-
1
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007 ; 26:3291-310.
-
(2007)
Oncogene
, vol.26
, pp. 3291-3310
-
-
Roberts, P.J.1
Der, C.J.2
-
2
-
-
0037805547
-
RAS oncogenes: The first 30 years
-
Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer 2003;3:459-65.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
3
-
-
0031767247
-
Genetics of RAS signaling in C. elegans
-
Sternberg PW, Han M. Genetics of RAS signaling in C. elegans. Trends Genet 1998;14:466-72.
-
(1998)
Trends Genet
, vol.14
, pp. 466-472
-
-
Sternberg, P.W.1
Han, M.2
-
5
-
-
0027212082
-
Signal transduction. How receptors turn Ras on
-
McCormick F. Signal transduction. How receptors turn Ras on. Nature 1993 ; 363:15-6.
-
(1993)
Nature
, vol.363
, pp. 15-16
-
-
McCormick, F.1
-
6
-
-
0037451803
-
GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
-
Bernards A. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochim Biophys Acta 2003 ; 1603:47-82.
-
(2003)
Biochim Biophys Acta
, vol.1603
, pp. 47-82
-
-
Bernards, A.1
-
7
-
-
0028363670
-
Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila
-
Cutforth T, Rubin GM. Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila. Cell 1994 ; 77:1027-36.
-
(1994)
Cell
, vol.77
, pp. 1027-1036
-
-
Cutforth, T.1
Rubin, G.M.2
-
8
-
-
0030896688
-
The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila
-
van der Straten A, Rommel C, Dickson B, Hafen E. The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila. EMBO J 1997 ; 16:1961-9.
-
(1997)
EMBO J
, vol.16
, pp. 1961-1969
-
-
Van Der Straten, A.1
Rommel, C.2
Dickson, B.3
Hafen, E.4
-
9
-
-
0028786332
-
Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association
-
Schulte TW, Blagosklonny MV, lngui C, Neckers L. Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association. J Biol Chem 1995 ; 270:24585-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 24585-24588
-
-
Schulte, T.W.1
Blagosklonny, M.V.2
Lngui, C.3
Neckers, L.4
-
10
-
-
0033055908
-
P50(cdc37) acting in concert with Hsp90 is required for Raf-1 function
-
Grammatikakis N, Lm JH, Grammatikakis A, et at. p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. Mol Cell Biol 1999 ; 19:1661-72.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1661-1672
-
-
Grammatikakis, N.1
Lm, J.H.2
Grammatikakis, A.3
At, E.4
-
11
-
-
0026630991
-
Corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso
-
Perkins LA, Larsen I, Perrimon N. Corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell 1992 ; 70:225-36.
-
(1992)
Cell
, vol.70
, pp. 225-236
-
-
Perkins, L.A.1
Larsen, I.2
Perrimon, N.3
-
12
-
-
0029984739
-
DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Rasl in Drosophila
-
Raabe T, Riesgo-Escovar J, Liu X, et al. DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Rasl in Drosophila. Cell 1996 ; 85:911-20.
-
(1996)
Cell
, vol.85
, pp. 911-920
-
-
Raabe, T.1
Riesgo-Escovar, J.2
Liu, X.3
-
13
-
-
0033572707
-
Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the sevenless receptor tyrosine kinase
-
Herbst R, Zhang X, Oin J, Simon MA. Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the sevenless receptor tyrosine kinase. EMBO J 1999 ; 18:6950-61.
-
(1999)
EMBO J
, vol.18
, pp. 6950-6961
-
-
Herbst, R.1
Zhang, X.2
Oin, J.3
Simon, M.A.4
-
14
-
-
0032238275
-
Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway
-
Cleghon V, Feldmann P, Ghiglione C, et al. Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway. Mol Cell 1998 ; 2:719-27.
-
(1998)
Mol Cell
, vol.2
, pp. 719-727
-
-
Cleghon, V.1
Feldmann, P.2
Ghiglione, C.3
-
15
-
-
0032559228
-
Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
-
Hacohen N, Kramer S, Sutherland D, et al. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 1998 ; 92:253-63.
-
(1998)
Cell
, vol.92
, pp. 253-263
-
-
Hacohen, N.1
Kramer, S.2
Sutherland, D.3
-
16
-
-
2942568167
-
Modulation of signalling by Sprouty- A developing story
-
Kim HJ, Bar-Sagi D. Modulation of signalling by Sprouty- a developing story. Nat Rev Mol Cell Biol 2004 ; 5:441-50.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 441-450
-
-
Kim, H.J.1
Bar-Sagi, D.2
-
17
-
-
33645739909
-
Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases
-
Jarvis LA, Toenng SJ, Simon MA, et al. Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases. Development 2006 ; 133:1133-42.
