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Volumn 22, Issue 2, 2011, Pages 142-152

Hyperinsulinemia and ectopic fat deposition can develop in the face of hyperadiponectinemia in young obese rats

Author keywords

Adiponectin; FAT CD36; High fat; Non alcoholic fatty liver disease; Pediatric obesity; Total enteral nutrition

Indexed keywords

ADENYLATE KINASE; ADIPONECTIN; FATTY ACID; FATTY ACID TRANSPORTER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TUMOR NECROSIS FACTOR ALPHA;

EID: 78651236375     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2010.01.001     Document Type: Article
Times cited : (12)

References (51)
  • 1
    • 34447633011 scopus 로고    scopus 로고
    • Update on non-alcoholic fatty liver disease in children
    • Papandreou D., Rousso I., Mavromichalis I. Update on non-alcoholic fatty liver disease in children. Clin Nutr 2007, 26:409-415.
    • (2007) Clin Nutr , vol.26 , pp. 409-415
    • Papandreou, D.1    Rousso, I.2    Mavromichalis, I.3
  • 2
    • 42249095244 scopus 로고    scopus 로고
    • Energy-dense, low-fiber, high-fat dietary pattern is associated with increased fatness in childhood
    • Johnson L., Mander A.P., Jones L.R., Emmett P.M., Jebb S.A. Energy-dense, low-fiber, high-fat dietary pattern is associated with increased fatness in childhood. Am J Clin Nutr 2008, 87:846-854.
    • (2008) Am J Clin Nutr , vol.87 , pp. 846-854
    • Johnson, L.1    Mander, A.P.2    Jones, L.R.3    Emmett, P.M.4    Jebb, S.A.5
  • 3
    • 38949187542 scopus 로고    scopus 로고
    • Dietary patterns of adolescents and risk of obesity and hypertension
    • McNaughton S.A., Ball K., Mishra G.D., Crawford D.A. Dietary patterns of adolescents and risk of obesity and hypertension. J Nutr 2008, 138:364-370.
    • (2008) J Nutr , vol.138 , pp. 364-370
    • McNaughton, S.A.1    Ball, K.2    Mishra, G.D.3    Crawford, D.A.4
  • 4
    • 33845994770 scopus 로고    scopus 로고
    • Low-grade systemic inflammation and the risk of type 2 diabetes in obese children and adolescents
    • Syrenicz A., Garanty-Bogacka B., Syrenicz M., Gebala A., Walczak M. Low-grade systemic inflammation and the risk of type 2 diabetes in obese children and adolescents. Neuro Endocrinol Lett 2006, 27:453-458.
    • (2006) Neuro Endocrinol Lett , vol.27 , pp. 453-458
    • Syrenicz, A.1    Garanty-Bogacka, B.2    Syrenicz, M.3    Gebala, A.4    Walczak, M.5
  • 5
    • 53849119153 scopus 로고    scopus 로고
    • The increase of fatty acid-binding protein aP2 in overweight and obese children: interactions with dietary fat and impact on measures of subclinical inflammation
    • Aeberli I., Beljean N., Lehmann R., I'Allemand D., Spinas G.A., Zimmermann M.B. The increase of fatty acid-binding protein aP2 in overweight and obese children: interactions with dietary fat and impact on measures of subclinical inflammation. Int J Obes (Lond) 2008, 32:1513-1520.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 1513-1520
    • Aeberli, I.1    Beljean, N.2    Lehmann, R.3    I'Allemand, D.4    Spinas, G.A.5    Zimmermann, M.B.6
  • 7
    • 34548125265 scopus 로고    scopus 로고
    • Definitive diagnosis and assessment of risk for nonalcoholic fatty liver disease in children and adolescents
    • Schwimmer J.B. Definitive diagnosis and assessment of risk for nonalcoholic fatty liver disease in children and adolescents. Semin Liver Dis 2007, 27:312-318.
    • (2007) Semin Liver Dis , vol.27 , pp. 312-318
    • Schwimmer, J.B.1
  • 9
    • 33847733103 scopus 로고    scopus 로고
    • Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
    • Yamauchi T., Nio Y., Maki T., Kobayashi M., Takazawa T., Iwabu M., et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med 2007, 13:332-339.
