DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in drosophila

Cell

Volumn 85, Issue 6, 1996, Pages 911-920

  Raabe, Thomas ^a,b   Riesgo Escovar, Juan ^b   Liu, Xiangdong ^b   Bausenwein, Burkhard S ^a   Deak, Peter ^c,d   Maröy, Peter ^c   Hafen, Ernst ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF SZEGED   (Hungary)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; DROSOPHILA; ENZYME ACTIVE SITE; EYE DEVELOPMENT; GENE MUTATION; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0029984739     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81274-X     Document Type: Article

References (56)

1. Allard, J.D., Chang, H.C., Herbst, R., McNeill, H., and Simon, M.A. (1996). The SH2-containing tyrosine phosphatase Corkscrew is required during signaling by Sevenless, Ras1, and Raf. Development 122, 1125-1135.
2. Baker, N.E., and Rubin, G.M. (1989) Effect on eye development of dominant mutations in Drosophila homologue of EGF receptor. Nature 340, 150-153.
3. Basler, K., Christen, B., and Hafen, E. (1991). Ligand-independent activation of the Sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell 64, 1069-1081.
4. Chou, T.B., Noll, E., and Perrimon, N. (1993). Autosomal P[ovoD1] dominant female-sterile insertions in Drosophila and their use in generating germline chimeras. Development 119, 1359-1369.
5. Diaz-Benjumea, F.J., and Hafen, E. (1994). The Sevenless signaling cassette mediates Drosophila EGF receptor function during epidermal development. Development 120, 569-578.
6. Dickson, B., Sprenger, F., Morrison, D., and Hafen, E. (1992a) Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360, 600-603.
7. Dickson, B., Sprenger, F., and Hafen, E. (1992b). Prepattern in the developing Drosophila eye revealed by an activated torso-sevenless chimeric receptor. Genes Dev. 6, 2327-2339.
8. Dickson, B. (1995). Nuclear factors in sevenless signaling. Trends Genet. 11, 106-111.
9. Duffy, J.B., and Perrimon, N. (1994). The torso pathway in Drosophila: lessons on receptor tyrosine kinase signaling and pattern formation. Dev. Biol. 166, 380-395.
10. Feng, G.-S., Hui, C.-C., and Pawson, T. (1993). SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science 259, 1607-1611.
11. Fortini, M.E., Simon, M.A., and Rubin, G.M. (1992). Signaling by the Sevenless protein-tyrosine kinase is mimicked by Ras1 activation. Nature 355, 559-561.
12. Gaul, U., Mardon, G., and Rubin, G.M. (1992). A putative Ras GTPase-activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase. Cell 68, 1007-1019.
13. Greenwald, I., and Rubin, G.M. (1992). Making a difference: the role of cell-cell interactions in establishing separate identities for equivalent cells. Cell 68, 271-281.
14. Hafen, E., Dickson, B., Raabe, T., Brunner, D., Oellers, N., and van der Straten, A. (1994). Genetic analysis of the Sevenless signal transduction pathway of Drosophila. Development Suppl. 1993, 41-46.
15. Haslam, R.J., Koide, H.B., and Hemmings, B.A. (1993). Pleckstrin domain homology. Nature 363, 309-310.
16. Herbst, R., Carroll, P.M., Allard, J.D., Schilling, J., Raabe, T., and Simon, M.A. Daughter of Sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during Sevenless signaling. Cell 85, this issue.
17. Holgado-Madruga, M., Emlet, D.R., Moscatello, D.K., Godwin, A.K., and Wong, A.J. (1996). A Grb2-associated docking protein in EGF-and insulin-receptor signaling. Nature 379, 560-564.
18. Hou, X.S., Chou, T.-B., Melnick, M.B., and Perrimon, N. (1995). The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway. Cell 81, 63-71.
19. Karlovich, C.A., Bonfini, L., McCollam, L., Rogge, R.D., Daga, A., Czech, M.P., and Banerjee, U. (1995). In vivo functional analysis of the Ras exchange factor Son of Sevenless. Science 268, 576-579.
20. Kazlauskas, A. (1994). Receptor tyrosine kinases and their targets. Curr. Opin. Genet. Dev. 4, 5-14.
21. Klemenz, R., Weber, U., and Gehring, W.J. (1987). The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucl. Acids Res. 15, 3947-3959.
22. Krämer, H., Cagan, R.L., and Zipursky, L.S. (1991). Interaction of Bride of Sevenless membrane-bound ligand and the Sevenless tyrosine-kinase receptor. Nature 352, 207-212.
23. Lewis, E.B., and Bacher, F. (1968). Method of feeding ethyl methanesulfonate to Drosophila males. Dros. Inf. Serv. 43, 193-194.
24. Marshall, C.J. (1994). MAP kinase kinase kinase, MAP kinase kinase, and MAP kinase. Curr. Opin. Genet. Dev. 4, 82-89.
25. Mayer, B.J., Ren, R., Clark, K.L., and Baltimore, D. (1993). A putative modular domain present in diverse signaling proteins. Cell 73, 629-630.
26. McCollam, L., Bonfini, L., Karlovich, C.A., Conway, B.R., Kozma, L.M., Banerjee, U., and Czech, M.P. (1995). Functional roles for the Pleckstrin and Dbl homology regions in the Ras exchange factor Son of Sevenless. J. Biol. Chem. 270, 15954-15957.
27. McCormick, F. (1993). How receptors turn Ras on. Nature 363, 15-16.
28. McCormick, F. (1994). Activators and effectors of ras p21 proteins. Curr. Opin. Genet. Dev. 4, 71-76.
