메뉴 건너뛰기




Volumn 24, Issue 1, 2011, Pages 165-174

Plexin B1 inhibits integrin-dependent pp125FAK and Rho activity in melanoma

Author keywords

Integrin; Melanoma; Plexin; Rho; Semaphorin

Indexed keywords

FIBRONECTIN; FOCAL ADHESION KINASE 1; GUANINE NUCLEOTIDE BINDING PROTEIN; INTEGRIN; PLEXIN; PLEXIN B1; RHO KINASE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 78651420990     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00797.x     Document Type: Article
Times cited : (14)

References (60)
  • 1
    • 0029092674 scopus 로고
    • Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines
    • Akasaka, T., Van Leeuwen, R.L., Yoshinaga, I.G., Mihm, M.C. Jr, and Byers, H.R. (1995). Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines. J Invest Dermatol 105, 104-108.
    • (1995) J Invest Dermatol , vol.105 , pp. 104-108
    • Akasaka, T.1    Van Leeuwen, R.L.2    Yoshinaga, I.G.3    Mihm Jr, M.C.4    Byers, H.R.5
  • 2
    • 68149160391 scopus 로고    scopus 로고
    • Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells
    • Argast, G.M., Croy, C.H., Couts, K.L., Zhang, Z., Litman, E., Chan, D.C., and Ahn, N.G. (2009). Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells. Oncogene 28, 2697-2709.
    • (2009) Oncogene , vol.28 , pp. 2697-2709
    • Argast, G.M.1    Croy, C.H.2    Couts, K.L.3    Zhang, Z.4    Litman, E.5    Chan, D.C.6    Ahn, N.G.7
  • 3
    • 35648978998 scopus 로고    scopus 로고
    • Structure and mechanics of integrin-based cell adhesion
    • Arnaout, M.A., Goodman, S.L., and Xiong, J.P. (2007). Structure and mechanics of integrin-based cell adhesion. Curr. Opin. Cell Biol. 19, 495-507.
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 495-507
    • Arnaout, M.A.1    Goodman, S.L.2    Xiong, J.P.3
  • 4
    • 0035279067 scopus 로고    scopus 로고
    • Plexins: making links to the cytoskeleton and reducing the GAPs in our knowledge
    • Bagnard, D. (2001). Plexins: making links to the cytoskeleton and reducing the GAPs in our knowledge. Trends Cell Biol. 11, 107.
    • (2001) Trends Cell Biol. , vol.11 , pp. 107
    • Bagnard, D.1
  • 5
    • 27844453850 scopus 로고    scopus 로고
    • p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling
    • Barberis, D., Casazza, A., Sordella, R., Corso, S., Artigiani, S., Settleman, J., Comoglio, P.M., and Tamagnone, L. (2005). p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling. J. Cell Sci. 118(Pt 20), 4689-4700.
    • (2005) J. Cell Sci. , vol.118 , Issue.PT 20 , pp. 4689-4700
    • Barberis, D.1    Casazza, A.2    Sordella, R.3    Corso, S.4    Artigiani, S.5    Settleman, J.6    Comoglio, P.M.7    Tamagnone, L.8
  • 8
    • 2442520826 scopus 로고    scopus 로고
    • Interplay between scatter factor receptors and B plexins controls invasive growth
    • Conrotto, P., Corso, S., Gamberini, S., Comoglio, P.M., and Giordano, S. (2004). Interplay between scatter factor receptors and B plexins controls invasive growth. Oncogene 23, 5131-5137.
    • (2004) Oncogene , vol.23 , pp. 5131-5137
    • Conrotto, P.1    Corso, S.2    Gamberini, S.3    Comoglio, P.M.4    Giordano, S.5
  • 10
    • 1642283154 scopus 로고    scopus 로고
    • Discovery of semaphorin receptors, neuropilin and plexin, and their functions in neural development
    • Fujisawa, H. (2004). Discovery of semaphorin receptors, neuropilin and plexin, and their functions in neural development. J. Neurobiol. 59, 24-33.
    • (2004) J. Neurobiol. , vol.59 , pp. 24-33
    • Fujisawa, H.1
  • 11
    • 77955297403 scopus 로고    scopus 로고
    • R-Ras regulates migration through an interaction with filamin A in melanoma cells. PLos One 23,
    • Gawecka, J.E., Griffiths, G.S., Ek-Rylander, B., Ramos, J.W., Matter, M.L. (2010). R-Ras regulates migration through an interaction with filamin A in melanoma cells. PLos One 23, e11269.
