The MEK inhibitor PD98059 attenuates growth inhibition and death in gallic acid-treated Calu-6 lung cancer cells by preventing glutathione depletion

Molecular Medicine Reports

Volumn 3, Issue 3, 2010, Pages 519-524

  Yong, Hwan Han ^a   Hwa, Jin Moon ^a   You, Bo Ra ^a   Yang, Yeon Mi ^a   Sung, Zoo Kim ^a   Suhn, Hee Kim ^a   Woo, Hyun Park ^a  

^a Chonbuk National University   (South Korea)

Author keywords

Apoptosis; Calu 6; Cell death; Gallic acid; Mitogen activated protein kinase; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GALLIC ACID; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ATTENUATION; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL GROWTH; CELL LOSS; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN DEPLETION;

EID: 77952404403     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr-00000291     Document Type: Article

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