    • (2007) Nat Med , vol.13 , pp. 332-339
    • Yamauchi, T.1    Nio, Y.2    Maki, T.3    Kobayashi, M.4    Takazawa, T.5    Iwabu, M.6
  • 10
    • 0037732481 scopus 로고    scopus 로고
    • The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones. Trends in Endocrinol
    • Arner P. The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones. Trends in Endocrinol. Metab. 2003, 14:137-145.
    • (2003) Metab. , vol.14 , pp. 137-145
    • Arner, P.1
  • 11
    • 33646346627 scopus 로고    scopus 로고
    • Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists
    • Nawrocki A.R., Rajala M.W., Tomas E., Pajvani U.B., Saha A.K., Trumbauer M.E., et al. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J Biol Chem 2006, 281:2654-2660.
    • (2006) J Biol Chem , vol.281 , pp. 2654-2660
    • Nawrocki, A.R.1    Rajala, M.W.2    Tomas, E.3    Pajvani, U.B.4    Saha, A.K.5    Trumbauer, M.E.6
  • 12
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A., Wang Y., Keshaw H., Xu L.Y., Lam K.S., Cooper G.J. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003, 112:91-100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 13
    • 34848872799 scopus 로고    scopus 로고
    • Obesity-associated improvements in metabolic profile through expansion of adipose tissue
    • Kim J.Y., van de W.E., Laplante M., Azzara A., Trujillo M.E., Hofmann S.M., et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest 2007, 117:2621-2637.
    • (2007) J Clin Invest , vol.117 , pp. 2621-2637
    • Kim, J.Y.1    van de, W.E.2    Laplante, M.3    Azzara, A.4    Trujillo, M.E.5    Hofmann, S.M.6
  • 15
    • 1542495700 scopus 로고    scopus 로고
    • Decrease in serum adiponectin level due to obesity and visceral fat accumulation in children
    • Asayama K., Hayashibe H., Dobashi K., Uchida N., Nakane T., Kodera K., et al. Decrease in serum adiponectin level due to obesity and visceral fat accumulation in children. Obes Res 2003, 11:1072-1079.
    • (2003) Obes Res , vol.11 , pp. 1072-1079
    • Asayama, K.1    Hayashibe, H.2    Dobashi, K.3    Uchida, N.4    Nakane, T.5    Kodera, K.6
  • 16
    • 0037677604 scopus 로고    scopus 로고
    • Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-α expression
    • Kern P.A., Di Gregorio G.B., Lu T., Rassouli N., Ranganathan G. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-α expression. Diabetes 2003, 52:1779-1785.
    • (2003) Diabetes , vol.52 , pp. 1779-1785
    • Kern, P.A.1    Di Gregorio, G.B.2    Lu, T.3    Rassouli, N.4    Ranganathan, G.5
  • 17
    • 38049120715 scopus 로고    scopus 로고
    • Prevalence of non-alcoholic fatty liver and characteristics in overweight adolescents in the general population
    • Imhof A., Kratzer W., Boehm B., Meitinger K., Trischler G., Steinbach G., et al. Prevalence of non-alcoholic fatty liver and characteristics in overweight adolescents in the general population. Eur J Epidemiol 2007, 22:889-897.
    • (2007) Eur J Epidemiol , vol.22 , pp. 889-897
    • Imhof, A.1    Kratzer, W.2    Boehm, B.3    Meitinger, K.4    Trischler, G.5    Steinbach, G.6
  • 18
    • 18444363335 scopus 로고    scopus 로고
    • Adiponectin, acylation stimulating protein and complement C3 are altered in obesity in very young children
    • Cianflone K., Lu H., Smith J., Yu W., Wang H. Adiponectin, acylation stimulating protein and complement C3 are altered in obesity in very young children. Clin Endocrinol (Oxf) 2005, 62:567-572.