    • (2010)
    • Gawecka, J.E.1    Griffiths, G.S.2    Ek-Rylander, B.3    Ramos, J.W.4    Matter, M.L.5
  • 12
    • 27644439209 scopus 로고    scopus 로고
    • Anoikis
    • Gilmore, A.P. (2005). Anoikis. Cell Death & Differen. 12(Suppl. 2), 1473-1477.
    • (2005) Cell Death & Differen , vol.12 , Issue.SUPPL. 2 , pp. 1473-1477
    • Gilmore, A.P.1
  • 15
    • 38949217077 scopus 로고    scopus 로고
    • Plexin B1 is downregulated in renal cell carcinomas and modulates cell growth
    • Gomez Roman, J.J., Garay, G.O., Saenz, P. et al. (2008). Plexin B1 is downregulated in renal cell carcinomas and modulates cell growth. Transl Res 151, 134-140.
    • (2008) Transl Res , vol.151 , pp. 134-140
    • Gomez Roman, J.J.1    Garay, G.O.2    Saenz, P.3
  • 16
    • 0027343406 scopus 로고
    • met and HGF-SF in normal melanocytes and melanoma cells
    • Halaban, R., Rubin, J.S., and White, W. (1993). met and HGF-SF in normal melanocytes and melanoma cells. Exs 65, 329-339.
    • (1993) Exs , vol.65 , pp. 329-339
    • Halaban, R.1    Rubin, J.S.2    White, W.3
  • 18
    • 0142141199 scopus 로고    scopus 로고
    • Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility
    • Hanks, S.K., Ryzhova, L., Shin, N.Y., and Brabek, J. (2003). Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility. Front Biosci 8, d982-d996.
    • (2003) Front Biosci , vol.8
    • Hanks, S.K.1    Ryzhova, L.2    Shin, N.Y.3    Brabek, J.4
  • 19
    • 70449347073 scopus 로고    scopus 로고
    • Focal adhesion kinase as potential target for cancer therapy (Review)
    • Hao, H., Naomoto, Y., Bao, X. et al. (2009). Focal adhesion kinase as potential target for cancer therapy (Review). Oncol. Rep. 22, 973-979.
    • (2009) Oncol. Rep. , vol.22 , pp. 973-979
    • Hao, H.1    Naomoto, Y.2    Bao, X.3
  • 20
    • 50149083752 scopus 로고    scopus 로고
    • Mammalian Rho GTPases: new insights into their functions from in vivo studies
    • Heasman, S.J., and Ridley, A.J. (2008). Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat. Rev. Mol. Cell Biol. 9, 690-701.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 690-701
    • Heasman, S.J.1    Ridley, A.J.2
  • 22
    • 0029562867 scopus 로고
    • The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases
    • Hotchin, N.A., and Hall, A. (1995). The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases. J. Cell Biol. 131, 1857-1865.
    • (1995) J. Cell Biol. , vol.131 , pp. 1857-1865
    • Hotchin, N.A.1    Hall, A.2
  • 24
    • 0037030464 scopus 로고    scopus 로고
    • The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma
    • Kahana, O., Micksche, M., Witz, I.P., and Yron, I. (2002). The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma. Oncogene 21, 3969-3977.
    • (2002) Oncogene , vol.21 , pp. 3969-3977
    • Kahana, O.1    Micksche, M.2    Witz, I.P.3    Yron, I.4
  • 25
    • 0025376378 scopus 로고
    • Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases
    • Kanner, S.B., Reynolds, A.B., Vines, R.R., and Parsons, J.T. (1990). Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc. Natl. Acad. Sci. U S A 87, 3328-3332.
    • (1990) Proc. Natl. Acad. Sci. U S A , vol.87 , pp. 3328-3332
    • Kanner, S.B.1    Reynolds, A.B.2    Vines, R.R.3    Parsons, J.T.4
  • 26
    • 58149240678 scopus 로고    scopus 로고
    • A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis
    • Korostylev, A., Worzfeld, T., Deng, S. et al. (2008). A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis. Development 135, 3333-3343.
