메뉴 건너뛰기




Volumn 118, Issue 20, 2005, Pages 4689-4700

p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling

Author keywords

GAP; p190; Plexin; Semaphorin

Indexed keywords

ACTIN; INTEGRIN; PLEXIN; PROTEIN P190; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SEMAPHORIN; SMALL INTERFERING RNA;

EID: 27844453850     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02590     Document Type: Article
Times cited : (73)

References (68)
  • 1
    • 0034604710 scopus 로고    scopus 로고
    • Phosphorylation of collapsin response mediator protein-2 by Rho-kinase: Evidence for two separate signaling pathways for growth cone collapse
    • Arimura, N., Inagaki, N., Chihara, K., Menager, C., Nakamura, N., Amano, M., Iwamatsu, A., Goshima, Y. and Kaibuchi, K. (2000). Phosphorylation of collapsin response mediator protein-2 by Rho-kinase: Evidence for two separate signaling pathways for growth cone collapse. J. Biol. Chem. 273, 23973-23980.
    • (2000) J. Biol. Chem. , vol.273 , pp. 23973-23980
    • Arimura, N.1    Inagaki, N.2    Chihara, K.3    Menager, C.4    Nakamura, N.5    Amano, M.6    Iwamatsu, A.7    Goshima, Y.8    Kaibuchi, K.9
  • 2
    • 0042922829 scopus 로고    scopus 로고
    • Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: A mechanism for growth cone collapse
    • Atwal, J. K., Singh, K. K., Tessier-Lavigne, M., Miller, F. D. and Kaplan, D. R. (2003). Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse. J Neurosci. 23,7602-7609.
    • (2003) J. Neurosci. , vol.23 , pp. 7602-7609
    • Atwal, J.K.1    Singh, K.K.2    Tessier-Lavigne, M.3    Miller, F.D.4    Kaplan, D.R.5
  • 3
    • 0037126064 scopus 로고    scopus 로고
    • The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG
    • Aurandt, J., Vikis, H. G., Gutkind, J. S., Ahn, N. and Guan, K. L. (2002). The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG. Proc. Natl. Acad Sci. USA 99, 12085-12090.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12085-12090
    • Aurandt, J.1    Vikis, H.G.2    Gutkind, J.S.3    Ahn, N.4    Guan, K.L.5
  • 4
    • 2442421626 scopus 로고    scopus 로고
    • Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility
    • Barberis, D., Artigiani, S., Casazza, A., Corso, S., Giordano, S., Love, C. A., Jones, E. Y., Comoglio, P. M. and Thmagnone, L. (2004). Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility. FASEB J 18, 592-594.
    • (2004) FASEB J. , vol.18 , pp. 592-594
    • Barberis, D.1    Artigiani, S.2    Casazza, A.3    Corso, S.4    Giordano, S.5    Love, C.A.6    Jones, E.Y.7    Comoglio, P.M.8    Thmagnone, L.9
  • 5
    • 0029858256 scopus 로고    scopus 로고
    • Semaphorin III is needed for normal patterning and growth of nerves, bones and heart
    • Behar, O., Golden, J. A., Mashimo, H., Schoen, F. J. and Fishman, M. C. (1996). Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature 383, 525-528.
    • (1996) Nature , vol.383 , pp. 525-528
    • Behar, O.1    Golden, J.A.2    Mashimo, H.3    Schoen, F.J.4    Fishman, M.C.5
  • 6
    • 3042796979 scopus 로고    scopus 로고
    • GAP control: Regulating the regulators of small GTPases
    • Bernards, A. and Settleman, J. (2004). GAP control: regulating the regulators of small GTPases. Trends Cell Biol. 14, 377-385.
    • (2004) Trends Cell Biol. , vol.14 , pp. 377-385
    • Bernards, A.1    Settleman, J.2
  • 7
    • 85047693077 scopus 로고    scopus 로고
    • Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype
    • Bielenberg, D. R., Hida, Y., Shimizu, A., Kaipainen, A., Kreuter, M., Kim, C. C. and Klagsbrun, M. (2004). Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype. J. Clin. Invest. 114, 1260-1271.
