The effects of mitogen-activated protein Kinase inhibitors or small interfering rnas on gallic acid-induced HeLa cell death in relation to reactive oxygen species and glutathione

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 2, 2011, Pages 763-771

  You, Bo Ra ^a   Park, Woo Hyun ^a  

^a Chonbuk National University   (South Korea)

Author keywords

apoptosis; Gallic acid; GSH; MAPK inhibitor; ROS

Indexed keywords

APOPTOSIS; GALLIC ACIDS; GSH; MAPK INHIBITOR; ROS;

CELL DEATH; CELL GROWTH; CELL MEMBRANES; ENZYME ACTIVITY; GROWTH KINETICS; OXYGEN; RNA;

ECOLOGY;

GALLIC ACID; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ARTICLE; CELL DEATH; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETICS; HELA CELL; HUMAN; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; UTERINE CERVIX TUMOR;

CELL DEATH; FEMALE; GALLIC ACID; GLUTATHIONE; HELA CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; UTERINE CERVICAL NEOPLASMS;

EID: 78751536677     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf103379d     Document Type: Article

References (46)

1. Niemetz, R.; Gross, G. G. Enzymology of gallotannin and ellagitannin biosynthesis Phytochemistry 2005, 66 (17) 2001-2011
2. Shahrzad, S.; Aoyagi, K.; Winter, A.; Koyama, A.; Bitsch, I. Pharmacokinetics of gallic acid and its relative bioavailability from tea in healthy humans J. Nutr. 2001, 131 (4) 1207-1210
3. Kang, M. S.; Oh, J. S.; Kang, I. C.; Hong, S. J.; Choi, C. H. Inhibitory effect of methyl gallate and gallic acid on oral bacteria J. Microbiol. 2008, 46 (6) 744-750
4. Kratz, J. M.; Andrighetti-Frohner, C. R.; Leal, P. C.; Nunes, R. J.; Yunes, R. A.; Trybala, E.; Bergstrom, T.; Barardi, C. R.; Simoes, C. M. Evaluation of anti-HSV-2 activity of gallic acid and pentyl gallate Biol. Pharm. Bull. 2008, 31 (5) 903-907
5. Kim, S. H.; Jun, C. D.; Suk, K.; Choi, B. J.; Lim, H.; Park, S.; Lee, S. H.; Shin, H. Y.; Kim, D. K.; Shin, T. Y. Gallic acid inhibits histamine release and pro-inflammatory cytokine production in mast cells Toxicol. Sci. 2006, 91 (1) 123-131
6. Kaur, M.; Velmurugan, B.; Rajamanickam, S.; Agarwal, R.; Agarwal, C. Gallic acid, an active constituent of grape seed extract, exhibits anti-proliferative, pro-apoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth in nude mice Pharm. Res. 2009, 26 (9) 2133-2140
7. Kawada, M.; Ohno, Y.; Ri, Y.; Ikoma, T.; Yuugetu, H.; Asai, T.; Watanabe, M.; Yasuda, N.; Akao, S.; Takemura, G.; Minatoguchi, S.; Gotoh, K.; Fujiwara, H.; Fukuda, K. Anti-tumor effect of gallic acid on LL-2 lung cancer cells transplanted in mice Anticancer Drugs 2001, 12 (10) 847-852
8. Ohno, Y.; Fukuda, K.; Takemura, G.; Toyota, M.; Watanabe, M.; Yasuda, N.; Xinbin, Q.; Maruyama, R.; Akao, S.; Gotou, K.; Fujiwara, T.; Fujiwara, H. Induction of apoptosis by gallic acid in lung cancer cells Anticancer Drugs 1999, 10 (9) 845-851
9. You, B. R.; Park, W. H. Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase Toxicol in Vitro 2010, 24 (5) 1356-1362
10. Faried, A.; Kurnia, D.; Faried, L. S.; Usman, N.; Miyazaki, T.; Kato, H.; Kuwano, H. Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines Int. J. Oncol. 2007, 30 (3) 605-613
