메뉴 건너뛰기




Volumn 24, Issue 1, 2011, Pages 89-106

A neuroendocrinological perspective on human hair follicle pigmentation

Author keywords

ACTH; Alpha MSH; CRH; Greying; Melanin; Melanocyte stem cell

Indexed keywords

ALPHA INTERMEDIN; AUTOANTIGEN; BETA ENDORPHIN; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; MELATONIN; NEUROHORMONE; NEUROPEPTIDE; PROTIRELIN; REACTIVE OXYGEN METABOLITE;

EID: 78651429942     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00808.x     Document Type: Article
Times cited : (56)

References (149)
  • 1
    • 77954853515 scopus 로고    scopus 로고
    • The cycling hair follicle as an ideal systems biology research model
    • Al-Nuaimi, Y., Baier, G., Watson, R.E., Chuong, C.M., and Paus, R. (2010). The cycling hair follicle as an ideal systems biology research model. Exp. Dermatol. 19, 707-713.
    • (2010) Exp. Dermatol. , vol.19 , pp. 707-713
    • Al-Nuaimi, Y.1    Baier, G.2    Watson, R.E.3    Chuong, C.M.4    Paus, R.5
  • 2
    • 0041562601 scopus 로고    scopus 로고
    • Intermittent foot shock stress prolongs the telogen stage in the hair cycle of mice
    • Aoki, E., Shibasaki, T., and Kawana, S. (2003). Intermittent foot shock stress prolongs the telogen stage in the hair cycle of mice. Exp. Dermatol. 12, 371-377.
    • (2003) Exp. Dermatol. , vol.12 , pp. 371-377
    • Aoki, E.1    Shibasaki, T.2    Kawana, S.3
  • 3
    • 0037370738 scopus 로고    scopus 로고
    • Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathways
    • Arck, P.C., Handjiski, B., Peters, E.M., Peter, A.S., Hagen, E., Fischer, A., Klapp, B.F., and Paus, R. (2003). Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathways. Am. J. Pathol. 162, 803-814.
    • (2003) Am. J. Pathol. , vol.162 , pp. 803-814
    • Arck, P.C.1    Handjiski, B.2    Peters, E.M.3    Peter, A.S.4    Hagen, E.5    Fischer, A.6    Klapp, B.F.7    Paus, R.8
  • 4
    • 23044509166 scopus 로고    scopus 로고
    • Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition
    • Arck, P.C., Handjiski, B., Kuhlmei, A., Peters, E.M., Knackstedt, M., Peter, A., Hunt, S.P., Klapp, B.F., and Paus, R. (2005). Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition. J. Mol. Med. 83, 386-396.
    • (2005) J. Mol. Med. , vol.83 , pp. 386-396
    • Arck, P.C.1    Handjiski, B.2    Kuhlmei, A.3    Peters, E.M.4    Knackstedt, M.5    Peter, A.6    Hunt, S.P.7    Klapp, B.F.8    Paus, R.9
  • 5
    • 33845600767 scopus 로고    scopus 로고
    • Towards a "free radical theory of graying": melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage
    • Arck, P.C., Overall, R., Spatz, K., Liezman, C., Handjiski, B., Klapp, B.F., Birch- Machin, M.A., and Peters, E.M. (2006a). Towards a "free radical theory of graying": melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage. FASEB J. 20, 1567-1569.
    • (2006) FASEB J. , vol.20 , pp. 1567-1569
    • Arck, P.C.1    Overall, R.2    Spatz, K.3    Liezman, C.4    Handjiski, B.5    Klapp, B.F.6    Birch- Machin, M.A.7    Peters, E.M.8
  • 7
    • 0030218918 scopus 로고    scopus 로고
    • The genetics of pigmentation: from fancy genes to complex traits
    • Barsh, G.S. (1996). The genetics of pigmentation: from fancy genes to complex traits. Trends Genet. 12, 299-305.
    • (1996) Trends Genet. , vol.12 , pp. 299-305
    • Barsh, G.S.1
  • 8
    • 57349087307 scopus 로고    scopus 로고
    • Thyroid hormones directly alter human hair follicle functions: anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation
    • van Beek, N., Bodó, E., Kromminga, A., Gáspár, E., Meyer, K., Zmijewski, M.A., Slominski, A., Wenzel, B.E., and Paus, R. (2008). Thyroid hormones directly alter human hair follicle functions: anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation. J. Clin. Endocrinol. Metab. 93, 4381-4388.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 4381-4388
    • van Beek, N.1    Bodó, E.2    Kromminga, A.3    Gáspár, E.4    Meyer, K.5    Zmijewski, M.A.6    Slominski, A.7    Wenzel, B.E.8    Paus, R.9
  • 9
    • 0015131083 scopus 로고
    • A biologist's reflections on dermatology
    • Billingham, R.E., and Silvers, W.K. (1971). A biologist's reflections on dermatology. J. Invest. Dermatol. 57, 227-240.
    • (1971) J. Invest. Dermatol. , vol.57 , pp. 227-240
    • Billingham, R.E.1    Silvers, W.K.2
  • 10
    • 35348890110 scopus 로고    scopus 로고
    • Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy
    • Bodó, E., Tobin, D.J., Kamenisch, Y., Bíró, T., Berneburg, M., Funk, W., and Paus, R. (2007). Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy. Am. J. Pathol. 171, 1153-1167.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1153-1167
    • Bodó, E.1    Tobin, D.J.2    Kamenisch, Y.3    Bíró, T.4    Berneburg, M.5    Funk, W.6    Paus, R.7
  • 12
    • 77950292460 scopus 로고    scopus 로고
    • Thyroid-stimulating hormone, a novel, locally produced modulator of human epidermal functions, is regulated by thyrotropin-releasing hormone and thyroid hormones
    • Bodó, E., Kany, B., Gáspár, E. et al. (2010). Thyroid-stimulating hormone, a novel, locally produced modulator of human epidermal functions, is regulated by thyrotropin-releasing hormone and thyroid hormones. Endocrinology 151, 1633-1642.
    • (2010) Endocrinology , vol.151 , pp. 1633-1642
    • Bodó, E.1    Kany, B.2    Gáspár, E.3
  • 13
    • 0035088316 scopus 로고    scopus 로고
    • SCF/c-kit signaling is required for cyclic regeneration of the hair pigmentation unit
    • Botchkareva, N.V., Khlgatian, M., Longley, B.J., Botchkarev, V.A., and Gilchrest, B.A. (2001). SCF/c-kit signaling is required for cyclic regeneration of the hair pigmentation unit. FASEB J. 15, 645-658.
    • (2001) FASEB J. , vol.15 , pp. 645-658
    • Botchkareva, N.V.1    Khlgatian, M.2    Longley, B.J.3    Botchkarev, V.A.4    Gilchrest, B.A.5
  • 14
    • 0003543106 scopus 로고    scopus 로고
    • Skin Signs of Systemic Disease
    • 3rd edn. (Philadelphia: Saunders).
    • Braverman, I. (1998). Skin Signs of Systemic Disease, 3rd edn. (Philadelphia: Saunders).
