Do hair bulb melanocytes undergo apotosis during hair follicle regression (catagen)?

Journal of Investigative Dermatology

Volumn 111, Issue 6, 1998, Pages 941-947

  Tobin, Desmond J ^a   Hagen, Evelin ^b   Botchkarev, Vladimir A ^b   Paus, Ralf ^b  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Cell death; Cyclophosphamide; Dexamethasone; Differentiation; Electron microscopy; Melanosomes

Indexed keywords

CELL PROTEIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; MELANIN; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; HAIR FOLLICLE; HAIR GROWTH; HAIR LOSS; HAIR ROOT; KERATINOCYTE; MELANOCYTE; MELANOGENESIS; MELANOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

EID: 0032456749     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00417.x     Document Type: Article

References (48)

1. Arroyo Garcia L, Covelli C, Escobar C, Carrascal E, Falabella R: Melanocyte reservoir in vitiligo. Int J Dermatol 33:484-487, 1994
2. Bulfone-Paus S, Ungureanu D, Pohl T, et al: Interleukin-15 protects from lethal apoptosis in vivo. Nature Medicine 3:1124-1128, 1997
3. Cesarini JP. Hair melanin and hair color. In: Orfanos CE, Happle R (eds). Hair, Hair Diseases. Berlin: Springer-Verlag, 1990, pp. 165-197
4. Chase HB: Growth of the hair. Physiol Rev 34:113-126, 1954
5. Cui J, Shen Wang G: Role of hair follicle in the repigmentation of vitiligo. J Invest Dermatol 97:410-416, 1991
6. Dawber R (ed.). Diseases of the hair and scalp. Oxford: Blackwell Scientific Publications, 1997
7. Fitzpatrick TB, Quevedo WC, Szabo G, Seiji M: Biology of the melanin pigmentary system. In: Fitzpatrick TB, et al (eds). Dermatology in General Practice. New York: McGraw-Hill, 1971, pp. 117-146
8. Horikawa T, Norris DA, Johnson TW, et al: Dopa-negative melanocytes in the ORS of human hair follicle express pre- melanosomal antigens but not melanosomal antigens or the melanosome-associated glycoprotein tyrosinase, TRP-1, and TRP-2. J Invest Dermatol 106:28-35, 1996
9. Jimenéz M, Kameyama K, Maloy WL, Tomita Y, Hearing VJ: Mammalian tyrosinase: biosynthesis, processing and modulation by melanocytes stimulating hormone. Proc Natl Acad Sci USA 85:3830-3834, 1988
10. Jimenéz M, Maloy WL, Hearing VJ: Specific identification of an authentic tyrosinase clone. J Biol Chem 264:3397-3403, 1989
11. Karnovsky MJ: Fonnaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy. J Cell Biol 27:137-138, 1965
12. Lindner G, Borchkarev VA, Botchkareva NV, Ling G, van der Veen C, Paus R: Analysis of apoptosis during hair follicle regression (catagen). Am J Pathol 151:1601-1617, 1997
13. Montagni W, Chase HB: Histology and cytochemistry of human skin. X-irradiation of the scalp. Am J Anat 99:425-446, 1956
14. Nagl W: Different growth rates of pigmented and white hair in the beard: differentiation vs. proliferation? Br J Dermatol 132:94-97, 1995
15. Ortonne JP, Prota G: Hair melanins and hair color: Ultrastructural and biochemical aspects. J Invest Dermatol 101:82S-89S, 1993
16. Parakkal PF: Transfer of premelanosomes into keratinizing cells of albino hair follicle. J Cell Biol 35:473-477, 1967
17. Paus R: Control of the hair cycle and hair diseases as cycling disorders. Curr Opinion Dermatol 3:248-258, 1996
18. Paus R, Stenn KS, Link RE: Telogen skin contains an inhibitor of hair growth. Br J Dermatol 122:777-784, 1990
19. Paus R, Handjiski B, Eichmüller S, Czarnetzki BM: Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by DEX. Am J Pathol 144:719-734, 1994a
20. Paus R, Handijiski B, Czarnetzki BM, Eichmüller S: A murine model for inducing and manipulating hair follicle regression (catagen). Effects of dexamethasone and cyclosporin A. J Invest Dermatol 103:143-147, 1994b
21. Paus R, Schilli MB, Handjiski B, Menrad A, Henz BM, Plonka P: Topical calcitriol enhances normal hair regrowth but does not prevent chemotherapy-induced alopecia in mice. Cancer Res 56:4438-4443, 1996
22. Paus R, Foitzik K, Welker P, Bulfone-Paus S, Eichmüller S: Transforming growth factor-β receptor type I and type II expression during murine hair follicle development and cycling. J Invest Dermatol 109:518-526, 1997
