α-MSH can control the essential cofactor 6-tetrahydrobiopterin in melanogenesis

Annals of the New York Academy of Sciences

Volumn 885, Issue , 1999, Pages 329-341

  Schallreuter, Karin U ^a   Moore, Jeremy ^a   Tobin, Desmond J ^a   Gibbons, Nicholas J P ^a   Marshall, Harriet S ^a   Jenner, Tracey ^a   Beazley, Wayne D ^a   Wood, John M ^a  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; MONOPHENOL MONOOXYGENASE; NITRIC OXIDE; PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; TETRAHYDROBIOPTERIN; TRYPTOPHAN; TYROSINE;

AMINO ACID METABOLISM; CONFERENCE PAPER; EPIDERMIS; HUMAN; HYDROXYLATION; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; KERATINOCYTE; MELANOCYTE; MELANOGENESIS; PROTEIN DOMAIN;

EID: 0032778493     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb08688.x     Document Type: Conference Paper

References (30)

1. 1. Prota, G. 1976. Melanins and Melanogenesis. Academic Press, New York.
2. 2. Fitzpatrick, T.B. et al. 1971. Photomedicine. In Dermatology in General Medicine. McGraw-Hill Book Co, New York.
3. 3. Frenk, E. & J.P. Scheelhorn. 1969. Morphology of the epidermal melanin unit. Dermatologica 139: 271-277.
4. 4. Iwata, M. et al. 1990. The relationship between tyrosinase activity and skin colour in human foreskins. J. Invest. Dermatol. 95: 9-15.
5. 5. Iozumi, K. et al. 1993. Role of tyrosinase as the determinant of pigmentation in cultured human melanocytes. J. Invest. Dermatol. 100: 806-811.
6. 6. Kaufman, S. 1964. The role of pteridines in the enzymatic conversion of phenylalanine to tyrosine. Trans. N.Y. Acad. Sci. 26: 977-983.
7. 7. Schallreuter, K.U. et al. 1994. Regulation of melanin biosynthesis in the human epidermis by tetrahydrobiopterin. Science. 263: 1444-1446.
8. 8. Schallreuter, K.U. et al. 1994. Defective tetrahydrobiopterin and catecholamine biosynthesis in the depigmentation disorder vitiligo. Biochim. Biophys. Acta 1226: 181-192.
9. 9. Schallreuter, K.U. et al. 1997. Pteridines in the control of pigmentation. J. Invest. Dermatol. 109: 31-35.
10. 10. Wood, J.M. et al. 1995. A specific tetrahydrobiopterin binding domain on tyrosinase controls melanogenesis. Biochem. Biophys. Res. Commun. 206: 480-485.
11. 11. Schallreuter, K.U. et al. 1998. 6-tetrahydrobiopterin functions as a UVB-light switch for de novo melanogenesis. Biochem. Biophys. Acta 1382: 339-344.
12. 2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. J. Invest. Dermatol. Symp. Proc. In press.
13. 13. Lerner, A.B. & J.S. McGuire. 1961. Effect of alpha and beta melanocyte stimulating hormones on skin color of man. Nature 189: 176-179.
14. 14. Lerner, A.B. 1993. The discovery of the melanotropins. Ann. N.Y. Acad. Sci. 680: 2-12.
15. 15. Wintzen, M. et al. 1996. Proopiomelanocortin, its derived peptides in the skin. J. Invest. Dermatol. 106: 3-10.
16. 16. Rungta, D. et al. 1996. Regulation of tyrosinase mRNA in mouse melanoma cells by α-melanocyte-stimulating hormone. J. Invest. Dermatol. 107: 689-693.
17. 17. Pawelek, J. et al. 1973. Molecular biology of pigment cells. Molecular controls in mammalian pigmentation. Yale. J. Biol. Med. 46: 430-443.
18. 18. Fuller, B.B. et al. 1987. Alpha-melanocyte stimulating hormone regulation of tyrosinase in Cloudman S-91 mouse melanoma cell cultures. J. Biol. Chem. 262: 4024-4033.
19. 19. Stryer, L. 1988. Biochemistry, 3rd ed. 993-994. W.H. Freeman. New York.
20. 20. Wakamatsu, K. et al. 1997. Characterisation of ACTH peptides in human skin and their activation of the melanocortin-1 receptor. Pigment. Cell. Res. 10: 288-297.
21. 21. Schallreuter, K.U. et al. 1998. Perturbed epidermal pterin metabolism in Hermansky-Pudlak syndrome. J. Invest. Dermatol. 111:511-516.
22. 22. Davis, M.D. et al. 1996. Structure-function relationships of phenylalanine hydroxy-lase revealed by radiation target analysis. Arch. Biochem. Biophys. 325: 235-241.
23. 23. Schallreuter, K.U. et al. 1997. Pterins and α-MSH in the control of pigmentation in the human epidermis. In Chemistry and Biology of Pteridines and Folates. W. Pfleiderer & H. Rokos, Eds.: 791-795. Blackwell Science, Berlin.
24. 24. Moore, J. et al. 1997. Studies in the structure of the tetrahydrobiopterin/α-MSH complex formation using Fourier-Transform Raman spectroscopy. In Chemistry and Biology of Pteridines and Folates. W. Pfleiderer & H. Rokos, Eds.: 831-835. Blackwell Science, Berlin.
25. -1 in the Raman spectra of tyrosyl residues in proteins and certain model compounds. Biochem. 4: 4870-4876.
26. 26. Chakraborty, A.K. et al. 1996. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B. Biochim. Biophys. Acta 1313: 130-138.
27. 27. Werner, E.R. et al. 1990. Impact of tumour necrosis factor-α and interferon-γ on tetrahydrobiopterin synthesis in murine fibroblasts and macrophages. Biochem. J. 280: 709-714.
28. 28. Ziegler, I. et al. 1990. Control of tetrahydrobiopterin synthesis in T-lymphocytes by synergistic action of interferon-γ and interleukin-2. J. Biol. Chem. 265: 17026-17030.
29. 29. Schallreuter, K.U. et al. 1998. Pterins in human hair follicle cells and the synchronized murine hair cycle. J. Invest. Dermatol. 111: 545-550.
30. 30. Pittelkow, M.R. & Shipley, G.D. 1989. Serum free culture of normal human melanocytes: growth kinetics and growth factor requirements. J. Cell. Physiol. 140: 565-576.