    • (1998)
    • Braverman, I.1
  • 15
    • 49449094104 scopus 로고    scopus 로고
    • Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases
    • Brzoska, T., Luger, T.A., Maaser, C., Abels, C., and Böhm, M. (2008). Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases. Endocr. Rev. 29, 581-602.
    • (2008) Endocr. Rev. , vol.29 , pp. 581-602
    • Brzoska, T.1    Luger, T.A.2    Maaser, C.3    Abels, C.4    Böhm, M.5
  • 18
    • 1842558949 scopus 로고    scopus 로고
    • Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheath
    • Commo, S., Gaillard, O., and Bernard, B.A. (2004). Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheath. Br. J. Dermatol. 150, 435-443.
    • (2004) Br. J. Dermatol. , vol.150 , pp. 435-443
    • Commo, S.1    Gaillard, O.2    Bernard, B.A.3
  • 19
    • 42149099446 scopus 로고    scopus 로고
    • Impact of homozygosity of R151C variant of MC1r in human hair follicle melanocytes
    • Commo, S.F., Gaillard, O., Rees, J.L., and Bernard, B.A. (2008). Impact of homozygosity of R151C variant of MC1r in human hair follicle melanocytes. J. Invest. Dermatol. 128, 1319-1322.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 1319-1322
    • Commo, S.F.1    Gaillard, O.2    Rees, J.L.3    Bernard, B.A.4
  • 20
    • 31044432919 scopus 로고    scopus 로고
    • Gene expression profiling gets to the root of human hair follicle stem cells
    • Cotsarelis, G. (2006). Gene expression profiling gets to the root of human hair follicle stem cells. J. Clin. Invest. 116, 19-22.
    • (2006) J. Clin. Invest. , vol.116 , pp. 19-22
    • Cotsarelis, G.1
  • 21
    • 0025740692 scopus 로고
    • Role of hair follicles in the repigmentation of vitiligo
    • Cui, J., Shen, L.Y., and Wang, G.C. (1991). Role of hair follicles in the repigmentation of vitiligo. J. Invest. Dermatol. 97, 410-416.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 410-416
    • Cui, J.1    Shen, L.Y.2    Wang, G.C.3
  • 22
    • 77951749647 scopus 로고    scopus 로고
    • Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism
    • Dong, L., Wen, J., Pier, E., Zhang, X., Zhang, B., Dong, F., Ziegler, N., Mysz, M., Armenta, R., and Cui, R. (2010). Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism. Cancer Res. 70, 3547-3556.
    • (2010) Cancer Res. , vol.70 , pp. 3547-3556
    • Dong, L.1    Wen, J.2    Pier, E.3    Zhang, X.4    Zhang, B.5    Dong, F.6    Ziegler, N.7    Mysz, M.8    Armenta, R.9    Cui, R.10
  • 23
    • 2442526335 scopus 로고    scopus 로고
    • Melanocytes: morphological basis for an exteroceptive sensory system for monitoring ultraviolet radiation
    • Ericsson, A.D., Dora, J., and Cao, S. (2003). Melanocytes: morphological basis for an exteroceptive sensory system for monitoring ultraviolet radiation. Physiol. Chem. Phys. Med. NMR 35, 27-42.
    • (2003) Physiol. Chem. Phys. Med. NMR , vol.35 , pp. 27-42
    • Ericsson, A.D.1    Dora, J.2    Cao, S.3
  • 24
    • 78349302122 scopus 로고    scopus 로고
    • Stress Science: Neuroendocrinology
    • Fink, G. (ed.)(Amsterdam: Elsevier).
    • Fink, G. (ed.) (2010). Stress Science: Neuroendocrinology. (Amsterdam: Elsevier).
    • (2010)
  • 25
    • 49049087975 scopus 로고    scopus 로고
    • Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair
    • Fischer, T.W., Slominski, A., Zmijewski, M.A., Reiter, R.J., and Paus, R. (2008a). Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp. Dermatol. 17, 713-730.
    • (2008) Exp. Dermatol. , vol.17 , pp. 713-730
    • Fischer, T.W.1    Slominski, A.2    Zmijewski, M.A.3    Reiter, R.J.4    Paus, R.5
  • 27
    • 33644646083 scopus 로고    scopus 로고
    • Human scalp hair follicles are both a target and a source of prolactin, which serves as an autocrine and/or paracrine promoter of apoptosis-driven hair follicle regression
    • Foitzik, K., Krause, K., Conrad, F., Nakamura, M., Funk, W., and Paus, R. (2006). Human scalp hair follicles are both a target and a source of prolactin, which serves as an autocrine and/or paracrine promoter of apoptosis-driven hair follicle regression. Am. J. Pathol. 168, 748-756.
    • (2006) Am. J. Pathol. , vol.168 , pp. 748-756
    • Foitzik, K.1    Krause, K.2    Conrad, F.3    Nakamura, M.4    Funk, W.5    Paus, R.6
  • 29
    • 0031974909 scopus 로고    scopus 로고
    • Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice
    • Gilhar, A., Ullmann, Y., Berkutzki, T., Assy, B., and Kalish, R.S. (1998). Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice. J. Clin. Invest. 101, 62-67.
    • (1998) J. Clin. Invest. , vol.101 , pp. 62-67
    • Gilhar, A.1    Ullmann, Y.2    Berkutzki, T.3    Assy, B.4    Kalish, R.S.5
  • 30
    • 0035671174 scopus 로고    scopus 로고
    • Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdc(scid) mice
    • Gilhar, A., Landau, M., Assy, B., Shalaginov, R., Serafimovich, S., and Kalish, R.S. (2001). Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdc(scid) mice. J. Invest. Dermatol. 117, 1357-1362.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 1357-1362
    • Gilhar, A.1    Landau, M.2    Assy, B.3    Shalaginov, R.4    Serafimovich, S.5    Kalish, R.S.6
  • 31
    • 34547687736 scopus 로고    scopus 로고
    • Lymphocytes, neuropeptides, and genes involved in alopecia areata
    • Gilhar, A., Paus, R., and Kalish, R.S. (2007). Lymphocytes, neuropeptides, and genes involved in alopecia areata. J. Clin. Invest. 117, 2019-2027.
    • (2007) J. Clin. Invest. , vol.117 , pp. 2019-2027
    • Gilhar, A.1    Paus, R.2    Kalish, R.S.3
  • 32
    • 66749132873 scopus 로고    scopus 로고
    • Stem cell factor-KIT signalling plays a pivotal role in regulating pigmentation in mammalian hair
    • Hachiya, A., Sriwiriyanont, P., Kobayashi, T. et al. (2009). Stem cell factor-KIT signalling plays a pivotal role in regulating pigmentation in mammalian hair. J. Pathol. 218, 30-39.
    • (2009) J. Pathol. , vol.218 , pp. 30-39
    • Hachiya, A.1    Sriwiriyanont, P.2    Kobayashi, T.3
  • 33
    • 0014610822 scopus 로고
    • The influence of hormones on melanogenesis
    • Hall, P.F. (1969). The influence of hormones on melanogenesis. Australas. J. Dermatol. 10, 125-139.