    • (2004) J. Clin. Invest. , vol.114 , pp. 1260-1271
    • Bielenberg, D.R.1    Hida, Y.2    Shimizu, A.3    Kaipainen, A.4    Kreuter, M.5    Kim, C.C.6    Klagsbrun, M.7
  • 10
    • 0035071323 scopus 로고    scopus 로고
    • p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation
    • Brouns, M. R., Matheson, S. F. and Settleman, J. (2001). p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat. Cell Biol. 3, 361-367.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 361-367
    • Brouns, M.R.1    Matheson, S.F.2    Settleman, J.3
  • 12
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp, T. R., Bernards, R. and Agami, R. (2002). A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 13
    • 0032570011 scopus 로고    scopus 로고
    • Cloning, genomic organization and chromosomal assignment of the mouse p19O-B gene
    • Burbelo, P. D., Finegold, A. A., Kozak, C. A., Yamada, Y. and Takami, H. (1998). Cloning, genomic organization and chromosomal assignment of the mouse p19O-B gene. Biochim. Biophys. Acta 1443, 203-210.
    • (1998) Biochim. Biophys. Acta , vol.1443 , pp. 203-210
    • Burbelo, P.D.1    Finegold, A.A.2    Kozak, C.A.3    Yamada, Y.4    Takami, H.5
  • 14
    • 1642421365 scopus 로고    scopus 로고
    • Actin cytoskeleton remodelling via local inhibition of contractility at discrete microdomains
    • Burgstaller, G. and Gimona, M. (2004). Actin cytoskeleton remodelling via local inhibition of contractility at discrete microdomains. J Cell Sci. 117, 223-231.
    • (2004) J. Cell Sci. , vol.117 , pp. 223-231
    • Burgstaller, G.1    Gimona, M.2
  • 16
    • 2442520826 scopus 로고    scopus 로고
    • Interplay between scatter factor receptors and B plexins controls invasive growth
    • Conrotto, P., Corso, S., Gamberini, S., Comoglio, P. M. and Giordano, S. (2004). Interplay between scatter factor receptors and B plexins controls invasive growth. Oncogene 23, 5131-5137.
    • (2004) Oncogene , vol.23 , pp. 5131-5137
    • Conrotto, P.1    Corso, S.2    Gamberini, S.3    Comoglio, P.M.4    Giordano, S.5
  • 17
    • 0036366387 scopus 로고    scopus 로고
    • Transduction of a gene expression cassette using advanced generation lentiviral vectors
    • De Palma, M. and Naldini, L. (2002). Transduction of a gene expression cassette using advanced generation lentiviral vectors. Methods Enzymol. 346, 514-529.
    • (2002) Methods Enzymol. , vol.346 , pp. 514-529
    • De Palma, M.1    Naldini, L.2
  • 18
    • 0035814887 scopus 로고    scopus 로고
    • Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho
    • Driessens, M. H., Hu, H., Nobes, C. D., Self, A., Jordens, L, Goodman, C.S. and Hall, A. (2001). Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho. Curr. Biol. 11, 339-344.
    • (2001) Curr. Biol. , vol.11 , pp. 339-344
    • Driessens, M.H.1    Hu, H.2    Nobes, C.D.3    Self, A.4    Jordens, L.5    Goodman, C.S.6    Hall, A.7
  • 19
    • 0033013841 scopus 로고    scopus 로고
    • Evidence for collapsin- 1 functioning in the control of neural crest migration in both trunk and hindbrain regions
    • Eickholt, B. J., Mackenzie, S. L., Graham, A., Walsh, E. S. and Doherty, P. (1999). Evidence for collapsin- 1 functioning in the control of neural crest migration in both trunk and hindbrain regions. Development 126, 2181-2189.
    • (1999) Development , vol.126 , pp. 2181-2189
    • Eickholt, B.J.1    Mackenzie, S.L.2    Graham, A.3    Walsh, E.S.4    Doherty, P.5
  • 20
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S. and Hall, A. (2002). Rho GTPases in cell biology. Nature 420, 629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 22
    • 0032959561 scopus 로고    scopus 로고
    • Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation
    • Fincham, V. J., Chudleigh, A. and Frame, M. C. (1999). Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation. J Cell Sci. 112, 947-956.
