Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells

Human Immunology

Volumn 72, Issue 2, 2011, Pages 115-123

  Parmigiani, Anita ^a   Pallin, Maria F ^a   Schmidtmayerova, Helena ^a   Lichtenheld, Mathias G ^a   Pahwa, Savita ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

CD8 T lymphocytes; Cytotoxicity; HIV; IL 21; Immunotherapy

Indexed keywords

INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; INTERLEUKIN 7;

ANTIVIRAL ACTIVITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL ACTIVITY; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, CD28; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; GRANZYMES; HIV INFECTIONS; HIV-1; HUMANS; IMMUNITY, CELLULAR; INTERLEUKIN-15; INTERLEUKIN-2; INTERLEUKIN-7; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MICE; PERFORIN; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; VIRAL LOAD; VIRUS REPLICATION;

EID: 78651260395     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.10.015     Document Type: Article

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