    • (1969) Australas. J. Dermatol. , vol.10 , pp. 125-139
    • Hall, P.F.1
  • 34
    • 78149292488 scopus 로고    scopus 로고
    • The pathogenesis of primary cicatricial alopecias
    • Harries, M.J., and Paus, R. (2010). The pathogenesis of primary cicatricial alopecias. Am. J. Pathol. 177, 2152-2162.
    • (2010) Am. J. Pathol. , vol.177 , pp. 2152-2162
    • Harries, M.J.1    Paus, R.2
  • 35
    • 78651453438 scopus 로고    scopus 로고
    • Management of alopecia areata
    • c3671.
    • Harries, M.J., Sun, J., Paus, R., and King Jr, L.E. (2010). Management of alopecia areata. BMJ 23, 341. c3671. doi:
    • (2010) BMJ , vol.23 , pp. 341
    • Harries, M.J.1    Sun, J.2    Paus, R.3    King Jr, L.E.4
  • 36
    • 0021022486 scopus 로고
    • Distribution of major histocompatibility antigens in normal skin
    • Harrist, T.J., Ruiter, D.J., Mihm Jr, M.C., and Bhan, A.K. (1983). Distribution of major histocompatibility antigens in normal skin. Br. J. Dermatol. 109, 623-633.
    • (1983) Br. J. Dermatol. , vol.109 , pp. 623-633
    • Harrist, T.J.1    Ruiter, D.J.2    Mihm Jr, M.C.3    Bhan, A.K.4
  • 37
    • 34249330909 scopus 로고    scopus 로고
    • The M4 muscarinic acetylcholine receptor plays a key role in the control of murine hair follicle cycling and pigmentation
    • Hasse, S., Chernyavsky, A.I., Grando, S.A., and Paus, R. (2007). The M4 muscarinic acetylcholine receptor plays a key role in the control of murine hair follicle cycling and pigmentation. Life Sci. 80, 2248-2252.
    • (2007) Life Sci. , vol.80 , pp. 2248-2252
    • Hasse, S.1    Chernyavsky, A.I.2    Grando, S.A.3    Paus, R.4
  • 39
    • 22144461400 scopus 로고    scopus 로고
    • A guide to assessing damage response pathways of the hair follicle: lessons from cyclophosphamide-induced alopecia in mice
    • Hendrix, S., Handjiski, B., Peters, E.M., and Paus, R. (2005). A guide to assessing damage response pathways of the hair follicle: lessons from cyclophosphamide-induced alopecia in mice. J. Invest. Dermatol. 125, 42-51.
    • (2005) J. Invest. Dermatol. , vol.125 , pp. 42-51
    • Hendrix, S.1    Handjiski, B.2    Peters, E.M.3    Paus, R.4
  • 40
    • 77954487039 scopus 로고    scopus 로고
    • Estrogen increases hair pigmentation in female recessive yellow mice
    • Hirobe, T., Kiuchi, M., Wakamatsu, K., and Ito, S. (2010). Estrogen increases hair pigmentation in female recessive yellow mice. Zoolog. Sci. 27, 470-476.
    • (2010) Zoolog. Sci. , vol.27 , pp. 470-476
    • Hirobe, T.1    Kiuchi, M.2    Wakamatsu, K.3    Ito, S.4
  • 41
    • 77958539608 scopus 로고    scopus 로고
    • Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata
    • Epub ahead of print].
    • Hong-Wei, G., Jun, D., Xi-Chuan, Y., Bai-Yu, Z., Zhu, S., Shao-Yan, Y., Bao-Heng, L., and Fei, H. (2010). Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata. Exp. Dermatol. [Epub ahead of print].
    • (2010) Exp. Dermatol.
    • Hong-Wei, G.1    Jun, D.2    Xi-Chuan, Y.3    Bai-Yu, Z.4    Zhu, S.5    Shao-Yan, Y.6    Bao-Heng, L.7    Fei, H.8
  • 42
    • 66449086247 scopus 로고    scopus 로고
    • Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation
    • Inomata, K., Aoto, T., Binh, N.T. et al. (2009). Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation. Cell 137, 1088-1099.
    • (2009) Cell , vol.137 , pp. 1088-1099
    • Inomata, K.1    Aoto, T.2    Binh, N.T.3
  • 43
    • 78651449422 scopus 로고    scopus 로고
    • Human hair melanins: what we have learned and have not learned from mouse coat color pigmentation
    • Ito, S., and Wakamatsu, K. (2010). Human hair melanins: what we have learned and have not learned from mouse coat color pigmentation. Pigment Cell Melanoma Res. doi:
    • (2010) Pigment Cell Melanoma Res.
    • Ito, S.1    Wakamatsu, K.2
  • 44
    • 1642493829 scopus 로고    scopus 로고
    • The human hair bulb is a source and target of CRH
    • Ito, N., Ito, T., Betterman, A., and Paus, R. (2004a). The human hair bulb is a source and target of CRH. J. Invest. Dermatol. 122, 235-237.
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 235-237
    • Ito, N.1    Ito, T.2    Betterman, A.3    Paus, R.4
  • 45
    • 1542379709 scopus 로고    scopus 로고
    • Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model
    • Ito, T., Ito, N., Bettermann, A., Tokura, Y., Takigawa, M., and Paus, R. (2004b). Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model. Am. J. Pathol. 164, 623-634.
    • (2004) Am. J. Pathol. , vol.164 , pp. 623-634
    • Ito, T.1    Ito, N.2    Bettermann, A.3    Tokura, Y.4    Takigawa, M.5    Paus, R.6
  • 46
    • 23444462244 scopus 로고    scopus 로고
    • Human hair follicles display a functional equivalent of the hypothalamic-pituitary-adrenal axis and synthesize cortisol
    • Ito, N., Ito, T., Kromminga, A., Bettermann, A., Takigawa, M., Kees, F., Straub, R.H., and Paus, R. (2005). Human hair follicles display a functional equivalent of the hypothalamic-pituitary-adrenal axis and synthesize cortisol. FASEB J. 19, 1332-1334.
    • (2005) FASEB J. , vol.19 , pp. 1332-1334
    • Ito, N.1    Ito, T.2    Kromminga, A.3    Bettermann, A.4    Takigawa, M.5    Kees, F.6    Straub, R.H.7    Paus, R.8
  • 47
    • 77949539634 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone stimulates the in situ generation of mast cells from precursors in the human hair follicle mesenchyme
    • Ito, N., Sugawara, K., Bodó, E., Takigawa, M., van Beek, N., Ito, T., and Paus, R. (2010). Corticotropin-releasing hormone stimulates the in situ generation of mast cells from precursors in the human hair follicle mesenchyme. J. Invest. Dermatol. 130, 995-1004.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 995-1004
    • Ito, N.1    Sugawara, K.2    Bodó, E.3    Takigawa, M.4    van Beek, N.5    Ito, T.6    Paus, R.7
  • 48
    • 0017751779 scopus 로고
    • Thyrotropin-releasing hormone: abundance in the skin of the frog, Rana pipiens
    • Jackson, I.M., and Reichlin, S. (1977). Thyrotropin-releasing hormone: abundance in the skin of the frog, Rana pipiens. Science 198, 414-415.
