Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax

Journal of Biological Chemistry

Volumn 286, Issue 2, 2011, Pages 1134-1146

  Gupta, Subash C ^a   Reuter, Simone ^a   Phromnoi, Kanokkarn ^a   Park, Byoungduck ^a   Hema, Padmanabhan S ^b   Nair, Mangalam ^b   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b REGIONAL RESEARCH LABORATORY CSIR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CHEMICAL ACTIVATION; GENES; GENETIC ENGINEERING; OXYGEN; PROTEINS; REACTIVE OXYGEN SPECIES;

APOPTOTIC PROTEINS; COLON CANCER CELLS; ESTERASE ACTIVITIES; HUMAN COLON CANCER CELLS; INDUCED APOPTOSIS; MITOCHONDRIAL ACTIVITY; PHARMACOLOGICAL INHIBITORS; X-LINKED INHIBITOR OF APOPTOSIS;

DISEASES;

CASPASE; ESTERASE; FLICE INHIBITORY PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NIMBOLIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SURVIVIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER THERAPY; CELL ACTIVITY; CELL SURVIVAL; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY TEST; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG SPECIFICITY; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STABILITY; RECEPTOR UPREGULATION; SENSITIZATION; TRANSCRIPTION REGULATION; TUMOR RESISTANCE;

EID: 78651387590     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.191379     Document Type: Article

References (47)