    • (1999) J. Cell Sci. , vol.112 , pp. 947-956
    • Fincham, V.J.1    Chudleigh, A.2    Frame, M.C.3
  • 25
    • 0034783680 scopus 로고    scopus 로고
    • Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling
    • Hu, H., Marton, T. F. and Goodman, C. S. (2001). Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling. Neuron 32, 39-51.
    • (2001) Neuron , vol.32 , pp. 39-51
    • Hu, H.1    Marton, T.F.2    Goodman, C.S.3
  • 26
    • 0030809301 scopus 로고    scopus 로고
    • Rac 1 mediates collapsin- 1 -induced growth cone collapse
    • Jin, Z. and Strittmatter, S. M. (1997). Rac 1 mediates collapsin- 1 -induced growth cone collapse. J. Neurosci. 17, 6256-6263.
    • (1997) J. Neurosci. , vol.17 , pp. 6256-6263
    • Jin, Z.1    Strittmatter, S.M.2
  • 29
    • 0027787683 scopus 로고
    • The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules
    • Kolodkin, A. L., Matthes, D. J. and Goodman, C. S. (1993). The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. Cell 75, 1389-1399.
    • (1993) Cell , vol.75 , pp. 1389-1399
    • Kolodkin, A.L.1    Matthes, D.J.2    Goodman, C.S.3
  • 30
    • 0033560132 scopus 로고    scopus 로고
    • Myelin and collapsin-1 induce motor neuron growth cone collapse through different pathways: Inhibition of collapse by opposing mutants of rac1
    • Kuhn, T. B., Brown, M. D., Wilcox, C. L., Raper, J. A. and Bamburg, J.R. (1999). Myelin and collapsin-1 induce motor neuron growth cone collapse through different pathways: inhibition of collapse by opposing mutants of rac1. J. Neurosci. 19, 1965-1975.
    • (1999) J. Neurosci. , vol.19 , pp. 1965-1975
    • Kuhn, T.B.1    Brown, M.D.2    Wilcox, C.L.3    Raper, J.A.4    Bamburg, J.R.5
  • 31
    • 0027373701 scopus 로고
    • Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones
    • Luo, Y., Raible, D. and Raper, J. A. (1993). Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 75, 217-227.
    • (1993) Cell , vol.75 , pp. 217-227
    • Luo, Y.1    Raible, D.2    Raper, J.A.3
  • 35
    • 0037853126 scopus 로고    scopus 로고
    • Cadherin engagement inhibits RhoA via p190RhoGAP
    • Noren, N. K., Arthur, W. T. and Burridge, K. (2003). Cadherin engagement inhibits RhoA via p190RhoGAP. J. Biol. Chem. 278, 13615-13618.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13615-13618
    • Noren, N.K.1    Arthur, W.T.2    Burridge, K.3
  • 36
    • 0038491273 scopus 로고    scopus 로고
    • Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells
    • Oinuma, L, Katoh, H., Harada, A. and Negishi, M. (2003). Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells. J Biol. Chem. 278, 25671-25677.
    • (2003) J. Biol. Chem. , vol.278 , pp. 25671-25677
    • Oinuma, L.1    Katoh, H.2    Harada, A.3    Negishi, M.4
  • 37
    • 3843065433 scopus 로고    scopus 로고
    • The Semaphorin 4D receptor Plexin-BI is a GTPase activating protein for R-Ras
    • Oinuma, I., Ishikawa, Y., Katoh, H. and Negishi, M. (2004). The Semaphorin 4D receptor Plexin-BI is a GTPase activating protein for R-Ras. Science 305, 862-865.
    • (2004) Science , vol.305 , pp. 862-865
    • Oinuma, I.1    Ishikawa, Y.2    Katoh, H.3    Negishi, M.4
  • 38
    • 0037320703 scopus 로고    scopus 로고
    • Semaphorin junction: Making tracks toward neural connectivity
    • Pasterkamp, R. J. and Kolodkin, A. L. (2003). Semaphorin junction: making tracks toward neural connectivity. Curr. Opin. Neurobiol. 13, 79-89.
    • (2003) Curr. Opin. Neurobiol. , vol.13 , pp. 79-89
    • Pasterkamp, R.J.1    Kolodkin, A.L.2
  • 39
    • 0043033220 scopus 로고    scopus 로고
    • Semaphorin 7A promotes axon outgrowth through integrins and MAPKs
    • Pasterkamp, R. J., Peschon, J. J., Spriggs, M. K. and Kolodkin, A. L. (2003). Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature 424, 398-405.