    • (1977) Science , vol.198 , pp. 414-415
    • Jackson, I.M.1    Reichlin, S.2
  • 49
    • 77957934923 scopus 로고    scopus 로고
    • Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss
    • Kang, H., Wu, W.Y., Lo, B.K., Yu, M., Leung, G., Shapiro, J., and McElwee, K.J. (2010). Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss. J. Invest. Dermatol. 130, 2677-2680.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 2677-2680
    • Kang, H.1    Wu, W.Y.2    Lo, B.K.3    Yu, M.4    Leung, G.5    Shapiro, J.6    McElwee, K.J.7
  • 51
    • 12344274263 scopus 로고    scopus 로고
    • A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes
    • Kauser, S., Thody, A.J., Schallreuter, K.U., Gummer, C.L., and Tobin, D.J. (2005). A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes. Endocrinology 146, 532-543.
    • (2005) Endocrinology , vol.146 , pp. 532-543
    • Kauser, S.1    Thody, A.J.2    Schallreuter, K.U.3    Gummer, C.L.4    Tobin, D.J.5
  • 52
    • 33744454426 scopus 로고    scopus 로고
    • Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides
    • Kauser, S., Slominski, A., Wei, E.T., and Tobin, D.J. (2006). Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides. FASEB J. 20, 882-895.
    • (2006) FASEB J. , vol.20 , pp. 882-895
    • Kauser, S.1    Slominski, A.2    Wei, E.T.3    Tobin, D.J.4
  • 53
    • 77149156624 scopus 로고    scopus 로고
    • Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture
    • Kloepper, J.E., Sugawara, K., Al-Nuaimi, Y., Gáspár, E., van Beek, N., and Paus, R. (2010). Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture. Exp. Dermatol. 19, 305-312.
    • (2010) Exp. Dermatol. , vol.19 , pp. 305-312
    • Kloepper, J.E.1    Sugawara, K.2    Al-Nuaimi, Y.3    Gáspár, E.4    van Beek, N.5    Paus, R.6
  • 54
    • 26444588698 scopus 로고    scopus 로고
    • A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors
    • Kobayashi, H., Kromminga, A., Dunlop, T.W. et al. (2005). A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors. FASEB J. 19, 1710-1712.
    • (2005) FASEB J. , vol.19 , pp. 1710-1712
    • Kobayashi, H.1    Kromminga, A.2    Dunlop, T.W.3
  • 55
    • 67649648241 scopus 로고    scopus 로고
    • Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin
    • Kokot, A., Metze, D., Mouchet, N., Galibert, M.D., Schiller, M., Luger, T.A., and Böhm, M. (2009). Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin. Endocrinology 150, 3197-3206.
    • (2009) Endocrinology , vol.150 , pp. 3197-3206
    • Kokot, A.1    Metze, D.2    Mouchet, N.3    Galibert, M.D.4    Schiller, M.5    Luger, T.A.6    Böhm, M.7
  • 56
    • 77953306288 scopus 로고    scopus 로고
    • Williams Textbook of Endocrinology
    • (eds), 11th edn. (Philadelphia: Saunders).
    • Kronenberg, H.M., Melmed, S., Polonsky, K.S., and Larsen, P.R. (eds) (2008). Williams Textbook of Endocrinology, 11th edn. (Philadelphia: Saunders).
    • (2008)
    • Kronenberg, H.M.1    Melmed, S.2    Polonsky, K.S.3    Larsen, P.R.4
  • 57
    • 0031838353 scopus 로고    scopus 로고
    • Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
    • Krude, H., Biebermann, H., Luck, W., Horn, R., Brabant, G., and Grüters, A. (1998). Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nat. Genet. 19, 155-157.
    • (1998) Nat. Genet. , vol.19 , pp. 155-157
    • Krude, H.1    Biebermann, H.2    Luck, W.3    Horn, R.4    Brabant, G.5    Grüters, A.6
  • 59
    • 77951213264 scopus 로고    scopus 로고
    • Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro
    • Langan, E.A., Ramot, Y., Hanning, A., Poeggeler, B., Bíró, T., Gaspar, E., Funk, W., Griffiths, C.E., and Paus, R. (2010b). Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro. Br. J. Dermatol. 162, 1127-1131.
    • (2010) Br. J. Dermatol. , vol.162 , pp. 1127-1131
    • Langan, E.A.1    Ramot, Y.2    Hanning, A.3    Poeggeler, B.4    Bíró, T.5    Gaspar, E.6    Funk, W.7    Griffiths, C.E.8    Paus, R.9
  • 60
    • 77951189083 scopus 로고    scopus 로고
    • Human dermal stem cells differentiate into functional epidermal melanocytes
    • Li, L., Fukunaga-Kalabis, M., Yu, H., Xu, X., Kong, J., Lee, J.T., and Herlyn, M. (2010). Human dermal stem cells differentiate into functional epidermal melanocytes. J. Cell Sci. 123(Pt 6), 853-860.
    • (2010) J. Cell Sci. , vol.123 , Issue.PT 6 , pp. 853-860
    • Li, L.1    Fukunaga-Kalabis, M.2    Yu, H.3    Xu, X.4    Kong, J.5    Lee, J.T.6    Herlyn, M.7
  • 61
    • 33845425028 scopus 로고    scopus 로고
    • Towards the development of a simplified long-term organ culture method for human scalp skin and its appendages under serum-free conditions
    • Lu, Z., Hasse, S., Bodo, E., Rose, C., Funk, W., and Paus, R. (2007). Towards the development of a simplified long-term organ culture method for human scalp skin and its appendages under serum-free conditions. Exp. Dermatol. 16, 37-44.
    • (2007) Exp. Dermatol. , vol.16 , pp. 37-44
    • Lu, Z.1    Hasse, S.2    Bodo, E.3    Rose, C.4    Funk, W.5    Paus, R.6
  • 63
    • 0042674063 scopus 로고    scopus 로고
    • Mammalian skin evolution: a reevaluation
    • Maderson, P.F. (2003). Mammalian skin evolution: a reevaluation. Exp. Dermatol. 12, 233-236.
    • (2003) Exp. Dermatol. , vol.12 , pp. 233-236
    • Maderson, P.F.1
  • 64
    • 77956408835 scopus 로고    scopus 로고
    • KdPT, a tripeptide derivative of alpha-melanocyte-stimulating hormone, suppresses IL-1 beta-mediated cytokine expression and signaling in human sebocytes
    • Mastrofrancesco, A., Kokot, A., Eberle, A., Gibbons, N.C., Schallreuter, K.U., Strozyk, E., Picardo, M., Zouboulis, C.C., Luger, T.A., and Böhm, M. (2010). KdPT, a tripeptide derivative of alpha-melanocyte-stimulating hormone, suppresses IL-1 beta-mediated cytokine expression and signaling in human sebocytes. J. Immunol. 185, 1903-1911.
    • (2010) J. Immunol. , vol.185 , pp. 1903-1911
    • Mastrofrancesco, A.1    Kokot, A.2    Eberle, A.3    Gibbons, N.C.4    Schallreuter, K.U.5    Strozyk, E.6    Picardo, M.7    Zouboulis, C.C.8    Luger, T.A.9    Böhm, M.10
  • 65
    • 18244400239 scopus 로고    scopus 로고
    • Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model
    • McElwee, K.J., Freyschmidt-Paul, P., Hoffmann, R., Kissling, S., Hummel, S., Vitacolonna, M., and Zöller, M. (2005). Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model. J. Invest. Dermatol. 124, 947-957.