    • (2005) Clin Endocrinol (Oxf) , vol.62 , pp. 567-572
    • Cianflone, K.1    Lu, H.2    Smith, J.3    Yu, W.4    Wang, H.5
  • 19
    • 52149122485 scopus 로고    scopus 로고
    • Impaired adiponectin-AMPK signaling in insulin-sensitive tissues of hypertensive rats
    • Rodriguez A., Catalan V., Becerril S., Gil M.J., Mugueta C., Gomez-Ambrosi J., et al. Impaired adiponectin-AMPK signaling in insulin-sensitive tissues of hypertensive rats. Life Sci 2008, 83:540-549.
    • (2008) Life Sci , vol.83 , pp. 540-549
    • Rodriguez, A.1    Catalan, V.2    Becerril, S.3    Gil, M.J.4    Mugueta, C.5    Gomez-Ambrosi, J.6
  • 20
    • 34047197114 scopus 로고    scopus 로고
    • Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice
    • Bullen J.W., Bluher S., Kelesidis T., Mantzoros C.S. Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. Am J Physiol Endocrinol Metab 2007, 292:E1079-E1086.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Bullen, J.W.1    Bluher, S.2    Kelesidis, T.3    Mantzoros, C.S.4
  • 21
    • 34249693131 scopus 로고    scopus 로고
    • Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies
    • Semple R.K., Halberg N.H., Burling K., Soos M.A., Schraw T., Luan J., et al. Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies. Diabetes 2007, 56:1712-1717.
    • (2007) Diabetes , vol.56 , pp. 1712-1717
    • Semple, R.K.1    Halberg, N.H.2    Burling, K.3    Soos, M.A.4    Schraw, T.5    Luan, J.6
  • 22
    • 0032933114 scopus 로고    scopus 로고
    • Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice
    • Memon R.A., Fuller J., Moser A.H., Smith P.J., Grunfeld C., Feingold K.R. Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice. Diabetes 1999, 48:121-127.
    • (1999) Diabetes , vol.48 , pp. 121-127
    • Memon, R.A.1    Fuller, J.2    Moser, A.H.3    Smith, P.J.4    Grunfeld, C.5    Feingold, K.R.6
  • 23
    • 36849037401 scopus 로고    scopus 로고
    • Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity
    • Koonen D.P., Jacobs R.L., Febbraio M., Young M.E., Soltys C.L., Ong H., et al. Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes 2007, 56:2863-2871.
    • (2007) Diabetes , vol.56 , pp. 2863-2871
    • Koonen, D.P.1    Jacobs, R.L.2    Febbraio, M.3    Young, M.E.4    Soltys, C.L.5    Ong, H.6
  • 24
    • 55949089121 scopus 로고    scopus 로고
    • Contribution of FAT/CD36 to the regulation of skeletal muscle fatty acid oxidation: an overview
    • Holloway G.P., Luiken J.J., Glatz J.F., Spriet L.L., Bonen A. Contribution of FAT/CD36 to the regulation of skeletal muscle fatty acid oxidation: an overview. Acta Physiol (Oxf) 2008, 194:291-309.
    • (2008) Acta Physiol (Oxf) , vol.194 , pp. 291-309
    • Holloway, G.P.1    Luiken, J.J.2    Glatz, J.F.3    Spriet, L.L.4    Bonen, A.5
  • 25
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: defining their role in development of insulin resistance and beta cell dysfunction
    • Boden G., Shulman G.I. Free fatty acids in obesity and type 2 diabetes: defining their role in development of insulin resistance and beta cell dysfunction. Eur J Clin Invest 2002, 32:14-23.
    • (2002) Eur J Clin Invest , vol.32 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 26
    • 56449103294 scopus 로고    scopus 로고
    • A potential role for Akt/FOXO signaling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle
    • Crossland H., Constantin-Teodosiu, Gardiner S.M., Constantin D., Greenhaff P.L. A potential role for Akt/FOXO signaling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle. J Physiol 2008, 586:5589-5600.
    • (2008) J Physiol , vol.586 , pp. 5589-5600
    • Crossland, H.1    Constantin-Teodosiu2    Gardiner, S.M.3    Constantin, D.4    Greenhaff, P.L.5
  • 27
    • 66149102890 scopus 로고    scopus 로고
    • The role of FOXO in the regulation of metabolism. Curr
    • Gross D.N., Wan M., Birnbaum M.J. The role of FOXO in the regulation of metabolism. Curr. Diabetes Rep 2009, 9:208-214.
