Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth

Oncology Reports

Volumn 23, Issue 3, 2010, Pages 861-867

  Routhier, Alissa ^a   Astuccio, Michelle ^a   Lahey, Deanna ^a   Monfredo, Nicholas ^a   Johnson, Alyssa ^a   Callahan, William ^a   Partington, Amy ^a   Fellows, Kelly ^a   Ouellette, Lori ^a   Zhidro, Sofiela ^a   Goodrow, Carrie ^a   Smith, Alexis ^a   Sullivan, Kaitlyn ^a   Simone, Peter ^a   Le, Leo ^a   Vezuli, Bora ^a   Zohni, Micheline ^a   West, Elizabeth ^a   Gleason, Daniel ^a   Bryan, Brad ^a  

^a WORCESTER STATE UNIVERSITY   (United States)

Author keywords

Melanoma; Rho kinase; RhoA; ROCK; Small GTPase; Y 27632

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; RHO KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER INVASION; CARCINOGENESIS; CARCINOGENICITY; CELL SURVIVAL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR VOLUME;

AMIDES; ANIMALS; CELL LINE, TUMOR; HUMANS; INJECTIONS, INTRAPERITONEAL; MELANOMA; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; PROTEIN KINASE INHIBITORS; PYRIDINES; RHO-ASSOCIATED KINASES;

EID: 77349108330     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000708     Document Type: Article

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