    • (2003) Nature , vol.424 , pp. 398-405
    • Pasterkamp, R.J.1    Peschon, J.J.2    Spriggs, M.K.3    Kolodkin, A.L.4
  • 40
    • 0037044715 scopus 로고    scopus 로고
    • Plexin B regulates rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF
    • Perrot, V., Vazquez-Prado, J. and Gutkind, J. S. (2002). Plexin B regulates rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF. J. Biol. Chem. 277, 43115-43120.
    • (2002) J. Biol. Chem. , vol.277 , pp. 43115-43120
    • Perrot, V.1    Vazquez-Prado, J.2    Gutkind, J.S.3
  • 41
    • 0034611809 scopus 로고    scopus 로고
    • Semaphorin 3A is a chemoattractant for cortical apical dendrites
    • Polleux, E, Morrow, T. and Ghosh, A. (2000). Semaphorin 3A is a chemoattractant for cortical apical dendrites. Nature 404, 567-573.
    • (2000) Nature , vol.404 , pp. 567-573
    • Polleux, E.1    Morrow, T.2    Ghosh, A.3
  • 42
    • 0345731237 scopus 로고    scopus 로고
    • Cell migration: Rho GTPases lead the way
    • Raftopoulou, M. and Hall, A. (2004). Cell migration: Rho GTPases lead the way. Dev. Biol. 265, 23-32.
    • (2004) Dev. Biol. , vol.265 , pp. 23-32
    • Raftopoulou, M.1    Hall, A.2
  • 43
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren, X. D., Kiosses, W. B. and Schwartz, M. A. (1999). Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 18, 578-585.
    • (1999) EMBO J. , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 44
    • 0033731010 scopus 로고    scopus 로고
    • Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
    • Ren, X. D., Kiosses, W. B., Sieg, D. J., Otey, C. A., Schlaepfer, D. D. and Schwartz, M. A. (2000). Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover. J. Cell Sci. 113, 3673-3678.
    • (2000) J. Cell Sci. , vol.113 , pp. 3673-3678
    • Ren, X.D.1    Kiosses, W.B.2    Sieg, D.J.3    Otey, C.A.4    Schlaepfer, D.D.5    Schwartz, M.A.6
  • 46
    • 0034550281 scopus 로고    scopus 로고
    • The semaphorin 3A receptor may directly regulate the activity of small GTPases
    • Rohm, B., Rahim, B., Kleiber, B., Hovatta, I. and Puschel, A. W. (2000). The semaphorin 3A receptor may directly regulate the activity of small GTPases. FEBS Lett. 486, 68-72.
    • (2000) FEBS Lett. , vol.486 , pp. 68-72
    • Rohm, B.1    Rahim, B.2    Kleiber, B.3    Hovatta, I.4    Puschel, A.W.5
  • 47
    • 0033577975 scopus 로고    scopus 로고
    • Interplay between Rac and Rho in the control of substrate contact dynamics
    • Rottner, K., Hall, A. and Small, I V. (1999), Interplay between Rac and Rho in the control of substrate contact dynamics. Curr Biol. 9, 640-648.
    • (1999) Curr. Biol. , vol.9 , pp. 640-648
    • Rottner, K.1    Hall, A.2    Small, I.V.3
  • 48
    • 0033569758 scopus 로고    scopus 로고
    • Mouse semaphorin H induces PC 12 cell neurite outgrowth activating Ras-mitogen-activated protein kinase signaling pathway via Ca(2+) influx
    • Sakai, T., Furuyama, T., Ohoka, Y., Miyazaki, N., Fujioka, S., Sugimoto, H., Amasaki, M., Hattori, S., Matsuya, T. and Inagaki, S. (1999). Mouse semaphorin H induces PC 12 cell neurite outgrowth activating Ras-mitogen-activated protein kinase signaling pathway via Ca(2+) influx. J. Biol. Chem. 274, 29666-29671.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29666-29671
    • Sakai, T.1    Furuyama, T.2    Ohoka, Y.3    Miyazaki, N.4    Fujioka, S.5    Sugimoto, H.6    Amasaki, M.7    Hattori, S.8    Matsuya, T.9    Inagaki, S.10
  • 49
    • 3843098333 scopus 로고    scopus 로고
    • Semaphorin 3A stimulates neurite extension and regulates gene expression in PC12 cells
    • Schwamborn, J. C., Fiore, R., Bagnard, D., Kappler, J., Kaltschmidt, C. and Puschel, A. W. (2004). Semaphorin 3A stimulates neurite extension and regulates gene expression in PC12 cells. J. Biol. Chem. 279, 30923-30926.
