATION;

ANTIVIRAL AGENTS; COMPUTER SIMULATION; CYTOPATHOGENIC EFFECT, VIRAL; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; EPOXY COMPOUNDS; HEPACIVIRUS; MALEIMIDES; REPLICON; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 34948838880     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00233-07     Document Type: Article

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