-
(2006)
Development
, vol.133
, pp. 1133-1142
-
-
Jarvis, L.A.1
Toenng, S.J.2
Simon, M.A.3
-
18
-
-
34547764975
-
Malfunctions within the CbI interactome uncouple receptor tyrosine kinases from destructive transport
-
Dikic I, Schmidt MH. Malfunctions within the CbI interactome uncouple receptor tyrosine kinases from destructive transport. Eur J Cell Biol 2007 ; 86: 505-12.
-
(2007)
Eur J Cell Biol
, vol.86
, pp. 505-512
-
-
Dikic, I.1
Schmidt, M.H.2
-
19
-
-
0029124883
-
Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl
-
yoon CH, Lee J, Jongeward GD, Sternberg PW. Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl. Science 1995 ; 269:1102-5.
-
(1995)
Science
, vol.269
, pp. 1102-1105
-
-
Yoon, C.H.1
Lee, J.2
Jongeward, G.D.3
Sternberg, P.W.4
-
21
-
-
0029559183
-
The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Rasmediated signal transduction
-
Sundaram M, Han M. The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Rasmediated signal transduction. Cell 1995 ; 83: 889-901.
-
(1995)
Cell
, vol.83
, pp. 889-901
-
-
Sundaram, M.1
Han, M.2
-
22
-
-
0029584327
-
KSR, a novel protein kinase required for RAS signal transduction
-
Therrien M, Chang HC, Solomon NM, et al. KSR, a novel protein kinase required for RAS signal transduction. Cell 1995 ; 83:879-88.
-
(1995)
Cell
, vol.83
, pp. 879-888
-
-
Therrien, M.1
Chang, H.C.2
Solomon, N.M.3
-
23
-
-
0029588204
-
The ksr-1 gene encodes a novel protein kinase involved in Rasmediated signaling in C. elegans
-
Kornfeld K, Horn DB, Horvitz HR. The ksr-1 gene encodes a novel protein kinase involved in Rasmediated signaling in C. elegans. Cell 1995 ; 83:903-13.
-
(1995)
Cell
, vol.83
, pp. 903-913
-
-
Kornfeld, K.1
Horn, D.B.2
Horvitz, H.R.3
-
24
-
-
33645520353
-
A KSR/CNK complex mediated by HyP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila
-
Douziech M, Sahmi M, Laberge G, Themen M. A KSR/CNK complex mediated by HyP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila. Genes Dev 2006 ; 20:807-19.
-
(2006)
Genes Dev
, vol.20
, pp. 807-819
-
-
Douziech, M.1
Sahmi, M.2
Laberge, G.3
Themen, M.4
-
25
-
-
0042172963
-
Deficiency of kinase suppressor of Rasl prevents oncogenic ras signaling in mice
-
Lozano J, Xing R, Cai Z, et al. Deficiency of kinase suppressor of Rasl prevents oncogenic ras signaling in mice. Cancer Res 2003 ; 63:4232-8.
-
(2003)
Cancer Res
, vol.63
, pp. 4232-4238
-
-
Lozano, J.1
Xing, R.2
Cai, Z.3
-
26
-
-
0036239642
-
Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo
-
Nguyen A, Burack WR, Stock JL, et al. Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol 2002 ; 22:3035-45.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3035-3045
-
-
Nguyen, A.1
Burack, W.R.2
Stock, J.L.3
-
27
-
-
34248576576
-
KSR and CNK: Two scaffolds regulating RAS-mediated RAF activation
-
Claperon A, Therrien M. KSR and CNK: two scaffolds regulating RAS-mediated RAF activation. Oncogene 2007;26:3143-58.
-
(2007)
Oncogene
, vol.26
, pp. 3143-3158
-
-
Claperon, A.1
Therrien, M.2
-
28
-
-
0032582663
-
CNK, a RAF-binding multidomain protein required for RAS signaling
-
Therrien M, Wong AM, Rubin GM. CNK, a RAF-binding multidomain protein required for RAS signaling. Cell 1998; 95: 343-53.
-
(1998)
Cell
, vol.95
, pp. 343-353
-
-
Therrien, M.1
Wong, A.M.2
Rubin, G.M.3
-
29
-
-
14844303687
-
Src42 binding activity regulates Drosophila RAF by a novel CNKdependent derepression mechanism
-
Laberge G, Douziech M, Therrien M. Src42 binding activity regulates Drosophila RAF by a novel CNKdependent derepression mechanism. Embo J 2005 ; 24:487-98.