    • (2008) Development , vol.135 , pp. 3333-3343
    • Korostylev, A.1    Worzfeld, T.2    Deng, S.3
  • 27
    • 70350411154 scopus 로고    scopus 로고
    • Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage
    • Lydolph, M.C., Morgan-Fisher, M., Hoye, A.M., Couchman, J.R., Wewer, U.M., and Yoneda, A. (2009). Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage. Exp. Cell Res. 315, 3312-3324.
    • (2009) Exp. Cell Res. , vol.315 , pp. 3312-3324
    • Lydolph, M.C.1    Morgan-Fisher, M.2    Hoye, A.M.3    Couchman, J.R.4    Wewer, U.M.5    Yoneda, A.6
  • 28
    • 11244258882 scopus 로고    scopus 로고
    • Focal adhesion kinase: in command and control of cell motility
    • Mitra, S.K., Hanson, D.A., and Schlaepfer, D.D. (2005). Focal adhesion kinase: in command and control of cell motility. Nat. Rev. Mol. Cell Biol. 6, 56-68.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 56-68
    • Mitra, S.K.1    Hanson, D.A.2    Schlaepfer, D.D.3
  • 29
    • 33750705891 scopus 로고    scopus 로고
    • Neuronal semaphorins regulate a primary immune response
    • Moretti, S., Procopio, A., Boemi, M., and Catalano, A. (2006). Neuronal semaphorins regulate a primary immune response. Curr Neurovasc Res 3, 295-305.
    • (2006) Curr Neurovasc Res , vol.3 , pp. 295-305
    • Moretti, S.1    Procopio, A.2    Boemi, M.3    Catalano, A.4
  • 30
    • 0033868719 scopus 로고    scopus 로고
    • Molecular basis of semaphorin-mediated axon guidance
    • Nakamura, F., Kalb, R.G., and Strittmatter, S.M. (2000). Molecular basis of semaphorin-mediated axon guidance. J. Neurobiol. 44, 219-229.
    • (2000) J. Neurobiol. , vol.44 , pp. 219-229
    • Nakamura, F.1    Kalb, R.G.2    Strittmatter, S.M.3
  • 31
    • 68549122708 scopus 로고    scopus 로고
    • Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
    • Narumiya, S., Tanji, M., and Ishizaki, T. (2009). Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev. 28, 65-76.
    • (2009) Cancer Metastasis Rev. , vol.28 , pp. 65-76
    • Narumiya, S.1    Tanji, M.2    Ishizaki, T.3
  • 32
    • 20744434543 scopus 로고    scopus 로고
    • Plexins: axon guidance and signal transduction
    • Negishi, M., Oinuma, I., and Katoh, H. (2005). Plexins: axon guidance and signal transduction. Cell. Mol. Life Sci. 62, 1363-1371.
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 1363-1371
    • Negishi, M.1    Oinuma, I.2    Katoh, H.3
  • 34
    • 10644250013 scopus 로고    scopus 로고
    • Molecular dissection of the semaphorin 4D receptor plexin-B1-stimulated R-Ras GTPase-activating protein activity and neurite remodeling in hippocampal neurons
    • Oinuma, I., Katoh, H., and Negishi, M. (2004). Molecular dissection of the semaphorin 4D receptor plexin-B1-stimulated R-Ras GTPase-activating protein activity and neurite remodeling in hippocampal neurons. J. Neurosci. 24, 11473-11480.
    • (2004) J. Neurosci. , vol.24 , pp. 11473-11480
    • Oinuma, I.1    Katoh, H.2    Negishi, M.3
  • 35
    • 33646788001 scopus 로고    scopus 로고
    • Semaphorin 4D/Plexin-B1-mediated R-Ras GAP activity inhibits cell migration by regulating beta(1) integrin activity
    • Oinuma, I., Katoh, H., and Negishi, M. (2006). Semaphorin 4D/Plexin-B1-mediated R-Ras GAP activity inhibits cell migration by regulating beta(1) integrin activity. J. Cell Biol. 173, 601-613.
    • (2006) J. Cell Biol. , vol.173 , pp. 601-613
    • Oinuma, I.1    Katoh, H.2    Negishi, M.3
  • 36
    • 0034693854 scopus 로고    scopus 로고
    • Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement
    • Parsons, J.T., Martin, K.H., Slack, J.K., Taylor, J.M., and Weed, S.A. (2000). Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement. Oncogene 19, 5606-5613.