    • (2009) Diabetes Rep , vol.9 , pp. 208-214
    • Gross, D.N.1    Wan, M.2    Birnbaum, M.J.3
  • 28
    • 33748312093 scopus 로고    scopus 로고
    • Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism
    • Matsumoto M., Han S., Kitamura T., Accili D. Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism. J Clin Invest 2006, 116:2464-2472.
    • (2006) J Clin Invest , vol.116 , pp. 2464-2472
    • Matsumoto, M.1    Han, S.2    Kitamura, T.3    Accili, D.4
  • 29
    • 23444439192 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition
    • Ronis M.J., Butura A., Sampey B.P., Shankar K., Prior R.L., Korourian S., et al. Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition. Free Radic Biol Med 2005, 39:619-630.
    • (2005) Free Radic Biol Med , vol.39 , pp. 619-630
    • Ronis, M.J.1    Butura, A.2    Sampey, B.P.3    Shankar, K.4    Prior, R.L.5    Korourian, S.6
  • 31
    • 38349125024 scopus 로고    scopus 로고
    • A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet
    • Baumgardner J.N., Shankar K., Hennings L., Badger T.M., Ronis M.J. A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet. Am J Physiol Gastrointest Liver Physiol 2008, 294:G27-G38.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Baumgardner, J.N.1    Shankar, K.2    Hennings, L.3    Badger, T.M.4    Ronis, M.J.5
  • 33
    • 33846253661 scopus 로고    scopus 로고
    • Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis
    • Ota T., Takamura T., Kurita S., Matsuzawa N., Kita Y., Uno M., et al. Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. Gastroenterology 2007, 132:282-293.
    • (2007) Gastroenterology , vol.132 , pp. 282-293
    • Ota, T.1    Takamura, T.2    Kurita, S.3    Matsuzawa, N.4    Kita, Y.5    Uno, M.6
  • 34
    • 0141706357 scopus 로고    scopus 로고
    • Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
    • Matsuzaki H., Daitoku H., Hatta M., Tanaka K., Fukamizu A. Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation. Proc Natl Acad Sci U S A 2003, 100:11285-11290.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11285-11290
    • Matsuzaki, H.1    Daitoku, H.2    Hatta, M.3    Tanaka, K.4    Fukamizu, A.5
  • 35
    • 33751095640 scopus 로고    scopus 로고
    • Shirahata A. N-acetylcysteine attenuates TNF-α induced changes in secretion of interleukin-6, plasminogen activator inhibitor-1 and adiponectin from 3T3-L1 adipocytes
    • Araki S., Dobashi K., Kubo K., Yamamoto Y., Asayama K. Shirahata A. N-acetylcysteine attenuates TNF-α induced changes in secretion of interleukin-6, plasminogen activator inhibitor-1 and adiponectin from 3T3-L1 adipocytes. Life Sci 2006, 79:2405-2412.
    • (2006) Life Sci , vol.79 , pp. 2405-2412
    • Araki, S.1    Dobashi, K.2    Kubo, K.3    Yamamoto, Y.4    Asayama, K.5
  • 36
    • 0029910018 scopus 로고    scopus 로고
    • Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
    • Hawley S.A., Davison M., Woods A., Davies S.P., Beri R.K., Carling D., et al. Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J Biol Chem 1996, 271:27879-27887.
    • (1996) J Biol Chem , vol.271 , pp. 27879-27887
    • Hawley, S.A.1    Davison, M.2    Woods, A.3    Davies, S.P.4    Beri, R.K.5    Carling, D.6
  • 38
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia
    • Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R.E., et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001, 86:1930-1935.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3    Hotta, K.4    Matsuzawa, Y.5    Pratley, R.E.6
  • 40
    • 33947657925 scopus 로고    scopus 로고
    • Do low levels of circulating adiponectin represent a biomarker or just another risk factor for the metabolic syndrome?
