Development of mucoadhesive microspheres of acyclovir with enhanced bioavailability

International Journal of Pharmaceutics

Volumn 378, Issue 1-2, 2009, Pages 30-36

  Tao, Yunying ^a   Lu, Yifan ^a   Sun, Yinjing ^a   Gu, Bing ^a   Lu, Weiyue ^a   Pan, Jun ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Acyclovir; Bioavailability; Mucoadhesion; Mucoadhesive microspheres

Indexed keywords

ACICLOVIR; CARBOPOL 974P; ETHYL CELLULOSE; MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG RELEASE; DRUG RETENTION; ENCAPSULATION; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MOUSE; MUCOADHESION; NONHUMAN; PH; PRIORITY JOURNAL; RAT; STOMACH MUCOSA; SUSPENSION;

ACRYLATES; ACYCLOVIR; ADHESIVENESS; ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CELLULOSE; EGG SHELL; EXCIPIENTS; GASTRIC MUCOSA; HYDROGEN-ION CONCENTRATION; MICROSCOPY; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MODELS, BIOLOGICAL; RATS; RATS, WISTAR;

EID: 67650635130     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.05.025     Document Type: Article

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