    • (2005) J. Invest. Dermatol. , vol.124 , pp. 947-957
    • McElwee, K.J.1    Freyschmidt-Paul, P.2    Hoffmann, R.3    Kissling, S.4    Hummel, S.5    Vitacolonna, M.6    Zöller, M.7
  • 68
    • 58349122081 scopus 로고    scopus 로고
    • The alpha-melanocyte stimulating hormone-related tripeptide K(D)PT stimulates human hair follicle pigmentation in situ under proinflammatory conditions
    • Meyer, K.C., Brzoska, T., Abels, C., and Paus, R. (2009a). The alpha-melanocyte stimulating hormone-related tripeptide K(D)PT stimulates human hair follicle pigmentation in situ under proinflammatory conditions. Br. J. Dermatol. 160, 433-437.
    • (2009) Br. J. Dermatol. , vol.160 , pp. 433-437
    • Meyer, K.C.1    Brzoska, T.2    Abels, C.3    Paus, R.4
  • 69
    • 72649105812 scopus 로고    scopus 로고
    • Immunomodulatory effects of the alpha-melanocyte-stimulating hormone-related tripeptide K(D)PT on human scalp hair follicles under proinflammatory conditions
    • Meyer, K.C., Bodó, E., Brzoska, T., Abels, C., and Paus, R. (2009b). Immunomodulatory effects of the alpha-melanocyte-stimulating hormone-related tripeptide K(D)PT on human scalp hair follicles under proinflammatory conditions. Br. J. Dermatol. 161, 1400-1403.
    • (2009) Br. J. Dermatol. , vol.161 , pp. 1400-1403
    • Meyer, K.C.1    Bodó, E.2    Brzoska, T.3    Abels, C.4    Paus, R.5
  • 70
    • 33748437539 scopus 로고    scopus 로고
    • Induction of cellular immunity against hair follicle melanocyte causes alopecia
    • Nagai, H., Oniki, S., Oka, M., Horikawa, T., and Nishigori, C. (2006). Induction of cellular immunity against hair follicle melanocyte causes alopecia. Arch. Dermatol. Res. 298, 131-134.
    • (2006) Arch. Dermatol. Res. , vol.298 , pp. 131-134
    • Nagai, H.1    Oniki, S.2    Oka, M.3    Horikawa, T.4    Nishigori, C.5
  • 73
    • 13244287677 scopus 로고    scopus 로고
    • Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche
    • Nishimura, E.K., Granter, S.R., and Fisher, D.E. (2005). Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. Science 307, 720-724.
    • (2005) Science , vol.307 , pp. 720-724
    • Nishimura, E.K.1    Granter, S.R.2    Fisher, D.E.3
  • 78
    • 72049090635 scopus 로고    scopus 로고
    • Exploring the "thyroid-skin connection": concepts, questions, and clinical relevance
    • Paus, R. (2010). Exploring the "thyroid-skin connection": concepts, questions, and clinical relevance. J. Invest. Dermatol. 130, 7-10.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 7-10
    • Paus, R.1
  • 79
    • 66149113193 scopus 로고    scopus 로고
    • Neuroendocrine perspectives in alopecia areata: does stress play a role?
    • Paus, R., and Arck, P. (2009). Neuroendocrine perspectives in alopecia areata: does stress play a role? J. Invest. Dermatol. 129, 1324-1326.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1324-1326
    • Paus, R.1    Arck, P.2
  • 80
    • 0027704964 scopus 로고
    • Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?
    • Paus, R., Slominski, A., and Czarnetzki, B.M. (1993). Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb? Yale J. Biol. Med. 66, 541-554.
    • (1993) Yale J. Biol. Med. , vol.66 , pp. 541-554
    • Paus, R.1    Slominski, A.2    Czarnetzki, B.M.3
  • 82
    • 30544439263 scopus 로고    scopus 로고
    • Neuroimmunoendocrine circuitry of the 'brain-skin connection'
    • Paus, R., Theoharides, T.C., and Arck, P.C. (2006). Neuroimmunoendocrine circuitry of the 'brain-skin connection'. Trends Immunol. 27, 32-39.
    • (2006) Trends Immunol. , vol.27 , pp. 32-39
    • Paus, R.1    Theoharides, T.C.2    Arck, P.C.3
  • 83
    • 44649158817 scopus 로고    scopus 로고
    • (Neuro-)endocrinology of epithelial hair follicle stem cells
    • Paus, R., Arck, P., and Tiede, S. (2008). (Neuro-)endocrinology of epithelial hair follicle stem cells. Mol. Cell. Endocrinol. 288, 38-51.
    • (2008) Mol. Cell. Endocrinol. , vol.288 , pp. 38-51
    • Paus, R.1    Arck, P.2    Tiede, S.3
  • 84
    • 0036295605 scopus 로고    scopus 로고
    • Migration of melanoblasts into the developing murine hair follicle is accompanied by transient c-Kit expression
    • Peters, E.M., Tobin, D.J., Botchkareva, N., Maurer, M., and Paus, R. (2002). Migration of melanoblasts into the developing murine hair follicle is accompanied by transient c-Kit expression. J. Histochem. Cytochem. 50, 751-766.
    • (2002) J. Histochem. Cytochem. , vol.50 , pp. 751-766
    • Peters, E.M.1    Tobin, D.J.2    Botchkareva, N.3    Maurer, M.4    Paus, R.5
  • 85
    • 33644878191 scopus 로고    scopus 로고
    • Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control
    • Peters, E.M., Arck, P.C., and Paus, R. (2006). Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control. Exp. Dermatol. 15, 1-13.
    • (2006) Exp. Dermatol. , vol.15 , pp. 1-13
    • Peters, E.M.1    Arck, P.C.2    Paus, R.3
  • 86
    • 38349078214 scopus 로고    scopus 로고
    • Probing the effects of stress mediators on the human hair follicle: substance P holds central position
    • Peters, E.M., Liotiri, S., Bodó, E., Hagen, E., Bíró, T., Arck, P.C., and Paus, R. (2007). Probing the effects of stress mediators on the human hair follicle: substance P holds central position. Am. J. Pathol. 171, 1872-1886.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1872-1886
    • Peters, E.M.1    Liotiri, S.2    Bodó, E.3    Hagen, E.4    Bíró, T.5    Arck, P.C.6    Paus, R.7
  • 87
    • 77954223152 scopus 로고    scopus 로고
    • Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
    • Petukhova, L., Duvic, M., Hordinsky, M. et al. (2010). Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature 466, 113-117.
    • (2010) Nature , vol.466 , pp. 113-117
    • Petukhova, L.1    Duvic, M.2    Hordinsky, M.3
  • 88
    • 0025115553 scopus 로고
    • Human hair growth in vitro
    • Philpott, M.P., Green, M.R., and Kealey, T. (1990). Human hair growth in vitro. J. Cell Sci. 97(Pt 3), 463-471.
