Novel pH-sensitive citrate cross-linked chitosan film for drug controlled release

International Journal of Pharmaceutics

Volumn 212, Issue 1, 2001, Pages 19-28

  Shu, X Z ^a   Zhu, K J ^a   Song, Weihong ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Chitosan film; Drug controlled release; PH sensitive; Sodium citrate

Indexed keywords

ALGINIC ACID; BRILLIANT BLUE; CHITOSAN; CITRIC ACID; HEPARIN; PECTIN; RIBOFLAVIN; SODIUM CHLORIDE;

ANALYTIC METHOD; ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; DRUG COATING; DRUG STRUCTURE; ELECTRICITY; INTESTINE FLUID; IONIC STRENGTH; IONIZATION; PH; PRIORITY JOURNAL; STOMACH JUICE; TITRIMETRY; TURBIDITY;

CHITIN; CHITOSAN; CITRIC ACID; DRUG DELIVERY SYSTEMS; HYDROGEN-ION CONCENTRATION; SODIUM CHLORIDE;

EID: 0035808267     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00582-2     Document Type: Article

References (26)

1. Evaluation of parameters involved in preparation and release of drug loaded in cross-linked matrices of alginate
2. Preparation and properties of modified chitosan films for drug release
3. Study of the stoichiometric polyelectrolyte complex between chitosan and carboxylmethyl cellulose
4. Chitosan matrix for oral sustained delivery of ampicillin
5. pH-sensitive swelling of a polyelectrolyte complex gel prepared from xanthan and chitosan
6. Colorimetric method for determination of sugars and related substances
7. Drug release behaviors of beads and microgranules of chitosan
8. Chitosan and its use as a pharmaceutical excipient
9. Method for analyzing pH-sensitive swelling of amphoteric hydrogels - Application to a polyelectrolyte complex gel prepared from xanthan and chitosan
10. Buoyant sustained release tablets based on chitosan
11. Polyelectrolyte complexes of heparin with chitosan
12. The potential use of mixed films of pectin, chitosan and HPMC for bimodal drug release
13. Protein-polyelectrolyte phase boundaries
14. Permeability of vitamin B-12 in chitosan membranes. Effect of cross-linking and blending with poly(vinyl alcohol) on permeability
15. Effects of protein charge heterogeneity in protein-polyelectrolyte complexation
16. Preparation of characterization of freeze-dried chitosan-poly(ethylene oxide) hydrogels for site-specific antibiotic delivery in the stomach
17. Mechanical, water uptake and permeability properties of cross-linked chitosan glutamate and alginate films
18. A novel approach to prepare tripolyphosphate/chitosan complex beads for controlled release drug delivery
19. Chitosan/gelatin microspheres prepared by modified emulsification and ionotropic gelation
20. Propranolol hydrochloride release behavior of cross-linked chitosan membranes
21. Alginate polycation microcapsules II. Some functional properties
22. Some chemical and analytical aspects of polysaccharide modification. 3. Formation of branched-chain, soluble chitosan derivatives
23. pH-sensitivity of hydrogel based on complex-forming chitosan: Polyether interpenetrating polymer network
24. Microcapsules/microspheres related to chitosan
25. Swelling behavior of pectin/chitosan complex films
26. Acid-induced and calcium-induced gelation of alginic acid: Bead formation and pH-dependent swelling