-
(2005)
Embo J
, vol.24
, pp. 487-498
-
-
Laberge, G.1
Douziech, M.2
Therrien, M.3
-
30
-
-
42949170081
-
CNK and Hyp form a discrete dimer by their SAM domains to mediate RAF kinase signaling
-
Rajakulendran T, Sahmi M, Kurinov I, et al. CNK and Hyp form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proc Natl Acad Sci USA 2008 ; 105:2836-41.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2836-2841
-
-
Rajakulendran, T.1
Sahmi, M.2
Kurinov, I.3
-
31
-
-
70349438995
-
A dimerization-dependent mechanism drives RAF catalytic activation
-
Rajakulendran T, Sahmi M, Lefrançois M, et at. A dimerization-dependent mechanism drives RAF catalytic activation. Nature 2009 ; 461: 542-5.
-
(2009)
Nature
, vol.461
, pp. 542-545
-
-
Rajakulendran, T.1
Sahmi, M.2
Lefrançois, M.3
At, E.4
-
32
-
-
77955502882
-
Mécanisme d'activation de!'oncogene BRAF: L'
-
union fait la force
-
Lavoie H, Therrien M. Mécanisme d'activation de !'oncogene BRAF : l'union fait la force. Med Set (Paris) 2010;26:459-60.
-
(2010)
Med Set (Paris)
, vol.26
, pp. 459-460
-
-
Lavoie, H.1
Therrien, M.2
-
33
-
-
0032504106
-
SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans
-
Sieburth DS, Sun Q, Han M. SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans. Cell 1998 ; 94:119-30.
-
(1998)
Cell
, vol.94
, pp. 119-130
-
-
Sieburth, D.S.1
Sun, Q.2
Han, M.3
-
34
-
-
0032499688
-
Soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling. Proc
-
Selfors LM, Schutzman JL, Borland CZ, Stern MJ. Soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling. Proc Natl Acad Sci USA 1998 ; 95:6903-8.
-
(1998)
Natl Acad Sci USA
, vol.95
, pp. 6903-6908
-
-
Selfors, L.M.1
Schutzman, J.L.2
Borland, C.Z.3
Stern, M.J.4
-
35
-
-
0034655536
-
The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf
-
Li W, Han M, Guan KL. The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf. Genes Dev 2000 ; 14:895-900.
-
(2000)
Genes Dev
, vol.14
, pp. 895-900
-
-
Li, W.1
Han, M.2
Guan, K.L.3
-
36
-
-
33646034613
-
A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity
-
Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, et al. A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity. Mol Cell 2006 ; 22:217-30.
-
(2006)
Mol Cell
, vol.22
, pp. 217-230
-
-
Rodriguez-Viciana, P.1
Oses-Prieto, J.2
Burlingame, A.3
-
37
-
-
0030065261
-
Protein phosphatase 2A positively and negatively regulates Rasl-mediated photoreceptor development in Drosophila
-
Wassarman DA, Solomon NM, Chang HC, et at. Protein phosphatase 2A positively and negatively regulates Rasl-mediated photoreceptor development in Drosophila. Genes Dev 1996 ; 10:272-8.
-
(1996)
Genes Dev
, vol.10
, pp. 272-278
-
-
Wassarman, D.A.1
Solomon, N.M.2
Chang, H.C.3
At, E.4
-
39
-
-
0032474838
-
A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity
-
Tzivion G, Luo Z, Avruch J. A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity. Nature 1998 ; 394:88-92.
-
(1998)
Nature
, vol.394
, pp. 88-92
-
-
Tzivion, G.1
Luo, Z.2
Avruch, J.3
-
40
-
-
0030953744
-
Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development
-
Kockel L, Vorbruggen G, Jackie H, et al. Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development. Genes Dev 1997 ; 11:1140-7.
-
(1997)
Genes Dev
, vol.11
, pp. 1140-1147
-
-
Kockel, L.1
Vorbruggen, G.2
Jackie, H.3
-
41
-
-
0030999664
-
14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila
-
Chang HC, Rubin GM. 14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila. Genes Dev 1997 ; 11:1132-9.
-
(1997)
Genes Dev
, vol.11
, pp. 1132-1139
-
-
Chang, H.C.1
Rubin, G.M.2
-
42
-
-
0033214325
-
A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction
-
Sieburth DS, Sundaram M, Howard RM, Han M. A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction. Genes Dev 1999 13: 2562-9.