29. Mlodzik, M., Hiromi, Y., Weber, U., Goodman, C.S., and Rubin, G.M. (1990). The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates. Cell 60, 211-224.
30. Musacchio, A., Gibson, T., Rice, P., Thompson, J., and Saraste, M. (1993). The PH domain: a common piece in the structural patchwork of signaling proteins. Trends Biochem. Sci. 18, 343-347.
31. Olivier, J.P., Raabe, T., Henkemayer, M., Dickson, B., Mbamalu, G., Margolis, B., Schlessinger, J., Hafen, E., and Pawson, T. (1993). A Drosophila SH2-SH3 adaptor protein implicated in coupling the Sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, SOS. Cell 73, 179-191.
32. Pawson, T. (1995). Protein modules and signaling networks. Nature 373, 573-580.
33. Perkins, L.A., Larsen, I., and Perrimon, N. (1992). Corkscrew encodes a putative protein-tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell 70, 225-236.
34. Raabe, T., Olivier, J.P., Dickson, B., Liu, X., Gish, G.D., Pawson, T., and Hafen, E. (1995). Biochemical and genetic analysis of the DRK SH2-SH3 adaptor protein of Drosophila. EMBO J. 14, 2509-2518.
35. Robertson, H.M., Preston, C.R., Phillis, R.W., Johnson-Schlitz, D., Benz, W.K., and Engels, W.R. (1988). A stable source of P-element transposase in Drosophila melanogaster. Genetics 118, 461-470.
36. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, Second Edition (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
37. Schlessinger, J. (1994). SH2-SH3 signaling proteins. Curr. Opin. Genet. Dev. 4, 25-30.
38. Shaw, G. (1996). The pleckstrin homology domain: an intriguing multifunctional protein module. Bioessays 18, 35-46.
39. Simon, M.A., Bowtell, D.D., Dodson, G.S., Laverty, T.R., and Rubin, G.M. (1991). Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the Sevenless protein-tyrosine kinase. Cell 67, 701-716.
40. Simon, M.A., Dodson, G.S., and Rubin, G.M. (1993). An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to Sevenless and SOS proteins in vitro. Cell 73, 169-177.
41. Simon, M.A. (1994). Signal transduction during the development of the Drosophila R7 photoreceptor. Dev. Biol. 166, 431-442.
42. Skolnik, E.Y., Batzer, A., Li, N., Lee, C.-H., Lowenstein, E., Mohammadi, M., Margolis, B., and Schlessinger, J. (1993). The function of GRB2 in linking the insulin receptor to Ras signaling pathways. Science 260, 1953-1955.
43. Songyang, Z., Shoelson, S.E., Chaudhuri, M., Gish, G., Pawson, T., Haser, W.G., King, F., Roberts, T., Ratnofsky, S., Lechleider, R.J., Neel, B.G., Birge, R.B., Fajardo, J.E., Chou, M.M., Hanafusa, H., Schaffhausen, B., and Cantley, L.C. (1993). SH2 domains recognize specific phosphopeptide sequences. Cell 72, 767-778.
44. Songyang, Z., Shoelson, S.E., McGlade, J., Olivier, P., Pawson, T., Bustelo, X.R., Barbacid, M., Sabe, H., Hanafusa, H., Yi, T., Ren, R., Baltimore, D., Ratnofsky, S., Feldman, R.A., and Cantley, L.C. (1994). Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/ fes, GRB2, HCP, SHC, Syk, and Vav. Mol. Cell. Biol. 14, 2777-2785.
45. Sprenger, F., and Nüsslein-Volhard, C. (1992). Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg. Cell 71, 987-1001.
46. Stern, M.J., and DeVore, D.L. (1994). Extending and connecting signaling pathways in C. elegans. Dev. Biol. 166, 443-459.
47. Sun, X.J., Crimmins, D.L., Myers, M.G., Miralpeix, M., and White, M.F. (1993). Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1. Mol. Cell. Biol. 13, 7418-7428.
48. Sun, X.J., Wang, L.M., Zhang, Y., Yenush, L.P., Myers, M.G., Glasheen, E., Lane, W.S., Pierce, J.H., and White, M.F. (1995). Role of IRS-2 in insulin and cytokine signaling. Nature 377, 173-177.
49. Szabad, J., Erdélyi, M., Hoffmann, G., Szidonya, J., and Wright, T. (1989). Isolation and characterization of dominant female-sterile mutations of Drosophila melanogaster. mutations on the second chromosome. Genetics 122, 823-835.
50. Tomlinson, A., and Ready, D.F. (1986). Sevenless: a cell-specific homeotic mutation of the Drosophila eye. Science 231, 400-402.
51. Tomlinson, A., Bowtell, D.D.L., Hafen, E., and Rubin, G.M. (1987). Localization of the Sevenless protein, a putative receptor for positional information in the eye imaginai disc of Drosophila. Cell 51, 143-150.
52. Török, T., Tick, G., Alvardo, M., and Kiss, I. (1993). P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster. isolation of lethals with different overgrowth phenotypes. Genetics 135, 71-80.
53. Vogel, W., Lammers, R., Huang, J., and Ullrich, A. (1993). Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science 259, 1611-1614.
54. Wolff, T., and Ready, D.F. (1993). Pattern formation in the Drosophila retina. In The Development of Drosophila melanogaster, M. Bate and A. Martinez-Arias, eds. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), pp. 1277-1326.
55. Xu, T., and Rubin, G.M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
56. Zipursky, L.S., and Rubin, G.M. (1994). Determination of neuronal cell fate: lessons from the R7 neuron in Drosophila. Annu. Rev. Neurosci. 17, 373-397.