11. Chen, H. M.; Wu, Y. C.; Chia, Y. C.; Chang, F. R.; Hsu, H. K.; Hsieh, Y. C.; Chen, C. C.; Yuan, S. S. Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells Cancer Lett. 2009, 286 (2) 161-171
12. Inoue, M.; Sakaguchi, N.; Isuzugawa, K.; Tani, H.; Ogihara, Y. Role of reactive oxygen species in gallic acid-induced apoptosis Biol. Pharm. Bull. 2000, 23 (10) 1153-1157
13. Strlic, M.; Radovic, T.; Kolar, J.; Pihlar, B. Anti- and prooxidative properties of gallic acid in fenton-type systems J. Agric. Food Chem. 2002, 50 (22) 6313-6317
14. Sakagami, H.; Satoh, K. Prooxidant action of two antioxidants: Ascorbic acid and gallic acid Anticancer Res. 1997, 17 (1A) 221-224
15. Gonzalez, C.; Sanz-Alfayate, G.; Agapito, M. T.; Gomez-Nino, A.; Rocher, A.; Obeso, A. Significance of ROS in oxygen sensing in cell systems with sensitivity to physiological hypoxia Respir. Physiol. Neurobiol. 2002, 132 (1) 17-41
16. Baran, C. P.; Zeigler, M. M.; Tridandapani, S.; Marsh, C. B. The role of ROS and RNS in regulating life and death of blood monocytes Curr. Pharm. Des. 2004, 10 (8) 855-866
17. Wallach-Dayan, S. B.; Izbicki, G.; Cohen, P. Y.; Gerstl-Golan, R.; Fine, A.; Breuer, R. Bleomycin initiates apoptosis of lung epithelial cells by ROS but not by Fas/FasL pathway Am. J. Physiol. Lung Cell Mol. Physiol. 2006, 290 (4) L790-L796
18. Simon, H. U.; Haj-Yehia, A.; Levi-Schaffer, F. Role of reactive oxygen species (ROS) in apoptosis induction Apoptosis 2000, 5 (5) 415-418
19. Genestra, M. Oxyl radicals, redox-sensitive signalling cascades and antioxidants Cell Signalling 2007, 19 (9) 1807-1819
20. Blenis, J. Signal transduction via the MAP kinases: Proceed at your own RSK Proc. Natl. Acad. Sci. U.S.A. 1993, 90 (13) 5889-5892
21. Kusuhara, M.; Takahashi, E.; Peterson, T. E.; Abe, J.; Ishida, M.; Han, J.; Ulevitch, R.; Berk, B. C. p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: Effects on Na+/H+ exchange and ERK1/2 Circ. Res. 1998, 83 (8) 824-831
22. Hsin, Y. H.; Chen, C. F.; Huang, S.; Shih, T. S.; Lai, P. S.; Chueh, P. J. The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells Toxicol. Lett. 2008, 179 (3) 130-139
23. Mao, X.; Yu, C. R.; Li, W. H.; Li, W. X. Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells Cell Res 2008, 18 (8) 879-888
24. Gomez-Lazaro, M.; Galindo, M. F.; Melero-Fernandez de Mera, R. M.; Fernandez-Gomez, F. J.; Concannon, C. G.; Segura, M. F.; Comella, J. X.; Prehn, J. H.; Jordan, J. Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate Mol. Pharmacol. 2007, 71 (3) 736-743
25. Guyton, K. Z.; Liu, Y.; Gorospe, M.; Xu, Q.; Holbrook, N. J. Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury J. Biol. Chem. 1996, 271 (8) 4138-4142
26. Liu, Y.; Borchert, G. L.; Surazynski, A.; Hu, C. A.; Phang, J. M. Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling Oncogene 2006, 25 (41) 5640-5647
27. Henson, E. S.; Gibson, S. B. Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: Implications for cancer therapy Cell Signalling 2006, 18 (12) 2089-2097
28. You, B. R.; Moon, H. J.; Han, Y. H.; Park, W. H. Gallic acid inhibits the growth of HeLa cervical cancer cells via apoptosis and/or necrosis Food Chem. Toxicol. 2010, 48 (5) 1334-1340
29. Han, Y. H.; Moon, H. J.; You, B. R.; Kim, S. Z.; Kim, S. H.; Park, W. H. JNK and p38 inhibitors increase and decrease apoptosis, respectively, in pyrogallol-treated calf pulmonary arterial endothelial cells Int. J. Mol. Med. 2009, 24 (5) 717-722