    • (2000) Oncogene , vol.19 , pp. 5606-5613
    • Parsons, J.T.1    Martin, K.H.2    Slack, J.K.3    Taylor, J.M.4    Weed, S.A.5
  • 37
    • 0037044715 scopus 로고    scopus 로고
    • Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF
    • Perrot, V., Vazquez-Prado, J., and Gutkind, J.S. (2002). Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF. J Biol Chem 277, 43115-43120.
    • (2002) J Biol Chem , vol.277 , pp. 43115-43120
    • Perrot, V.1    Vazquez-Prado, J.2    Gutkind, J.S.3
  • 38
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real time RT-PCR
    • Pfaffl, M.W. (2001). A new mathematical model for relative quantification in real time RT-PCR. Nucleic Acids Res. 29, e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 39
    • 56349094235 scopus 로고    scopus 로고
    • Semaphorins and their receptors in lung cancer
    • Potiron, V.A., Roche, J., and Drabkin, H.A. (2009). Semaphorins and their receptors in lung cancer. Cancer Lett. 273, 1-14.
    • (2009) Cancer Lett. , vol.273 , pp. 1-14
    • Potiron, V.A.1    Roche, J.2    Drabkin, H.A.3
  • 40
    • 27644484968 scopus 로고    scopus 로고
    • Clinging to life: cell to matrix adhesion and cell survival
    • Reddig, P.J., and Juliano, R.L. (2005). Clinging to life: cell to matrix adhesion and cell survival. Cancer Metastasis Rev. 24, 425-439.
    • (2005) Cancer Metastasis Rev. , vol.24 , pp. 425-439
    • Reddig, P.J.1    Juliano, R.L.2
  • 41
    • 0031465588 scopus 로고    scopus 로고
    • The GTP-binding protein Rho
    • Ridley, A.J. (1997). The GTP-binding protein Rho. Int. J. Biochem. Cell Biol. 29, 1225-1229.
    • (1997) Int. J. Biochem. Cell Biol. , vol.29 , pp. 1225-1229
    • Ridley, A.J.1
  • 42
    • 0035575585 scopus 로고    scopus 로고
    • Rho family proteins: coordinating cell responses
    • Ridley, A.J. (2001). Rho family proteins: coordinating cell responses. Trends Cell Biol. 11, 471-477.
    • (2001) Trends Cell Biol. , vol.11 , pp. 471-477
    • Ridley, A.J.1
  • 43
    • 33947202804 scopus 로고    scopus 로고
    • Poor outcome in estrogen receptor-positive breast cancers predicted by loss of plexin B1
    • Rody, A., Holtrich, U., Gaetje, R. et al. (2007). Poor outcome in estrogen receptor-positive breast cancers predicted by loss of plexin B1. Clin. Cancer Res. 13, 1115-1122.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1115-1122
    • Rody, A.1    Holtrich, U.2    Gaetje, R.3
  • 44
    • 59149105217 scopus 로고    scopus 로고
    • Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers--results of a large scale microarray analysis
    • Rody, A., Karn, T., Ruckhaberle, E. et al. (2009). Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers--results of a large scale microarray analysis. Eur. J. Cancer 45, 405-413.
    • (2009) Eur. J. Cancer , vol.45 , pp. 405-413
    • Rody, A.1    Karn, T.2    Ruckhaberle, E.3
  • 45
    • 77349108330 scopus 로고    scopus 로고
    • Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth
    • Routhier, A., Astuccio, M., Lahey, D. et al. (2010). Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth. Oncol. Rep. 23, 861-867.
    • (2010) Oncol. Rep. , vol.23 , pp. 861-867
    • Routhier, A.1    Astuccio, M.2    Lahey, D.3
  • 47
    • 67349193305 scopus 로고    scopus 로고
    • Plexin-B1 is a GTPase activating protein for M-Ras, remodelling dendrite morphology
    • Saito, Y., Oinuma, I., Fujimoto, S., and Negishi, M. (2009). Plexin-B1 is a GTPase activating protein for M-Ras, remodelling dendrite morphology. EMBO Rep 10, 614-621.
    • (2009) EMBO Rep , vol.10 , pp. 614-621
    • Saito, Y.1    Oinuma, I.2    Fujimoto, S.3    Negishi, M.4
  • 48
    • 66849129360 scopus 로고    scopus 로고
    • Rho-GTPase signaling drives melanoma cell plasticity
    • Sanz-Moreno, V., and Marshall, C.J. (2009). Rho-GTPase signaling drives melanoma cell plasticity. Cell Cycle 8, 1484-1487.
