Human prostaglandin H synthase (hPHS)-1- and hPHS-2-dependent bioactivation, oxidative macromolecular damage, and cytotoxicity of dopamine, its precursor, and its metabolites

Free Radical Biology and Medicine

Volumn 50, Issue 2, 2011, Pages 295-304

  Ramkissoon, Annmarie ^a   Wells, Peter G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Dopamine; Free radicals; Oxidative stress; Prostaglandin H synthase; Reactive oxygen species

Indexed keywords

3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CATALASE; DOPAMINE; HOMOVANILLIC ACID; PROSTAGLANDIN SYNTHASE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL STRAIN; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; GENETIC TRANSFECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; CATALASE; CHO CELLS; CRICETINAE; CRICETULUS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DEOXYGUANOSINE; DINOPROSTONE; DNA DAMAGE; DOPAMINE; HUMANS; L-LACTATE DEHYDROGENASE; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES;

EID: 78651234518     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.11.010     Document Type: Article

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