Design and development of gliclazide-loaded chitosan microparticles for oral sustained drug delivery: In-vitro/in-vivo evaluation

Journal of Pharmacy and Pharmacology

Volumn 63, Issue 2, 2011, Pages 169-178

  Barakat, Nahla S ^a   Almurshedi, Alanood S ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

chitosan; gliclazide; microparticles; pectin; sustained release

Indexed keywords

CHITOSAN; GLICLAZIDE; GLUTARALDEHYDE; PECTIN; TRIPOLYPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG DESIGN; EMULSION; GLUCOSE BLOOD LEVEL; INFRARED SPECTROSCOPY; MALE; NONHUMAN; PARTICLE SIZE; RABBIT; SCANNING ELECTRON MICROSCOPY; STREPTOZOCIN DIABETES; SUSTAINED DRUG RELEASE;

ADMINISTRATION, ORAL; ANIMALS; BLOOD GLUCOSE; CALORIMETRY, DIFFERENTIAL SCANNING; CHITOSAN; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; DRUG DESIGN; GLICLAZIDE; GLUTARAL; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS; MALE; MICROSPHERES; PARTICLE SIZE; PECTINS; POLYPHOSPHATES; POWDERS; RABBITS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TABLETS;

EID: 78751517359     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2010.01214.x     Document Type: Article

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