    • (2009) Cell Cycle , vol.8 , pp. 1484-1487
    • Sanz-Moreno, V.1    Marshall, C.J.2
  • 49
    • 0029748326 scopus 로고    scopus 로고
    • Parallel human genome analysis: microarray-based expression monitoring of 1000 genes
    • Schena, M., Shalon, D., Heller, R., Chai, A., Brown, P.O., and Davis, R.W. (1996). Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc. Natl Acad. Sci. USA 93, 10614-10619.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 10614-10619
    • Schena, M.1    Shalon, D.2    Heller, R.3    Chai, A.4    Brown, P.O.5    Davis, R.W.6
  • 50
    • 0028982786 scopus 로고
    • pp125FAK in human melanocytes and melanoma: expression and phosphorylation
    • Scott, G., and Liang, H. (1995). pp125FAK in human melanocytes and melanoma: expression and phosphorylation. Exp. Cell Res. 219, 197-203.
    • (1995) Exp. Cell Res. , vol.219 , pp. 197-203
    • Scott, G.1    Liang, H.2
  • 51
    • 0026621292 scopus 로고
    • Molecular mechanisms of human melanocyte attachment to fibronectin
    • Scott, G., Ryan, D.H., and Mccarthy, J.B. (1992). Molecular mechanisms of human melanocyte attachment to fibronectin J Invest Dermatol 99, 787-794.
    • (1992) J Invest Dermatol , vol.99 , pp. 787-794
    • Scott, G.1    Ryan, D.H.2    Mccarthy, J.B.3
  • 52
    • 77952426968 scopus 로고    scopus 로고
    • Plexin B1 suppresses c-met in melanoma: a role for plexin B1 as a tumor-suppressor protein through regulation of c-met
    • Stevens, L., Mcclelland, L., Fricke, A., Williamson, M., Kuo, I., and Scott, G. (2010). Plexin B1 suppresses c-met in melanoma: a role for plexin B1 as a tumor-suppressor protein through regulation of c-met. J Invest Dermatol 30, 1636-1645.
    • (2010) J Invest Dermatol , vol.30 , pp. 1636-1645
    • Stevens, L.1    Mcclelland, L.2    Fricke, A.3    Williamson, M.4    Kuo, I.5    Scott, G.6
  • 53
    • 0027952703 scopus 로고
    • Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility
    • Takaishi, K., Sasaki, T., Kato, M., Yamochi, W., Kuroda, S., Nakamura, T., Takeichi, M., and Takai, Y. (1994). Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility. Oncogene 9, 273-279.
    • (1994) Oncogene , vol.9 , pp. 273-279
    • Takaishi, K.1    Sasaki, T.2    Kato, M.3    Yamochi, W.4    Kuroda, S.5    Nakamura, T.6    Takeichi, M.7    Takai, Y.8
  • 54
    • 33744815942 scopus 로고    scopus 로고
    • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis
    • Takegahara, N., Takamatsu, H., Toyofuku, T. et al. (2006). Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis. Nat. Cell Biol. 8, 615-622.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 615-622
    • Takegahara, N.1    Takamatsu, H.2    Toyofuku, T.3
  • 56
    • 0030419430 scopus 로고    scopus 로고
    • Key determinants of the invasion mechanism of melanoma. Role for a new signaling pathway
    • Timar, J., Tovari, J., Szekeres, K., Kagawa, D., and Honn, K.V. (1997). Key determinants of the invasion mechanism of melanoma. Role for a new signaling pathway. Adv. Exp. Med. Biol. 407, 303-310.
    • (1997) Adv. Exp. Med. Biol. , vol.407 , pp. 303-310
    • Timar, J.1    Tovari, J.2    Szekeres, K.3    Kagawa, D.4    Honn, K.V.5
  • 57
    • 0031854558 scopus 로고    scopus 로고
    • The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review)
    • To, C.T., and Tsao, M.S. (1998). The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review). Oncol. Rep. 5, 1013-1024.
    • (1998) Oncol. Rep. , vol.5 , pp. 1013-1024
    • To, C.T.1    Tsao, M.S.2
  • 58
    • 70349332774 scopus 로고    scopus 로고
    • Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility
    • Tomar, A., and Schlaepfer, D.D. (2009). Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility. Curr. Opin. Cell Biol. 21, 676-683.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 676-683
    • Tomar, A.1    Schlaepfer, D.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.