    • (1990) J. Cell Sci. , vol.97 , Issue.PT 3 , pp. 463-471
    • Philpott, M.P.1    Green, M.R.2    Kealey, T.3
  • 89
    • 69149101414 scopus 로고    scopus 로고
    • What are melanocytes really doing all day long...?
    • Plonka, P.M., Passeron, T., Brenner, M. et al. (2009). What are melanocytes really doing all day long...? Exp. Dermatol. 18, 799-819.
    • (2009) Exp. Dermatol. , vol.18 , pp. 799-819
    • Plonka, P.M.1    Passeron, T.2    Brenner, M.3
  • 90
    • 77954847858 scopus 로고    scopus 로고
    • A simple assay for the study of human hair follicle damage induced by ionizing irradiation
    • Poeggeler, B., Bodó, E., Nadrowitz, R., Dunst, J., and Paus, R. (2010). A simple assay for the study of human hair follicle damage induced by ionizing irradiation. Exp. Dermatol. 19, e306-e309.
    • (2010) Exp. Dermatol. , vol.19
    • Poeggeler, B.1    Bodó, E.2    Nadrowitz, R.3    Dunst, J.4    Paus, R.5
  • 92
    • 77953489794 scopus 로고    scopus 로고
    • Prolactin - a novel neuroendocrine regulator of human keratin expression in situ
    • Ramot, Y., Bíró, T., Tiede, S. et al. (2010). Prolactin - a novel neuroendocrine regulator of human keratin expression in situ. FASEB J. 24, 1768-1779.
    • (2010) FASEB J. , vol.24 , pp. 1768-1779
    • Ramot, Y.1    Bíró, T.2    Tiede, S.3
  • 93
    • 0346786217 scopus 로고    scopus 로고
    • Genetics of hair and skin color
    • Rees, J. (2003). Genetics of hair and skin color. Annu. Rev. Genet. 37, 67-90.
    • (2003) Annu. Rev. Genet. , vol.37 , pp. 67-90
    • Rees, J.1
  • 95
    • 34249822507 scopus 로고    scopus 로고
    • Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis
    • Rousseau, K., Kauser, S., Pritchard, L.E., Warhurst, A., Oliver, R.L., Slominski, A., Wei, E.T., Thody, A.J., Tobin, D.J., and White, A. (2007). Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis. FASEB J. 21, 1844-1856.
    • (2007) FASEB J. , vol.21 , pp. 1844-1856
    • Rousseau, K.1    Kauser, S.2    Pritchard, L.E.3    Warhurst, A.4    Oliver, R.L.5    Slominski, A.6    Wei, E.T.7    Thody, A.J.8    Tobin, D.J.9    White, A.10
  • 96
    • 77953567567 scopus 로고    scopus 로고
    • The untranslated side of hair and skin mammalian pigmentation: beyond coding sequences
    • Rouzaud, F., Oulmouden, A., and Kos, L. (2010). The untranslated side of hair and skin mammalian pigmentation: beyond coding sequences. IUBMB Life 62, 340-346.
    • (2010) IUBMB Life , vol.62 , pp. 340-346
    • Rouzaud, F.1    Oulmouden, A.2    Kos, L.3
  • 99
    • 41949092429 scopus 로고    scopus 로고
    • Regulation of melanogenesis - controversies and new concepts
    • Schallreuter, K.U., Kothari, S., Chavan, B., and Spencer, J.D. (2008a). Regulation of melanogenesis - controversies and new concepts. Exp. Dermatol. 17, 395-404.
    • (2008) Exp. Dermatol. , vol.17 , pp. 395-404
    • Schallreuter, K.U.1    Kothari, S.2    Chavan, B.3    Spencer, J.D.4
  • 100
    • 38349054169 scopus 로고    scopus 로고
    • Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?
    • Schallreuter, K.U., Bahadoran, P., Picardo, M. et al. (2008b). Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else? Exp. Dermatol. 17, 139-160.
    • (2008) Exp. Dermatol. , vol.17 , pp. 139-160
    • Schallreuter, K.U.1    Bahadoran, P.2    Picardo, M.3
  • 101
    • 78651449753 scopus 로고    scopus 로고
    • The redox - biochemistry of human hair pigmentation
    • doi: 10.1111/j.1755-148X.2010.00794.x.
    • Schallreuter, K.U., Salem, M.M., Hasse, S., and Rokos, H. (2010). The redox - biochemistry of human hair pigmentation. Pigment Cell Melanoma Res. doi: 10.1111/j.1755-148X.2010.00794.x.
    • (2010) Pigment Cell Melanoma Res
    • Schallreuter, K.U.1    Salem, M.M.2    Hasse, S.3    Rokos, H.4
  • 102
    • 0344117854 scopus 로고    scopus 로고
    • Thyrotropin releasing hormone (TRH) selectively binds and activates the melanocortin 1 receptor
    • Schiöth, H.B., Prusis, P., Muceniece, R., Mutulis, F., Mutule, I., and Wikberg, J.E. (1999). Thyrotropin releasing hormone (TRH) selectively binds and activates the melanocortin 1 receptor. Peptides 20, 395-400.
    • (1999) Peptides , vol.20 , pp. 395-400
    • Schiöth, H.B.1    Prusis, P.2    Muceniece, R.3    Mutulis, F.4    Mutule, I.5    Wikberg, J.E.6
  • 105
    • 69149092876 scopus 로고    scopus 로고
    • Neuroendocrine activity of the melanocyte
    • Slominski, A. (2009). Neuroendocrine activity of the melanocyte. Exp. Dermatol. 18, 760-763.
    • (2009) Exp. Dermatol. , vol.18 , pp. 760-763
    • Slominski, A.1
  • 106
    • 0027181947 scopus 로고
    • Melanogenesi is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth
    • Slominski, A., and Paus, R. (1993). Melanogenesi is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth. J. Invest. Dermatol. 101, 90S-97S.
    • (1993) J. Invest. Dermatol. , vol.101
    • Slominski, A.1    Paus, R.2
  • 107
    • 0033694888 scopus 로고    scopus 로고
    • Neuroendocrinology of the skin
    • Slominski, A., and Wortsman, J. (2000). Neuroendocrinology of the skin. Endocr. Rev. 21, 457-487.
    • (2000) Endocr. Rev. , vol.21 , pp. 457-487
    • Slominski, A.1    Wortsman, J.2
  • 108
    • 0026541440 scopus 로고
    • Proopiomelanocortin expression in the skin during induced hair growth in mice
    • Slominski, A., Paus, R., and Mazurkiewicz, J. (1992). Proopiomelanocortin expression in the skin during induced hair growth in mice. Experientia 48, 50-54.
    • (1992) Experientia , vol.48 , pp. 50-54
    • Slominski, A.1    Paus, R.2    Mazurkiewicz, J.3
  • 109
    • 0027361601 scopus 로고
    • Melanocytes as "sensory" and regulatory cells in the epidermis
    • Slominski, A., Paus, R., and Schadendorf, D. (1993a). Melanocytes as "sensory" and regulatory cells in the epidermis. J. Theor. Biol. 164, 103-120.