30. Park, W. H.; Seol, J. G.; Kim, E. S.; Hyun, J. M.; Jung, C. W.; Lee, C. C.; Kim, B. K.; Lee, Y. Y. Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis Cancer Res. 2000, 60 (11) 3065-3071
31. Han, Y. H.; Kim, S. W.; Kim, S. H.; Kim, S. Z.; Park, W. H. 2,4-dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells Toxicol in Vitro 2008, 22 (3) 659-670
32. Han, Y. H.; Kim, S. Z.; Kim, S. H.; Park, W. H. Arsenic trioxide inhibits growth of As4.1 juxtaglomerular cells via cell cycle arrest and caspase-independent apoptosis Am. J. Physiol. 2007, 293 (2) F511-F520
33. Han, Y. H.; Kim, S. H.; Kim, S. Z.; Park, W. H. Caspase inhibitor decreases apoptosis in pyrogallol-treated lung cancer Calu-6 cells via the prevention of GSH depletion Int. J. Oncol. 2008, 33 (5) 1099-1105
34. Elbashir, S. M.; Harborth, J.; Lendeckel, W.; Yalcin, A.; Weber, K.; Tuschl, T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 2001, 411 (6836) 494-498
35. Bain, J.; McLauchlan, H.; Elliott, M.; Cohen, P. The specificities of protein kinase inhibitors: An update Biochem. J. 2003, 371 (Part 1) 199-204
36. Rygiel, T. P.; Mertens, A. E.; Strumane, K.; van der Kammen, R.; Collard, J. G. The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation J. Cell Sci. 2008, 121 (Part 8) 1183-1192
37. Han, Y. H.; Moon, H. J.; You, B. R.; Yang, Y. M.; Kim, S. Z.; Kim, S. H.; Park, W. H. The MEK inhibitor PD98059 attenuates growth inhibition and death in gallic acid-treated Calu-6 lung cancer cells by preventing glutathione depletion Mol. Med. Rep. 2010, 3 (3) 519-524
38. Park, W. H. MAPK inhibitors differentially affect gallic acid-induced human pulmonary fibroblast cell growth inhibition Mol. Med. Rep. 2011, 4 (1) 193-197
39. Carnero, A. The PKB/AKT pathway in cancer Curr. Pharm. Des. 2010, 16 (1) 34-44
40. Dillon, R. L.; Muller, W. J. Distinct biological roles for the akt family in mammary tumor progression Cancer Res. 2010, 70 (11) 4260-4264
41. Kang, M. K.; Kang, N. J.; Jang, Y. J.; Lee, K. W.; Lee, H. J. Gallic acid induces neuronal cell death through activation of c-Jun N-terminal kinase and downregulation of Bcl-2 Ann. N. Y. Acad. Sci. 2009, 1171, 514-520
42. Yang, Y. M.; Park, W. H. p38 inhibitor enhances growth inhibition and death in gallic acid-treated endothelial cells Int. J. Mol. Med. 2010, 26 (2) 295-300
43. Marshall, N. J.; Goodwin, C. J.; Holt, S. J. A critical assessment of the use of microculture tetrazolium assays to measure cell growth and function Growth Regul. 1995, 5 (2) 69-84
44. Serrano, A.; Palacios, C.; Roy, G.; Cespon, C.; Villar, M. L.; Nocito, M.; Gonzalez-Porque, P. Derivatives of gallic acid induce apoptosis in tumoral cell lines and inhibit lymphocyte proliferation Arch. Biochem. Biophys. 1998, 350 (1) 49-54
45. Poot, M.; Teubert, H.; Rabinovitch, P. S.; Kavanagh, T. J. De novo synthesis of glutathione is required for both entry into and progression through the cell cycle J. Cell. Physiol. 1995, 163 (3) 555-560
46. Schnelldorfer, T.; Gansauge, S.; Gansauge, F.; Schlosser, S.; Beger, H. G.; Nussler, A. K. Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells Cancer 2000, 89 (7) 1440-1447