    • Brooks N.L., Moore K.S., Clark R.D., Perfetti M.T., Trent C.M., Combs T.P. Do low levels of circulating adiponectin represent a biomarker or just another risk factor for the metabolic syndrome?. Diabetes Obes Metab 2007, 9:246-258.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 246-258
    • Brooks, N.L.1    Moore, K.S.2    Clark, R.D.3    Perfetti, M.T.4    Trent, C.M.5    Combs, T.P.6
  • 41
    • 33751512005 scopus 로고    scopus 로고
    • Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome
    • Winer J.C., Zern T.L., Taksali S.E., Dziura J., Cali A.M., Wollschlager M., et al. Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome. J Clin Endocrinol Metab 2006, 91:4415-4423.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4415-4423
    • Winer, J.C.1    Zern, T.L.2    Taksali, S.E.3    Dziura, J.4    Cali, A.M.5    Wollschlager, M.6
  • 42
    • 33846296316 scopus 로고    scopus 로고
    • A high-fat diet has a tissue-specific effect on adiponectin and related enzyme expression
    • Barnea M., Shamay A., Stark A.H., Madar Z. A high-fat diet has a tissue-specific effect on adiponectin and related enzyme expression. Obesity (Silver Spring) 2006, 14:2145-2153.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 2145-2153
    • Barnea, M.1    Shamay, A.2    Stark, A.H.3    Madar, Z.4
  • 43
    • 0030047184 scopus 로고    scopus 로고
    • Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene
    • Varanasi U., Chu R., Huang Q., Castellon R., Yeldandi A.V., Reddy J.K. Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene. J Biol Chem 1996, 271:2147-2155.
    • (1996) J Biol Chem , vol.271 , pp. 2147-2155
    • Varanasi, U.1    Chu, R.2    Huang, Q.3    Castellon, R.4    Yeldandi, A.V.5    Reddy, J.K.6
  • 44
    • 0035024343 scopus 로고    scopus 로고
    • A potent PPAR-α agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle
    • Minnich A., Tian N., Byan L., Bilder G. A potent PPAR-α agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle. Am J Physiol Endocrinol Metab 2001, 280:E270-E279.
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Minnich, A.1    Tian, N.2    Byan, L.3    Bilder, G.4
  • 45
    • 33750578279 scopus 로고    scopus 로고
    • Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor-α
    • Yoon M.J., Lee G.Y., Chung J.J., Ahn Y.H., Hong S.H., Kim J.B. Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor-α. Diabetes 2006, 55:2562-2570.
    • (2006) Diabetes , vol.55 , pp. 2562-2570
    • Yoon, M.J.1    Lee, G.Y.2    Chung, J.J.3    Ahn, Y.H.4    Hong, S.H.5    Kim, J.B.6
  • 47
    • 33745896155 scopus 로고    scopus 로고
    • Recent advances in the relationship between obesity, inflammation, and insulin resistance
    • Bastard J.P., Maachi M., Lagathu C., Kim M.J., Caron M., Vidal H., et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 2006, 17:4-12.
    • (2006) Eur Cytokine Netw , vol.17 , pp. 4-12
    • Bastard, J.P.1    Maachi, M.2    Lagathu, C.3    Kim, M.J.4    Caron, M.5    Vidal, H.6
  • 49
    • 34948831425 scopus 로고    scopus 로고
    • Dose-dependent effects of alcohol on insulin signaling: Partial explanation for biphasic alcohol impact on human health
    • He L., Marecki J.C., Serrero G., Simmen F.A., Ronis M.J.J., Badger T.M. Dose-dependent effects of alcohol on insulin signaling: Partial explanation for biphasic alcohol impact on human health. Mol Endocrinol 2007, 21:2541-2550.
    • (2007) Mol Endocrinol , vol.21 , pp. 2541-2550
    • He, L.1    Marecki, J.C.2    Serrero, G.3    Simmen, F.A.4    Ronis, M.J.J.5    Badger, T.M.6
  • 51
    • 33747047885 scopus 로고    scopus 로고
    • Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action
    • Samuel V.T., Choi C.S., Phillips T.G., Romanelli A.J., Geisler J.G., Bhanot S., et al. Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action. Diabetes 2006, 55:2042-2050.
    • (2006) Diabetes , vol.55 , pp. 2042-2050
    • Samuel, V.T.1    Choi, C.S.2    Phillips, T.G.3    Romanelli, A.J.4    Geisler, J.G.5    Bhanot, S.6


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