    • (2004) J. Biol. Chem. , vol.279 , pp. 30923-30926
    • Schwamborn, J.C.1    Fiore, R.2    Bagnard, D.3    Kappler, J.4    Kaltschmidt, C.5    Puschel, A.W.6
  • 50
    • 0034256024 scopus 로고    scopus 로고
    • Signaling networks linking integrins and rho family GTPases
    • Schwartz, M. A. and Shattil, S. J. (2000). Signaling networks linking integrins and rho family GTPases. Trends Biochem. Sci. 25, 388-391.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 388-391
    • Schwartz, M.A.1    Shattil, S.J.2
  • 52
    • 0037014472 scopus 로고    scopus 로고
    • Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology
    • Swiercz, J. M., Kuner, R., Behrens, J. and Offermanns, S. (2002). Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology. Neuron 35, 51-63.
    • (2002) Neuron , vol.35 , pp. 51-63
    • Swiercz, J.M.1    Kuner, R.2    Behrens, J.3    Offermanns, S.4
  • 53
    • 3042546082 scopus 로고    scopus 로고
    • Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2
    • Swiercz, J. M., Kuner, R. and Offermanns, S. (2004). Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2. J. Cell Biol. 165, 869-880.
    • (2004) J. Cell Biol. , vol.165 , pp. 869-880
    • Swiercz, J.M.1    Kuner, R.2    Offermanns, S.3
  • 54
    • 0035105491 scopus 로고    scopus 로고
    • Plexinal autoinhibition by the plexin sema domain
    • Takahashi, T. and Strittmatter, S. M. (2001). Plexinal autoinhibition by the plexin sema domain. Neuron 29, 429-439.
    • (2001) Neuron , vol.29 , pp. 429-439
    • Takahashi, T.1    Strittmatter, S.M.2
  • 56
    • 2442516485 scopus 로고    scopus 로고
    • To move or not to move? Semaphorin signalling in cell migration
    • Tamagnone, L. and Comoglio, P. M. (2004). To move or not to move? Semaphorin signalling in cell migration. EMBO Rep. 5, 356-361.
    • (2004) EMBO Rep. , vol.5 , pp. 356-361
    • Tamagnone, L.1    Comoglio, P.M.2
  • 57
    • 20244364929 scopus 로고    scopus 로고
    • Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates
    • Tamagnone, L., Artigiani, S., Chen, H., He, Z., Ming, G. L, Song, H., Chedotal, A., Winberg, M. L., Goodman, C. S., Poo, M. et al. (1999). Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. Cell 99, 71-80.
    • (1999) Cell , vol.99 , pp. 71-80
    • Tamagnone, L.1    Artigiani, S.2    Chen, H.3    He, Z.4    Ming, G.L.5    Song, H.6    Chedotal, A.7    Winberg, M.L.8    Goodman, C.S.9    Poo, M.10
  • 58
    • 0032545394 scopus 로고    scopus 로고
    • The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain
    • Tatsis, N., Lannigan, D. A. and Macara, I. G. (1998). The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain. J. Biol. Chem. 273, 34631-34638.
    • (1998) J. Biol. Chem. , vol.273 , pp. 34631-34638
    • Tatsis, N.1    Lannigan, D.A.2    Macara, I.G.3
  • 59
    • 12144285611 scopus 로고    scopus 로고
    • Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2
    • Toyofuku, T., Zhang, H., Kumanogoh, A., Takegahara, N., Suto, F., Kamei, J., Aoki, K., Yabuki, M., Hori, M., Fujisawa, H. et al. (2004). Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Genes Dev. 18, 435-447.
