Interferon-α and interleukin-12 are induced, respectively, by double-stranded DNA and single-stranded RNA in human myeloid dendritic cells

Immunology

Volumn 132, Issue 2, 2011, Pages 165-173

  Katashiba, Yuichi ^a   Miyamoto, Rie ^a   Hyo, Akira ^a   Shimamoto, Keiko ^a   Murakami, Naoko ^a   Ogata, Makoto ^a   Amakawa, Ryuichi ^a   Inaba, Muneo ^a   Nomura, Shosaku ^a   Fukuhara, Shirou ^a   Ito, Tomoki ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Dendritic cells; Double stranded DNA; Interferon ; Single stranded RNA

Indexed keywords

ALPHA INTERFERON; CHLOROQUINE; DOUBLE STRANDED DNA; INTERLEUKIN 12; SINGLE STRANDED RNA;

ARTICLE; CYTOKINE RELEASE; DNA TRANSFER; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; MYELOID DENDRITIC CELL; PRIORITY JOURNAL;

DENDRITIC CELLS; DNA; HUMANS; IMMUNITY, INNATE; INTERFERON-ALPHA; INTERLEUKIN-12; MONOCYTES; RNA; TOLL-LIKE RECEPTOR 9;

EID: 78650959235     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2010.03350.x     Document Type: Article

References (39)

1. Bogdan C. The function of type I interferons in antimicrobial immunity. Curr Opin Immunol 2000; 12:419-24.
2. Kadowaki N, Antonenko S, Lau JY, Liu YJ. Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J Exp Med 2000; 192:219-26.
3. Steinman RM, Hemmi H. Dendritic cells: translating innate to adaptive immunity. Curr Top Microbiol Immunol 2006; 311:17-56.
4. Takeda K, Kaisho T, Akira S. Toll-like receptors. Annu Rev Immunol 2003; 21:335-76.
5. Janeway CA Jr, Medzhitov R. Innate immune recognition. Annu Rev Immunol 2002; 20:197-216.
6. Kadowaki N, Ho S, Antonenko S, Malefyt RW, Kastelein RA, Bazan F, Liu YJ. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001; 194:863-9.
7. Jarrossay D, Napolitani G, Colonna M, Sallusto F, Lanzavecchia A. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur J Immunol 2001; 31:3388-93.
8. Ito T, Kanzler H, Duramad O, Cao W, Liu YJ. Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells. Blood 2006; 15:2423-31.
9. Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001; 413:732-8.
10. Liu YJ. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol 2005; 23:275-306.
11. Lande R, Gregorio J, Facchinetti V et al. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 2007; 449:564-9.
12. Finke D, Eloranta ML, Rönnblom L. Endogenous type I interferon inducers in autoimmune diseases. Autoimmunity 2009; 42:349-52.
13. Hochrein H, Schlatter B, O'Keeffe M et al. Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways. Proc Natl Acad Sci USA 2004; 101:11416-21.
14. Rasumussen SB, Sørensen LN, Malmgaard L, Ank N, Baines JD, Chen ZJ, Paludan SR. Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems. J Virol 2007; 81:13315-24.
15. Takaoka A, Wang Z, Choi MK et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007; 448:423-4.
16. Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009; 26:514-8.
17. Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, Cao X. The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol 2010; 11:487-94.
18. Felgner JH, Kumar R, Sridhar CN et al. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 1994; 269:2550-61.
19. Heil F, Hemmi H, Hochrein H et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004; 303:1526-9.
20. Ito T, Amakawa R, Kaisho T et al. Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J Exp Med 2002; 195:1507-12.
21. Jurk M, Heil F, Vollmer J, Schetter C, Krieg AM, Wagner H, Lipford G, Bauer S. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 2002; 3:499.
22. Hoene V, Peiser M, Wanner R. Human monocyte-derived dendritic cells express TLR9 and react directly to the CpG-A oligonucleotide D19. J Leukoc Biol 2006; 80:1328-36.
23. Osawa Y, Iho S, Takauji R et al. Collaborative action of NF-kappaB and p38 MAPK is involved in CpG DNA-induced IFN-alpha and chemokine production in human plasmacytoid dendritic cells. J Immunol 2006; 177:4841-52.
24. Hornung V, Schlender J, Guenthner-Biller M, Rothenfusser S, Endres S, Conzelmann KK, Hartmann G. Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus. J Immunol 2004; 173:5935-43.
25. Ishii KJ, Akira S. Innate immune recognition of, and regulation by, DNA. Trends Immunol 2006; 27:523-32.
26. Koyama S, Ishii KJ, Coban C, Akira S. Innate immune responses to viral infection. Cytokine 2008; 43:336-41.
27. Gilliet M, Cao W, Liu YJ. Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat Rev Immunol 2008; 8:594-606.
28. Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 2001; 16:1540-3.
29. Nestle FO, Conrad C, Tun-Kyi A et al. Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med 2005; 202:135-43.
30. Hägele H, Allam R, Pawar RD, Reichel CA, Krombach F, Anders HJ. Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptor-independent cytosolic DNA recognition pathway. Am J Pathol 2009; 175:1896-904.
31. Izaguirre A, Barnes BJ, Amrute S et al. Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells. J Leukoc Biol 2003; 74:1125-38.
32. Miki A, Yano Y, Kato H, Seo Y, Kuriyama M, Azuma T, Hayashi Y. Anti-tumor effect of pegylated interferon in the rat hepatocarcinogenesis model. Int J Oncol 2008; 32:603-8.
33. Moriya F, Ogasawara S, Basaki Y et al. Growth inhibitory effects of pegylated IFN-alpha2b and 5-fluorouracil in combination on renal cell carcinoma cell lines in vitro and in vivo. Int J Oncol 2008; 33:647-55.
34. Scheel B, Teufel R, Probst J et al. Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA. Eur J Immunol 2005; 35:1557-66.
35. Nociari M, Ocheretina O, Schoggins JW, Falck-Pederson E. Sensing infection by adenovirus: toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator. J Virol 2007; 81:4145-57.
36. Hornung V, Guenthner-Biller M, Bourquin C et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med 2005; 11:263-70.
37. Ganguly D, Chamilos G, Lande R et al. Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J Exp Med 2009; 206:1983-94.
38. Ablasser A, Poeck H, Anz D et al. Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes. J Immunol 2009; 182:6824-33.
39. Kato H, Sato S, Yoneyama M et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity 2005; 23:19-28.