    • (1993) J. Theor. Biol. , vol.164 , pp. 103-120
    • Slominski, A.1    Paus, R.2    Schadendorf, D.3
  • 115
    • 0032763672 scopus 로고    scopus 로고
    • Cutaneous expression of CRH and CRH-R. Is there a "skin stress response system?"
    • Slominski, A.T., Botchkarev, V., Choudhry, M. et al. (1999b). Cutaneous expression of CRH and CRH-R. Is there a "skin stress response system?". Ann. N. Y. Acad. Sci. 885, 287-311.
    • (1999) Ann. N. Y. Acad. Sci. , vol.885 , pp. 287-311
    • Slominski, A.T.1    Botchkarev, V.2    Choudhry, M.3
  • 116
    • 0033946195 scopus 로고    scopus 로고
    • Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress
    • Slominski, A., Wortsman, J., Luger, T., Paus, R., and Solomon, S. (2000). Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress. Physiol. Rev. 80, 979-1020.
    • (2000) Physiol. Rev. , vol.80 , pp. 979-1020
    • Slominski, A.1    Wortsman, J.2    Luger, T.3    Paus, R.4    Solomon, S.5
  • 117
    • 0036917233 scopus 로고    scopus 로고
    • Expression of hypothalamic-pituitary-thyroid axis related genes in the human skin
    • Slominski, A., Wortsman, J., Kohn, L. et al. (2002). Expression of hypothalamic-pituitary-thyroid axis related genes in the human skin. J. Invest. Dermatol. 119, 1449-1455.
    • (2002) J. Invest. Dermatol. , vol.119 , pp. 1449-1455
    • Slominski, A.1    Wortsman, J.2    Kohn, L.3
  • 118
    • 4644237315 scopus 로고    scopus 로고
    • Melanin pigmentation in mammalian skin and its hormonal regulation
    • Slominski, A., Tobin, D.J., Shibahara, S., and Wortsman, J. (2004). Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol. Rev. 84, 1155-1228.
    • (2004) Physiol. Rev. , vol.84 , pp. 1155-1228
    • Slominski, A.1    Tobin, D.J.2    Shibahara, S.3    Wortsman, J.4
  • 119
    • 13244267262 scopus 로고    scopus 로고
    • The cutaneous serotoninergic/melatoninergic system: securing a place under the sun
    • Slominski, A., Wortsman, J., and Tobin, D.J. (2005a). The cutaneous serotoninergic/melatoninergic system: securing a place under the sun. FASEB J. 19, 176-194.
    • (2005) FASEB J. , vol.19 , pp. 176-194
    • Slominski, A.1    Wortsman, J.2    Tobin, D.J.3
  • 121
  • 123
    • 70350102180 scopus 로고    scopus 로고
    • alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes
    • Song, X., Mosby, N., Yang, J., Xu, A., Abdel-Malek, Z., and Kadekaro, A.L. (2009). alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes. Pigment Cell Melanoma Res. 22, 809-818.
    • (2009) Pigment Cell Melanoma Res. , vol.22 , pp. 809-818
    • Song, X.1    Mosby, N.2    Yang, J.3    Xu, A.4    Abdel-Malek, Z.5    Kadekaro, A.L.6
  • 124
    • 70349750288 scopus 로고    scopus 로고
    • Lentiviral vector-mediated gene transfer to human hair follicles
    • Sriwiriyanont, P., Hachiya, A., Pickens, W.L. et al. (2009). Lentiviral vector-mediated gene transfer to human hair follicles. J. Invest. Dermatol. 129, 2296-2299.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 2296-2299
    • Sriwiriyanont, P.1    Hachiya, A.2    Pickens, W.L.3
  • 125
    • 0035134022 scopus 로고    scopus 로고
    • Controls of hair follicle cycling
    • Stenn, K.S., and Paus, R. (2001). Controls of hair follicle cycling. Physiol. Rev. 81, 449-494.
    • (2001) Physiol. Rev. , vol.81 , pp. 449-494
    • Stenn, K.S.1    Paus, R.2
  • 126
    • 63149157274 scopus 로고    scopus 로고
    • Molecular genetics of human pigmentation diversity
    • Sturm, R.A. (2009). Molecular genetics of human pigmentation diversity. Hum. Mol. Genet. 18(R1), R9-R17.
    • (2009) Hum. Mol. Genet. , vol.18 , Issue.R1
    • Sturm, R.A.1
  • 127
    • 70350048941 scopus 로고    scopus 로고
    • Nestin in human skin: exclusive expression in intramesenchymal skin compartments and regulation by leptin
    • Tiede, S., Kloepper, J.E., Ernst, N., Poeggeler, B., Kruse, C., and Paus, R. (2009a). Nestin in human skin: exclusive expression in intramesenchymal skin compartments and regulation by leptin. J. Invest. Dermatol. 129, 2711-2720.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 2711-2720
    • Tiede, S.1    Kloepper, J.E.2    Ernst, N.3    Poeggeler, B.4    Kruse, C.5    Paus, R.6
  • 128
    • 72849144525 scopus 로고    scopus 로고
    • Nonviral in situ green fluorescent protein labeling and culture of primary, adult human hair follicle epithelial progenitor cells
    • Tiede, S., Koop, N., Kloepper, J.E., Fässler, R., and Paus, R. (2009b). Nonviral in situ green fluorescent protein labeling and culture of primary, adult human hair follicle epithelial progenitor cells. Stem Cells 27, 2793-2803.
    • (2009) Stem Cells , vol.27 , pp. 2793-2803
    • Tiede, S.1    Koop, N.2    Kloepper, J.E.3    Fässler, R.4    Paus, R.5
  • 129
    • 77955927951 scopus 로고    scopus 로고
    • Endocrine controls of primary adult human stem cell biology: thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro
    • Tiede, S., Bohm, K., Meier, N., Funk, W., and Paus, R. (2010). Endocrine controls of primary adult human stem cell biology: thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro. Eur. J. Cell Biol. 89, 769-777.
    • (2010) Eur. J. Cell Biol. , vol.89 , pp. 769-777
    • Tiede, S.1    Bohm, K.2    Meier, N.3    Funk, W.4    Paus, R.5
  • 131
    • 84885159879 scopus 로고    scopus 로고
    • Aging Hair
    • In, R. Trüeb, and D. Tobin, eds. (Heidelberg: Springer)
    • Tobin, D. (2010b). The aging hair pigmentary unit, Chap. 9. In Aging Hair, R. Trüeb, and D. Tobin, eds. (Heidelberg: Springer), pp. 77-90.
    • (2010) The aging hair pigmentary unit, Chap. 9 , pp. 77-90
    • Tobin, D.1
  • 132
    • 78651424037 scopus 로고    scopus 로고
    • Ex vivo organ culture of human hair follicles: a model epithelial-neuroectodermal-mesenchymal interaction system
    • Tobin, D.J. (2011). Ex vivo organ culture of human hair follicles: a model epithelial-neuroectodermal-mesenchymal interaction system. Methods Mol. Biol. 695, 213-227.
    • (2011) Methods Mol. Biol. , vol.695 , pp. 213-227
    • Tobin, D.J.1
  • 133
    • 27644527920 scopus 로고    scopus 로고
    • Hair melanocytes as neuro-endocrine sensors - pigments for our imagination
    • Tobin, D.J., and Kauser, S. (2005). Hair melanocytes as neuro-endocrine sensors - pigments for our imagination. Mol. Cell. Endocrinol. 243, 1-11.
