Requirement for Rho in Integrin Signalling

Cell Communication and Adhesion

Volumn 4, Issue 6, 1997, Pages 387-398

  Barry, Simon T ^a   Flinn, Helen M ^b   Humphries, Martin J ^c   Critchley, David R ^a   Ridley, Anne J ^d  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Actin cytoskeleton; Focal adhesions; Integrins; Rho; Tyrosine phosphorylation

Indexed keywords

INTEGRIN; RHO FACTOR; SCLEROPROTEIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL STRAIN 3T3; CYTOSKELETON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

3T3 CELLS; ACTINS; ADP RIBOSE TRANSFERASES; ANIMALS; BOTULINUM TOXINS; CELL ADHESION; CELL ADHESION MOLECULES; CULTURE MEDIA, SERUM-FREE; CYTOSKELETAL PROTEINS; FIBRONECTINS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GTP-BINDING PROTEINS; INTEGRINS; MICE; NUCLEAR PROTEINS; OLIGOPEPTIDES; PAXILLIN; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0030963016     PISSN: 10615385     EISSN: None     Source Type: Journal    
DOI: 10.3109/15419069709004456     Document Type: Article

References (36)

1. Auer, K. L. and Jacobson, B. S (1995). β1 Integrins signal lipid second messengers required during cell adhesion. Mol. Cell Biol. 6, 1305-1313.
2. Barry, S. T. and Critchley, D. R. (1994). The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-δ to focal adhesions. J. Cell Sci. 107, 2033-2045
3. Bockholt, S. M and Burridge, K. (1993) Cell spreading on extracellular matrix proteins induces tyrosine phosphorylation of tensin. J. Biol. Chem. 268, 14565-14567
4. FAK accompanies cell adhesion to extracellular matrix. A role in cytoskeletal assembly. J Cell Biol 119, 893-903.
5. Chong, L. D., Traynor-Kaplan A., Bokoch, G. M. and Schwartz, M. A. (1994). The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79, 507-513.
6. Du. X., Plow, E F., Frelinger, A. L., O'Toole, T E., Loftus, J. C and Ginsberg, M. H. (1991). Ligands "activate" integrin αIIbβ3 (platelet GPIIb-IIIa). Cell 65, 409-416.
7. Flinn, H. M. and Ridley, A. J. (1996). Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin. J Cell Sci. 109, 1133-1141.
8. Hayashi, Y., Haimovich, B., Reszka, A., Boettiger, D. and Horwitz, A. (1990). Expression and function of chicken integrin β1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells. J. Cell Biol. 110, 175-184.
9. Hotchin, N. A. and Hall, A. (1995). The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases J. Cell Biol 131, 1857-1865.
10. Ilic, D., Furuta, Y., Kanazawa, S., Takeda, N , Sobue, K., Nakatsuji, N., Nomura, S., Fujimoto, J., Okada, M., Yamamoto, T and Aizawa, S. (1995) Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature. 377, 539-543
11. Jockush, B. M., Bubeck, P., Giehl, K , Kroemker, M , Moschner, J., Rothkegel, M., Rudiger, M , Schluter, K., Stanke, G. and Winkler, J. (1995). The molecular architecture of focal adhesions. Annu. Rev. Cell Dev. Biol. 11, 379-416.
12. Kumagai, N., Morii, N., Fujisawa, K., Nemoto, Y. and Narumiya, S. (1993). ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cells. J. Biol Chem. 268, 24535-24538.
13. LaFlamme, S. E., Akiyama, S. K. and Yamada, K. (1992). Regulation of fibronectin receptor distribution. J. Cell Biol. 117, 437-447
14. Leevers, S J. and Marshall, C J. (1992). Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein EMBO J. 11, 569-574.
15. Luna, E J. and Hitt, A L. (1992) Cytoskeleton-plasma membrane interactions Science 258, 955-964.
16. Machesky, L. M. and Pollard, T. D. (1993). Profilin as a potential mediator of membrane-cytoskelton communication. Trends Cell Biol 3, 381-385.
17. Miyamoto, S. Akiyama, S. K and Yamada, K (1995). Synergisitic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 267, 883-885.
18. Moolinaar, W. H. (1994). LPA: a novel lipid mediator with diverse biological actions. Trends Cell Biol. 4, 213-218.
19. Morii, N., Teru-uchi, T., Tominaga, T., Kumagai, N , Kozaki, S , Ushikubi, F. and Narumiya, S. (1992). A Rho gene product in human blood platelets. J Biol. Chem. 267, 20921-20926.
20. Morris, J. D. H., Price, B., Lloyd, A. C., Self, A J., Marshall, C. J. and Hall, A. (1989). Scrape loading of Swiss 3T3 cells with ras protein rapidly activates protein kinase C in the absence of phosphosinositide hydrolysis. Oncogene 4, 27-31.
21. Nobes, C. D., Hawkins, P., Stephens, L. and Hall, A. (1995) Activation of the small GTP-binding proteins Rho and rac by growth factor receptors. J Cell Sci. 108, 225-233.
22. Nobes, C. D and Hall, A. (1995). Rho, Rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibres, lamellipodia and filopodia Cell. 81, 53-62
23. O'Toole, T. E., Katagiri, Y., Faull, R. J , Peter, K., Tamura, R., Quaranta, V., Loftus, J. C., Shattil, S. J. and Ginsberg, M. H. (1994). Integrin cytoplasmic domains mediate inside-out signal transduction J Cell Biol. 124, 1047-1059.
24. Rho induces rapid changes in cell morphology. J. Cell Biol 111, 1001-1007.
25. Petch, L., Bockholt, S M., Bouton, A. Parsons, J. T. and Burridge, K. (1995) Adhesion-induced tyrosine phosphorylation of the p130 SRC substrate. J Cell Sci. 108, 1371-1379.
26. FAK and paxillin induced by bombesin and endothelin. FEBS letters. 354, 315-319
27. Reinhard, J., Scheel, A. A., Diekmann, D., Hall, A., Ruppert, C. and Bahler, M. (1995) A novel type of myosin implicated in signaling by Rho family GTPases. EMBO J. 14, 697-704.
28. Ridley, A. J. and Hall, A. (1992) The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibres in response to growth factors. Cell 70, 389-399.
29. Ridley, A. J. and Hall, A. (1994). Signal transduction pathways regulating Rho mediated stress fibres formation: requirement for a tyrosine kinase. EMBO J 13, 2600-2610.
30. Seufferlein, T and Rozengurt, E. (1994). Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesions kinase. paxillin and p130 J. Biol. Chem. 269, 9345-9351
31. Stossel, T. P (1993). On the crawling of animals cells Science 260, 1086-1094.
32. 1 integrin-mediated cell spreading on fibronectin. J. Biol. Chem. 268, 29, 21459-21462.
33. Werb, Z., Tremble, P. M., Behrendtsen, O., Crowley, E. and Damsky, C H. (1989). Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J. Cell Biol. 109, 887-889.
34. Woods, A and Couchman, J. R. (1992). Protein kinase C involvement in focal adhesion formation. J. Cell Sci. 101, 277-290
35. Yamamoto, M., Marui, N., Sakai, T , Morii, N , Kozaki, S., Ikai, K., Imamura, S. and Narumiya, S. (1993). ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle. Oncogene 8, 1449-1455.
36. Ylanne, J., Chen, Y , O'Toole, T. E., Loftus, J. C , Takada, Y. and Ginsbserg, M. H. (1993) Distinct functions of integrin α and β subunit cytoplasmic domains in cell spreading and formation of focal adhesions. J. Cell Biol. 122, 223-233.