    • (2004) Genes Dev. , vol.18 , pp. 435-447
    • Toyofuku, T.1    Zhang, H.2    Kumanogoh, A.3    Takegahara, N.4    Suto, F.5    Kamei, J.6    Aoki, K.7    Yabuki, M.8    Hori, M.9    Fujisawa, H.10
  • 60
    • 0242572067 scopus 로고    scopus 로고
    • A possible role for p190RhoGAP in PKCepsilon-induced morphological effects
    • Troller, U., Raghunath, A. and Larsson, C. (2004). A possible role for p190RhoGAP in PKCepsilon-induced morphological effects. Cell Signal. 16, 245-252.
    • (2004) Cell Signal , vol.16 , pp. 245-252
    • Troller, U.1    Raghunath, A.2    Larsson, C.3
  • 61
    • 4043105621 scopus 로고    scopus 로고
    • The activity of the plexin-A1 receptor is regulated by Rac
    • Turner, L. J., Nicholls, S. and Hall, A. (2004). The activity of the plexin-A1 receptor is regulated by Rac. J Biol. Chem. 279, 33199-33205.
    • (2004) J. Biol. Chem. , vol.279 , pp. 33199-33205
    • Turner, L.J.1    Nicholls, S.2    Hall, A.3
  • 62
    • 0036570588 scopus 로고    scopus 로고
    • Role of Rho family GTPases in epithelial morphogenesis
    • Van Aelst, L. and Symons, M. (2002). Role of Rho family GTPases in epithelial morphogenesis. Genes Dev. 16, 1032-1054.
    • (2002) Genes Dev. , vol.16 , pp. 1032-1054
    • Van Aelst, L.1    Symons, M.2
  • 63
    • 0032831382 scopus 로고    scopus 로고
    • Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization
    • Vincent, S. and Settleman, J. (1999). Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization. Eur J. Cell Biol. 78, 539-548.
    • (1999) Eur. J. Cell Biol. , vol.78 , pp. 539-548
    • Vincent, S.1    Settleman, J.2
  • 64
    • 0036222784 scopus 로고    scopus 로고
    • Adhesion assembly, disassembly and turnover in migrating cells - Over and over and over again
    • Webb, D. J., Parsons, J. T. and Horwitz, A. F. (2002). Adhesion assembly, disassembly and turnover in migrating cells - over and over and over again. Nat. Cell Biol. 4, E97-E100.
    • (2002) Nat. Cell Biol. , vol.4
    • Webb, D.J.1    Parsons, J.T.2    Horwitz, A.F.3
  • 66
    • 0034782822 scopus 로고    scopus 로고
    • The transmembrane protein Off-track associates with Plexins and functions downstream of Semaphorin signaling during axon guidance
    • Winberg, M. L., Tamagnone, L., Bai, J., Comoglio, P. M., Montell, D. and Goodman, C. S. (2001). The transmembrane protein Off-track associates with Plexins and functions downstream of Semaphorin signaling during axon guidance. Neuron 32, 53-62.
    • (2001) Neuron , vol.32 , pp. 53-62
    • Winberg, M.L.1    Tamagnone, L.2    Bai, J.3    Comoglio, P.M.4    Montell, D.5    Goodman, C.S.6
  • 67
    • 0038037737 scopus 로고    scopus 로고
    • RhoA and ROCK promote migration by limiting membrane protrusions
    • Worthylake, R. A. and Burridge, K. (2003). RhoA and ROCK promote migration by limiting membrane protrusions. J. Biol. Chem. 278, 13578-13584.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13578-13584
    • Worthylake, R.A.1    Burridge, K.2
  • 68
    • 0037080330 scopus 로고    scopus 로고
    • Antagonistic effects of Rnd1 and RboD GTPases regulate receptor activity in Seaphorin 3A-induced cytoskeletal collapse
    • Zanata, S. M., Hovatta, I., Rohm, B. and Puschel, A. W. (2002). Antagonistic effects of Rnd1 and RboD GTPases regulate receptor activity in Seaphorin 3A-induced cytoskeletal collapse. J. Neurosci. 22, 471-477.
    • (2002) J. Neurosci. , vol.22 , pp. 471-477
    • Zanata, S.M.1    Hovatta, I.2    Rohm, B.3    Puschel, A.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.