1. Hanahan, D., and Weinberg, R. A. (2000) Cell 100, 57-70
2. Wiley, S. R., Schooley, K., Smolak, P. J., Din, W. S., Huang, C. P., Nicholl, J. K., Sutherland, G. R., Smith, T. D., Rauch, C., Smith, C. A., et al. (1995) Immunity 3, 673-682
3. Aggarwal, B. B. (2003) Nat. Rev. Immunol. 3, 745-756
4. Pan, G., Ni, J., Wei, Y. F., Yu, G., Gentz, R., and Dixit, V. M. (1997) Science 277, 815-818
5. Pan, G., O'Rourke, K., Chinnaiyan, A. M., Gentz, R., Ebner, R., Ni, J., and Dixit, V. M. (1997) Science 276, 111-113
6. Marsters, S. A., Sheridan, J. P., Donahue, C. J., Pitti, R. M., Gray, C. L., Goddard, A. D., Bauer, K. D., and Ashkenazi, A. (1996) Curr. Biol. 6, 1669-1676
7. Bellail, A. C., Qi, L., Mulligan, P., Chhabra, V., and Hao, C. (2009) Rev. Recent Clin. Trials 4, 34-41
8. MacFarlane, M., Harper, N., Snowden, R. T., Dyer, M. J., Barnett, G. A., Pringle, J. H., and Cohen, G. M. (2002) Oncogene 21, 6809-6818
9. Wagner, K. W., Punnoose, E. A., Januario, T., Lawrence, D. A., Pitti, R. M., Lancaster, K., Lee, D., von Goetz, M., Yee, S. F., Totpal, K., Huw, L., Katta, V., Cavet, G., Hymowitz, S. G., Amler, L., and Ashkenazi, A. (2007) Nat. Med. 13, 1070-1077
10. Hinz, S., Trauzold, A., Boenicke, L., Sandberg, C., Beckmann, S., Bayer, E., Walczak, H., Kalthoff, H., and Ungefroren, H. (2000) Oncogene 19, 5477-5486
11. Clohessy, J. G., Zhuang, J., de Boer, J., Gil-Gómez, G., and Brady, H. J. (2006) J. Biol. Chem. 281, 5750-5759
12. Chawla-Sarkar, M., Bae, S. I., Reu, F. J., Jacobs, B. S., Lindner, D. J., and Borden, E. C. (2004) Cell Death Differ. 11, 915-923
13. Ravi, R., Bedi, G. C., Engstrom, L. W., Zeng, Q., Mookerjee, B., Gélinas, C., Fuchs, E. J., and Bedi, A. (2001) Nat. Cell Biol. 3, 409-416
14. Deveraux, Q. L., Takahashi, R., Salvesen, G. S., and Reed, J. C. (1997) Nature 388, 300-304
15. Ndozangue-Touriguine, O., Sebbagh, M., Mérino, D., Micheau, O., Bertoglio, J., and Bréard, J. (2008) Oncogene 27, 6012-6022
16. Siddiqui, S. (1942) Curr. Sci. 11, 278-279
17. Newman, D. J., Cragg, G. M., and Snader, K. M. (2003) J. Nat. Prod. 66, 1022-1037
18. Anitha, G., Josepha Lourdu Raj, J., Narasimhan, S., Anand Solomon, K., and Rajan, S. S. (2006) J. Asian Nat. Prod. Res. 8, 445-449
19. Rochanakij, S., Thebtaranonth, Y., Yenjai, C., and Yuthavong, Y. (1985) Southeast Asian J. Trop. Med. Public Health 16, 66-72
20. Khalid, S. A., Duddeck, H., and Gonzalez-Sierra, M. (1989) J. Nat. Prod. 52, 922-926
21. Sastry, B. S., Suresh Babu, K., Hari Babu, T., Chandrasekhar, S., Srinivas, P. V., Saxena, A. K., and Madhusudana Rao, J. (2006) Bioorg. Med. Chem. Lett. 16, 4391-4394
22. Roy, M. K., Kobori, M., Takenaka, M., Nakahara, K., Shinmoto, H., Isobe, S., and Tsushida, T. (2007) Phytother. Res. 21, 245-250
23. Gupta, S. C., Prasad, S., Reuter, S., Kannapan, R., Yadav, V. R., Ravindran, J., Hema, P. S., Chaturvedi, M. M., Nair, M., and Aggarwal, B. B. (2010) J. Biol. Chem. 285, 35406-35417
24. Harish Kumar, G., Chandra Mohan, K. V., Jagannadha Rao, A., and Nagini, S. (2009) Invest. New Drugs 27, 246-252
25. Priyadarsini, R. V., Manikandan, P., Kumar, G. H., and Nagini, S. (2009) Free Radic. Res. 43, 492-504
26. Pezzuto, J. M. (1986) in New Trends in Natural Products Chemistry (Atta-ur-Rahaman, LeQuence, P. W., eds) Vol. 26, pp. 371-386, Elsevier Science, Amsterdam, The Netherlands
27. Torres, M., and Forman, H. J. (2003) Biofactors 17, 287-296
28. Nair, M. S., Gopal, S., and Issac, D. (1997) Phytochemistry 46, 1177-1178
29. Bharti, A. C., Donato, N., Singh, S., and Aggarwal, B. B. (2003) Blood 101, 1053-1062
30. Yodkeeree, S., Sung, B., Limtrakul, P., and Aggarwal, B. B. (2009) Cancer Res. 69, 6581-6589
31. Takada, Y., Khuri, F. R., and Aggarwal, B. B. (2004) J. Biol. Chem. 279, 26287-26299
32. Sung, B., Park, B., Yadav, V. R., and Aggarwal, B. B. (2010) J. Biol. Chem. 285, 11498-11507
33. Sethi, G., Ahn, K. S., Pandey, M. K., and Aggarwal, B. B. (2007) Blood 109, 2727-2735
34. Shenoy, K., Wu, Y., and Pervaiz, S. (2009) Cancer Res. 69, 1941-1950
35. Wu, G. S., Burns, T. F., McDonald, E. R., 3rd, Jiang, W., Meng, R., Krantz, I. D., Kao, G., Gan, D. D., Zhou, J. Y., Muschel, R., Hamilton, S. R., Spinner, N. B., Markowitz, S., Wu, G., and el-Deiry, W. S. (1997) Nat. Genet. 17, 141-143
36. Moon, D. O., Kim, M. O., Choi, Y. H., and Kim, G. Y. (2010) Mol. Cancer Ther. 9, 1583-1595
37. Taniguchi, H., Yoshida, T., Horinaka, M., Yasuda, T., Goda, A. E., Konishi, M., Wakada, M., Kataoka, K., Yoshikawa, T., and Sakai, T. (2008) Cancer Res. 68, 8918-8927
38. Kwon, D., Choi, K., Choi, C., and Benveniste, E. N. (2008) Biochem. Biophys. Res. Commun. 372, 870-874
39. Lee, Y. J., Lee, K. H., Kim, H. R., Jessup, J. M., Seol, D. W., Kim, T. H., Billiar, T. R., and Song, Y. K. (2001) Oncogene 20, 1476-1485
40. Wang, R., Li, C., Song, D., Zhao, G., Zhao, L., and Jing, Y. (2007) Cancer Res. 67, 7856-7864
41. Petronelli, A., Saulle, E., Pasquini, L., Petrucci, E., Mariani, G., Biffoni, M., Ferretti, G., Scambia, G., Benedetti-Panici, P., Greggi, S., Cognetti, F., Russo, M. A., Sporn, M., and Testa, U. (2009) Cancer Lett. 282, 214-228
42. Bratton, S. B., and Cohen, G. M. (2003) Cell Death Differ. 10, 4-6
43. LeBlanc, H., Lawrence, D., Varfolomeev, E., Totpal, K., Morlan, J., Schow, P., Fong, S., Schwall, R., Sinicropi, D., and Ashkenazi, A. (2002) Nat. Med. 8, 274-281
44. Review (1993) CA Can. J. Clin. 43, 47-56
45. López-Lázaro, M. (2007) Cancer Lett. 252, 1-8
46. Holman, R. A. (1957) Nature 179, 1033
47. Jeffree, G. M. (1958) Nature 182, 892