23. Philpott MP, Sanders DA, Kealey T: Effects of insulin and insulin-like growth factors on cultured human hair follicles - IGF-1 at physiological concentrations is an important regulator of hair follicle growth in vitro. J Invest Dermatol 102:857-861, 1994
24. Potten CS. The x irradiation of melanocyte precursor cell in resting hair follicle. In: Riley V (ed.). Pigmentation: its genesis and biologic control. New York: Appelton Century Crofts, 1972, pp. 433-440
25. Prunerias M: Interaction between keratinocytes and dendritic cells. J Invest Dermatol 52:1-17, 1969
26. Rosenquist TA, Martin GR: Fibroblast growth factor signaling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle. Dev Dynamics 205:379-386, 1996
27. Schilli MB, Ray S, Paus R, Obitabot E, Hollick MF: Control of hair growth with parathyroid hormone (7-34). J Invest Dermatol 108:928-932, 1997
28. Searle J, Kerr JF, Bishop CJ: Necrosis and apoptosis: distinct modes of cell death with fundamentally different significance. Pathol Ann 17:229-259, 1982
29. Seiberg M, Marthinuss J, Stenn KS: Changes in expression of apoptosis-associated genes in skin mark early catagen. J Invets Dermatol 104:78-82, 1995
30. Slominski A, Paus R: Melanogenesis is coupled to murine anagen: Towards new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth. J Invest Dermatol 101:905-975, 1993
31. Slominski A, Paus R, Constantino R: Differential expression and activity of melanogenesis-related proteins during induced hair growth in mice. J Invest Dermatol 96:172-179, 1991
32. Slominski A, Paus R, Schadendorf D: Melanocytes as "sensory" and regulatory cells in the epidermis. J Theor Biol 164:103-120, 1993
33. Slominski A, Paus R, Plonka P, Chakraborty A, Maurer M, Pruski D, Lukiewicz S: Melanogenesis during the anagen-catagen-telogen transformation of the murine hair cycle. J Invest Dermatol 102:862-869, 1994
34. Slominski A, Paus R, Plonka P, Handijiski B, Maurer M, Chakraborry A, Mihm MC: Pharmacological disruption of hair follicle pigmentation by CYP as a model for studying the melanocyte response to and recovery from cytotoxic damage in situ. J Invets Dermatol 106:1203-1211, 1996
35. Starrico GJR: Mechanism of migration of the melanocytes from the hair follicle into the epidermis following dermabrasion. J Invest Dermatol 36:99-104, 1961
36. Straile WE, Chase HB, Arsenault C: Growth and differentiation of the hair follicle between periods of activity and quiescence. J Exp Zool 148:205-216, 1961
37. Sugiyama S: Mode of re-differentiation and melanogenesis of melanocytes in murine hair follicle. J Ultrastruct Res 67:40-54, 1979
38. Sugiyama S, Kukita A. Melanocyte reservoir in the hair follicle during the hair growth cycle: An electron microscope study. In: Toda K, Ishibashi Y, Hori Y, Morikawa F (eds). Biology and Disease of Hair. Tokyo: University of Tokyo Press, 1976, pp. 181-200
39. Sweet SE, Quevedo WC: Role of melanocyte morphology in pigmentation of murine hair. Anat Rec 160:243-254, 1968
40. Tobin DJ: A possible role for Langerhans cells in the removal of melanin from early catagen hair follicles. Br J Dermatol 138:795-798, 1998
41. Tobin DJ, Bystryn J-C: Different populations of melanocytes are present in human hair follicle and epidermis. Pigment Cell Res 9:304-310, 1996
42. Tobin DJ, Fenton DA, Kendall MD: Ultrastructural observations on the hair bulb melanocytes and melanosomes in acute alopecia areata. J Invest Dermatol 94:803-807, 1990
43. Tobin DJ, Fenton DA, Kendall MD: Cell degeneration in alopecia areata. Am J Dermatol 13:248-256, 1991
44. Tobin DJ, Colen SR, Bystryn J-C: Isolation and long-term cultivation of human hair follicle melanocytes. J Invest Dermatol 104:86-89, 1995
45. Weedon D, Strutton G: Apoptosis as the mechanism of the involution of hair follicles in catagen transformation. Acta Derm Venerol 61:335-359, 1981
46. Wyllie AH. Cell death: a new classification separating apoptosis and necrosis. In: Bowen ID, Locksin RA (eds). Cell Death in Biology and Pathology. London: Chapman & Hall, 1981, pp. 9-34
47. Yaar M, Eller MS, Di Benedetto P, et al: The trk family of receptors mediates nerve growth factor and neurotrophin-3 effects in melanocytes. J Clin Invest 94:1550-1562, 1994
48. Young RD: Morphological and ultrastructural aspects of the dermal papilla during the growth cycle of the vibrissal follicle in the rat. J Anat 131:355-365, 1980