    • (2005) Mol. Cell. Endocrinol. , vol.243 , pp. 1-11
    • Tobin, D.J.1    Kauser, S.2
  • 134
    • 0035192846 scopus 로고    scopus 로고
    • Graying: gerontobiology of the hair follicle pigmentary unit
    • Erratum in: Exp Gerontol 2001 36(3):591-592
    • Tobin, D.J., and Paus, R. (2001). Graying: gerontobiology of the hair follicle pigmentary unit. Exp. Gerontol. 36, 29-54. Erratum in: Exp Gerontol 2001 36(3):591-592
    • (2001) Exp. Gerontol. , vol.36 , pp. 29-54
    • Tobin, D.J.1    Paus, R.2
  • 135
    • 0032456749 scopus 로고    scopus 로고
    • Do hair bulb melanocytes undergo apoptosis during hair follicle regression (catagen)?
    • Tobin, D.J., Hagen, E., Botchkarev, V.A., and Paus, R. (1998). Do hair bulb melanocytes undergo apoptosis during hair follicle regression (catagen)? J. Invest. Dermatol. 111, 941-947.
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 941-947
    • Tobin, D.J.1    Hagen, E.2    Botchkarev, V.A.3    Paus, R.4
  • 138
    • 33847794965 scopus 로고    scopus 로고
    • Antisense oligonucleotide targeting fibroblast growth factor receptor (FGFR)-1 stimulates cellular activity of hair follicles in an in vitro organ culture system
    • Tsuboi, R., Yamazaki, M., Matsuda, Y., Uchida, K., Ueki, R., and Ogawa, H. (2007). Antisense oligonucleotide targeting fibroblast growth factor receptor (FGFR)-1 stimulates cellular activity of hair follicles in an in vitro organ culture system. Int. J. Dermatol. 46, 259-263.
    • (2007) Int. J. Dermatol. , vol.46 , pp. 259-263
    • Tsuboi, R.1    Yamazaki, M.2    Matsuda, Y.3    Uchida, K.4    Ueki, R.5    Ogawa, H.6
  • 139
    • 77954649705 scopus 로고    scopus 로고
    • "Transcription physiology" of pigment formation in melanocytes: central role of MITF
    • Vachtenheim, J., and Borovanskỳ, J. (2010). "Transcription physiology" of pigment formation in melanocytes: central role of MITF. Exp. Dermatol. 19, 617-627.
    • (2010) Exp. Dermatol. , vol.19 , pp. 617-627
    • Vachtenheim, J.1    Borovanskỳ, J.2
  • 140
    • 67651113737 scopus 로고    scopus 로고
    • Repigmentation by outer-root-sheath-derived melanocytes: proof of concept in vitiligo and leucoderma
    • Vanscheidt, W., and Hunziker, T. (2009). Repigmentation by outer-root-sheath-derived melanocytes: proof of concept in vitiligo and leucoderma. Dermatology 218, 342-343.
    • (2009) Dermatology , vol.218 , pp. 342-343
    • Vanscheidt, W.1    Hunziker, T.2
  • 141
    • 33748756028 scopus 로고    scopus 로고
    • TGF-beta: a mobile purveyor of immune privilege
    • Wahl, S.M., Wen, J., and Moutsopoulos, N. (2006). TGF-beta: a mobile purveyor of immune privilege. Immunol. Rev. 213, 213-227.
    • (2006) Immunol. Rev. , vol.213 , pp. 213-227
    • Wahl, S.M.1    Wen, J.2    Moutsopoulos, N.3
  • 142
    • 78651425691 scopus 로고    scopus 로고
    • The Pigmentary System
    • In, J.J. Nordlund, eds. 2nd edn. (Malden, MA: Blackwell Publishing)
    • Westerhof, W., Njoo, D., and Menke, H.E. (2006). Sudden Whitening of Hair. In The Pigmentary System, J.J. Nordlund, et al., eds. 2nd edn. (Malden, MA: Blackwell Publishing), pp. 764-66.
    • (2006) Sudden Whitening of Hair , pp. 764-66
    • Westerhof, W.1    Njoo, D.2    Menke, H.E.3
  • 143
    • 44949133102 scopus 로고    scopus 로고
    • A plaidoyer for cutaneous enzymology: our view of some important unanswered questions on the contributions of selected key enzymes to epidermal homeostasis
    • Wood, J.M., and Schallreuter, K.U. (2008). A plaidoyer for cutaneous enzymology: our view of some important unanswered questions on the contributions of selected key enzymes to epidermal homeostasis. Exp. Dermatol. 17, 569-578.
    • (2008) Exp. Dermatol. , vol.17 , pp. 569-578
    • Wood, J.M.1    Schallreuter, K.U.2
  • 145
    • 68549135300 scopus 로고    scopus 로고
    • Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair
    • Wood, J.M., Decker, H., Hartmann, H. et al. (2009). Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J. 23, 2065-2075.
    • (2009) FASEB J. , vol.23 , pp. 2065-2075
    • Wood, J.M.1    Decker, H.2    Hartmann, H.3
  • 146
    • 67649216556 scopus 로고    scopus 로고
    • Physiological factors that regulate skin pigmentation
    • Yamaguchi, Y., and Hearing, V.J. (2009). Physiological factors that regulate skin pigmentation. Biofactors 35, 193-199.
    • (2009) Biofactors , vol.35 , pp. 193-199
    • Yamaguchi, Y.1    Hearing, V.J.2
  • 147
    • 38149138738 scopus 로고    scopus 로고
    • In vitro expansion of immature melanoblasts and their ability to repopulate melanocyte stem cells in the hair follicle
    • Yonetani, S., Moriyama, M., Nishigori, C., Osawa, M., and Nishikawa, S. (2008). In vitro expansion of immature melanoblasts and their ability to repopulate melanocyte stem cells in the hair follicle. J. Invest. Dermatol. 128, 408-420.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 408-420
    • Yonetani, S.1    Moriyama, M.2    Nishigori, C.3    Osawa, M.4    Nishikawa, S.5
  • 148
    • 0028167284 scopus 로고
    • Alopecia à deux: simultaneous occurrence of alopecia in a husband and wife
    • Zalka, A.D., Byarlay, J.A., and Goldsmith, L.A. (1994). Alopecia à deux: simultaneous occurrence of alopecia in a husband and wife. Arch. Dermatol. 130, 390-392.
    • (1994) Arch. Dermatol. , vol.130 , pp. 390-392
    • Zalka, A.D.1    Byarlay, J.A.2    Goldsmith, L.A.3
  • 149
    • 66149140289 scopus 로고    scopus 로고
    • Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model
    • Zhang, X., Yu, M., Yu, W., Weinberg, J., Shapiro, J., and McElwee, K.J. (2009). Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model. J. Invest. Dermatol. 129, 1527-1538.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1527-1538
    • Zhang, X.1    Yu, M.2    Yu, W.3    Weinberg, J.4    Shapiro, J.5    McElwee, K.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.