-
(1999)
Genes Dev
, vol.13
, pp. 2562-2569
-
-
Sieburth, D.S.1
Sundaram, M.2
Howard, R.M.3
Han, M.4
-
43
-
-
0842328578
-
Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase
-
Yoder JH, Chong H, Guan KL, Han M. Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase. EMBO J 2004 ; 23:111-9.
-
(2004)
EMBO J
, vol.23
, pp. 111-119
-
-
Yoder, J.H.1
Chong, H.2
Guan, K.L.3
Han, M.4
-
44
-
-
0033153370
-
PTP-ER, a novel tyrosine phosphatase, functions downstream of Rasl to downregulate MAP kinase during Drosophila eye development
-
Karim FD, Rubin GM. PTP-ER, a novel tyrosine phosphatase, functions downstream of Rasl to downregulate MAP kinase during Drosophila eye development. Mol Cell 1999;3:741-50.
-
(1999)
Mol Cell
, vol.3
, pp. 741-750
-
-
Karim, F.D.1
Rubin, G.M.2
-
45
-
-
0035137910
-
Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 duringC. elegans vulval development
-
Berset T, Hoier EF, Battu G, et al. Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 duringC. elegans vulval development. Science 2001 ; 291:1055-8.
-
(2001)
Science
, vol.291
, pp. 1055-1058
-
-
Berset, T.1
Hoier, E.F.2
Battu, G.3
-
46
-
-
0036176993
-
Isolation and characterization of a Drosophila homologue of mitogen-activated protein kinase phosphatase-3 which has a high substrate specificity towards extracellular-signal-regulated kinase
-
Kim SH, Kwon HB, Kim YS, et al. Isolation and characterization of a Drosophila homologue of mitogen-activated protein kinase phosphatase-3 which has a high substrate specificity towards extracellular-signal-regulated kinase. Biochem J 2002;361:143-51.
-
(2002)
Biochem J
, vol.361
, pp. 143-151
-
-
Kim, S.H.1
Kwon, H.B.2
Kim, Y.S.3
-
47
-
-
0042977583
-
The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER
-
Rintelen F, Hafen E, Nain K. The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER. Development 2003 ; 130:3479-90.
-
(2003)
Development
, vol.130
, pp. 3479-3490
-
-
Rintelen, F.1
Hafen, E.2
Nain, K.3
-
48
-
-
14644437042
-
Conserved cross-interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual-specificity phosphatase MKP3
-
Gomez AR, Lopez-Varea A, Molnar C, et al. Conserved cross-interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual-specificity phosphatase MKP3. Dev Dyn 2005 ; 232: 695-708.
-
(2005)
Dev Dyn
, vol.232
, pp. 695-708
-
-
Gomez, A.R.1
Lopez-Varea, A.2
Molnar, C.3
-
49
-
-
33646244962
-
Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila
-
Baril C, Therrien M. Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila. Dev Biol 2006 ; 294:232-45.
-
(2006)
Dev Biol
, vol.294
, pp. 232-245
-
-
Baril, C.1
Therrien, M.2
-
50
-
-
62449265216
-
The PP2C alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila
-
Baril C, Sahmi M, Ashton-Beaucage D, et al. The PP2C alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila. Genetics 2009;181:567-79.
-
(2009)
Genetics
, vol.181
, pp. 567-579
-
-
Baril, C.1
Sahmi, M.2
Ashton-Beaucage, D.3
-
51
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell 2005; 120:635-47.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
52
-
-
37749015690
-
Conserved regulation of MAP kinase expression by PUF RNA-binding proteins
-
Lee MH, Hook B, Pan G, et al. Conserved regulation of MAP kinase expression by PUF RNA-binding proteins. PLoS Genet 2007 ; 3 : e233.
-
(2007)
PLoS Genet
, vol.3
-
-
Lee, M.H.1
Hook, B.2
Pan, G.3
-
53
-
-
77957766928
-
The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila
-
Ashton-Beaucage D, Udell CM, Lavoie H, et al. The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. Cell 2010 ; 143:251-62.
-
(2010)
Cell
, vol.143
, pp. 251-262
-
-
Ashton-Beaucage, D.1
Udell, C.M.2
Lavoie, H.3
-
54
-
-
77957792654
-
Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene
-
Roignant Jy, Treisman JE. Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene. Cell 2010 ; 143:238-50.
-
(2010)
Cell
, vol.143
, pp. 238-250
-
-
Jy, R.1
Treisman, J.E.2
-
55
-
-
33750887331
-
A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling
-
Friedman A, Perrimon N. A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature 2006 ; 444:230-4.
-
(2006)
Nature
, vol.444
, pp. 230-234
-
-
Friedman, A.1
Perrimon, N.2
|